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Search Results for " metabolite "

Targets

1341

Compounds

1494

Natural Products

9

Recombinant Proteins

9

Libraries

Cat No. Product Name Synonyms Targets
T21059 Ticagrelor metabolite M5 Ticagrelor metabolite M5,,T437700,AR-C133913XX P2Y Receptor
Ticagrelor metabolite M5 (T437700) is a metabolite of Ticagrelor, the first reversible oral antagonist of P2Y12 receptor. Compared to Clopidogrel, Ticagrelor has faster and more consistent inhibition on ADP-receptors. Ti...
T16045 Methotrexate metabolite DAMPA Antifolate , Drug Metabolite
Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic agent and immunosuppressant.
T10738 Abemaciclib metabolite M20 CDK4/6-IN-4,LSN3106726 CDK
Abemaciclib metabolite M20 (CDK4/6-IN-4) is an active metabolite of Abemaciclib. Abemaciclib metabolite M20 is a selective CDK4/6 inhibitor and can be used for researches on the treatment of cancer.
T13133 Tetrabenazine Metabolite (-)-β-Dihydrotetrabenazine,(-)-β-HTBZ Monoamine Transporter
Tetrabenazine Metabolite ((-)-β-HTBZ), a vesicles monoamine transporter 2 (VMAT2) inhibitor, is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite has a high affinity for VMAT2 with a Ki of 13.4 nM. Tetraben...
T10814 Cinacalcet metabolite M4 Rarechem AL BW 1078 Calcium Channel
Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor.
T5401 GSK2983559 active metabolite GSK2983559,RIPK2 inhibitor 1,RIPK2-IN-1 RIP kinase
GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.
T12309 Omeprazole metabolite Omeprazole sulfone Omeprazole sulphone,Omeprazole sulfone Others
Omeprazole metabolite Omeprazole sulfone can inhibit proton pump.
T36661 Iloperidone metabolite P95 Iloperidone metabolite P95
Iloperidone metabolite P95 is a metabolite of the atypical antipsychotic iloperidone . It binds to the serotonin (5-HT) receptor subtype 5-HT2A and α1-, α2B-, and α2C-adrenergic receptors with mean Ki values of 7.08, 21....
T37181 Avanafil metabolite M4 Avanafil metabolite M4
Avanafil metabolite M4 is a major active metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil . Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites avanaf...
T36662 Imidafenacin Metabolite M4 Imidafenacin Metabolite M4
Imidafenacin metabolite M4 is a metabolite of the muscarinic acetylcholine receptor antagonist imidafenacin.1It is formed from imidafenacin by the cytochrome P450 (CYP) isoform CYP3A4. 1.Kanayama, N., Kanari, C., Masuda,...
T11445 GNF179 (Metabolite) GNF179 Metabolite Others
GNF179 Metabolite, the derivative of GNF179—an optimized 8,8-dimethyl IP analog—demonstrates significant potency (4.8 nM against the multidrug-resistant W2 strain) alongside in vitro metabolic stability and in vivo oral ...
T12229 Niraparib metabolite M1 M1 metabolite of niraparib,Niraparib carboxylic acid metabolite M1 Others
Niraparib metabolite M1 is niraparib metabolite, niraparib is a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.
T23983 Deutetrabenazine metabolite M4 SD-1018,Deuterated monohydroxy tetrabenazine,D6-tetrabenazine metabolite M4
Deutetrabenazine metabolite M4 is believed to be related to its effect as a reversible depletion of monoamines from nerve terminals. The major circulating metabolites of Deutetrabenazine, are reversible inhibitors of VM...
