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Search Result

Search Results for " channel "

Targets

Chloride channel Calcium Channel Sodium Channel Potassium Channel Piezo Channel TRP/TRPV Channel HCN Channel Calcium Channel CDK

1138

Compounds

134

Natural Products

105

Recombinant Proteins

6

Libraries

Cat No. Product Name Synonyms Targets
T10659 Ca2+ channel agonist 1 Calcium Channel , CDK
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction.
T77710 Calcium Channel antagonist 2 WAY-327363 Calcium Channel
Calcium Channel antagonist 2 is a calcium channel antagonist (IC50=5-20 μM) that can be used to study diseases due to Ca2+ channels like pain and diabetes.
T10101 Calcium channel-modulator-1 Others , Calcium Channel
Calcium channel-modulator-1 is a calcium channel-modulator (IC50:0.8 μM) with specialisation to block aortic constriction.
T10674 Potassium Channel Activator 1 ZINC34634569 Potassium Channel
Potassium Channel Activator 1 can be used in studies about the treatment of disorders or conditions wherein the dopaminergic system is disrupted such as mood disorders ADHD, schizophrenia, and other psychotic states.
T77711 Calcium Channel antagonist 4 Calcium Channel
Calcium Channel antagonist 4 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).
T77712 Calcium Channel antagonist 3 Calcium Channel
Calcium Channel antagonist 3 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).
T72170 NaV1.2/1.6 channel blocker-1 Sodium Channel
NaV1.2/1.6 channel blocker-1 is a potent NaV1.2/1.6 channel blocker with inhibitory effects on rNaV1.6 and hNaV1.2.NaV1.2 channel blocker-1 can be used in the study of generalised epilepsy and movement disorders.
T11927 M2 ion channel blocker Others
M2 ion channel blocker ,Antiviral agent, is capable of inhibiting and blocking the activity of M2 ion channel.
T12951 Sodium Channel inhibitor 2 Sodium Channel
Sodium Channel inhibitor 2 is a blocker of sodium channel.
T12948 Sodium Channel inhibitor 1 Others
Sodium Channel inhibitor1 is a novel and selective voltage-gated sodium channel for pain treatment. (IC50 Value of 0.16 uM and 0.41 uM for Na v1.7, V hold-90mV and Na v1.7, V hold-90mV)
T12153 N-type calcium channel blocker-1 Calcium Channel
N-type calcium channel blocker-1 is an orally active analgesic agent,shows high affinity to functionally block N-type calcium channels.
TP1491 Kv3, Channel Containing Protein 567-585
Kv3 channel protein is expressed by parvalbumin (PV)-containing pallidal neurons.Kv3, Channel Containing Protein (567-585) corresponds to amino acids 567 to 585 fragment of the Kv3.1b channel containing protein.
T81134 Sodium Channel inhibitor 4 Sodium Channel
Sodium Channel Inhibitor 4 is a compound that functions as a sodium channel inhibitor [1].
T60985 KCa2 channel modulator 1
KCa2 channel modulator 1 (compound 2o) is an effective subtype-selective K/Ca2 channel positive modulator that potentiates rat K Ca 2.2 channel subtype with an EC 50 value of 0.99 μM and human K Ca 2.3 channels subtype w...
T61605 SK3 Channel-IN-1
SK3 Channel-IN-1 (compound 7a) is a powerful and selective modulator of the SK3 channel. It demonstrates significant efficacy in inhibiting breast cancer MDA-MB-435 cell migration while maintaining low cytotoxicity in ot...
T72194 KCa1.1 channel activator-1
KCa1.1 Channel Activator-1, a hybrid derivative of Quercetin, selectively stimulates the vascular KCa1.1 channels while also blocking CaV1.2 channels. Additionally, it demonstrates weak myorelaxant activity.
T72195 KCa1.1 channel activator-2
KCa1.1 channel activator-2, a hybrid derivative of Quercetin, selectively stimulates the vascular KCa1.1 channels. This compound demonstrates significant myorelaxant activity.
T60986 KCa2 channel modulator 2
KCa2 channel modulator 2 (compound 2q) is an effective subtype-selective K/Ca 2 channel positive modulator which shows similar potency on the human K Ca 2.3 channel and rat K Ca 2.2a subtypes, with EC50 values of 0.60 μM...
T79280 Nav1.3 channel inhibitor 1 Sodium Channel
Nav1.3 Channel Inhibitor 1 (Compound 15b) is a state-dependent inhibitor of the voltage-gated sodium channel Na v 1.3, with an IC50 value of 20 nM. It has the ability to cross the blood-brain barrier, making it applicabl...
T64203 T-Type calcium channel inhibitor 2
