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Results for "

protac linker 5

" in TargetMol Product Catalog

Inhibitors & Agonists
105
PROTAC Products
104
ADC/ADC Related
7

NH2-PEG3-C1-Boc

T16666189808-70-6

NH2-PEG3-C1-Boc is a PEG-based PROTAC linker that can be used for the synthesis of PROTAC molecules.

PROTAC Linker

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5-Ethynyl-2'-deoxyuridine

T1734161135-33-9

5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine used to monitor de novo DNA synthesis through click chemistry and serves as an alkyl chain-based PROTAC linker for synthesizing PROTACs.

PROTAC Linker

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Cited

Thalidomide-5-OH

2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione

T929164567-60-8

Thalidomide-5-OH (2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione) is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.

Apoptosis Autophagy Ligand for E3 Ligase

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Hydroxy-PEG5-Boc

T15534850090-09-4

Hydroxy-PEG6-Boc, a PEG-based PROTAC linker, is utilized in PROTAC synthesis [1].

PROTAC Linker

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N-Boc-PEG5-bromide

T162181392499-32-9

N-Boc-PEG5-bromide is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and serves as a PROTAC linker based on PEG and Alkyl/ether.

ADC Linker PROTAC Linker

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Biotin-C5-amino-C5-amino

T1754889889-51-0

Biotin-C5-amino-C5-amino is an alkyl chain-based PROTAC linker utilized in PROTAC synthesis.

PROTAC Linker

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Boc-NH-PEG4-CH2CH2NH2

T17679811442-84-9

Boc-NH-PEG4-CH2CH2NH2 is a cleavable 5-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

ADC Linker PROTAC Linker

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Cbz-NH-PEG5-CH2COOH

T177241449390-66-2

Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker used in PROTAC synthesis.

PROTAC Linker

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Mal-PEG5-Boc

Mal-PEG5-T-Butyl Ester, Mal-PEG5-COOtBu

T182952250216-91-0

Mal-PEG5-Boc (Mal-PEG5-COOtBu) is a PEG-based PROTAC linker. Mal-PEG5-Boc can be used in the synthesis of PROTACs.

PROTAC Linker

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Propargyl-PEG5-Ms

Propargyl-PEG6-Ms

T185881036204-62-2

Propargyl-PEG5-Ms (Propargyl-PEG6-Ms) is a PEG-based PROTAC linker. Propargyl-PEG5-Ms can be used in the synthesis of PROTACs.

PROTAC Linker

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Amino-PEG5-amine

T1424372236-26-1

Amino-PEG5-amine, a PEG-based linker containing 5 units, is utilized in PROTAC synthesis.

Others PROTAC Linker

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7-10 days

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Azido-PEG5-alcohol

T1445686770-68-5

Azido-PEG5-alcohol, a non-cleavable 5 unit polyethylene glycol (PEG) ADC linker, finds application in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, it serves as a PEG-based PROTAC linker for the synthesis of PROTACs[2].

ADC Linker PROTAC Linker

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Bis-PEG5-acid

PROTAC Linker 36

T14642439114-13-3

Bis-PEG5-acid (PROTAC Linker 36) is a polyethylene glycol (PEG) linker used in the synthesis of CP5V, a PROTAC that selectively degrades Cdc20[1].

Others PROTAC Linker

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7-10 days

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Bis-propargyl-PEG6

T14659400775-35-1

Bis-propargyl-PEG6 is a polyethylene glycol (PEG) derivative commonly employed as a PEG-based PROTAC linker during the synthesis of PROTACs. Its application includes the generation of polymer-linked multimers of guanosine-3', 5'-cyclic monophosphates[1].

Others PROTAC Linker

5 days

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DBCO-PEG5-NHS ester

T150752144395-59-3

DBCO-PEG5-NHS ester is a PROTAC linker belonging to the PEG and Alkyl/ether classes for the synthesis of a range of PROTAC molecules.

ADC Linker PROTAC Linker

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HOOCCH2O-PEG4-CH2COOH

T1549977855-75-5

HOOCCH2O-PEG4-CH2COOH (compound 5), is a symmetric polyethylene glycol (PEG) linker. It is primarily utilized in the synthesis of the initial Homo-PROTAC[1] compound.

Others PROTAC Linker

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7-10 days

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Methyltetrazine-PEG5-NHS ester

T160601802907-92-1

Methyltetrazine-PEG5-NHS ester is a PROTAC linker belonging to the group of PEGs and is used for the synthesis of PROTAC molecules.

PROTAC Linker

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NH2-PEG5-OH

T1631434188-11-9

NH2-PEG5-OH is a polyethylene glycol (PEG)-based PROTAC linker, utilized for the synthesis of PROTACs[1]. It is a 5-unit PEG ADC linker that is non-cleavable, and employed in the synthesis of antibody-drug conjugates (ADCs)[2].

ADC Linker PROTAC Linker

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7-10 days

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Propargyl-PEG1-acid

T1658355683-37-9

Propargyl-PEG1-acid, a PEG-based PROTAC linker, enables the synthesis of BTK-CRBN PROTACs, specifically Ibrutinib-based PROTAC 4 and PROTAC 5. At a concentration of 10 μM, PROTAC 5 facilitates the degradation of BTK and induces the degradation of CSK, LYN, and LAT2[1].

Others PROTAC Linker

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7-10 days

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5-endo-BCN-pentanoic acid

T173402364591-80-8

5-endo-BCN-pentanoic acid, an alkyl chain-based PROTAC linker, facilitates the synthesis of PROTACs[1].

Others PROTAC Linker

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Azido-PEG5-azide

T17515356046-26-9

Azido-PEG5-azide, a PEG-based PROTAC linker, is used in PROTAC synthesis.

PROTAC Linker

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Pomalidomide-PEG3-C2-NH2

E3 ligase Ligand-Linker Conjugates 30, Cereblon Ligand-Linker Conjugates 5

T178832093416-31-8

Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide based cereblon ligand and 3-unit PEG linker.

E3 Ligase Ligand-Linker Conjugate PROTAC Linker

$195

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cIAP1 Ligand-Linker Conjugates 5

E3 ligase Ligand-Linker Conjugates 39

T178932113688-20-1

cIAP1 Ligand-Linker Conjugates 5 is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 5, is specifically designed for the development of SNIPERs[1].

E3 Ligase Ligand-Linker Conjugate Others

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(S,R,S)-AHPC-PEG4-N3

VHL Ligand-Linker Conjugates 5, VH032-PEG4-N3, E3 ligase Ligand-Linker Conjugates 4, (S,R,S)-AHPC-PEG4-Azide

T179211797406-81-5

(S,R,S)-AHPC-PEG4-N3 (VHL Ligand-Linker Conjugates 5) is a synthesized ligand-linker for E3 ligase-based systems, comprising the (S,R,S)-AHPC VHL ligand and a 4-unit PEG linker, commonly used in PROTAC technology.

E3 Ligase Ligand-Linker Conjugate PROTAC Linker

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