T37638 Tofacitinib metabolite-1
Tofacitinib metabolite-1, a derivative of Tofacitinib, which is a JAK inhibitor, is employed in studies focused on the pharmacokinetics and metabolism of tofacitinib[1][2].
T37180 Avanafil metabolite M16
Avanafil metabolite M16 is a major inactive metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil . Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites ava...
T39345 Lopinavir Metabolite M-1
Lopinavir Metabolite M-1, an active metabolite derived from Lopinavir, effectively inhibits the HIV protease enzyme with a Ki value of 0.7 pM. Additionally, in vitro studies have revealed notable antiviral properties ass...
T68375 KD026-metabolite
KD026-metabolite, is a metabolite of KD-026. KD026, also known as SLx-4090, is a microsomal triglyceride transfer protein (MTTP) inhibitor potentially for the treatment of type 2 diabetes.
T70178 Sonidegib metabolite M25
Sonidegib metabolite M25 is a smoothened (SMO) antagonist.
T11893L Lurasidone metabolite 14326 hydrochloride Lurasidone metabolite 14326 hydrochloride (186204-33-1 free base) Others
Lurasidone metabolite 14326 hydrochloride, an active metabolite of the atypical antipsychotic Lurasidone, maintains its significant function in pharmacological efficacy.
T20723 LGE-899 Sonidegib metabolite M48,LGE 899 Drug Metabolite
LGE-899 (Sonidegib metabolite M48) is a main metabolite of Sonidegib which is an inhibitor of the hedgehog pathway. The Tmax of LGE-899(60 h) is much longer than Sonidegib.
T12735 Ritonavir metabolite Desthiazolylmethyloxycarbonyl Ritonavir Others
Ritonavir metabolite is a Ritonavir metabolite, which is a inhibitor of HIV protease.
T37645 Dasatinib metabolite M6
Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib, a potent and orally active inhibitor of both Bcr-Abl and Src family tyrosine kinases[1].
T10220 Abemaciclib metabolite M2 Abemaciclib Metabolites M2 CDK
Abemaciclib Metabolites M2 is a metabolite of abemaciclib, acts as a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anti-cancer activity.
T23950 Dacomitinib metabolite M2 Dacomitinib cysteine conjugate,UNII-SOA52D3NLL
Dacomitinib metabolite M2 is also known as Dacomitinib cysteine conjugate. Dacomitinib inhibits both the wild-type (WT) EGFR and EGFR T790M.
T35815 Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans. Vildagliptin carboxylic acid metabolite has an IC50 value of 477 μM for DPP-4 in hum...
T11893 Lurasidone metabolite 14326 Others
Lurasidone metabolite 14326, an active metabolite of the atypical antipsychotic Lurasidone, functions effectively in the body.
T13525 Abiraterone metabolite 1 3β-OH-5α-Abi Others
Abiraterone Metabolite 1, a 5β-reduced derivative of abiraterone, acts by inhibiting CYP17A1, thereby blocking androgen synthesis and extending survival in prostate cancer patients.
T19407 Lurasidone Metabolite 14326 D8 Others
Lurasidone Metabolite 14326 D8 is the deuterium labeled Lurasidone Metabolite 14326.
T2687 Omeprazole sulfide Omeprazole metabolite Omeprazole sulfide,Ufiprazole Proton pump , Drug Metabolite
Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor.
T71932 MAM2201 N-pentanoic acid metabolite
MAM2201 N-pentanoic acid metabolite is a potential phase 1 metabolite of MAM2201 -- a cannabinoid receptor agonist.
