Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Oxytocin Receptor
    (2)
  • Prostaglandin Receptor
    (2)
  • Akt
    (1)
  • Endogenous Metabolite
    (1)
  • GPCR19
    (1)
  • Influenza Virus
    (1)
  • Lipoxygenase
    (1)
  • MMP
    (1)
  • Proteasome
    (1)
  • Others
    (11)
Filter
Search Result
Results for "

hemorrhage

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    30
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    6
    TargetMol | Peptide_Products
  • Natural Products
    2
    TargetMol | Natural_Products
  • Recombinant Protein
    4
    TargetMol | Recombinant_Protein
  • Isotope Products
    2
    TargetMol | Isotope_Products
Carboprost tromethamine
T1486558551-69-2
Carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin F2α, effectively promotes uterine contractions and significantly reduces bleeding during and post-delivery.
  • Inquiry Price
Size
QTY
Carboprost
15-Methyl-PGF2α, 15(S)-15-Methyl Prostaglandin F2α
T2228535700-23-3
Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic analogue of PGF2α with oxytocic properties, commonly used to restore uterine tone.
  • Inquiry Price
4-6 weeks
Size
QTY
Aprotinin
Traskolan, Bovine Pancreatic Trypsin Inhibitor, Antilysin
T33599087-70-1
Aprotinin (Traskolan) is a broad-spectrum serine protease (BPTI) inhibitor that inhibits the activity of a number of different esterases and proteases. Aprotinin is an antifibrinolytic agent used to minimize hemorrhage during complex surgical procedures.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Hot
HLY78
4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine
T11571854847-61-3In house
HLY78 (4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine) targets the DIX domain of Axin, is an activator of the Wnt β-catenin signaling pathway and can enhance Axin-LRP6 binding to promote Wnt signaling.
  • Inquiry Price
Size
QTY
INT-777
S-EMCA
T11662L1199796-29-6In house
INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3 cAMP PKA signaling pathway after subarachnoid hemorrhage in rats.
  • Inquiry Price
8-10 weeks
Size
QTY
cm-352
T704701542205-83-3In house
CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.
  • Inquiry Price
10-14 weeks
Size
QTY
TargetMol | Inhibitor Sale
LJP-1586 HCl
LJP 1586, LJP-1586 hydrochloride, LJP-1586, LJP1586
T8857955037-42-0In house
LJP-1586 HCl, a highly selective inhibitor of vascular adhesion protein-1 (VAP-1), exhibits antiinflammation effect by reducing adhesion molecule expression and immune cell infiltration after intracerebral hemorrhage (ICH).
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
Fursultiamine
Judolor, Diteftin, Alinamin F
T4552804-30-8
Fursultiamine (Alinamin F) is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency.
  • Inquiry Price
Size
QTY
6-Methylnicotinamide
T665826960-22-1
6-Methylnicotinamide is a derivative of nicotinamide, an endogenous metabolite. 6-Methylnicotinamide is used to make co-crystals salts. In the acute phase of cerebral hemorrhage (ICH), a sudden increase in 6-Methylnicotinamide exacerbates neurological damage.6-Methylnicotinamide can be used to make co-crystals salts.6-Methylnicotinamide can be used to make co-crystals salts.
  • Inquiry Price
7-10 days
Size
QTY
TargetMol | Inhibitor Sale
ML351
T21902847163-28-4
ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).
  • Inquiry Price
Size
QTY
Carbetocin
T760137025-55-1
Carbetocin is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth.
  • Inquiry Price
Size
QTY
Edaravone-d5
MCI-186 D5
T111521228765-67-0
Edaravone, a novel and potent free radical scavenger, effectively prevents MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Its deuterium-labeled variant, Edaravone D5, retains the original compound's attributes while offering isotopic labeling benefits.
  • Inquiry Price
7-10 days
Size
QTY
ESI-05
NSC 116966
T152475184-64-5
ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
Collagenase, Type VII
9001-12-1
T201904
Collagenase, Type VII (EC 3.4.24.3), is an enzyme capable of inducing thalamic hemorrhage.
  • Inquiry Price
Size
QTY
Pgf2alpha 15-methyl ether
Prostaglandin F2alpha 15-methyl ether, AGN-191995, AGN191995, AGN 191995
T20296440834-96-6
Pgf2alpha 15-methyl ether is primarily used for the prevention of postpartum hemorrhage.
