dye reagent

AkaLumine hydrochloride is a luciferin analog, a luciferase substrate (Km=2.06 μM), emitting near-infrared light (λmax=677 nm) with high tissue penetration, used for deep tissue bioimaging research.

Hoechst 33342 (bisBenzimide H 33342) is a lipophilic fluorescent dye belonging to the bisbenzimidazole class and a cell-permeable fluorescent DNA dye. Hoechst 33342 can penetrate the membranes of living cells to achieve non-invasive staining of live cell nuclei, exhibiting excellent fluorescence properties and extremely low cytotoxicity.

MitoSOX Red is a fluorescent dye serving as a mitochondria-targeted fluorescent probe for superoxide, with cell membrane permeability and specificity. Upon oxidation, MitoSOX Red subsequently binds to nucleic acids within mitochondria/nuclei, producing intense red fluorescence, and is employed for detecting mitochondrial superoxide in live cells.

Ponceau 4R (Acid Red 18) is a synthetic strawberry red azo dye that is a food colorant dye used in a variety of food products. It is stable to light, heat and acid, but fades in the presence of ascorbic acid. It is usually synthesized from aromatic hydrocarbons.

IR-820 (New Indocyanine Green) is a near-infrared dye with improved stability, good color rendering, and excellent fluorescence penetration. It serves as an infrared blood pool contrast agent for detecting and quantifying diseased tissue in live animals, with maximal excitation (Ex) and emission (Em) of 710 and 820 nm, respectively.

2-(4-Hydroxyphenylazo)benzoicacid is a spectrophotometric probe that shows changes in absorption spectra upon binding to proteins and binds to bovine serum proteins.

HOE-S 785026 trihydrochloride is a live cell labeling dye that binds to nucleic acids by targeting the minor groove in DNA double strands, with a preference for A/T-rich regions (fluorescence is significantly enhanced by A/T-rich double-stranded DNA). It crosses cell membranes and binds to living or immobilized cells, with its fluorescence intensity increasing as the solution pH rises.

Bromobimane (Monobromobimane) is a non-fluorescent substance, but reacts with thiols to produce a fluorescent product.Bromobimane is used as a probe, often in clinical medicine, to test for sulfide levels in blood.

Py-BODIPY-NHS ester is a small molecular dye with strong UV absorption that can be used to label living cells and immobilise cells.

Fluorescein Biotin is a biotin-substituting fluorescent dye that detects and quantifies biotin binding sites by fluorescence or absorbance.Fluorescein Biotin undergoes fluorescence quenching when bound to avidin or streptavidin.

Monochlorobimane (mBBr) is a fluorescent dye with a λex value of 380 nm and a λem value of 470 nm.Monochlorobimane can be used to measure glutathione (GSH) in cells.

4',5'-Dibromofluorescein (Eosinic acid) is a fluorescent dye utilized as a ligand in protein characterization through spectroscopic analysis.

FlAsH-EDT2 is a membrane-permeable fluorescent reagent that can label proteins. FlAsH-EDT2 can bind to CCXXCC motifs and nonspecific endogenous cysteine-rich proteins. FlAsH-EDT2 can only be used to label recombinant proteins that are expressed at very high levels.

Quinacrine mustard hydrochloride is a fluorescent dye and polycyclic aromatic agent that acts as a mutagen to induce mutants in bacteria.Quinacrine mustard hydrochloride selectively binds to adenine-thymine (AT) base pairs, but not to guanine-cytosine (GC). Quinacrine mustard (hydrochloride) selectively binds to adenine-thymine (AT) base pairs rather than to guanine-cytosine (GC) base pairs, inducing cell cycle arrest at G2/M. Quinacrine mustard (hydrochloride) has been used to label chromosomes for karyotyping by autoradiography.

Ferrozine monosodium salt is a dye that reacts with divalent iron to form a stable magenta complex that can be used for the spectrophotometric determination of iron.

MHI-148 is a tumor-targeting near-infrared heptamethylenecarbocyanine dye for the detection, diagnosis, and study of cancer.MHI-148 is taken up and accumulates in the lysosomes and mitochondria of tumor cells but is not taken up in the lysosomes and mitochondria of normal cells.MHI-148 is a tumor-targeting near-infrared heptamethylenecarbocyanine dye for the detection and diagnosis of cancer.

Xylenolblue (p-Xylenol Blue) is an acid-base indicator used as an intermediate in chemical synthesis.

Nuclear Fast Red is an anthraquinone dye that serves as a red nuclear counterstain when aluminum ions are present in excess, thereby aiding in histological visualization of nuclear components. Nuclear Fast Red additionally functions as a histochemical and colorimetric reagent for calcium detection,Nuclear Fast Red further acts as a highly sensitive “off/on” fluorescent probe for the detection of guanine, making it a multifunctional research reagent.

Hydroxystilbamidine bis(methanesulfonate) is a fluorescent cationic dye that binds strongly to DNA and RNA, and is widely used as a retrograde neuronal tracer, while also acting as a potent inhibitor of cellular ribonucleases, making it a versatile research reagent for neuroanatomical tracing, nucleic acid labeling, and studies of RNA stability and degradation.

Sulforhodamine-PEG4-DBCO is a PEG derivative comprising a DBCO group and a rhodamine dye. DBCO enables copper-free click chemistry, reacting with azide-containing compounds or biomolecules to form stable triazole linkages. This reagent is an ideal alternative for applications intolerant to copper, suitable for labeling cells, tissues, biomarkers, or nanoparticles.

Chitosan-PEG-Cy3 is a fluorescent labeling reagent that combines the Cy3 fluorescent dye with Chitosan and polyethylene glycol (PEG). Cy3 fluorophores are frequently utilized in applications like immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Chitosan exhibits antimicrobial activity against various bacteria and fungi.

RGD-PEG-Cy3 is a fluorescent labeling reagent that combines the Cy3 fluorescent dye, peptide (RGD), and polyethylene glycol (PEG). The Cy3 fluorophore is commonly employed in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry, with a peak emission wavelength of approximately 562-570 nm. RGD is a peptide sequence (CRGDKGPDCiRGD) that targets tumor tissues specifically by binding to αvβ3 and αvβ5 integrin receptors, which are involved in tumor neovascularization.