T19406 Lurasidone Metabolite 14283 D8 Others
Lurasidone Metabolite 14283 D8 is the deuterium labeled Lurasidone Metabolite 14283.
T33659 Nicardipine pyridine metabolite II
Nicardipine pyridine metabolite II is a biaoctive chemical.
T10358L AR-13324 M1 metabolite Others
AR-13324 M1 metabolite is a hydrolysis metabolite of AR-13324 mesylate.
T12689 Ramelteon metabolite M-II Others
Ramelteon metabolite M-II is the major Ramelteon metabolite(human melatonin receptors (MT1 or MT2) with IC50s of 208 pM, 1470 pM). Ramelteon is an agonist of selective melatonin.
T13760 Lurasidone Metabolite 14283 hydrochloride Others
Lurasidone Metabolite 14283 hydrochloride is a major active metabolite of Lurasidone.
T12211 Netupitant metabolite Monohydroxy Netupitant Monohydroxy Netupitant Others
Monohydroxy Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite.
T12212 Netupitant metabolite N-desmethyl Netupitant N-desmethyl Netupitant Others
N-desmethyl Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite.
T73909 Abemaciclib metabolite M18 LSN3106729 Ligands for Target Protein for PROTAC
Abemaciclib metabolite M18 (LSN3106729) is a potent cyclin-dependent kinase (CDK) inhibitor with antitumor properties. It has been incorporated alongside a cereblon (CRBN) ligand to develop a proteolysis-targeting chimer...
T11641 N-Desmethyl imatinib Imatinib metabolite N-Desmethyl imatinib,Norimatinib Bcr-Abl , PDGFR , c-Kit , Drug Metabolite
N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.
T11637 Iloperidone metabolite Hydroxy Iloperidone P88,Hydroxy Iloperidone Others
Iloperidone metabolite Hydroxy Iloperidone is an atypical antipsychotic. It is a metabolite of Iloperidone.
T19175 Acetaminophen metabolite 3-hydroxy-acetaminophen 3-Hydroxyacetaminophen Others
3-hydroxy-acetaminophen is a metabolite of Acetaminophen. Acetaminophen is a pain medicine.
T12213 Netupitant metabolite Netupitant N-oxide Netupitant N-oxide Others
Netupitant N-oxide is a highly selective antagonist of NK1 receptor, is Netupitant metabolite.
T10686 Carvedilol metabolite 4-Hydroxyphenyl Carvedilol 4-Hydroxyphenyl Carvedilol,4-Hydroxycarvedilol Others
4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol. Carvedilol is a beta-blocker/alpha-1 blocker.
T11114 Duloxetine metabolite Para-Naphthol Duloxetine Para-Naphthol duloxetine Others
Para-Naphthol Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI),is a metabolite of Duloxetine.
T83676 Tianeptine Metabolite MC5 sodium
Tianeptine metabolite MC5, an active derivative of the atypical antidepressant tianeptine produced through β-oxidation, exhibits selective G protein activation in bioluminescence resonance energy transfer (BRET) assays. ...
T32000 GSK-1071306 Pazopanib metabolite M27
GSK-1071306 is a bio-active chemical.
T19667 R-138727 Prasugrel active metabolite
R-138727 is a novel P2Y12 receptor inhibitor.
T20465 Ketopioglitazone Keto pioglitazone,Pioglitazone metabolite M3
Ketopioglitazone is an active metabolite of pioglitazone.
T11987 Mebeverine alcohol Mebeverine metabolite Mebeverine alcohol Others
Mebeverine alcohol is a metabolite of Mebeverine.
T11986 Mebeverine acid Mebeverine metabolite Mebeverine acid Drug Metabolite
Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine and can be used as a marker of oral exposure to Mebeverine.

