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Results for "

falciparum

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    269
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    1
    TargetMol | Peptide_Products
  • Natural Products
    75
    TargetMol | Natural_Products
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    9
    TargetMol | Recombinant_Protein
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    2
    TargetMol | Isotope_Products
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    TargetMol | Antibody_Products
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    2
    TargetMol | Inhibitors_Agonists
Nanaomycin A
T1626952934-83-5
Nanaomycin A, a quinone antibiotics, reactivates silenced tumor suppressor genes in human cancer cells. Nanaomycin A is a selective inhibitor of DNMT3B (IC50 = 500 nM).
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Cycloheximide
Naramycin A, CHX, Actidione
T122566-81-9
Cycloheximide (Naramycin A) is a natural product that reversibly inhibits translation elongation, is an antimitotic compound, and is an inhibitor of DNA and protein synthesis.
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TargetMol | Inhibitor Hot
Artelinic acid
T10378120020-26-0In house
Artelinic acid is a water-soluble artemisinin analog with antimalarial activity and is used for the treatment of multi-drug resistant strains of Plasmodium falciparum.
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6-8 weeks
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CWHM-1552
T109032368253-58-9In house
CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.
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8-10 weeks
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TargetMol | Inhibitor Sale
DHODH-IN-4
T110271148125-93-2In house
DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor. The IC50 values of PfDHODH and HsDHODH are 4 μM and 0.18 μM, respectively. DHODH-IN-4 has antimalarial activity.
  • Inquiry Price
6-8 weeks
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DHODH-IN-8
T110301148126-03-7In house
DHODH-IN-8 has antimalarial activity. DHODH-IN-8 is an inhibitor of human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) with IC50 of 0.13 μM and 47.4 μM, and Kis of 0.016 μM and 5.6 μM, respectively.
  • Inquiry Price
6-8 weeks
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Didesethyl chloroquine
Bisdesethylchloroquine
T110394298-14-0In house
Didesethyl chloroquine (Bisdesethylchloroquine) is an effective myocardial inhibitor. Didesethyl chloroquine (Bisdesethylchloroquine) is the main metabolite of the antimalarial drug chloroquine.
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6-8weeks
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TargetMol | Inhibitor Sale
Dehydroemetine
T150954914-30-1In house
Dehydroemetine is an effective antigenic insecticide, which is a synthetic analogue of Emetine dihydrochloride. It can be used to prevent and treat amoeba infections and diseases. It has the effect of treating leishmania infection with skin damage and resistance to metronidazole amoebiosis.
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8-10weeks
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Lasalocid A ammonium
Lasalocid A ammonium(25999-31-9 Free base)
T15717L33855-11-7In house
Lasalocid A ammonium is an amine-selective ion carrier and feed additive with antimicrobial activity and antibiotic, growth-promoting properties, inhibits the protozoa of falciparum malaria, and can be used in the study of microbial infections.
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Cipargamin
NITD609, KAE609
T163261193314-23-6In house
Cipargamin (NITD609) is an effective antimalarial compound. It has an IC50 of appr 1 nM against P. falciparum.
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WR99210 hydrochloride(47326-86-3 free base)
WR99210 hydrochloride(47326-86-3 free base), 6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine
T17257L30711-93-4In house
WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.
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Rufigallol
AI3 00865, AI3-00865, AI300865
T2616882-12-2In house
Rufigallol (AI3-00865) is an electron-deficient disk-shaped molecule with six hydroxyl groups and is a good unit for inducing the formation of DLC from non-planar AIE molecules, an anthraquinone derivative.Rufigallol induces the acquisition of DLC properties, while the introduction of TPE groups gives the molecular structure good fluorescence in the aggregated state.The remarkable synergistic in vitro antimalarial effect, in vivo with vitamin C and ketones was synergistic and showed antimalarial activity.
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6-8weeks
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TargetMol | Inhibitor Sale
DSM421
DSM 421, DSM-421
T272142011769-21-2In house
DSM421 (DSM-421) is a dihydrodehydrogenase inhibitor (DHODH) that is in preclinical development as a potential treatment option for malaria and has shown activity against field isolates of both P. falciparum and P. vivax.
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6-8 weeks
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Pyronaridine
T549374847-35-1In house
Pyronaridine is an orally active, mannitol-containing anti-malarial compound that acts by interfering with the replication of the malaria parasite (Plasmodium) within red blood cells. Pyronaridine is often used in combination with other drugs to treat malaria and has infective activity against P. falciparum and Echinococcus granulosus.
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TargetMol | Inhibitor Sale
ZY-19489
T676941821293-40-6In house
ZY-19489 is an antimalarial compound that is a potential single-dose cure for Plasmodium falciparum and Plasmodium vivax malaria. It has received orphan drug designation from the FDA.
  • Inquiry Price
8-10weeks
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TargetMol | Inhibitor Sale
MMV688533
T676952260904-47-8In house
MMV688533 has antimalarial activity.
  • Inquiry Price
8-10weeks
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UCB7362 hydrochloride
UCB7362 hydrochloride(2610631-17-7 Free base), UCB7362 HCl
T69567L2610631-18-8In house
UCB7362 hydrochloride (UCB7362 HCl) is an orally active plasmepsin X (PMX) inhibitor (IC50: 7 nM) with antimalarial activity that inhibits parasite growth.
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Antimalarial agent 30
T795351597425-64-3In house
Antimalarial agent 30 has anti-Plasmodium berghei liver stage parasite activity and antimalarial activity for the study of malarial infections.
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6-8weeks
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(-)-Anonaine
TN13931862-41-5In house
(-)-Anonaine can be extracted from several species of Magnoliaceae and Annelidae and has antimalarial, antibacterial, antifungal, antioxidant, anticancer, antidepressant and vasodilatory activities. (-)-Anonaine induces apoptosis in human cervical cancer (HeLa) cells, induces DNA damage and inhibits the growth and migration of human lung cancer h1299 cells through Bax and caspase-dependent pathways.
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8-10 weeks
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Azlocillin sodium salt
Sodium azlocillin, Azlocillin sodium
T004937091-65-9
Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics
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Mefloquine hydrochloride
Mefloquin hydrochloride, Mefloquine HCl
T086051773-92-3
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
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Hexyl gallate
Gallic acid hexyl ester, Hexyl 3,4,5-trihydroxybenzoate
T115581087-26-9
Hexyl gallate (Gallic acid hexyl ester), an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM).
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Atovaquone
Atavaquone
T149195233-18-4
Atovaquone (Atavaquone) is a hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.
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Ascaridole
NSC-406266, NSC406266, NSC 406266
T25114512-85-6
Ascaridole (NSC-406266) acts as an anthelmintic compound that repels parasitic helminths (worms) in humans and plants and has weak antimalarial activity.
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