chemical

Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.

Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.

Carbetamide (Caswell No. 159B) is a herbicide with a good reproduction of mobility in the soil.

Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.

Azothoate is an insecticide agent.

Iodofenphos is an obsolete insecticide.

CCCI-01(Centrosome Clustering Chemical Inhibitor-01) is a centrosome cluster inhibitor. CCCI-01 has anticancer activity, induces apoptosis, and can be used in the study of non-cross-resistant anticancer compounds that block centrosome clustering.

Tralomethrin is used as a pyrethroid insecticide. It modifies the gating kinetics of the sodium channels in neurons, increases the length of time the channel remains open after a stimulus, thereby depolarizing the neuron for a longer period of time. This leads to uncontrolled spasms, paralysis, and eventual death.

BRD-K25923209 is a novel inhibitor of BAF transcriptional repression.

Chemical phosphorylation amidite is a potent chemoselective reagent characterized by its azide groups. Chemoselectivity denotes a powerful chemical reaction that showcases excellent biocompatibility, rapidity, and high specificity within biological environments.

HEPES is a zwitterionic sulfonic acid buffering agent, commonly used to uphold a neutral pH of basal medium within cell cultures.HEPES is a potent inducer of lysosome biogenesis.

Bentazone is a selective post-emergence herbicide that interferes with photosynthesis, used to suppress broadleaf weeds and sedges.

Uridine,2',3'-o-(1-methylethylidene)-,4-oxidechemicalbook,5'-(2-methylpropanoate) is a pharmaceutical intermediate used in the synthesis of various active compounds.

Itaconic acid is a precursor for the synthesis of polymers, chemicals, and fuels, and has anti-inflammatory activity.Itaconic acid can be synthesized by fungi. It is also a macrophage-specific metabolite. It mediates crosstalk between macrophage metabolism and peritoneal tumors.

It is an isomer of cresotinic acid (2-hydroxy-3-methylbenzoic acid) and oxymethylbenzoic acid (2-methoxybenzoic acid). Derivatives of mandelic acid are formed as a result of metabolism of adrenaline and noradrenaline by monoamine oxidase and catechol-o-methyl transferase. It is also present in certain skin care products, is an intermediate molecule in the production of other biochemicals, may be used as an analytical reagent and is a precursor in the manufacture of dyes. Mandelic acid (acidomandelico) is found to be associated with phenylketonuria, which is an inborn error of metabolism.

Sabinene is a natural product that has antifungal and anti-inflammatory properties

CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).

DHX9-IN-18 is an inhibitor of RNA helicase DHX9 with an EC50 of 16.4 μM and a biochemical infection point of 0.32 μM. This compound can be used as a research tool in cancer-related research fields.

Ketorolac (RS37619) hemicalcium is a nonselective COX inhibitor with IC50 values of 20 nM for COX-1 and 120 nM for COX-2. This non-steroidal anti-inflammatory drug (NSAID) is used as a 0.5% ophthalmic solution for researching allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Additionally, it is a DDX3 inhibitor applicable in cancer research [1] [4].

Cationic Bovine Serum Albumin is a protein composed of 583 amino acids and contains three homologous all-α domains. When used in combination with Tanshinone IIA , it exhibits significant neuroprotective effects in ischemic stroke. It is also commonly used to induce membranous nephropathy (MN) models.

ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays.

Valspodar (PSC 833), a specific P-glycoprotein inhibitor and MDR regulator, is commonly used as a chemical sensitizer in the study of advanced epithelial ovarian cancer.

Anticonvulsant agent 1 is a chemical compound with potent anticonvulsant properties.

BAY-678 is a human neutrophil elastase (HNE; IC50: 20 nM) inhibitor with oral bioactivity, potency and selectivity.BAY-678 is a chemical probe recommended by the Structural Genomics Consortium (SGC).