hearts

Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1 2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.1 It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 μM; LC50 = 865 μM).It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. In particular, it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts.

1-Heptanol (Heptan-1-ol) is a RIFM spice that is a cell membrane fluidizer and induces signaling to mast cells.1-Heptanol shows antiarrhythmic effects in atrial species of Langendorff perfused mouse hearts.1-Heptanol is a RIFM spice that is a cell membrane fluidizer and induces signaling to mast cells.1-Heptanol is a RIFM spice that is a RIFM spice and induces signaling to mast cells.

Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotective potential against myocardial is

Echinatin exerts a protective effect against ischemia reperfusion (I R)-induced myocardial injury on hearts, this effect may be attributed to the antioxidant and anti-inflammatory activities of this compound. Echinatin can inhibit DNP-ATPase activity whil

Cyclobuxine D, a steroidal alkaloid extracted from Buxus microphylla, exhibits significant bradycardia effects on rat hearts and inhibits acetylcholine and Ba++-induced longitudinal muscle contractions in isolated rabbit jejunum.

Kaempferol-7-O-β-D-glucopyranoside (Kaempferol-7-O-D-glucopyranoside), a novel supercoolant, could be used for sub-zero, non-freezing preservation of rat hearts.

Astringinin is a potent antiarrhythmic agent with cardioprotective activity in ischemic and ischemic-reperfused rat heart, the beneficial effects of astringinin in the ischemic and ischemic-reperfused hearts may be correlated with its antioxidant activity and upregulation of NO production.