T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, acting on Cav3.1 (α1G) (IC50: 31.0 μM), Cav3.2 (α1H) (IC50: 83.1 μM), Cav3.3 (α1I) (α1H) ( T-Type calcium channel inhi...
T15385 Glibornuride Potassium Channel
Glibornuride is an ATP-sensitive K+ channels (KATP channel) blocker ( pKi: 5.75). It is an antidiabetic agent.
T10979 DCPIB Potassium Channel , Chloride channel
DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM, demonstrating at least 100-fold higher affinity over TREK1...
T4294 NS 11021 NS11021 Potassium Channel
NS 11021 (NS11021) , a novel opener of large-conductance Ca(2+)-activated K(+) channels
T20968 CyPPA Potassium Channel , Dopamine Receptor
CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolarization.
T10977 DCEBIO Potassium Channel
DCEBIO stimulates the secretion of Cl- through the activation of the hIK1 K + channel and the activation of the apical Cl- conductance. DCEBIO is a derivative of 1-EBIO and a very strong activator of Cl- secretion by T84...
T27624 Iptakalim Hydrochloride Potassium Channel , AChR
Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine receptor (nAChR) antagonist. Iptakalim is also a K(ir) 6.1/SUR2...
T0030 Bupivacaine hydrochloride Vivacaine,Bupivacaine HCl Sodium Channel
Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the vol...
T80530 Spinoxin SPX,α-KTx6.13,Potassium channel toxin alpha-KTx 6.13 Potassium Channel
Spinoxin, a 34-residue peptide neurotoxin extracted from the venom of Heterometrus spinifer, is characterized by four disulfide bridges. It acts as a potent inhibitor of the Kv1.3 potassium channel with an IC 50 value of...
T7638 NPPB Chloride channel
NPPB is a chloride channel blocker with IC50 of 80 nM .
T2519 Lercanidipine Masnidipine Calcium Channel
Lercanidipine (Masnidipine) is a calcium channel blocker of the dihydropyridine class.
T13320L VU591 Potassium Channel
1222810-74-3
T15192 Eact Chloride channel
Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity.
T8960 MONNA Chloride channel
MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions.
T3102 NS-1619 Apoptosis , Potassium Channel
NS1619 have cardio-protective effects after ischemia-reperfusion injury.
T1752 NS6180 Potassium Channel
NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.
T12421 PF-04885614 Sodium Channel
PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.
T5850 Benzamil Benzamil (hydrochloride) Na+/Ca2+ Exchanger , Sodium Channel
Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane vesicles.
T0916 Butamben Butyl 4-aminobenzoate Potassium Channel , Calcium Channel , Sodium Channel
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
T0386L Ropivacaine LEA-103 HCl Potassium Channel , Sodium Channel
Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.
T13164 Tipepidine hydrochloride Potassium Channel , Dopamine Receptor
Tipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effect.
T40042 Evifacotrep TRP/TRPV Channel
Evifacotrep is a short transient receptor potential channel 5 ( TRPC5 ) antagonist (WO2020061162, compound 100). Evifacotrep can be used for the research of neurological diseases.
T8581 Flecainide hydrochloride Others
Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.
T2604 1-EBIO Calcium Channel
1-EBIO (1-EBIO) is a calium channel agonist.
T0858 Flufenamic acid Arlef,Nichisedan,Achless Potassium Channel , Calcium Channel , Chloride channel , COX , AMPK , Parasite
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically.
T0386 Ropivacaine hydrochloride Ropivacaine monohydrochloride Potassium Channel , Sodium Channel
Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity.
T1765 Erastin Ferroptosis , VDAC
Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner. Erastin has anti-tumor activity and acts selectively on tumor cells with RAS-carcinogenic mutations. The product...
T9714 Atpenin A5 Potassium Channel
Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1].
T14982 Clofilium tosylate Potassium Channel
Clofilium tosylate is a potassium channel blocker. It induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3.
T8674 SR33805 Calcium Channel
SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)
T19723 AMTB hydrochloride AMTB TRP/TRPV Channel
AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive refl...