Compounds

Ticagrelor metabolite M5
T21059
Synonym: Ticagrelor metabolite M5,,T437700,AR-C133913XX
Target: P2Y Receptor
Methotrexate metabolite
T16045
Synonym: DAMPA
Target: Antifolate, Drug Metabolite
Abemaciclib metabolite M20
T10738
Synonym: CDK4/6-IN-4,LSN3106726
Target: CDK
Tetrabenazine Metabolite
T13133
Synonym: (-)-β-Dihydrotetrabenazine,(-)-β-HTBZ
Target: Monoamine Transporter
Cinacalcet metabolite M4
T10814
Synonym: Rarechem AL BW 1078
Target: Calcium Channel
GSK2983559 active metabolite
T5401
Synonym: GSK2983559,RIPK2 inhibitor 1,RIPK2-IN-1
Target: RIP kinase
Omeprazole metabolite Omeprazole sulfone
T12309
Synonym: Omeprazole sulphone,Omeprazole sulfone
Target: Others
Iloperidone metabolite P95
T36661
Synonym: Iloperidone metabolite P95
Target:
Avanafil metabolite M4
T37181
Synonym: Avanafil metabolite M4
Target:
Imidafenacin Metabolite M4
T36662
Synonym: Imidafenacin Metabolite M4
Target:
GNF179 (Metabolite)
T11445
Synonym: GNF179 Metabolite
Target: Others
Niraparib metabolite M1
T12229
Synonym: M1 metabolite of niraparib,Niraparib carboxylic acid metabolite M1
Target: Others
Deutetrabenazine metabolite M4
T23983
Synonym: SD-1018,Deuterated monohydroxy tetrabenazine,D6-tetrabenazine metabolite M4
Target:
Tofacitinib metabolite-1
T37638
Synonym:
Target:
Avanafil metabolite M16
T37180
Synonym:
Target:
Lopinavir Metabolite M-1
T39345
Synonym:
Target:
KD026-metabolite
T68375
Synonym:
Target:
Sonidegib metabolite M25
T70178
Synonym:
Target:
Lurasidone metabolite 14326 hydrochloride
T11893L
Synonym: Lurasidone metabolite 14326 hydrochloride (186204-33-1 free base)
Target: Others
LGE-899
T20723
Synonym: Sonidegib metabolite M48,LGE 899
Target: Drug Metabolite
Ritonavir metabolite
T12735
Synonym: Desthiazolylmethyloxycarbonyl Ritonavir
Target: Others
Dasatinib metabolite M6
T37645
Synonym:
Target:
Abemaciclib metabolite M2
T10220
Synonym: Abemaciclib Metabolites M2
Target: CDK
Dacomitinib metabolite M2
T23950
Synonym: Dacomitinib cysteine conjugate,UNII-SOA52D3NLL
Target:
Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)
T35815
Synonym:
Target:
Lurasidone metabolite 14326
T11893
Synonym:
Target: Others
Abiraterone metabolite 1
T13525
Synonym: 3β-OH-5α-Abi
Target: Others
Lurasidone Metabolite 14326 D8
T19407
Synonym:
Target: Others
Omeprazole sulfide
T2687
Synonym: Omeprazole metabolite Omeprazole sulfide,Ufiprazole
Target: Proton pump, Drug Metabolite
MAM2201 N-pentanoic acid metabolite
T71932
Synonym:
Target:
Lurasidone Metabolite 14283 D8
T19406
Synonym:
Target: Others
Nicardipine pyridine metabolite II
T33659
Synonym:
Target:
AR-13324 M1 metabolite
T10358L
Synonym:
Target: Others
Ramelteon metabolite M-II
T12689
Synonym:
Target: Others
Lurasidone Metabolite 14283 hydrochloride
T13760
Synonym:
Target: Others
Netupitant metabolite Monohydroxy Netupitant
T12211
Synonym: Monohydroxy Netupitant
Target: Others
Netupitant metabolite N-desmethyl Netupitant
T12212
Synonym: N-desmethyl Netupitant
Target: Others
Abemaciclib metabolite M18
T73909
Synonym: LSN3106729
Target: Ligands for Target Protein for PROTAC
N-Desmethyl imatinib
T11641
Synonym: Imatinib metabolite N-Desmethyl imatinib,Norimatinib
Target: Bcr-Abl, PDGFR, c-Kit, Drug Metabolite
Iloperidone metabolite Hydroxy Iloperidone
T11637
Synonym: P88,Hydroxy Iloperidone
Target: Others
Acetaminophen metabolite 3-hydroxy-acetaminophen
T19175
Synonym: 3-Hydroxyacetaminophen
Target: Others
Netupitant metabolite Netupitant N-oxide
T12213
Synonym: Netupitant N-oxide
Target: Others
Carvedilol metabolite 4-Hydroxyphenyl Carvedilol
T10686
Synonym: 4-Hydroxyphenyl Carvedilol,4-Hydroxycarvedilol
Target: Others
Duloxetine metabolite Para-Naphthol Duloxetine
T11114
Synonym: Para-Naphthol duloxetine
Target: Others
Tianeptine Metabolite MC5 sodium
T83676
Synonym:
Target:
GSK-1071306
T32000
Synonym: Pazopanib metabolite M27
Target:
R-138727
T19667
Synonym: Prasugrel active metabolite
Target:
Ketopioglitazone
T20465
Synonym: Keto pioglitazone,Pioglitazone metabolite M3
Target:
Mebeverine alcohol
T11987
Synonym: Mebeverine metabolite Mebeverine alcohol
Target: Others
Mebeverine acid
T11986
Synonym: Mebeverine metabolite Mebeverine acid
Target: Drug Metabolite
1 2 3 4 5 ... 27
