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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5336 | Zacopride hydrochloride | Potassium Channel , 5-HT Receptor | |
Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist. | |||
T2519 | Lercanidipine | Masnidipine | Calcium Channel |
Lercanidipine (Masnidipine) is a calcium channel blocker of the dihydropyridine class. | |||
T16695 | Pyrintegrin | Integrin | |
Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal... | |||
T0412 | Idebenone | CV-2619 | Apoptosis , Antioxidant , Mitochondrial Metabolism |
Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). | |||
T0081 | Lafutidine | FRG-8813 | 5-HT Receptor , Histamine Receptor |
Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion. | |||
T16812 | RWJ-67657 | JNJ 3026582 | p38 MAPK |
RWJ-67657 (JNJ 3026582) is an orally active and selective p38α and p38β MAPK inhibitor (IC50s: 1 and 11 μM, respectively). RWJ-67657 shows no activity at p38γ and p38δ and shows a cardioprotective effect. | |||
T6874 | Lercanidipine hydrochloride | Corifeo,Carmen,Cardiovasc | Calcium Channel |
Lercanidipine hydrochloride (Corifeo) is a calcium channel blocker of the dihydropyridine class. | |||
T6374 | Alfacalcidol | Bondiol,Etalpha,1-hydroxy Vitamin D3,1.alpha.-Hydroxyvitamin D3,1-hydroxycholecalciferol | Others |
Alfacalcidol (Etalpha) (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication. | |||
T24840 | STS-E412 | STSE412 | |
STS-E412 is a selective activator of the tissue-protective EPOR/CD131 receptor. | |||
T6467 | Cardioxane | ADR-529 Hydrochloride,ICRF-187 hydrochloride,ADR-529,Dexrazoxane HCl,Cardioxane hydrochloride,ICRF-187 | Topoisomerase |
Cardioxane (ADR-529) is a cardio-protective drug. | |||
T21252 | DHMB | 2,3-Dihydroxy-4-Methoxybenzaldehyde | Others |
DHMB (2,3-Dihydroxy-4-Methoxybenzaldehyde) exerts protective effects on intestinal epithelial cells. DHMB exhibits anti-inflammatory and antifungal capacity. | |||
T4510 | Polaprezinc | Zinc L-carnosine | Others |
Polaprezinc is an bioavailable chelate comprised of zinc and L-carnosine, known for its gastrointestinal protective properties, as well as its anti-ulcer, antioxidant, and anti-inflammatory effects. | |||
T0259 | Chromocarb | Chromone-2-carboxylic acid,Chromocarbe | Others |
Chromocarb (Chromone-2-carboxylic acid) is a vascular protective agent used to treat venous disorders and microvascular affections. | |||
T24821 | Spizofurone | Espizofurona,AG-629 | Others |
Spizofurone (Espizofurona) has antiulcer activity, protective effect on the gastric mucosa of rats, and can increase alkaline secretion in isolated bullfrog duodenal mucosa. | |||
T31675 | Esaprazole | C/63 | Others |
Esaprazole (C/63) has a dose - dependent cellular protective effect on the human gastric mucosa. | |||
T20109 | Cystamine dihydrochloride | Others | |
Cystamine dihydrochloride is a radiation-protective agent. It also protects against carbon tetrachloride liver damage. | |||
T26647 | AR420626 | AR 420626,AR-420626 | Others |
AR420626 is a selective fatty acid 3 receptor (FA3R) agonist and provides protective effects against salsolionl (SALS), which was totally blocked by beta-hydroxy butyrate (BHB), a selective FA3R antagonist. | |||
T1812 | KX1-004 | KX1 004,KX1004 | Src |
KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK. | |||
T8982 | RH01687 | Others | |
RH01687 is a potent β-cell protector , exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress. | |||
T3102 | NS-1619 | Apoptosis , Potassium Channel | |
NS1619 have cardio-protective effects after ischemia-reperfusion injury. | |||
T65816 | Prolyl-4-hydroxylase Inhibitor 11 | Others | |
Prolyl-4-hydroxylase Inhibitor 11, a novel proline 4-hydroxylase inhibitor, shows protective effects against oxidative stress and Cu(II) toxicity in Chlorella vulgaris. | |||
T20843 | Aplodan | Nergize,Creatinolfosfate,creatinol-O-phosphate,Creatinolfosfate, Creatinol Phosphate | Others |
Aplodan (creatinol-O-phosphate) exhibits antiischemic and antiarrhythmic capacity and protective action on the cell membrane. Aplodan can be used in research on the ischemic heart or ischemic heart disease with persisten... | |||