Compounds

Ca2+ channel agonist 1
T10659
Synonym:
Target: Calcium Channel, CDK
Calcium Channel antagonist 2
T77710
Synonym: WAY-327363
Target: Calcium Channel
Calcium channel-modulator-1
T10101
Synonym:
Target: Others, Calcium Channel
Potassium Channel Activator 1
T10674
Synonym: ZINC34634569
Target: Potassium Channel
Calcium Channel antagonist 4
T77711
Synonym:
Target: Calcium Channel
Calcium Channel antagonist 3
T77712
Synonym:
Target: Calcium Channel
NaV1.2/1.6 channel blocker-1
T72170
Synonym:
Target: Sodium Channel
M2 ion channel blocker
T11927
Synonym:
Target: Others
Sodium Channel inhibitor 2
T12951
Synonym:
Target: Sodium Channel
Sodium Channel inhibitor 1
T12948
Synonym:
Target: Others
N-type calcium channel blocker-1
T12153
Synonym:
Target: Calcium Channel
Kv3, Channel Containing Protein 567-585
TP1491
Synonym:
Target:
Sodium Channel inhibitor 4
T81134
Synonym:
Target: Sodium Channel
KCa2 channel modulator 1
T60985
Synonym:
Target:
SK3 Channel-IN-1
T61605
Synonym:
Target:
KCa1.1 channel activator-1
T72194
Synonym:
Target:
KCa1.1 channel activator-2
T72195
Synonym:
Target:
KCa2 channel modulator 2
T60986
Synonym:
Target:
Nav1.3 channel inhibitor 1
T79280
Synonym:
Target: Sodium Channel
T-Type calcium channel inhibitor 2
T64203
Synonym:
Target:
Glibornuride
T15385
Synonym:
Target: Potassium Channel
DCPIB
T10979
Synonym:
Target: Potassium Channel, Chloride channel
NS 11021
T4294
Synonym: NS11021
Target: Potassium Channel
CyPPA
T20968
Synonym:
Target: Potassium Channel, Dopamine Receptor
DCEBIO
T10977
Synonym:
Target: Potassium Channel
Iptakalim Hydrochloride
T27624
Synonym:
Target: Potassium Channel, AChR
Bupivacaine hydrochloride
T0030
Synonym: Vivacaine,Bupivacaine HCl
Target: Sodium Channel
Spinoxin
T80530
Synonym: SPX,α-KTx6.13,Potassium channel toxin alpha-KTx 6.13
Target: Potassium Channel
NPPB
T7638
Synonym:
Target: Chloride channel
Lercanidipine
T2519
Synonym: Masnidipine
Target: Calcium Channel
VU591
T13320L
Synonym:
Target: Potassium Channel
Eact
T15192
Synonym:
Target: Chloride channel
MONNA
T8960
Synonym:
Target: Chloride channel
NS-1619
T3102
Synonym:
Target: Apoptosis, Potassium Channel
NS6180
T1752
Synonym:
Target: Potassium Channel
PF-04885614
T12421
Synonym:
Target: Sodium Channel
Benzamil
T5850
Synonym: Benzamil (hydrochloride)
Target: Na+/Ca2+ Exchanger, Sodium Channel
Butamben
T0916
Synonym: Butyl 4-aminobenzoate
Target: Potassium Channel, Calcium Channel, Sodium Channel
Ropivacaine
T0386L
Synonym: LEA-103 HCl
Target: Potassium Channel, Sodium Channel
Tipepidine hydrochloride
T13164
Synonym:
Target: Potassium Channel, Dopamine Receptor
Evifacotrep
T40042
Synonym:
Target: TRP/TRPV Channel
Flecainide hydrochloride
T8581
Synonym:
Target: Others
1-EBIO
T2604
Synonym:
Target: Calcium Channel
Flufenamic acid
T0858
Synonym: Arlef,Nichisedan,Achless
Target: Potassium Channel, Calcium Channel, Chloride channel, COX, AMPK, Parasite
Ropivacaine hydrochloride
T0386
Synonym: Ropivacaine monohydrochloride
Target: Potassium Channel, Sodium Channel
Erastin
T1765
Synonym:
Target: Ferroptosis, VDAC
Atpenin A5
T9714
Synonym:
Target: Potassium Channel
Clofilium tosylate
T14982
Synonym:
Target: Potassium Channel
SR33805
T8674
Synonym:
Target: Calcium Channel
AMTB hydrochloride
T19723
Synonym: AMTB
Target: TRP/TRPV Channel
1 2 3 4 5 ... 23
Cat No. Product Name Synonyms Targets
T0690 Quinine Potassium Channel , Platelet aggregation , Parasite
Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy has been associated with rare instances...
TN2322 Yangambin Calcium Channel , PAFR
Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibiti...
T7177 Capsazepine Apoptosis , TRP/TRPV Channel
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel. It is ...
T8189 Dihydroberberine Potassium Channel , HSP , HER
Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interacti...
T37709 2,2,2-Trichloroethanol Potassium Channel , Endogenous Metabolite
2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1]. 2,2,2-trichloroethanol activates a nonclassical ...
T6S1418 Praeruptorin C Antioxidant , Calcium Channel
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ...
T12514 Podocarpic acid Others , TRP/TRPV Channel
Podocarpic acid is a natural product and a novel TRPA1 activator.
TN1092 O-Nornuciferine Potassium Channel , HER
O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.
T4S1876 3-Deoxyaconitine Sodium Channel
3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the rele...
T8787 Drotaverine hydrochloride PDE
Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor，and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally rela...
T6S1684 8-Gingerol Antioxidant , Antibacterial , TRP/TRPV Channel
1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic...
T7210 Guanosine 5'-diphosphate GDP Endogenous Metabolite
Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.
T0728 Ethosuximide Zarontin Calcium Channel
Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other types of seizures.
T2807 Caffeic Acid Lipoxygenase , Endogenous Metabolite , TRP/TRPV Channel
Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities.
T3904 Gomisin J Calcium Channel , AMPK
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK...
T8206 Cycleanine Others
Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities.
T0801 Tannic acid Gallotannic acid Potassium Channel , HER , CXCR
Tannic acid (Gallotannic acid) is a novel hERG channel blocker.
T3S1873 Talatisamine Potassium Channel
1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talat...
T4590 (+)-Kavain Kavain,L-KAWAIN,(R)-KAWAIN Calcium Channel , GABA Receptor , Sodium Channel , Monoamine Transporter