Cat No. Product Name Synonyms Targets
T16338 Norgestimate metabolite Norelgestromin 17-Deacetyl norgestimate,17-Deacylnorgestimate Drug Metabolite
Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive patches, where it is combined with the estrogen ethinyl es...
Fr13756 Isonicotinic acid Endogenous Metabolite , Drug Metabolite
Isonicotinic acid is a metabolite of Isoniazid.Isonicotinic acid is a useful isomer of nicotinic acid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the biotransformation also to be catalyzed by cyt...
T13539 Allopurinol riboside Others , Endogenous Metabolite , Parasite , Drug Metabolite
Allopurinol riboside is a metabolite of allopurinol with potency against parasites. Allopurinol riboside competitively inhibits the action of purine nucleoside phosphorylase on inosine with a Ki of 277 μM.
T10815 Cinnamoylglycine Endogenous Metabolite
Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in humans. It is used as a potential urinary biomarker.
T12287 Octadecanedioic acid Endogenous Metabolite
Octadecanedioic acid is an endogenous metabolite, is a long-chain dicarboxylic acid.
TN1740 Homoeriodictyol 5-HT Receptor , transporter , Sodium Channel , Drug Metabolite
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotoni...
TN1490 Chrysoeriol ERK , p38 MAPK , Akt
Chrysoeriol has antioxidant, antiinflammatory, antitumor, antimicrobial, antiviral, and free radical scavenging activities, it also shows selective bronchodilator effect.
T4799 Indole Others , Endogenous Metabolite
Indole is an aromatic heterocyclic organic compound. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. It can be produced by bacteria as a d...
T15720 Lathosterol Endogenous Metabolite
Lathosterol, a molecule akin to cholesterol, serves as a biomarker for the body's total cholesterol synthesis, as indicated by its serum concentration.
T8153 Glycohyodeoxycholic acid Others , Endogenous Metabolite
glycohyodeoxycholic acid is a major metabolite of the secondary bile acid hyodeoxycholic acid in humans.
T10021 1-Methylxanthine Endogenous Metabolite
1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.
T13719 Hexadecanal Palmitaldehyde Endogenous Metabolite
Hexadecanal (Palmitaldehyde) is a free fatty aldehyde present in animals.
T8272 Trierucin Others , Endogenous Metabolite
Trierucin is a trierucic acid triglyceride isolated from the seed oil.
T0586 Lactose Others , Endogenous Metabolite
Lactose is a disaccharide derived from galactose and glucose that is found in milk.
T0647 Tryptamine Dehydrogenase , 5-HT Receptor , Endogenous Metabolite , TRP/TRPV Channel
Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It is found in trace amounts in the brains of mammals and is r...
T8165 Erythrodiol Endogenous Metabolite , ABC
Erythrodiol, an olive oil component, promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein.
T20446 Creosol Endogenous Metabolite
Creosol is an agent of Antioxidant and Antibacterial.
T0069 Uracil Others , Endogenous Metabolite
Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synt...
T5665 Geraniol Others , Endogenous Metabolite , Antifungal
geraniol provides a potent protective effect against cardiac dysfunction induced by diabetes. This ameliorative effect could be attributed to its suppression of oxidative stress.
T37508 Meconin Endogenous Metabolite
Meconin, a noscapine metabolite, is a urinary detection marker for illicit opiate misuse. This product is intended for use as a forensic standard.
T8068 O-Toluic acid Others
o-Toluic acid, also 2-methylbenzoic acid, is an aromatic carboxylic acid. It is a human xenobiotic metabolite.
T19792 1,3,7-Trimethyluric acid Others
1,3,7-Trimethyluric acid is a purine alkaloid that occurs as a minor metabolite of caffeine in humans. As an antioxidant, it has shown an ability to scavenge hydroxyl radicals as well as protective potential against lipi...
T36790 (Ethoxymethyl)benzene Endogenous Metabolite
(Ethoxymethyl)benzene is an endogenous metabolite.
TN6833 Octanal Endogenous Metabolite , Antibacterial
octanal is a natural product with antioxidant and antimicrobial activities.
T7602 Theaflavin Influenza Virus , Endogenous Metabolite
