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Propylthiouracil (6-n-Propylthiouracil) is a thyroid peroxidase inhibitor and also a 5' -deiodinase inhibitor.

D-mannoheptose is the main non-structural carbohydrate in avocado. D-mannoheptose is a specific inhibitor of D-glucose phosphorylation. D-mannoheptose can prevent the release of insulin and the utilization of carbohydrates in rats.

BPTU (BMS-646786) is an allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM). Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contraction of rat and mouse colon induced by electrical field stimulation, nicotine and P2Y agonists. Antithrombotic; reduces platelet aggregation.

PTUPB is a potent dual inhibitor of sEH and COX-2 enzymes with IC50 values of 0.9 nM and 1.26 μM, respectively.

D-Sedoheptulose 7-phosphate is a common precursor of heptaic acid (group III) and the heptasaccharide of hygromycin B (group IV). This compound can be converted to NDP-heptose via similar biosynthetic pathways present in these substances.

Paracetamol Mercapturate is a metabolite of Acetaminophen. It can also be used in the biological study of urinary antihypertensive drugs.

Clofibrate mercapturate is a urinary metabolite of clofibrate.

Paracetamol mercapturate is a deuterated metabolite of acetaminophen.

Pentachlorophenylmercapturic acid is a bioactive chemical.

Pentylmercapturic acid is a bioactive chemical.

S-Allylmercapturic Acid (N-Acetyl-S-allyl-L-cysteine) is a metabolite of S-allyl-L-cysteine present in black garlic with potential anti-gout effects, inhibiting both CYP2D6 and CYP-catalyzed reactions.

Peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid can give rise to 4-HNE. 4-HNE is cleared rapidly from the plasma and undergoes enterohepatic circulation as a glutathione conjugate in the rat. About two thirds of an administered dose of 4-HNE is excreted within 48 hours in the urine, primarily in the form of mercapturic acid conjugates. The C-1 aldehyde of 4-HNE is reduced to an alcohol in about half of these metabolites. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form γ-lactols and γ-lactones, respectively, producing at least 4 or 5 end urinary metabolites of 4-HNE in vivo.

Atrazine mercapturate is a major, glutathione-derived metabolite of atrazine , an herbicide that is effective in controlling a broad range of weeds. Atrazine has been reported to cause cancer in certain laboratory animals, have diverse effects on the reproductive system in animals and humans, and disrupt the normal function of the endocrine system. Atrazine mercapturate is readily measured in urine samples.

D-Sedoheptulose-7-phosphate is an intermediate in the pentose phosphate pathway. [1] [2] In this pathway, transaldolase catalyzes the transfer of a three carbon dihydroxyacetone moiety from D-sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to generate D-fructose-6-phosphate . D-Sedoheptulose-7-phosphate is also an intermediate in carbon fixation in photosynthetic organisms, as well as in the biosynthesis of lipopolysaccharide, amino acids, secondary metabolites, and antibiotics. [3]

S-Phenylmercapturic acid is a metabolite of benzene that can be used as a biomarker to assess benzene exposure.

Naptumomab, a tumor-targeting superantigen (TTS), is a fusion protein that activates the immune system to recognize and eradicate tumor cells. It shows promise in researching refractory solid tumors, including renal cell carcinoma [1] [2].

Naptumomab estafenatox (ABR-217620) is a fusion protein that combines an anti-5T4 antibody with a SEA E-120 superantigen, categorized as a tumor targeting superantigen (TTS). It has potential applications in lung cancer research [1].

Sedoheptulose anhydride is a natural product.

D-altrofurano-heptulose-3 (alpha-D-Altro-3-heptulofuranose) is isolated from the rhizomes of Actinidia kolomikta (Rupr. & Maxim.) Maxim., Actinidiaceae

Methyl (methyl 3-deoxy-D-arabino-heptulopyranosid)onate-7-phosphate is a biochemical reagent utilized in glycobiology research. Glycobiology explores the structure, synthesis, biology, and evolution of sugars, involving carbohydrate chemistry, glycan formation and degradation, protein-glycan recognition, and the roles of glycans in biological systems. This field is closely linked with fundamental research, biomedicine, and biotechnology.

Rosolutamide (ALZ-003) is a curcumin analog, an orally active Nrf1 and Nrf2 activator.Rosolutamide modulates oxidative homeostasis, improves mitochondrial function and promotes autophagy, reduces mutant protein aggregation, and decreases intracellular mitochondrial reactive oxygen species (ROS) levels.Rosolutamide has been used in the study of neurodegeneration such as spinal cerebellar ataxia and Huntington disease. neurodegenerative diseases such as Huntington's disease. Regulates oxidative homeostasis.

The leguminous shrub,Leucaena leucocephala(Leucaena) is wide‐spread in tropical and subtropical agricultural systems and provides a ready source of protein for livestock. However, the presence of mimosine, a non‐protein, amino acid comprising about 12% of the dry matter in growing tips ofLeucaena, is toxic to animals. Mimosine is degraded rapidly in the rumen to produce 3,4‐dihydroxypyridine (3,4‐DHP) and 2,3‐dihydroxypyridine (2,3‐DHP), both of which remain toxic to animals[1]. 3,4-DHP, as a derivative of the plant amino acid mimosine, is goitrogenic in cattle, sheep, and mice. In contrast to established antithyroid compounds, such as methimazole (MMI) and propylthiouracil (PTU), 3,4-DHP has no SH-group. 3,4-DHP with various concentrations inhibited incorporation of125I into protein in human thyroid slices. It also suppressed the activation of lymphocytes by PHA (phytohaemagglutinin) and PWM (pokeweed mitogen). Suppression with 3,4-DHP was seen at 100 and 1000 μmol L (P< 0.001 vs both PHA and PWM). Those, together with a very low murine bone marrow toxicity, probably related to the absence of an SH-group, make 3,4-DHP a potential antithyroid drug[2].