(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
T5723 Menthol DL-Menthol Others , Calcium Channel
Menthol (DL-Menthol) is an organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local anesthetic properties.
T3054 Daurisoline (R,R)-Daurisoline Others , Potassium Channel , Autophagy
Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.
T1186 Ifenprodil Tartrate Potassium Channel , NMDAR , iGluR
Ifenprodil is a selective NMDA receptor (glutamate) antagonist.
T3A2467 Allocryptopine Thalictrimine,Fagarine I Potassium Channel
Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.
T15027 Cyclopiazonic acid Calcium Channel
Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A. flavus. Cyclopiazonic acid (CPA) is an endoplasmic reticulum calcium ATPase (Ca2+ATPase; SERCA)nanomolar inhibitor and a potent inducer of ce...
TN4417 Larixyl acetate Others
Larixyl acetate is a bioactive chemical.
TN1035 Irisolidone IL Receptor , NF-κB , Chloride channel
Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.
T8299 Dimethyl lithospermate B dmLSB Sodium Channel
Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist.
TQ0001 1,4-Cineole Isocineole Endogenous Metabolite , TRP/TRPV Channel
1,4-Cineole (Isocineole) is a natural, oxygenated monoterpene. 1,4-Cineole can activate both human TRPM8 and human TRPA1.
T2996 Tetrandrine NSC-77037,d-Tetrandrine,Hanfangchin A,Fanchinine,Sinomenine A Potassium Channel , Calcium Channel
Tetrandrine (Sinomenine A) is a natural, bis-benzylisoquinoline alkaloid isolated from the root of the plant. Tetrandrine non-selectively inhibits calcium channel activity and induces G1 blockade of the G1 phase of the c...
T7056 Dronedarone SR 33589 P450 , Potassium Channel , Calcium Channel , Sodium Channel , Adrenergic Receptor , AChR , Autophagy
Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
T4S1422 Praeruptorin E Others , Calcium Channel
1. Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those displayed by drugs that have calcium entry blocking activit...
T4333 Quinine dihydrochloride Quinine bimuriate Others
Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae). It is also an antimalarial and muscle relaxant (skeletal).
TMS2171 (±)-Naringenin Salipurpol,Naringenine,Naringenin Potassium Channel
(±)-Naringenin (Naringenine) is a natural product. It displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes.
TQ0302 Thapsigargin Apoptosis , SARS-CoV , Calcium Channel
Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigargin increases cytoplasmic calcium concentration by blocking ...
T7938 Quinidine Parasite
Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.
T3021 Bulleyaconitine A Bulleyaconi cine A Sodium Channel
Bulleyaconitine A (Bulleyaconi cine A), an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.
T3S0081 Oxypeucedanin (+-)-Oxypeucedanin,Oxypeucadanin Potassium Channel
1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocke...
T8182 Guanfu base A Guan-fu base A P450 , Potassium Channel , HER
Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.
T6856 Halofuginone Tempostatin,empostatin,RU-19110 Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
T3013 Catharanthine tartrate Catharanthine hemitartrate Others , Calcium Channel
Catharanthine tartrate (Catharanthine hemitartrate) is an alkaloid from periwinkle that inhibits voltage-gated L-type calcium channels and has antitumor and hypotensive activities.
T3876 Loureirin B PAI-1 , ERK , Potassium Channel , JNK
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathw...
T2952 Camphor (±)-Camphor,Bornan-2-one,2-Camphanone,2-Bornanone,Formosa Influenza Virus , TRP/TRPV Channel
Camphor (2-Camphanone) is a bicyclic monoterpene ketone found widely in plants, especially CINNAMOMUM CAMPHORA. It is used topically as a skin antipruritic and as an anti-infective agent.
T2782 Catharanthine (+)-3, 4-Didehydrocoronaridine,(+)-3,4-Didehydrocoronaridine Calcium Channel , AChR
Catharanthine ((+)-3,4-Didehydrocoronaridine) suppresses nicotinic receptor-mediated diaphragm contractions (IC50=59.6 μM).
T3727 Methyl syringate Syringic Acid Methyl Ester TRP/TRPV Channel
Methyl syringate (Syringic Acid Methyl Ester) has a unique inhibitory activity toward aflatoxin production with a different mode of action from that of gallic acid. Methyl syringate from K. pictus is a specific and selec...
TN1008 Psoralenoside CaMK , Calcium Channel , Histamine Receptor
Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity.
T3S0870 Paederosidic acid methyl ester ATPase , Potassium Channel , NO Synthase
Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.
TCS0102 Pulegone (+)-Pulegone Calcium Channel , Endogenous Metabolite , TRP/TRPV Channel
1. Pulegone ((+)-Pulegone) has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive psychostimulant effect t...
T6S1500 Ginsenoside Rf Ginsenoside-Rf,Panaxoside Rf Calcium Channel , Endogenous Metabolite
Ginsenoside Rf (Panaxoside Rf) is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channel.
T0928 L-Ascorbic acid Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,L-Ascorbate Apoptosis , Calcium Channel , Reactive Oxygen Species , Endogenous Metabolite
L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant. L-Ascorbic acid functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen. L-...
T3092 Nigericin sodium salt Potassium Channel , NOD-like Receptor (NLR) , Antibacterial , Antibiotic , NOD
Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which inhibits Golgi function and suppresses the growth of Gram-...
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Natural Products

