hmao-a — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN2004	Obtusin		MAO , Monoamine Oxidase
	Obtusin is a natural product.		MAO , Monoamine Oxidase
T78232	hMAO-B-IN-32	Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate	MAO
	hMAO-B-IN-32 is a potent hMAO-B selective inhibitor with an IC50 of 45.52 μM.		MAO
T67879	hMAO-B-IN-5		MAO , Monoamine Oxidase
	hMAO-B-IN-5 is a potent reversible and selective human monoamine oxidase hMAO-B inhibitor (IC50:0.12μM). hMAO-B-IN-5 can cross the blood-brain barrier and can be used in the study of Parkinson's disease. It is a promisin...		MAO , Monoamine Oxidase
TN1120	Osthenol		MAO , Monoamine Oxidase
	Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promoting activity, it also has antifungal and antibacterial activ...		MAO , Monoamine Oxidase
T67764	hMAO-B-IN-4		MAO
	hMAO-B-IN-4 is a selective, reversible and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B, IC50=0.067 μM, Ki= 0.03 μM, hMAO-A, IC50= 33.82 μM).		MAO
T3596	TB5		MAO , Monoamine Oxidase
	TB5 is a potent, selective and reversible inhibitor of hMAO-B.		MAO , Monoamine Oxidase
TMS1743	Salvigenin		MAO , Autophagy , ROS Kinase
	Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.		MAO , Autophagy , ROS Kinase
TN1470	Cassiaside B2		Phosphatase , MAO , 5-HT Receptor
	Cassiaside B2 is an inhibitor of protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A).Cassiaside B2 is an agonist of the 5-HT2C receptor with anti-allergic activity.Cassiaside B2 is one of the a...		Phosphatase , MAO , 5-HT Receptor
T60891	AChE/BChE/MAO-B-IN-1		MAO , AChE
	AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1...		MAO , AChE
T0084	Moclobemide	Ro111163	MAO , Monoamine Oxidase
	Moclobemide (Ro111163) is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.		MAO , Monoamine Oxidase
T61002	hMAO-B-IN-3
	hMAO-B-IN-3 (Compound 15) is a potent hMAO-B inhibitor (IC 50 = 47.4 nM) with favourable drug-like properties and a broad safety window. Therefore, hMAO-B-IN-3 is a suitable candidate for lead optimization and multitarge...
T60658	hMAO-B/MB-COMT-IN-2
	hMAO-B/MB-COMT-IN-2 is a dual inhibitor of MAO-B/MB-COMT with IC 50s of 4.27 μΜ and 2.69 μΜ for hMAO-B and MB-COMT, respectively. hMAO-B/MB-COMT-IN-2 protects cells from oxidative damage that can be used in the neurodege...
T60489	hMAO-B/MB-COMT-IN-1
	hMAO-B/MB-COMT-IN-1 is a dual MAO-B/MB-COMT inhibitor with IC50s of 2.5 μΜ for hMAO-B and 3.84 μΜ for MB-COMT. hMAO-B/MB-COMT-IN-1 protects cells from oxidative damage that can be used in neurodegeneration disease resear...
T78690	MAO-B-IN-18		Monoamine Oxidase
	MAO-B-IN-18 is a potent, selective inhibitor of MAO B, demonstrating IC50 values of 52 nM for hMAO B and 14 μM for hMAO A. It exhibits cytoprotective effects against hydrogen peroxide-induced damage in neuroblastoma and ...		Monoamine Oxidase
T60395	Nrf2-ARE/hMAO-B/QR2 modulator 1
	Nrf2-ARE/hMAO-B/QR2 modulator 1 is a new resveratrol-based multitarget-directed ligands (MTDLs) that showed a well-balanced MTDL profile: cellular activation of the NRF2-ARE pathway (CD = 9.83 μM), selective inhibition o...
T23587	8-CSC	8 CSC,CSC
	8-CSC is a dual agent endowed with good hMAO-B inhibitory activity (Ki: 235 nM in baboon liver mitochondria) and A2A affinity (Ki: 36 nM in rat brain striatal membranes receptor).
T40628	Chrysophanol-1-O-β-gentiobioside
	Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside obtained from the seeds of Cassia obtusifolia, exhibits targeted inhibition of hMAO-A isozyme activity with an IC50 value of 96.15 μM.
T81866	MAO-B-IN-27		Monoamine Oxidase
	MAO-B-IN-27 (Compound 12c), a monoamine oxidase B (MAO-B) inhibitor, exhibits a potent and selective inhibitory effect on hMAO-B, with an IC50 value of 8.9 nM, and is utilized in Parkinson's disease (PD) research [1].		Monoamine Oxidase
T36950	Rubrofusarin triglucoside
	Rubrofusarin triglucoside, a glycoside isolated from Cassia obtusifolia Linn seeds, demonstrates inhibitory activity against human monoamine oxidase A (hMAO-A), exhibiting an IC50 value of 85.5 μM[1].
T61603	H3R antagonist 2
	H3R antagonist 2 (Compound 23) is a multitarget histamine H3 receptor antagonist. It exhibits inhibitory effects on acetylcholinesterase, butyrylcholinesterase, and human monoamine oxidase B (hMAO B) with IC50 values of ...