T14061 | EMCS | 6-Maleimidohexanoic acid N-hydroxysuccinimide ester | Others |
EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) is a heterobifunctional crosslinking agent, which is a compound for the preparation of hapten conjugate and enzyme immune conjugate, and an effective protective ... | |||
T28655 | Sabeluzole | R 58735,R58735,R-58735 | Microtubule Associated |
Sabeluzole (R-58735) has antiepileptic and cognitive enhancing effects, inhibits neurotoxin-induced tau expression and cell death.Sabeluzole is protective against chlordiazepoxide-induced habituation disorders and may be... | |||
T21470L | Davunetide acetate | Davunetide acetate(211439-12-2 Free base) | Beta Amyloid , Microtubule Associated |
Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing peptide and inhibits Aβ aggregation and Aβ-induced neurotoxicit... | |||
T15049 | Daltroban | BM-13505,SKF 96148 | PPAR |
Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells. | |||
T72059 | S1R agonist 2 | Sigma receptor , ROS , NMDAR | |
S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity. | |||
T14569 | BI8626 | E1/E2/E3 Enzyme | |
BI8626 is a ubiquitin ligase HUWE1 inhibitor with protective effects against spontaneous desiccation syndrome in NOD/ShiLtj mice.BI8626 inhibits intracellular cholesterol and decreases the expression of phosphorylated ZA... | |||
T67717L | Questiomycin A derivatives 18 TFA | ||
Questiomycin A derivatives 18 TFA is A Questiomycin A derivative with antibacterial and anticancer activity and inhibition of the expression of the cell-protective ER chaperone protein GRP78. | |||
T5672 | 2,4-Diaminophenoxyethanol HCl | Others | |
Isophorone (3,5,5-trimethyl-2-cyclohexen-1-one), a monoterpene, and the structurally related 1,8-cineole and camphor, have demonstrated a protective effect against cancer, biological activity against a variety of microor... | |||
T28248 | Ono-3307 mesylate | Ono-3307,Ono3307,Ono 3307 | Protease |
Ono-3307 mesylate is a protease inhibitor with inhibitory effects on a variety of proteases.Ono-3307 mesylate has significant protective effects against liver injury in rats and inhibits the deposition of radiofibrillar ... | |||
T9180 | LUF6096 | CF-602 | Adenosine Receptor |
LUF6096 (CF-602) is a potent allosteric enhancer of the adenosine A3 receptor, exhibiting the capability to enhance agonist binding allosterically while demonstrating low orthosteric affinity across adenosine receptors. ... | |||
T16724 | Razuprotafib | AKB-9778 | Phosphatase , Others |
Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ß (HPTPß) inhibitor (IC50: 50 nM). Razuprotafib is effective for the activation of Tie-2 and is protective against acute kidney injury. | |||
T67908 | ThioLox | Lipoxygenase | |
ThioLox is a competitive 15-lipoxygenase-1 (15-LOX-1) inhibitor with IC50 value of 12 μM. ThioLox shows anti-inflammatory and neuroprotective properties. It has anti-inflammatory and neuroprotective effects, and has a st... | |||
T77245 | Mannan | Endogenous Metabolite | |
Mannan is isolated from algae, mushrooms, yeast and higher plants and acts as an immunomodulator.Mannan inhibits the pro-inflammatory activity of hepatic macrophages (M1 lineage) with protective effects against many live... | |||
T13416 | ZX-29 | ALK | |
ZX-29 is a potent and selective inhibitor of ALK(IC50 of 2.1 nM, 1.3 nM and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively), and also induces protective autophagy and has antitumor effect. | |||
T36619 | Aligeron | Prostaglandin Receptor | |
Aligeron is a non-selective prostaglandin (PG) antagonist that inhibits PGF2α- and PGE2-induced decreases in blood pressure in cats, and can be used to inhibit PGF2α-induced diarrhea in mice and PGE2-induced paw edema in... | |||
T13396 | Zinc Protoporphyrin | Zinc Protoporphyrin-9,ZnPP,Zn(II)-protoporphyrin IX | Apoptosis , Reactive Oxygen Species , Endogenous Metabolite |
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive inhibitor of heme oxygenase-1 (HO-1) and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2, and has anti-can... | |||