Quinine
T0690
Synonym:
Target: Potassium Channel, Platelet aggregation, Parasite
Yangambin
TN2322
Synonym:
Target: Calcium Channel, PAFR
Capsazepine
T7177
Synonym:
Target: Apoptosis, TRP/TRPV Channel
Dihydroberberine
T8189
Synonym:
Target: Potassium Channel, HSP, HER
2,2,2-Trichloroethanol
T37709
Synonym:
Target: Potassium Channel, Endogenous Metabolite
Praeruptorin C
T6S1418
Synonym:
Target: Antioxidant, Calcium Channel
Podocarpic acid
T12514
Synonym:
Target: Others, TRP/TRPV Channel
O-Nornuciferine
TN1092
Synonym:
Target: Potassium Channel, HER
3-Deoxyaconitine
T4S1876
Synonym:
Target: Sodium Channel
Drotaverine hydrochloride
T8787
Synonym:
Target: PDE
8-Gingerol
T6S1684
Synonym:
Target: Antioxidant, Antibacterial, TRP/TRPV Channel
Guanosine 5'-diphosphate
T7210
Synonym: GDP
Target: Endogenous Metabolite
Ethosuximide
T0728
Synonym: Zarontin
Target: Calcium Channel
Caffeic Acid
T2807
Synonym:
Target: Lipoxygenase, Endogenous Metabolite, TRP/TRPV Channel
Gomisin J
T3904
Synonym:
Target: Calcium Channel, AMPK
Cycleanine
T8206
Synonym:
Target: Others
Tannic acid
T0801
Synonym: Gallotannic acid
Target: Potassium Channel, HER, CXCR
Talatisamine
T3S1873
Synonym:
Target: Potassium Channel
(+)-Kavain
T4590
Synonym: Kavain,L-KAWAIN,(R)-KAWAIN
Target: Calcium Channel, GABA Receptor, Sodium Channel, Monoamine Transporter
Menthol
T5723
Synonym: DL-Menthol
Target: Others, Calcium Channel
Daurisoline
T3054
Synonym: (R,R)-Daurisoline
Target: Others, Potassium Channel, Autophagy
Ifenprodil Tartrate
T1186
Synonym:
Target: Potassium Channel, NMDAR, iGluR
Allocryptopine
T3A2467
Synonym: Thalictrimine,Fagarine I
Target: Potassium Channel
Cyclopiazonic acid
T15027
Synonym:
Target: Calcium Channel
Larixyl acetate
TN4417
Synonym:
Target: Others
Irisolidone
TN1035
Synonym:
Target: IL Receptor, NF-κB, Chloride channel
Dimethyl lithospermate B
T8299
Synonym: dmLSB
Target: Sodium Channel
1,4-Cineole
TQ0001
Synonym: Isocineole
Target: Endogenous Metabolite, TRP/TRPV Channel
Tetrandrine
T2996
Synonym: NSC-77037,d-Tetrandrine,Hanfangchin A,Fanchinine,Sinomenine A
Target: Potassium Channel, Calcium Channel
Dronedarone
T7056
Synonym: SR 33589
Target: P450, Potassium Channel, Calcium Channel, Sodium Channel, Adrenergic Receptor, AChR, Autophagy
Praeruptorin E
T4S1422
Synonym:
Target: Others, Calcium Channel
Quinine dihydrochloride
T4333
Synonym: Quinine bimuriate
Target: Others
(±)-Naringenin
TMS2171
Synonym: Salipurpol,Naringenine,Naringenin
Target: Potassium Channel
Thapsigargin
TQ0302
Synonym:
Target: Apoptosis, SARS-CoV, Calcium Channel
Quinidine
T7938
Synonym:
Target: Parasite
Bulleyaconitine A
T3021
Synonym: Bulleyaconi cine A
Target: Sodium Channel
Oxypeucedanin
T3S0081
Synonym: (+-)-Oxypeucedanin,Oxypeucadanin
Target: Potassium Channel
Guanfu base A
T8182
Synonym: Guan-fu base A
Target: P450, Potassium Channel, HER
Halofuginone
T6856
Synonym: Tempostatin,empostatin,RU-19110
Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Catharanthine tartrate
T3013
Synonym: Catharanthine hemitartrate
Target: Others, Calcium Channel
Loureirin B
T3876
Synonym:
Target: PAI-1, ERK, Potassium Channel, JNK
Camphor
T2952
Synonym: (±)-Camphor,Bornan-2-one,2-Camphanone,2-Bornanone,Formosa
Target: Influenza Virus, TRP/TRPV Channel
Catharanthine
T2782
Synonym: (+)-3, 4-Didehydrocoronaridine,(+)-3,4-Didehydrocoronaridine
Target: Calcium Channel, AChR
Methyl syringate
T3727
Synonym: Syringic Acid Methyl Ester
Target: TRP/TRPV Channel
Psoralenoside
TN1008
Synonym:
Target: CaMK, Calcium Channel, Histamine Receptor
Paederosidic acid methyl ester
T3S0870
Synonym:
Target: ATPase, Potassium Channel, NO Synthase
Pulegone
TCS0102
Synonym: (+)-Pulegone
Target: Calcium Channel, Endogenous Metabolite, TRP/TRPV Channel
Ginsenoside Rf
T6S1500
Synonym: Ginsenoside-Rf,Panaxoside Rf
Target: Calcium Channel, Endogenous Metabolite
L-Ascorbic acid
T0928
Synonym: Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,L-Ascorbate
Target: Apoptosis, Calcium Channel, Reactive Oxygen Species, Endogenous Metabolite
Nigericin sodium salt
T3092
Synonym:
Target: Potassium Channel, NOD-like Receptor (NLR), Antibacterial, Antibiotic, NOD
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Recombinant Proteins