Theaflavin is a polyphenolic flavonoid that has been found in black tea and has diverse biological activities, including antioxidant, anticancer, anti-inflammatory, and antiviral properties
T8086 Decyl aldehyde Others , Endogenous Metabolite
Decyl aldehyde is a ten-carbon aldehyde that is a substrate for bacterial luciferase.
T5352 GLYCODEOXYCHOLIC ACID Others , Endogenous Metabolite
Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells.
T8031 Terephthalic acid Others , Endogenous Metabolite
Terephthalic acid, an isomer of the three phthalic acids, serves as a precursor to the polyester PET, which is utilized in manufacturing plastic bottles and clothing.
T4776 Glycerol Glycerin Endogenous Metabolite
Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol...
T12095 Monomethyl fumarate GPR , Drug Metabolite
Monomethyl fumarate is a potent agonist of GPR109A .
T4809 Pyrimidine Metadiazine Others , Endogenous Metabolite
Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ...
TN6752 Dimethyl sulfone Endogenous Metabolite
Dimethyl sulfone exists in all living organisms, ranging from bacteria to humans. It derives from dietary sources, from intestinal bacterial metabolism and from human endogenous methanethiol metabolism. Dimethyl sulfone ...
T37298 Spinacine Endogenous Metabolite
Spinacine has been isolated from spinach and the roots of Panax ginseng. This conformationally constrained amino acid is a structural element in certain biologically active compounds as glucagon antagonists and angiotens...
T37501 Ethoxyacetic acid Endogenous Metabolite
Ethoxyacetic acid is an endogenous metabolite of ethylene glycol monoethyl ether acetate.
T13581 Biotin sulfone Endogenous Metabolite
Biotin sulfone is isolated as a natural metabolite of biotin.
T5565 Undecanedioic acid Others , Endogenous Metabolite
Undecanedioic acid has been found in parts of human aortas with advanced atherosclerotic lesions associated with intercellular matrix macromolecules and specifically with elastin.
T7331 Ursocholic acid Endogenous Metabolite
Ursocholic acid, a bile acid found predominantly in bile of mammals.
T5228 Nicotinuric acid Others , Endogenous Metabolite
Nicotinuric acid is an acyl glycine which is normally minor metabolites of fatty acids. Acyl glycines are produced through the action of glycine N-acyltransferase.
T2724 Caryophyllene oxide Others , Endogenous Metabolite
Caryophyllene oxide is isolated from Aegle marmelos, with anti-inflammatory activity.
T19418 Methionine sulfoxide Endogenous Metabolite
Methionine sulfoxide, an oxidation product of methionine formed through interaction with reactive oxygen species, serves as a biomarker for oxidative stress in vivo.
T5812 Zinc Phytate Others
Zinc Phytate, present in food, plays a crucial role in human nutrient absorption.
T2228 Adipic acid Others , Endogenous Metabolite
Adipic acid is a precursor for the production of nylon.
T8049 Pentadecanoic acid Others , Endogenous Metabolite
Pentadecylic acid is a saturated fatty acid.
T4794 Glutaric acid Endogenous Metabolite
Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan
T5737 Euphol Others , Lipase , Endogenous Metabolite
Euphol, an alcohol tetracyclic triterpene, has a wide range of pharmacological properties and is considered to have anti-inflammatory action.
T4761 Pyridoxal hydrochloride Others , Endogenous Metabolite
The 4-carboxyaldehyde form of vitamin B6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.
T5985 Glycolic acid Tyrosinase , Endogenous Metabolite
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare products
TQ0284 Hydroxyphenyllactic acid Endogenous Metabolite , Antifungal
Hydroxyphenyllactic acid is an antifungal metabolite, fungi such as Lactobacillus sp. SK007.
T4883 Creatine Methylguanidoacetic acid Endogenous Metabolite
Creatine (Methylguanidoacetic acid) is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine. Creati...
T4729 Phosphonoacetic acid Endogenous Metabolite
Phosphonoacetate, also known as fosfonet or phosphonacetic acid, belongs to the class of organic compounds known as organic phosphonic acids.Within the cell, phosphonoacetate is primarily located in the cytoplasm. Phosph...
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Natural Products