T16031 | McMMAF | Maleimidocaproyl monomethylauristatin F | Microtubule Associated |
McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC linker), which is ready to conjugate to antibody or other prote... | |||
T37436 | C12-Ceramide | N-Laurylsphingosine,C12 Ceramide (d18:1/12:0),N-Lauroyl-D-erythro-sphingosine | |
C12-Ceramide (C12 Ceramide (d18:1/12:0)), a ceramide present in the protective membranes surrounding umbilical cord blood vessels in infants born to women with pre-eclampsia, can be used to assess the level of ASM activi... | |||
T20681 | Estramustine | NSC-89201,NSC 89201,LEO 275,LEO275,NSC89201,LEO-275 | Microtubule Associated |
Estramustine (LEO-275) is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties. Estramustine is selectively taken... | |||
T11518L | GW274150 | NOS | |
GW274150 is an orally active, selective and potent dual inhibitor of NADPH-dependent human nitric oxide synthase (iNOS) (Kd=40 nM) and rat inducible nitric oxide synthase (iNOS).GW274150 has a low activity against endoth... | |||
T50032 | 5-(2-furyl)-N-propylisoxazole-3-carboxamide | Others | |
5-(2-furyl)-N-propylisoxazole-3-carboxamide is a compound used as a molecular structural unit and is thought to be a modulator of NMDA receptors, and has been shown to be protective against glutamate-induced excitotoxici... | |||
T1880 | P7C3 | Others | |
The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, be... | |||
T9948 | NecroX-7 | LC-280126,LC28-0126,LC28 0126 | NADPH-oxidase |
NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing ... | |||
T21967 | MEG hemisulfate | Mercaptoethylguanidine hemisulfate | NOS |
MEG hemisulfate (Mercaptoethylguanidine hemisulfate) acts as a highly potent and selective suppressor of inducible NO synthase (iNOS), demonstrating EC50 values of 11.5 μM for iNOS, 110 μM for ecNOS, and 60 μM for bNOS i... | |||
T23709 | AlphaSYN-IN-NAB2 | alphaSYN inhibitor NAB2,alphaSYNINNAB2,alphaSYN-IN-NAB2,NAB2,alphaSYN inhibitor-NAB2 | |
alphaSYN-IN-NAB2, a neuron-protective agent, is a protein encoded by the NAB2 gene. NAB2 effectively and selectively protects a variety of cells from alpha-SYN toxicity. NAB2 promotes endosomal transport dependent on E3 ... | |||
T34467 | S 75 | S75,S-75 | |
S 75 is a compound with radiation protective action. | |||
T13902 | SSF-109 | Huanjunzuo | Others |
SSF-109 is a broad-spectrum fungicide, has protective activity against plant disease. | |||
T4451L | Estramustine phosphate | LS 299,NSC 89199,NSC-89199,LS-299,LS299 | |
Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8158 | Tilianin | Others | |
Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L. | |||
T2808 | Bilobalide | (-)-Bilobalide | Apoptosis , Endogenous Metabolite , Autophagy |
Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations. | |||
T6S1525 | 3,4-Dicaffeoylquinic acid | Isochlorogenic acid B | Apoptosis , Antioxidant , Influenza Virus , Endogenous Metabolite |
3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity. | |||
T2S1200 | Sinapine | Antioxidant , P-gp , AChE | |
1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant and radio-protective activities. | |||
T3392 | Sinapine thiocyanate | P-gp , AChE | |
Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds. It is the choline ester of Sinapic Acid (S486800). It is also a phenolic-chloine conjugates, acting as anti-o... | |||
TN6774 | Emodin 6-O-β-D-glucoside | Glucoemodin | Others |
Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside ... | |||
T6S1917 | Schisandrol B | Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B | P450 , Reactive Oxygen Species , Autophagy |
1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a... | |||
T5145 | Oxytocin acetate | Oxytocic hormone acetate,α-Hypophamine acetate,Oxytocin acetate (50-56-6 free base) | Oxytocin Receptor |
Oxytocin acetate (α-Hypophamine acetate) is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor. | |||
T80778 | Weak Hepatoprotective agent-1 | ||
Compound 11, labeled as a weak Hepatoprotective agent-1, is a naturally occurring substance extracted from the fruits of Arctium lappa L. It demonstrates modest hepatoprotective effects when applied at a concentration of... | |||