Species：
Human (68)
Mouse (14)
E. coli (4)
Rat (4)
H1N1 (3)
Androctonus australis (1)
Androctonus mauritanicus (1)
Bovine (1)
CHIKV (1)
Canine (1)
Expression System：
E. coli (69)
HEK293 (15)
in vitro E. coli expression system (11)
Yeast (5)
Baculovirus-Insect Cells (3)
Baculovirus (1)
Human Cells (1)
Tag：
His (21)
N-terminal 6xHis-tagged (21)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (16)
N-terminal 10xHis-tagged (10)
N-terminal 6xHis-SUMO-tagged (8)
hFc (4)
C-6His (3)
N-6His (3)
N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged (2)
N-terminal His-tagged/Tag-Free (2)
Cat No. Product Name Species Expression System
TMPY-03697 SCN2B Protein, Human, Recombinant (His) Human HEK293
SCN2B plays a key role in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. Voltage-gated sodium channels (NaV) are composed of one pore-forming alpha-subunit, which...
TMPJ-00719 CLIC3 Protein, Human, Recombinant (His) Human E. coli
Chloride intracellular channel protein 3 (CLIC3) is encoded by the CLIC3 gene. CLIC3 is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain and one GST ...
TMPJ-01363 CLIC5 Protein, Human, Recombinant (His) Human E. coli
Chloride Intracellular Channel Protein 5 (CLIC5) is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain. Chloride intracellular channels are involved in...
TMPY-04075 CLIC1 Protein, Human, Recombinant (His) Human E. coli
Members of the CLIC family are largely soluble proteins that possess the intriguing property of spontaneous insertion into phospholipid bilayers to form integral membrane ion channels. Chloride intracellular channel 1 (C...
TMPY-03615 CSEN Protein, Human, Recombinant (His) Human E. coli
KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3, also known as CSEN) is a Protein Coding gene. CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to th...
TMPY-03183 SCN2B Protein, Human, Recombinant (hFc) Human HEK293
SCN2B plays a key role in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. Voltage-gated sodium channels (NaV) are composed of one pore-forming alpha-subunit, which...
TMPJ-00666 CLIC2 Protein, Human, Recombinant (His) Human E. coli
Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells; it regulatescellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane in...
TMPH-02523 AQP2 Protein, Mouse, Recombinant (His) Mouse in vitro E. coli expression system
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential rol...
TMPH-03246 AQP2 Protein, Rat, Recombinant (His) Rat in vitro E. coli expression system
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential rol...
TMPH-01279 CRACR2B Protein, Human, Recombinant (His) Human E. coli
Plays a role in store-operated Ca(2+) entry (SOCE).
TMPH-02308 CACNA2D1 Protein, Human, Recombinant (His & SUMO) Human E. coli
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling.
TMPY-01890 CLIC4 Protein, Human, Recombinant (His) Human E. coli
Chloride intracellular channel protein 4, also known as Intracellular chloride ion channel protein p64H1 and CLIC4, is a member of the chloride channel CLIC family. It contains oneGST C-terminal domain. CLIC4 is a mem...
TMPH-00780 CACNA1C Protein, Guinea Pig, Recombinant (His) Guinea pig in vitro E. coli expression system
Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm...
TMPY-02976 SCN3B Protein, Human, Recombinant (His) Human HEK293
SCN3B (sodium channel, voltage-gated, type III, beta, human IgG1-Fc chimera) belongs to the sodium channel auxiliary subunit SCN3B family. It contains 1 Ig-like C2-type (immunoglobulin-like) domain. Voltage-gated sodium ...
TMPY-02722 SCN3B Protein, Human, Recombinant (hFc) Human HEK293
SCN3B (sodium channel, voltage-gated, type III, beta, human IgG1-Fc chimera) belongs to the sodium channel auxiliary subunit SCN3B family. It contains 1 Ig-like C2-type (immunoglobulin-like) domain. Voltage-gated sodium ...
TMPH-00952 Aquaporin-1/AQP1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Aquaporin-1/AQP1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02980 Aquaporin-4/AQP4 Protein, Mouse, Recombinant (His) Mouse Yeast
Forms a water-specific channel. Plays an important role in brain water homeostasis and in glymphatic solute transport. Required for a normal rate of water exchange across the blood brain interface. Required for normal le...
TMPH-00953 Aquaporin-4/AQP4 Protein, Human, Recombinant (His & SUMO) Human E. coli
Aquaporin-4/AQP4 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00580 Aquaporin Z Protein, E. coli, Recombinant (His) E. coli in vitro E. coli expression system
Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid...
TMPH-03209 CLNS1A Protein, Rabbit, Recombinant (His & Myc) Rabbit E. coli
Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins. Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blo...
TMPY-01756 Transthyretin Protein, Human, Recombinant (His) Human HEK293
Prealbumin/Transthyretin, also known as ATTR, Prealbumin, TTR and PALB, is a secreted and cytoplasm protein that belongs to the Prealbumin / Transthyretin family. Prealbumin / Transthyretin is detected in serum and cereb...
TMPH-02309 KCNAB2 Protein, Human, Recombinant (His & SUMO) Human E. coli
Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability. Promotes expressi...
TMPH-01300 Stomatin/STOM Protein, Human, Recombinant (His & SUMO) Human E. coli
Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.
TMPH-02331 GLRA1 Protein, Human, Recombinant (His & Myc) Human E. coli
Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and beta-alanine. Channel characteristics depend on the subunit co...
TMPH-01394 GRIN1 Protein, Human, Recombinant (His) Human E. coli
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the ...
TMPH-01009 RHD Protein, Human, Recombinant (GST & His) Human E. coli
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
TMPH-01890 KCNA1 Protein, Human, Recombinant (His) Human E. coli
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the kidney. Contributes to the regulation of the ...
TMPH-01609 LGI1 Protein, Human, Recombinant (His & Myc) Human E. coli
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regula...
TMPH-00670 MscL Protein, E. coli O157:H7, Recombinant (B2M & His) E. coli E. coli
Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
TMPH-01891 KCNE2 Protein, Human, Recombinant (His) Human in vitro E. coli expression system
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled wit...
TMPH-00873 CHRNG Protein, Human, Recombinant (His) Human Yeast
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
TMPH-02336 TAS2R10 Protein, Human, Recombinant (His & KSI) Human E. coli
Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
TMPH-01762 CHRNA3 Protein, Human, Recombinant (His & Myc & SUMO) Human E. coli
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
TMPH-02486 CHRNA1 Protein, Mouse, Recombinant (E. coli, His) Mouse E. coli
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
TMPH-00871 CHRNA1 Protein, Human, Recombinant (His) Human E. coli
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
TMPH-01887 Polycystin-1 Protein, Human, Recombinant (His) Human E. coli
Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Both PKD1 and PKD2 are required for channel...
TMPH-00874 CHRNG Protein, Human, Recombinant (E. coli, His) Human E. coli
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
TMPH-00872 CHRNE Protein, Human, Recombinant (His & Myc) Human E. coli
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
TMPH-02487 CHRNA1 Protein, Mouse, Recombinant (His) Mouse Yeast
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
TMPH-00818 Delta-theraphotoxin-Hm1a Protein, Heteroscodra maculata, Recombinant (His & Myc & SUMO) Heteroscodra maculata E. coli
Gating-modifier toxin that potently inhibits inactivation of the mammalian Nav1.1/SCN1A sodium channel (EC(50)=38 nM). Also moderately inhibits inactivation of Nav1.2/SCN2A (EC(50)=236 nM) and Nav1.3/SCN3A (EC(50)=220 nM...
TMPH-01763 CHRNB2 Protein, Human, Recombinant (His & V5) Human E. coli
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions.
TMPH-00054 AaH II Protein, Androctonus australis, Recombinant (His & SUMO) Androctonus australis E. coli
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. The toxin principally slows the inactivation proc...
TMPH-01027 CAMK2D Protein, Human, Recombinant (His) Human E. coli
Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in C...
TMPH-00596 Colicin-E1 Protein, E. coli, Recombinant (Cell-Free, His & Myc) E. coli in vitro E. coli expression system
This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.; Colicins are polypeptide toxins produced by and active agains...
TMPH-00597 Colicin-E1 Protein, E. coli, Recombinant (His & Myc) E. coli E. coli
This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.; Colicins are polypeptide toxins produced by and active agains...
TMPH-01367 GABRB2 Protein, Human, Recombinant (His) Human E. coli
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain. Plays an important role in the formation of functional inhibitory GABAergi...
TMPH-02905 TRPC1 Protein, Mouse, Recombinant (His) Mouse in vitro E. coli expression system
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled recep...
TMPH-00362 Beta-mammal toxin Css4 Protein, Centruroides suffusus, Recombinant (His & SUMO) Centruroides suffusus E. coli
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repe...
TMPH-01889 KCNK3 Protein, Human, Recombinant (His & Myc) Human in vitro E. coli expression system
pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassi...
TMPH-01393 GRIA3 Protein, Human, Recombinant (His & SUMO) Human E. coli
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many ...
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SCN2B Protein, Human, Recombinant (His)
TMPY-03697
Species: Human
Expression System: HEK293
CLIC3 Protein, Human, Recombinant (His)
TMPJ-00719
Species: Human
Expression System: E. coli
CLIC5 Protein, Human, Recombinant (His)
TMPJ-01363
Species: Human
Expression System: E. coli
CLIC1 Protein, Human, Recombinant (His)
TMPY-04075
Species: Human
Expression System: E. coli
CSEN Protein, Human, Recombinant (His)
TMPY-03615
Species: Human
Expression System: E. coli
SCN2B Protein, Human, Recombinant (hFc)
TMPY-03183
Species: Human
Expression System: HEK293
CLIC2 Protein, Human, Recombinant (His)
TMPJ-00666
Species: Human
Expression System: E. coli
AQP2 Protein, Mouse, Recombinant (His)
TMPH-02523
Species: Mouse
Expression System: in vitro E. coli expression system
AQP2 Protein, Rat, Recombinant (His)
TMPH-03246
Species: Rat
Expression System: in vitro E. coli expression system
CRACR2B Protein, Human, Recombinant (His)
TMPH-01279
Species: Human
Expression System: E. coli
CACNA2D1 Protein, Human, Recombinant (His & SUMO)
TMPH-02308
Species: Human
Expression System: E. coli
CLIC4 Protein, Human, Recombinant (His)
TMPY-01890
Species: Human
Expression System: E. coli
CACNA1C Protein, Guinea Pig, Recombinant (His)
