glycine

glycine (2-Aminoacetic acid) is a non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

Z-Glycine (Carbobenzoxyglycine) is a drug-lipid conjugates designed to promote brain penetration based on its lipophilicity and resemblance to lipids in biological membranes[1].

N-Oleoyl Glycine, a Lipoamino Acid, Stimulates Adipogenesis Associated With Activation of CB1 Receptor and Akt Signaling Pathway in 3T3-L1 Adipocyte

(RS)-(Tetrazol-5-yl)glycine is a potent and selective N-methyl-D-aspartate (NMDA) receptor agonist that can induce seizure models and Fos expression in mice. Its EC50 values for GluN1/GluN2D and GluN1/GluN2A are 99 nM and 1.7 μM, respectively.

2,3-Indolobetulinic glycine amide is a pentacyclic triterpene and derivative of betulinic acid .1It has been used in the synthesis of betulinic acid derivatives with anticancer activity. 1.Kumar, V., Rani, N., Aggarwal, P., et al.Synthesis and cytotoxic activity of heterocyclic ring-substituted betulinic acid derivativesBioorg. Med. Chem. Lett.18(18)5058-5062(2008)

The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Docosahexaenoic acid (DHA), a C22:6 PUFA, is the most abundant ω-3 fatty acid in neural tissues, especially in the retina and brain. It can be synthesized from other dietary ω-3 PUFAs or taken as a nutritional supplement. Docosahexaenoyl glycine consists of DHA with glycine attached at its carboxy terminus.

Betulinic glycine amide, a pentacyclic triterpenoid derivative of betulinic acid, serves as a precursor for synthesizing derivatives with anticancer and antiviral activity.

N-(Phenylacetyl-D5)Glycine (Standard) is a reference standard of N-(Phenylacetyl-D5)Glycine intended for quantitative analysis, quality control, and related biochemical research applications. N-(Phenylacetyl-d5)glycine is the deuterated form of Phenylacetylglycine. It is a metabolite produced by gut microbiota and functions as an activator of β2AR. Additionally, Phenylacetylglycine provides protective benefits against cardiac damage caused by ischemia/reperfusion.

Glycine-CoA (Glycine-coenzyme A) is a derivative of coenzyme A.

Gamma-glutamyl[S-(2-iodobenzyl)cysteinyl]glycine-CoA (Gamma-glutamyl[S-(2-iodobenzyl)cysteinyl]glycine-coenzyme A) is a derivative of coenzyme A.

N-[Amino(Imino)methyl]glycine-CoA (N-[Amino(Imino)nethyl]glycine-coenzyme A) is a derivative of coenzyme A.

Glycylglycine (Diglycine) is a dipeptide used in biochemical research. It is the simplest of all dipeptides and is used as a starting template for preparation of more complex peptides. Glycine is involved in the body's production of DNA, phospholipids, and collagen, and in the release of energy.

DL-Propargylglycine HCl (DL-Propargyl Glycine HCl) is a potent irreversible inhibitor of cystathionine γ-cleaving enzyme and can be used in the study of heart failure.

N-Arachidonylglycine (NA-Gly) is a heat-dependent circulating metabolite with anti-inflammatory, anticancer, antidiabetic and antioxidant activities.

Glycine (Standard) is a reference standard for research and analysis in studies involving glycine. Glycine is an inhibitory neurotransmitter in the central nervous system and a co-agonist of glutamate, enhancing NMDA receptor excitability. It is found in gelatin and silk fibroin and is used as a nutrient in medical treatments.

N-Palmitoyl Glycine is an endogenous lipid that modulates calcium influx and nitric oxide (NO) production in sensory neurons. It is associated with an increased risk of Brugada syndrome (BrS), interacts with BrS-related proteins, and shows moderate binding affinity to molecules including DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA.

Hexanoyl Glycine is an acylated amino acid and endogenous metabolite serving as a urinary biomarker, exhibiting inhibitory activity against tyrosinase and urease.

N-(3-Phenylpropionyl)glycine (Phenylpropionylglycine) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. Acyl glycines are produced through the action of glycine N-acyltransferase which is an enzyme that catalyzes the chemical reaction:acyl-CoA + glycine < - > CoA + N-acylglycineThe detection of phenylpropionylglycine in urine after an oral load of phenylpropionic acid can be used to diagnose deficiency of medium-chain acyl-CoA dehydrogenase, a frequent and treatable metabolic defect.

Linoleoyl glycine, a modified polyunsaturated fatty acid, is an endogenous homologue of linoleoyl glycine. Linoleoyl glycine activates human KCNQ1/KCNE1 (hKCNQ1/hKCNE1) channels expressed in xenopus oocytes from mammalian skin, spinal cord and brain, and has shown analgesic activity in animal studies.

Glycine-1-13C (Standard) is a reference standard of Glycine-1-13C intended for quantitative analysis, quality control, and related biochemical research applications. Glycine-1-13C is 13C-labeled glycine. Glycine functions as an inhibitory neurotransmitter in the central nervous system and acts as a co-agonist with glutamate, enhancing the excitatory potential of glutamatergic NMDA (N-methyl-D-aspartic acid) receptors.

Glycine-2-13C,15N (Standard) is a reference standard of Glycine-2-13C,15N intended for quantitative analysis, quality control, and related biochemical research applications. Glycine-2-13C,15N is a form of glycine labeled with 13C and 15N isotopes. Glycine acts as an inhibitory neurotransmitter in the central nervous system and serves as a co-agonist with glutamate, possessing the potential to enhance the excitatory function of glutamatergic NMDA (N-methyl-D-aspartic acid) receptors.

Glycine-13C2,15N (Standard) is a reference standard of Glycine-13C2,15N intended for quantitative analysis, quality control, and related biochemical research applications. Glycine-13C2,15N is a form of Glycine labeled with both 13C and 15N isotopes. Glycine acts as an inhibitory neurotransmitter in the central nervous system and serves as a co-agonist to glutamate, with the potential to enhance the excitation of glutamatergic NMDA (N-methyl-D-aspartic acid) receptors.

Glycine-D2 (Standard) is a reference standard of Glycine-D2 intended for quantitative analysis, quality control, and related biochemical research applications. Glycine-d2 is a deuterated compound of Glycine. Glycine has a CAS number of 56-40-6. Glycine is a non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

Glycine-D3 (Standard) is a reference standard of Glycine-D3 intended for quantitative analysis, quality control, and related biochemical research applications. Glycine-d3 is the deuterated form of Glycine. Glycine functions as an inhibitory neurotransmitter in the central nervous system and acts as a co-agonist for glutamate, enhancing the excitatory potential of glutamatergic NMDA (N-methyl-D-aspartic acid) receptors.