TQ0226 | Jionoside B1 | Others | |
Jionoside B1 has immunosuppressive activity and shows the hepato-protective activity in the H2O2 induced liver injury experiments. | |||
T3S1534 | Secoxyloganin | Anti-infection | |
Secoxyloganin possesses a hepato-protective effect. Secoxyloganin possesses antibacterial activity. Secoxyloganin has cytotoxic activity against UACC-62 cell line.Secoxyloganin possesses the perfect protective effect on ... | |||
TN4973 | Sculponeatin O | Others | |
Sculponeatin O may have protective effects on the lipid peroxidation-damaged live cells. | |||
T5760 | (-)-Salutaridine | SINOACUTINE | Others |
(-)-Salutaridine is a natural product isolated from Stephania epigaea Lo.Sinoacutine has protective effects against hydrogen peroxide-induced cell injury. | |||
TN4972 | Sculponeatin N | Others | |
Sculponeatin N may have protective effects on the lipid peroxidation-damaged live cells. | |||
T3S0289 | Araloside X | Calcium Channel | |
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane perox... | |||
T5S1632 | Barlerin | 8-O-Acetylshanzhiside methyl ester,ND01 | VEGFR , TNF , NF-κB , Akt , Caspase |
Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e... | |||
TN1494 | Cimicifugoside H-1 | Others | |
Cimicifugoside H1 shows the protective function to cerebral neuron during cerebral ischemia. | |||
T5665 | Geraniol | Others , Endogenous Metabolite , Antifungal | |
geraniol provides a potent protective effect against cardiac dysfunction induced by diabetes. This ameliorative effect could be attributed to its suppression of oxidative stress. | |||
T6S2246 | Alisol B 23-acetate | Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B | Others |
1. Alisol B 23-acetate (Alisol B Acetate) produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotiv... | |||
TN4661 | Nodosin | IL Receptor , Autophagy | |
Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transp... | |||
TN1058 | Pelargonidin chloride | NOS , Reactive Oxygen Species , Nrf2 , NO Synthase | |
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway. | |||
T6S1367 | Procyanidin B2 | Proanthocyanidin B2 | Reactive Oxygen Species , NOD |
Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression ... | |||
T4S0217 | HOMOPLANTAGININ | TNF , NF-κB | |
Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and shows potent inhibitory activities against influenza. | |||
TN1274 | 4-Allylcatechol | 4-Allylpyrocatechol,Hydroxychavicol | Others |
4-Allylcatechol (Hydroxychavicol) has antioxidant activity, it has protective activity against the photosensitization-induced damage to lipids and proteins of rat liver mitochondria, which attributes to its free radical ... | |||
T8200 | Ginkgolide K | AMPK , Autophagy | |
Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity. | |||
T4S1983 | Periplogenin | 5-beta-Hydroxydigitoxigenin,Desoxostrophanthidin | Others |
1. Periplogenin (Desoxostrophanthidin) plays protective roles against thyrotoxicosis and associated cardiovascular problems, are mediated through its direct antithyroidal and/or LPO inhibiting properties. | |||
TN1650 | Friedelin | P450 , NOS , Caspase , Prostaglandin Receptor | |
Friedelin possesses antioxidant, gastroprotective, anti-diarrhoeal, liver protective, anti-inflammatory, analgesic and antipyretic activities. | |||
T1391 | 4-Methylumbelliferone | Hymecromone,4-MU | Others |
4-Methylumbelliferone (Hymecromone) is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the determination of NITR... | |||
T36818 | Questiomycin A | GPR , Antibacterial | |
Questiomycin A is an antibiotic produced in crème fraiche with antibacterial and anticancer activities. Questiomycin A suppresses expression of GRP78, a cell-protective ER chaperone protein. | |||
T3405 | [6]-Gingerol | 6-Gingerol,gingerol,(S)-(+)-[6]Gingerol | Apoptosis , AMPK |
[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for Yous tumors in the pancreas, ovaries, breast tissue, the bowel, among other tissues. | |||
T6S1294 | Nicotiflorin | Nictoflorin,Kaempferol-3-O-Rutinoside,Nicotifloroside | Others |