Norgestimate metabolite Norelgestromin
T16338
Synonym: 17-Deacetyl norgestimate,17-Deacylnorgestimate
Target: Drug Metabolite
Isonicotinic acid
Fr13756
Synonym:
Target: Endogenous Metabolite, Drug Metabolite
Allopurinol riboside
T13539
Synonym:
Target: Others, Endogenous Metabolite, Parasite, Drug Metabolite
Cinnamoylglycine
T10815
Synonym:
Target: Endogenous Metabolite
Octadecanedioic acid
T12287
Synonym:
Target: Endogenous Metabolite
Homoeriodictyol
TN1740
Synonym:
Target: 5-HT Receptor, transporter, Sodium Channel, Drug Metabolite
Chrysoeriol
TN1490
Synonym:
Target: ERK, p38 MAPK, Akt
Indole
T4799
Synonym:
Target: Others, Endogenous Metabolite
Lathosterol
T15720
Synonym:
Target: Endogenous Metabolite
glycohyodeoxycholic acid
T8153
Synonym:
Target: Others, Endogenous Metabolite
1-Methylxanthine
T10021
Synonym:
Target: Endogenous Metabolite
Hexadecanal
T13719
Synonym: Palmitaldehyde
Target: Endogenous Metabolite
Trierucin
T8272
Synonym:
Target: Others, Endogenous Metabolite
Lactose
T0586
Synonym:
Target: Others, Endogenous Metabolite
Tryptamine
T0647
Synonym:
Target: Dehydrogenase, 5-HT Receptor, Endogenous Metabolite, TRP/TRPV Channel
Erythrodiol
T8165
Synonym:
Target: Endogenous Metabolite, ABC
Creosol
T20446
Synonym:
Target: Endogenous Metabolite
Uracil
T0069
Synonym:
Target: Others, Endogenous Metabolite
Geraniol
T5665
Synonym:
Target: Others, Endogenous Metabolite, Antifungal
Meconin
T37508
Synonym:
Target: Endogenous Metabolite
o-Toluic acid
T8068
Synonym:
Target: Others
1,3,7-Trimethyluric acid
T19792
Synonym:
Target: Others
(Ethoxymethyl)benzene
T36790
Synonym:
Target: Endogenous Metabolite
octanal
TN6833
Synonym:
Target: Endogenous Metabolite, Antibacterial
Theaflavin
T7602
Synonym:
Target: Influenza Virus, Endogenous Metabolite
Decyl aldehyde
T8086
Synonym:
Target: Others, Endogenous Metabolite
GLYCODEOXYCHOLIC ACID
T5352
Synonym:
Target: Others, Endogenous Metabolite
Terephthalic acid
T8031
Synonym:
Target: Others, Endogenous Metabolite
Glycerol
T4776
Synonym: Glycerin
Target: Endogenous Metabolite
Monomethyl fumarate
T12095
Synonym:
Target: GPR, Drug Metabolite
Pyrimidine
T4809
Synonym: Metadiazine
Target: Others, Endogenous Metabolite
Dimethyl sulfone
TN6752
Synonym:
Target: Endogenous Metabolite
Spinacine
T37298
Synonym:
Target: Endogenous Metabolite
Ethoxyacetic acid
T37501
Synonym:
Target: Endogenous Metabolite
Biotin sulfone
T13581
Synonym:
Target: Endogenous Metabolite
Undecanedioic acid
T5565
Synonym:
Target: Others, Endogenous Metabolite
Ursocholic acid
T7331
Synonym:
Target: Endogenous Metabolite
Nicotinuric acid
T5228
Synonym:
Target: Others, Endogenous Metabolite
Caryophyllene oxide
T2724
Synonym:
Target: Others, Endogenous Metabolite
Methionine sulfoxide
T19418
Synonym:
Target: Endogenous Metabolite
Zinc Phytate
T5812
Synonym:
Target: Others
Adipic acid
T2228
Synonym:
Target: Others, Endogenous Metabolite
Pentadecanoic acid
T8049
Synonym:
Target: Others, Endogenous Metabolite
Glutaric acid
T4794
Synonym:
Target: Endogenous Metabolite
euphol
T5737
Synonym:
Target: Others, Lipase, Endogenous Metabolite
Pyridoxal hydrochloride
T4761
Synonym:
Target: Others, Endogenous Metabolite
Glycolic acid
T5985
Synonym:
Target: Tyrosinase, Endogenous Metabolite
Hydroxyphenyllactic acid
TQ0284
Synonym:
Target: Endogenous Metabolite, Antifungal
Creatine
T4883
Synonym: Methylguanidoacetic acid
Target: Endogenous Metabolite
Phosphonoacetic acid
T4729
Synonym:
Target: Endogenous Metabolite