TMPH-00780
Species: Guinea pig
Expression System: in vitro E. coli expression system
SCN3B Protein, Human, Recombinant (His)
TMPY-02976
Species: Human
Expression System: HEK293
SCN3B Protein, Human, Recombinant (hFc)
TMPY-02722
Species: Human
Expression System: HEK293
Aquaporin-1/AQP1 Protein, Human, Recombinant (His & SUMO)
TMPH-00952
Species: Human
Expression System: E. coli
Aquaporin-4/AQP4 Protein, Mouse, Recombinant (His)
TMPH-02980
Species: Mouse
Expression System: Yeast
Aquaporin-4/AQP4 Protein, Human, Recombinant (His & SUMO)
TMPH-00953
Species: Human
Expression System: E. coli
Aquaporin Z Protein, E. coli, Recombinant (His)
TMPH-00580
Species: E. coli
Expression System: in vitro E. coli expression system
CLNS1A Protein, Rabbit, Recombinant (His & Myc)
TMPH-03209
Species: Rabbit
Expression System: E. coli
Transthyretin Protein, Human, Recombinant (His)
TMPY-01756
Species: Human
Expression System: HEK293
KCNAB2 Protein, Human, Recombinant (His & SUMO)
TMPH-02309
Species: Human
Expression System: E. coli
Stomatin/STOM Protein, Human, Recombinant (His & SUMO)
TMPH-01300
Species: Human
Expression System: E. coli
GLRA1 Protein, Human, Recombinant (His & Myc)
TMPH-02331
Species: Human
Expression System: E. coli
GRIN1 Protein, Human, Recombinant (His)
TMPH-01394
Species: Human
Expression System: E. coli
RHD Protein, Human, Recombinant (GST & His)
TMPH-01009
Species: Human
Expression System: E. coli
KCNA1 Protein, Human, Recombinant (His)
TMPH-01890
Species: Human
Expression System: E. coli
LGI1 Protein, Human, Recombinant (His & Myc)
TMPH-01609
Species: Human
Expression System: E. coli
MscL Protein, E. coli O157:H7, Recombinant (B2M & His)
TMPH-00670
Species: E. coli
Expression System: E. coli
KCNE2 Protein, Human, Recombinant (His)
TMPH-01891
Species: Human
Expression System: in vitro E. coli expression system
CHRNG Protein, Human, Recombinant (His)
TMPH-00873
Species: Human
Expression System: Yeast
TAS2R10 Protein, Human, Recombinant (His & KSI)
TMPH-02336
Species: Human
Expression System: E. coli
CHRNA3 Protein, Human, Recombinant (His & Myc & SUMO)
TMPH-01762
Species: Human
Expression System: E. coli
CHRNA1 Protein, Mouse, Recombinant (E. coli, His)
TMPH-02486
Species: Mouse
Expression System: E. coli
CHRNA1 Protein, Human, Recombinant (His)
TMPH-00871
Species: Human
Expression System: E. coli
Polycystin-1 Protein, Human, Recombinant (His)
TMPH-01887
Species: Human
Expression System: E. coli
CHRNG Protein, Human, Recombinant (E. coli, His)
TMPH-00874
Species: Human
Expression System: E. coli
CHRNE Protein, Human, Recombinant (His & Myc)
TMPH-00872
Species: Human
Expression System: E. coli
CHRNA1 Protein, Mouse, Recombinant (His)
TMPH-02487
Species: Mouse
Expression System: Yeast
Delta-theraphotoxin-Hm1a Protein, Heteroscodra maculata, Recombinant (His & Myc & SUMO)
TMPH-00818
Species: Heteroscodra maculata
Expression System: E. coli
CHRNB2 Protein, Human, Recombinant (His & V5)
TMPH-01763
Species: Human
Expression System: E. coli
AaH II Protein, Androctonus australis, Recombinant (His & SUMO)
TMPH-00054
Species: Androctonus australis
Expression System: E. coli
CAMK2D Protein, Human, Recombinant (His)
TMPH-01027
Species: Human
Expression System: E. coli
Colicin-E1 Protein, E. coli, Recombinant (Cell-Free, His & Myc)
TMPH-00596
Species: E. coli
Expression System: in vitro E. coli expression system
Colicin-E1 Protein, E. coli, Recombinant (His & Myc)
TMPH-00597
Species: E. coli
Expression System: E. coli
GABRB2 Protein, Human, Recombinant (His)
TMPH-01367
Species: Human
Expression System: E. coli
TRPC1 Protein, Mouse, Recombinant (His)
TMPH-02905
Species: Mouse
Expression System: in vitro E. coli expression system
Beta-mammal toxin Css4 Protein, Centruroides suffusus, Recombinant (His & SUMO)
TMPH-00362
Species: Centruroides suffusus
Expression System: E. coli
KCNK3 Protein, Human, Recombinant (His & Myc)
TMPH-01889
Species: Human
Expression System: in vitro E. coli expression system
GRIA3 Protein, Human, Recombinant (His & SUMO)
TMPH-01393
Species: Human
Expression System: E. coli
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Cat No. Product Name
L7300 Potassium Channel Blocker Library

160 compounds
A unique collection of 160 potassium channel blockers and agonists for high throughput and high content screening;
L2300 Ion Channel Inhibitor Library

946 compounds
A unique collection of 946 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
L7400 Sodium Channel Blocker Library

128 compounds
A unique collection of 128 sodium channel blockers and agonists for high throughput and high content screening;
L7200 Calcium Channel Compound Library

143 compounds
A unique collection of 143 calcium channel blockers and agonists for high throughput and high content screening;
L2800 Serotonin Receptor-Targeted Compound Library

275 compounds
A unique collection of 275 compounds targeting serotonin receptors for high throughput screening and high content screening;
L9600 Peptide Compound Library

800 compounds
800 peptides can be used in peptide drug development and signaling transduction and mechanism study;

Libraries

Potassium Channel Blocker Library
L7300
Compounds: 160
Ion Channel Inhibitor Library
L2300
Compounds: 946
Sodium Channel Blocker Library
L7400
Compounds: 128
Calcium Channel Compound Library
L7200
Compounds: 143
Serotonin Receptor-Targeted Compound Library
L2800
Compounds: 275
Peptide Compound Library
L9600
Compounds: 800
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