1. Nicotiflorin (Kaempferol-3-O-Rutinoside) has potential therapeutic effects on cerebral ischemic illness. 2. Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative s... | |||
T5751 | Tigogenin | Others | |
Tigogenin is one of steroidal sapogenins which is widely used for synthesizing steroid drugs. It might have protective effect on bone and be helpful in preventing the development of osteoporosis. | |||
T5S0045 | Isofraxidin | 6,8-Dimethoxyumbelliferone,Phytodolor | MMP , ERK , p38 MAPK , TLR , COX |
1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the prote... | |||
TN7134 | Magnoloside B | Glucosidase | |
Magnoloside B, a phenylethanol glycoside from the fruit of Magnolia officinalis, is an α-glucosidase inhibitor with protective effects against free radical-induced oxidative damage and can be used in cancer research. | |||
T4454 | Traumatic Acid | Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,Trans-2-Dodecenedioic Acid | Antioxidant |
Traumatic Acid (Dodec-2-Enedioic Acid) is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective callus. | |||
T19866 | Indican | NSC-87517,3-Indoxyl-beta-D-glucopyranoside,NSC 87517,NSC87517,Indoxyl-β-D-glucoside | OAT , MRP |
Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver. | |||
T4829 | 3-Hydroxyphenylacetic acid | Others , Endogenous Metabolite | |
3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxyphenylacetate 3-monooxygenase [EC 1.14.13.3] in the pathway tyro... | |||
TN1238 | 3,4-O-Isopropylidene-shikimic acid | 3,4-O-Isopropylidene shikimic acid | NOS , NO Synthase |
3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by tri... | |||
TMS2180 | Zeaxanthin | Anchovyxanthin,All-Trans-Zeaxanthin | Antioxidant , Endogenous Metabolite |
1. Lutein and Zeaxanthin (All-Trans-Zeaxanthin) in neural tissue may have biological effects that include antioxidation, anti-inflammation, and structural actions. 2. Lutein and Zeaxanthin may be protective against eye d... | |||
T19792 | 1,3,7-Trimethyluric acid | Others | |
1,3,7-Trimethyluric acid is a purine alkaloid that occurs as a minor metabolite of caffeine in humans. As an antioxidant, it has shown an ability to scavenge hydroxyl radicals as well as protective potential against lipi... | |||
T5S0285 | Cistanoside A | Others | |
1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respirat... | |||
T2S0690 | Ecliptasaponin A | Echinocystic acid-3-o-glucoside | Others |
1. Ecliptasaponin A (Echinocystic acid-3-o-glucoside) has protective effects against the pulmonary fibrosis induced by bleomycin via reducing the oxidative stress, lung tissue inflammation, and the subsequent epithelial-... | |||
TN2173 | Salvianolic acid D | (R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid | Others |
Salvianolic acid D ((R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid) and notoginseng triterpenes can promote EA-hy926 and expression of protein with protective effec... | |||
T2S0500 | Ilexsaponin A | Ilexsaponin A1 | Others |
1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. | |||
T25253 | Cinnamtannin B-1 | Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358 | Antioxidant , COX |
Cinnamtannin B-1 (LDN 0022358) is an A-type proanthocyanidin contained in several plant species such as Vaccinium vitis-idaea, Laurus nobilis L., Cinnamomum zeylanicum, and Lindera umbellata. It is a potent antioxidant a... | |||
T3920 | Pseudoginsenoside F11 | Ginsenoside A1 | Others , Endogenous Metabolite |
Pseudoginsenoside F11 (Ginsenoside A1) is a component of Panax quinquefolium (American ginseng) which main pharmacological activities are positive inotropic effect on isolated heart function, good therapeutic effect on m... | |||
TN1921 | Meloside A | Isovitexin 2''-O-glucoside,Isovitexin 2''-O-β-D-glucoside | Others |
Meloside A (Isovitexin 2''-O-β-D-glucoside) is a phenylpropanoid extracted from barley. Meloside A exhibits antioxidant and protective properties against excess UV-B radiation and has been linked to resistance to pathoge... | |||
T3S1319 | (+)-Magnoflorine | Escholin,Magnoflorine,Thalictrin,Escholine | Others , Antifungal |
(+)-Magnoflorine (Thalictrin) has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. Magnoflorine and Sinomenine have protective effects, are mediated by some mech... | |||
