alternaria solani

Chlorothalonil (DAC 2787) is a broad-spectrum fungicide with high efficiency and low toxicity. Chlorothalonil is widely used to control various pests such as fruit trees and vegetable leaves. Chlorothalonil also has good control effects on various diseases such as rice, wheat, and cotton.

Antifungalagent 134 (Compound B13) is an antifungal agent effective against Botrytis cinerea, Alternaria solani, Fusarium graminearum, Rhizoctonia solani, Colletotrichum orbiculare, and Alternaria alternata with EC50 values of 3.24, 1.89, 1.70, 0.36, 4.27, and 1.50 μg/mL, respectively. It disrupts the fungal cell membranes and mitochondria, leading to substantial accumulation of reactive oxygen species (ROS). Additionally, Antifungalagent 134 exhibits significant herbicidal activity on field weeds such as Amaranthus retroflexus L and Abutilon theophrasti Medicus, and is applicable in crop disease and field weed research.

N-Heptyl 4-hydroxybenzoate (p-Oxybenzoesaureheptylester) acts as an antimicrobial agent, inhibiting Staphylococcus aureus with a minimum inhibitory concentration (MIC) of 12.5 μg/mL. Additionally, it is effective against plant pathogenic fungi, such as Alternaria brassicicola, Fusarium solani, Colletotrichum dematium, and Colletotrichum acutatum.

Stemphyperylenol exhibits potent antifungal activity against Alternaria solani, a plant pathogen, with a minimum inhibitory concentration (MIC) value of 1.57 μM.

Fluopyram is an orally active succinate dehydrogenase inhibitor with antifungal and nematicidal properties. It suppresses succinate dehydrogenase activity, activates the CAR and PXR nuclear receptors, and elevates caspase-3, TNF-α, and NF-κB levels. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea, and Alternaria solani, with EC₅₀ values of 3.35, 5.389, and 0.244 µg/mL, respectively. It has been associated with liver and thyroid tumor formation and exhibits nephrotoxic and embryotoxic effects.

Eucalyptacid A, a metabolite with antifungal properties, demonstrates efficacy against Alternaria solani, displaying minimum inhibitory concentrations (MIC) ranging between 6.25 and 50 μM [1].

Cytosporone C, an antifungal metabolite produced by the Diaporthe eucalyptorum fungus associated with Melia azedarach, demonstrates antifungal efficacy against Alternaria solani [1].

Chaetosemin J, a metabolite with antifungal properties, effectively inhibits the growth of plant pathogenic fungi including Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, demonstrating minimum inhibitory concentration (MIC) values between 12.5-25 μM [1].

Eugenitol (Compound 3), an antifungal metabolite extracted from Diaporthe eucalyptorum, exhibits inhibitory properties against four plant pathogenic fungi: Alternaria solani, Botrytis cinerea, Fusarium solani, and Gibberella saubinettii [1].

Calycanthine is a natural alkaloid exhibiting central nervous system toxicity, capable of inducing convulsions and seizures.