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Results for "

kcl

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    12
    TargetMol | Inhibitors_Agonists
  • Natural Products
    3
    TargetMol | Natural_Products
KCL-286
T785751952276-71-9In house
KCL-286 is an orally available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI).
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8-10weeks
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KCL-440
RS-57639, RS57639, RS 57639
T34413651029-09-3
RS 57639 is a bioactive chemical.
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β-NETA
T1419431059-54-8In house
β-NETA (α-NETA) is a stable, noncompetitive, slowly reversible choline acetyltransferase (ChAT) inhibitor with an IC50 of 9 μM and is a potent chemokine-like receptor-1 (CMKLR1) antagonist. β-NETA has anti-cancer activity[1][2]. β-NETA weakly inhibits cholinesterase (IC50=84 µM) and acetylcholinesterase (IC50=300 µM).
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7-10 days
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Lecozotan HCl
SRA-333, SRA333, SRA 333, Lecozotan hydrochloride
T27806433282-68-9In house
Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties. Chronic administration of Lecozotan HCl did not induce 5-HT(1A) receptor tolerance or desensitization in a behavioral model demonstrating 5-HT(1A) receptor function.
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6-8weeks
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Oxodipine
T6812390729-41-2In house
Oxodipine, a dihydropyridine-type calcium antagonist, inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventricular myocytes, Oxodipine reduced L-type Ca currents (I) with an IC of 0.24 μM, and against T-type Ca currents (I) with an IC of 0.41 μM. Oxodipine causes constipation in mice and gingival hyperplasia in dogs.
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TargetMol | Inhibitor Sale
Harmalol hydrochloride
Harmidol hydrochloride
TN17246028-07-5
Harmalol hydrochloride (Harmidol hydrochloride) is a β-carboline alkaloid that can be extracted from the seeds of Peganum harmala L. Harmalol hydrochloride is the major metabolite of Harmaline and significantly inhibits dioxin-mediated induction of CYP1A1 at both transcriptional and post-translational levels. Harmalol hydrochloride showed vasorelaxant activity in isolated rat thoracic aortic preparations preconstricted with phenylephrine or KCl. Harmalol hydrochloride has antioxidant activity.
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TargetMol | Inhibitor Sale
H100
T11528643727-55-3
H100 is a Cl- transport inhibitor, no effect against KCl cotransporter. It has partial effects against both the NaK2Cl cotransporter and the Band 3 anion exchanger.
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6-8 weeks
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GLUT4-IN-2
T616952454113-83-6
GLUT4-IN-2 is a specific GLUT4 inhibitor that inhibits GLUT1 and GLUT4.GLUT4-IN-2 has antitumor activity, induces apoptosis and cell cycle arrest, and can be used for cancer research.
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6-8 weeks
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SNJ-1945
T68547854402-59-8
SNJ-1945 is a calpain inhibitor with more favorable retinal penetration, high oral bioavailability, and long half-life. SNJ1945 rescued defective function in lissencephaly. SNJ-1945 protects SH-SY5Y cells against MPP(+) and rotenone. SNJ-1945 reduces murine retinal cell death in vitro and in vivo. SNJ-1945 has good aqueous solubility, can prevents the heart from KCl arrest-reperfusion injury associated with the impairment of total Ca(2+) handling by inhibiting the proteolysis of alpha-fodrin as a cardioplegia.
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8-10 weeks
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Macrophylline
TN448427841-97-0
Macrophylline A shows weak inhibitory action on KCl-induced contraction.
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Neoliensinine
TN8087
Neoliensinine, a benzylisoquinoline alkaloid, effectively inhibits the contraction of isolated mesenteric vascular smooth muscle (MVSM) induced by KCl (124 mM) with an IC50 value of 2.407 μM. It can be isolated from the embryos of the traditional Chinese medicine lotus seed (Nelumbo nucifera Gaertn.).
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α-Synuclein (67-78) (human)
TP26462243206-99-5
α-Synuclein (67-78) (human), a fragment spanning amino acids 67 to 78 of α-Synuclein, enhances network activity drive and inhibits the uptake of syt1L-ab induced by KCl [1].
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