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-00776 Griffithsin Protein, Griffithsia sp., Recombinant (X31S, His & Myc) Griffithsia sp. Baculovirus
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
TMPY-03414 ABHD10 Protein, Human, Recombinant (aa 53-306, His) Human Baculovirus-Insect Cells
Mycophenolic acid (MPA), the active metabolite of the immunosuppressant mycophenolate mofetil (MMF), is primarily metabolized by glucuronidation to a phenolic glucuronide (MPAG) and an acyl glucuronide (AcMPAG). It is...
TMPY-00320 APOA1BP Protein, Human, Recombinant (His) Human HEK293
APOA1BP, now renamed NAXE, encodes an epimerase essential in the cellular metabolite repair for NADHX and NADPHX. The enzyme catalyzes the epimerization of NAD(P)HX, thereby avoiding the accumulation of toxic metabolites...
TMPH-02352 Influenza A H3N2 (strain A/Kitakyushu/159/1993) Nucleoprotein/NP Protein (His) H3N2 E. coli
Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cystei...
TMPH-01438 HFE Protein, Human, Recombinant (His & Myc) Human E. coli
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the thre...
TMPH-02221 TRIM24 Protein, Human, Recombinant (His & SUMO) Human E. coli
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, a...
TMPH-01439 Human herpesvirus 1 (HHV-1) (strain 17) Envelope glycoprotein C (His & Myc) HHV-1 E. coli
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the thre...
TMPY-02420 HEMK2 Protein, Human, Recombinant (His) Human E. coli
N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes an N(6)-adenine-specific DNA methyltransferase. It belongs to t...
TMPH-00772 Leghemoglobin C2 Protein, Glycine max, Recombinant (His) Glycine max E. coli
Serine/threonine-protein kinase that activates necroptosis and apoptosis, two parallel forms of cell death. Necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members, is triggere...
Cat No. Product Name
L2500 Human Endogenous Metabolite Library

508 compounds
A collection of 508 selected human endogenous metabolites for high throughput and high content screening.
L5800 Drug Metabolite/Impurity Library

200 compounds
A unique collection of 200 drug isomers/metabolites for high throughput screening (HTS) and high content screening (HCS);
L2530 Mouse Metabolite Compound Library

224 compounds
A unique collection of 224 mouse metabolites, which can be used for HTS and HCS;
L2540 Gut Microbial Metabolite Library

614 compounds
A unique collection of 614 gut microbial metabolites which can be used for HTS and HCS;
L6001 Mini Fungal Metabolite Natural Product Screening Library

Inquiry
L2570 Human Metabolite Library

4532 compounds
A unique collection of 4532 human metabolites for high-throughput, high-content screening.
L2501 Human Endogenous Metabolite Compound Library Plus

1300 compounds
A unique collection of 1300 endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening.
L5510 Drug-induced Liver Injury (DILI) Compound Library

1040 compounds
A unique collection of 1040 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening;
L2560 Metabolism Compound Library

2350 compounds
A unique collection of 2350 metabolic pathway-related bioactive small molecule compounds for high-throughput, high-content screening.
TargetMol