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luteinizing hormone releasing hormone

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    46
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    27
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Luteinizing Hormone Releasing Hormone (LH-RH), salmon
LH-RH, salmon
TP111286073-88-3
Luteinizing Hormone Releasing Hormone (LH-RH), synthesized in the hypothalamus, is a pituitary hormone that plays a crucial role in controlling reproductive function.
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Nafarelin
T2072476932-56-4
Nafarelin is a gonadotropin-releasing hormone (GnRH) agonist. Nafarelin increases the release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) by the anterior pituitary leading to an increase of estrogen progesterone.
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    Teverelix
    T28954151272-78-5
    Teverelix is a water-soluble antagonist of luteinizing hormone-releasing hormone (LHRH).
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    Kisspeptin-54 (human) (trifluoroacetate salt)
    T35794
    Kisspeptin-54 is a peptide ligand of the orphan G protein-coupled receptor GPR54 (Kis = 1.81 and 1.45 nM for rat and human receptors, respectively).1 It is a 54 amino acid peptide encoded by the metastasis suppressor gene KISS-1. Kisspeptin-54 induces calcium mobilization in CHO-K1 cells expressing rat and human receptors (EC50s = 1.39 and 5.47 nM, respectively). It also induces arachidonic acid release in CHO cells expressing rat and human GPR54 in a concentration-dependent manner. Kisspeptin-54 (10-1,000 nM) inhibits insulin secretion from isolated mouse pancreatic β-cells in the presence of 2.8 mM, but not 11.1 mM, glucose.2 Kisspeptin-54 (1-5 nmol, i.c.v.) increases serum levels of luteinizing hormone (LH) and follicular stimulating hormone (FSH) in mice, an effect which is reversed by the gonadotropin releasing hormone (GNRH) antagonist acycline.3References1. Kotani, M., Detheux, M., Vandenbogaerde, A.L., et al. The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J. Biol. Chem. 276(37), 34631-34636 (2001).2. Vikman, J., and Ahrén, B. Inhibitory effect of kisspeptins on insulin secretion from isolated mouse islets. Diabetes Obes. Metab. 11(Suppl 4), 197-201 (2009).3. Gottsch, M.L., Cunningham, M.J., Smith, J.T., et al. A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Endocrinology 145(9), 4073-4077 (2004). Kisspeptin-54 is a peptide ligand of the orphan G protein-coupled receptor GPR54 (Kis = 1.81 and 1.45 nM for rat and human receptors, respectively).1 It is a 54 amino acid peptide encoded by the metastasis suppressor gene KISS-1. Kisspeptin-54 induces calcium mobilization in CHO-K1 cells expressing rat and human receptors (EC50s = 1.39 and 5.47 nM, respectively). It also induces arachidonic acid release in CHO cells expressing rat and human GPR54 in a concentration-dependent manner. Kisspeptin-54 (10-1,000 nM) inhibits insulin secretion from isolated mouse pancreatic β-cells in the presence of 2.8 mM, but not 11.1 mM, glucose.2 Kisspeptin-54 (1-5 nmol, i.c.v.) increases serum levels of luteinizing hormone (LH) and follicular stimulating hormone (FSH) in mice, an effect which is reversed by the gonadotropin releasing hormone (GNRH) antagonist acycline.3 References1. Kotani, M., Detheux, M., Vandenbogaerde, A.L., et al. The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J. Biol. Chem. 276(37), 34631-34636 (2001).2. Vikman, J., and Ahrén, B. Inhibitory effect of kisspeptins on insulin secretion from isolated mouse islets. Diabetes Obes. Metab. 11(Suppl 4), 197-201 (2009).3. Gottsch, M.L., Cunningham, M.J., Smith, J.T., et al. A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Endocrinology 145(9), 4073-4077 (2004).
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    Gonadorelin Acetate (33515-09-2 free base)
    Luteinizing Hormone Releasing Hormone (LH-RH), Luteinizing Hormone Releasing Hormone (LH-RH), human, Gonadorelin Acetate
    T501571447-49-9
    Gonadorelin Acetate (33515-09-2 free base) (Luteinizing Hormone Releasing Hormone (LH-RH)) is hypothalamic neuropeptide which plays a key role in the control of reproductive functions.
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    Cetrorelix diacetate
    SB-075 diacetate, NS-75A diacetate
    T5520L130143-01-0
    Cetrorelix diacetate (NS-75A) is is a gonadotropin-releasing hormone antagonist. It works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
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    TargetMol | Inhibitor Sale
    Ganirelix
    T75991124904-93-4
    Ganirelix is a selective and competitive antagonist of gonadotropin-releasing hormone (GnRH), effectively inhibiting endogenous GnRH from inducing the release of luteinizing hormone (LH) and follicle-stimulating hormone [1].
