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inactivator

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  • Inhibitors & Agonists
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Piperonylic acid
2H-1,3-benzodioxole-5-carboxylic acid
TN684894-53-1
Piperonylic acid (2H-1,3-benzodioxole-5-carboxylic acid) is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic acid selectively inactivate the CYP73A P450 subpopulation.
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Benzoylphenylalanine
NSC-118532, NSC118532, NSC 118532, N-Benzoyl-L-phenylalanine, L-BPA, LBPA, L BPA
T201892566-22-5
Benzoylphenylalanine (LBPA) can be used as a photoaffinity peptide inactivator.
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4-6 weeks
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Rhapontigenin
Protigenin
T3776500-65-2
Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. At higher concentrations, rhapontigenin inhibits the proliferation of HL-60R and HepG2 cancer cell lines (IC50: 48 μM).
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Linderane
T6S189413476-25-0
1. Linderane was characterized as a mechanism-based inactivator of CYP2C9.
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