T4953 | Neotuberostemonine | NOS | |
Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruit... | |||
TWS1563 | Incensole | Others | |
1. Incensole has a protective or stimulating effect on β-cells of the rat pancreas, it also can increase the insulin secretion, which evidenced by a significant increase both in body weight and in liver glycogen. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-01246 | GDF-15 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t... | |||
TMPY-02971 | CLEC10A Protein, Human, Recombinant (hFc) | Human | HEK293 |
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is ... | |||
TMPY-01147 | R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) | Human | HEK293 |
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... | |||
TMPY-03197 | R-Spondin 1/RSPO1 Protein, Mouse, Recombinant (His) | Mouse | CHO |
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... | |||
TMPY-03626 | R-Spondin 1/RSPO1 Protein, Human, Recombinant | Human | CHO |
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r... | |||
TMPY-04340 | Mucin-1/MUC1 Protein, Human, Recombinant | Human | HEK293 |
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr... | |||
TMPY-02005 | Mucin-1/MUC1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr... | |||
TMPJ-01172 | IL-17 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid seque... | |||
TMPY-00638 | Interferon alpha B/IFNA8 Protein, Human, Recombinant (His) | Human | HEK293 |
Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites... | |||
TMPY-01884 | MMP-8 Protein, Human, Recombinant | Human | HEK293 |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPY-04578 | Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) | Human | Yeast |
IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, par... | |||
TMPY-02515 | Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interferon alpha-7(IFNA7) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a c... | |||
TMPY-03523 | ANGPTL4 Protein, Human, Recombinant (His) | Human | HEK293 |
ANGPTL4, also known as ANGPTL2, is a protein with hypoxia-induced expression in endothelial cells. It contains 1 fibrinogen C-terminal domain and is expressed at high levels in the placenta, heart, liver, muscle, pancrea... | |||
TMPY-00835 | IGFBP-3 Protein, Human, Recombinant (His) | Human | HEK293 |
The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory... | |||
TMPY-01870 | IL-9 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Interleukin 9, also known as IL-9, is a cytokine (cell signaling molecule) belonging to the group of interleukins. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates... | |||
TMPY-03490 | IL-22 Protein, Human, Recombinant | Human | E. coli |
IL22 is a member of a group of cytokines called the IL-1 family of IL-1 superfamily (including IL-19, IL-2, IL-24, and IL-26), a class of potent mediators of cellular inflammatory responses. It shares the use of IL-1R2 i... | |||
TMPY-01356 | S100A8 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
S100A8 is a member of the S100 protein family containing 2EF-hand calcium-binding motifs. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation.... | |||
TMPY-05750 | Human coronavirus (HCoV-OC43) Spike S1 Protein (His) | HCoV-OC43 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05670 | Human coronavirus (HCoV-NL63) Spike S1 Protein (His) | HCoV-NL63 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05674 | Human coronavirus (HCoV-NL63) Spike Protein (S1+S2 ECD, His) | HCoV-NL63 | Baculovirus-Insect Cells |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05675 | Human coronavirus (HCoV-229E) Spike Protein (S1+S2 ECD, His) | HCoV-229E | Baculovirus-Insect Cells |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-03574 | MERS-CoV Spike/S1 Protein (aa 1-725, His) | MERS-CoV | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05671 | Human coronavirus (HCoV-229E) Spike S1 Protein (His) | HCoV-229E | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-03512 | MERS-CoV Spike/S2 Protein (aa 726-1296, His) | MERS-CoV | Baculovirus-Insect Cells |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05676 | Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) Spike Protein (S1+S2 ECD, His) | HCoV-HKU1 | Baculovirus-Insect Cells |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-02429 | Human coronavirus HKU1 (isolate N1) (HCoV-HKU1) Spike S1 Protein (His) | HCoV-HKU1 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-00402 | MERS-CoV Spike/RBD Protein fragment (aa 367-606, His) | MERS-CoV | Baculovirus-Insect Cells |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-03661 | MERS-CoV Spike Protein (S1+S2 ECD, aa 1-1297, His) | MERS-CoV | Baculovirus-Insect Cells |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-06013 | Human coronavirus (HCoV-OC43) Spike S2 Protein (His) | HCoV-OC43 | Baculovirus-Insect Cells |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05677 | Human coronavirus (HCoV-OC43) Spike Protein (S1+S2 ECD, His) | HCoV-OC43 | Baculovirus-Insect Cells |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPY-05679 | SARS-CoV-2 Spike RBD Protein (hFc) | SARS-CoV-2 | HEK293 |
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4;... | |||
TMPH-01706 | Mucin-16/MUC16 Protein, Human, Recombinant (His) | Human | HEK293 |
Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. | |||
TMPK-00564 | TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of... | |||
TMPH-03108 | GPX5 Protein, Pig, Recombinant (E. coli, His & Myc) | Sus scrofa (Pig) | E. coli |
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxi... | |||
TMPH-03109 | GPX5 Protein, Pig, Recombinant (His & Myc) | Sus scrofa (Pig) | Yeast |
May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxi... | |||
TMPH-03275 | Cytoglobin Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity. | |||
TMPH-01296 | GPX5 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective syste... | |||
TMPK-00442 | SARS-COV-2 (Omicron B.1.1.529) Spike S Trimer Protein (His & Avi), Biotinylated | SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00441 | SARS-COV-2 Spike S Trimer Protein (His & Avi), Biotinylated | SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00440 | SARS-COV-2 Spike S1 Protein (His & Avi), Biotinylated | SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00432 | SARS-COV-2 Spike S1 Protein (hFc & Avi) | SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00437 | SARS-COV-2 Spike RBD Protein (His & Avi) | SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00912 | SARS Spike RBD Protein (His & Avi), Biotinylated | SARS | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00910 | SARS Spike S1 Protein (His & Avi) | SARS | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00909 | SARS Spike S1 Protein (hFc & Avi), Biotinylated | SARS | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00438 | SARS-COV-2 Spike S Trimer Protein (His & Avi) | SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00443 | SARS-COV-2 (Omicron B.1.1.529) Spike S1 Protein (His & Avi), Biotinylated | SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00911 | SARS Spike RBD Protein (His & Avi) | SARS | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00444 | SARS-COV-2 Spike S1 NTD Protein (His & Flag) | SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
TMPK-00434 | SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated | SARS-CoV-2 | HEK293 |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k... | |||
------------------------ More ------------------------ |
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L6710 | Anti-Inflammatory Traditional Chinese Medicine Compound Library | 1260 compounds | |
A collection of 1260 TCM monomers with anti-inflammatory activity or targeting molecular therapeutic targets in inflammation, a powerful tool for drug discovery and mechanism study; | |||
L6120 | Flavonoid Natural Product Library | 477 compounds | |
A unique collection of 477 flavonoids can be used for high throughput and high content screening; | |||
L7110 | Anti-Hypertension Compound Library | 719 compounds | |
719 hypertension-related small molecules for high-throughput and high-content screening. |