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    LH-RH II (chicken)
    T7632291097-16-4
    LH-RH II (chicken), a structural variant of mammalian luteinizing hormone-releasing hormone (LHRH) found in the hypothalamus of the domestic hen, exists as one of two forms of LHRH that enhance gonadotropin release in domestic chickens [1] [2].
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    GnRH Associated Peptide (25-53), human
    T76323106061-19-2
    Gonadotropin-Releasing Hormone-Associated Peptide (GAP) (25-53), Human, also known as hGAP-25-53, is a fragment of the human gonadotropin-releasing hormone-associated peptide that serves as an immunogen for producing antiseras such as MC-1, MC-2, and MC-3. This peptide is connected to the luteinizing hormone-releasing hormone (LH-RH) sequence through a 3 amino acid processing site [1].
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    GnRH Associated Peptide (1-24), human
    T76324148943-65-1
    Gonadotropin-Releasing Hormone-Associated Peptide (GAP) (1-24), human, also known as hGAP-1-24, is the 1-24 fragment of the human GAP, which is connected to the luteinizing hormone-releasing hormone (LH-RH) through a 3 amino acid processing site [1].
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    [D-Lys6]-LH-RH
    T7634852671-12-2
    [D-Lys6]-LH-RH, a Luteinizing-hormone-releasing hormone (LHRH) analogue, serves as a GnRH receptor agonist [1].
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    [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
    T7635068059-94-9
    [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH, a luteinizing hormone-releasing hormone (LHRH) analogue, acts as a gonadotropin-releasing hormone (GnRH) receptor antagonist [1].
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    LH-RH (7-10)
    T7635338482-71-2
    LH-RH (7-10), a tetrapeptide, constitutes a principal degradation product of luteinizing-hormone releasing hormone (LHRH) through the action of the pituitary and hypothalamus. This compound is synthesized in macrophages, as well as type I-like and type II pneumocytes [3].
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    Onvitrelin ucalontide
    T765581174415-90-7
    Onvitrelin ucalontide ([Phor18-LHRH (338613)]) is a luteinizing hormone-releasing hormone (LHRH) analogue with antineoplastic properties, characterized by the peptide sequence KFAKFAKKFAKFAKKFAKQHWSYGLRPG. It is effective in inhibiting breast, ovarian, and prostate cancer xenografts in mouse models [1] [2].
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    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
    T76602150646-45-0
    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a corticotropin-releasing factor (CRF) antagonist that counteracts the inhibitory effects of IL-1a on luteinizing hormone (LH) production [1].
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    (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH
    T766151926163-38-3
    (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH, an analogue of luteinizing hormone-releasing hormone (LHRH), regulates reproductive processes by stimulating the secretion of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) [1].
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    (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
    T766161926163-39-4
    (D-Ser4, D-Ser(tBu)6, Azagly10)-LHRH, an analogue of luteinizing hormone-releasing hormone (LHRH), plays a pivotal role in reproductive regulation by promoting the secretion of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) [1].
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    (D-Trp6)-LHRH free acid
    T76617129418-54-8
    (D-Trp6)-LHRH free acid is a luteinizing hormone-releasing hormone (LHRH) agonist [1].
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    (D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH
    T766201426173-74-1
    (D-Tyr5, D-Ser(tBu)6, Azagly10)-LHRH, an analogue of luteinizing hormone-releasing hormone (LHRH), promotes the pituitary release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), playing a pivotal role in reproductive control [1].
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    LHRH
    T8011635263-73-1
    Luteinizing hormone-releasing hormone (LHRH) is a neuropeptide produced in the hypothalamus that plays a pivotal role in regulating reproduction and has applications in cancer research [1].
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    Human follicular gonadotropin releasing peptide
    hF-GRP
    T82162107873-08-5
    Human Follicular Gonadotropin Releasing Peptide (hF-GRP) is a hormonal peptide that, in vitro, can induce the secretion of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) [1] [2].
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    [D-Phe2,D-Ala6]-LH-RH
    Wy 18185
    T8349854784-44-0
    [D-Phe2,D-Ala6]-LH-RH is a potent luteinizing hormone-releasing hormone (LH-RH) antagonist, exhibiting significant activity against LH FSH-RH and possessing the ability to inhibit ovulation [1].
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    [D-Phe2,6, Pro3]-LH-RH
    T8349964789-67-9
    [D-Phe2,6, Pro3]-LH-RH is a potent antagonist of luteinizing hormone-releasing hormone (LHRH).
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    LH-RH, salmon acetate(86073-88-3 free base)
    Luteinizing Hormone Releasing Hormone (LH-RH), salmon acetate
    TP1112L
    LH-RH, salmon acetate(86073-88-3 free base) (Luteinizing Hormone Releasing Hormone (LH-RH), salmon acetate) is a pituitary Hormone synthesized in the hypothalamus and plays a crucial role in the control of reproductive function.
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