  • Inquiry Price
Size
QTY
(9R)-RO7185876
T2043582226077-86-5
(9R)-RO7185876 (Compound example 16) is a γ-secretase inhibitor. It reduces the secretion of Αβ42. This compound can be employed in the research of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, multi-infarct dementia, senile dementia, or Down syndrome.
  • Inquiry Price
10-14 weeks
Size
QTY
Desmethylanethol trithione
ADT-OH
T356018274-81-2
Desmethylanethol trithione (ADT-OH) is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. In the in vitro glucose-oxygen deprivation (OGD) model, Desmethylanethol trithione markedly attenuated tPA-enhanced Akt activation and VEGF expression in brain microvascular endothelial cells. Finally, Desmethylanethol trithione improved functional outcomes in mice subjected to MCAO and tPA infusion. H2S donors reduced tPA-induced cerebral hemorrhage by possibly inhibiting the Akt-VEGF-MMP9 cascade. Administration of H2S donors has potential as a novel modality to improve the safety of tPA following the stroke.
  • Inquiry Price
Size
QTY
Cimetidine sulfoxide
T3805854237-72-8
Cimetidine sulfoxide (Cimetidine sulphoxide), a metabolite of Cimetidine, is a histamine H2-receptor antagonist with potential applications in treating peptic ulcer disease and upper gastrointestinal hemorrhage [1].
    7-10 days
    Inquiry
    3-hydroxy-3-phenylpentanamide
    T50100131802-69-2
    3-hydroxy-3-phenylpentanamide is a chiral compound belonging to the class of beta-hydroxyamides. In neurology, it has been shown to have neuroprotective effects against ischemic brain injury and cerebral hemorrhage. In psychiatry, it has been studied as a potential treatment for anxiety, depression and addiction. In oncology, it has been shown to have antitumor activity by inducing apoptosis and inhibiting tumor growth.
    • Inquiry Price
    Size
    QTY
    piCRAC-1
    T616772418049-54-2
    piCRAC-1 is a powerful inhibitor of the photoinducible Ca2+ release-activated Ca2+ (CRAC) channel. It effectively alleviates thrombocytopenia and hemorrhage [1].
    • Inquiry Price
    6-8 weeks
    Size
    QTY
    LSKL, Inhibitor of Thrombospondin (TSP-1)
    T64709283609-79-0
    LSKL, INhibitor of Thrombospondin (TSP-1) is a TGF-β1 antagonist that inhibits the binding of TSP-1 to LAP and reduces renal interstitial fibrosis and liver fibrosis. LSKL can also inhibit subarachnoid fibrosis, prevent the occurrence of chronic hydrocephalus and improve long-term neurocognitive deficits after subarachnoid hemorrhage by inhibiting TSP-1-mediated TGF-β1 activity.
      7-10 days
      Inquiry
      Methazolamide-d6
      T701861795142-30-1
      Methazolamide-d6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg kg. It also inhibits production of reactive oxygen species (ROS) in a primary cortical neuron (PCN) cellular model of subarachnoid hemorrhage (SAH) and reduces cerebral edema in a mouse model of SAH.3 Methazolamide is larvicidal, with a 50% larvicidal concentration (LC50) value of 724 ppm, but has no activity when administered in the diet to adult A. aegypti. Formulations containing methazolamide have been used in the treatment of glaucoma.
      • Inquiry Price
      6-8 weeks
      Size
      QTY
      Tirilazad
      T73989110101-66-1
      Tirilazad, a nonglucocorticoid 21-aminosteroid, serves to inhibit lipid peroxidation. It mitigates the effects of trauma-induced brain or spinal cord injury, as well as damage resulting from stroke, ischemia, and reperfusion injury. Additionally, Tirilazad exhibits antiviral properties against nCoV and offers neuroprotection in cases of ischemic stroke. It is also utilized in subarachnoid hemorrhage research [1] [2] [3].
      • Inquiry Price
      7-10 days
      Size
      QTY
      Carbetocin acetate
      Carbetocin acetate(37025-55-1 free base)
      T7601L1631754-28-3
      Carbetocin acetate is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth.
      • Inquiry Price
      Size
      QTY