dopamine

Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter that mainly acts on dopamine receptors (D1-5 receptors) (EC50=2.7 nM). Dopamine hydrochloride induces VEGFR2 endocytosis through D2 dopamine receptor and has pro-angiogenic activity.

Octodrine (2-Amino-6-methylheptane) is primarily used as a pharmaceutical intermediate for Octamylamine; it also functions as a local anesthetic and vasoconstrictor.

Citicoline (CDP-Choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.

Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) is a biogenic monoamine structurally associated with noradrenaline. It can serve as a neurohormone, a neurotransmitter, and a neuromodulator in invertebrates.

Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.

Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.

L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively).

Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.

D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes, and attenuate the viability reduction and LDH release of the prim

Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of human breast cancer cells by MMP-9 i

Hirsuteine is a natural product. It non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes.

2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway.

Syrosingopine is a dual inhibitor of MCT1 and MCT4, 60 times more potent against MCT4, preventing lactate and H+ efflux. Syrosingopine is an orally available antihypertensive drug with potential for cancer research in combination with metformin.

Nuciferine ((-)-Nuciferine) is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera. It has a profile of action associated with dopamine receptor blockade.

Dopamine 3-O-sulfate, primarily found in plasma, serves as a biomarker for identifying aromatic amino acid decarboxylase (AADC) deficiency [1].

Dopamine hydrochloride (Standard) is the standard substance of Dopamine hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter that mainly acts on dopamine receptors (D1-5 receptors) (EC50=2.7 nM). Dopamine hydrochloride induces VEGFR2 endocytosis through D2 dopamine receptor and has pro-angiogenic activity.

5-S-Cysteinyldopamine is a thioether metabolite of dopamine that can induce neurological damage by causing extensive oxidative stress and protein aggregation. This is characterized by protein carbonylation, glutathione depletion, and increased expression of α-synuclein (α-Syn) and ERp57 proteins. It is applicable in research on neurodegenerative diseases such as Parkinson's disease.

5-Hydroxydopamine hydrochloride is a naturally occurring amine in human urine with an IC50 value of 22 µM for the Luxaphone receptor.5-Hydroxydopamine has potential antimicrobial and anticancer activities.5-Hydroxydopamine hydrochloride is a natural amine in human urine with an IC50 value of 22 µM for the Luxaphone receptor.

N-acetyldopamine (NADA) is a catecholamine used by insects as a precursor for sclerotization, a process that strengthens their cuticle.

N-Acetyldopamine dimer-3 (Compound 11), a naturally occurring chemical, is present in the species Aspongopus chinensis [1].

N-Acetyldopamine dimer-1, a 2-(3',4'-dihydroxyphenyl)-1,4-benzodioxane derivative, is optically active and can be isolated from the crude agent Zentai, the cast-off shell of the cicada of Cryptotympana sp. (Cicadidae) [1].

N-Acetyldopamine dimers B is a dimer form of N-Acetyldopamine [1] [2].

N-Acetyldopamine dimers A (Compound (+)-2) can be isolated from the cast-off shell of the cicada Cryptotympana sp. and increase collagen and α-SMA expression [1].

L-DOPA (Levodopa) is an orally active metabolic precursor of the neurotransmitter dopamine. It can cross the blood-brain barrier and be converted into dopamine in the brain. L-DOPA exhibits anti-hyperalgesic effects and holds potential in Parkinson’s disease research, and it can also be used to induce Parkinson’s disease models.