acridine

Acridine is a classic fluorescent pH indicator that combines stability and fluorescence properties. Its tricyclic conjugated molecular structure can achieve pH response. In different pH environments, Acridine molecules undergo protonation or deprotonation transformations, and this structural change significantly alters their fluorescence properties.

Acridine, 1-azido- is a bioactive chemical.

Acridine, 2,6-diamino- is a high-purity biochemical reagent used in biochemical experiments and drug synthesis research.

Acridine, 2,7-diamino-, hydrochloride is a bioactive chemical.

Acridine-9-carboxamide, 1,2,3,5-tetrahydro-N,N-diethyl- is a biochemcial.

Sarcolysine acridine is a bioactive chemical.

Acridine-9-carboxaldehyde is an acridine derivative that functions as a pH indicator for fluorescence lifetime measurements.

Proflavine hydrochloride (acridine-3,6-diamine hydrochloride) serves as both a preservative and an antimicrobial agent.

Acridine-9-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T65511 and the CAS number is 5336-90-3.

Acridine Homodimer (NSC 219743), also known as acridine dimer, serves as a fluorescent dye that exhibits blue-green fluorescence upon binding to DNA. This compound demonstrates a significantly high affinity for AT-rich regions within nucleic acids, enabling its application in chromosome banding [1].

2-Methyl-1,2,3,4-tetrahydro-acridine-9-carboxylic acid ,with CAS No. 247571-77-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Methyl-1,2,3,4-tetrahydro-acridine-9-carboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Pyrazoloacridine (PD 115934) is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 μM in K562 cells. Pyrazoloacridine shows anti-cancer activity.

Ethacridine lactate hydrate is a topically applied anti-infective agent.

Ethacridine lactate (Acrinol) is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.

1,8(2H,5H)-acridinedione, 3,4,6,7-tetrahydro- ,with CAS No. 56798-21-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1,8(2H,5H)-acridinedione, 3,4,6,7-tetrahydro- provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.

(-)-Lunacridine is a bioactive chemical.

(+/-)-Lunacridine is a bioactive chemical.

2-Acridinesulfonic acid is a biochemical.

4-Aminoacridine is an aminoacridine

Lunacridine perchlorate isa bioactive chemical.

6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids that possess radical scavenging, amyloid-β aggregation inhibitory, and/or β-secretase 1 (BACE1) inhibitory activities in addition to their activity as AChE inhibitors.2,3 1.Recanatini, M., Cavalli, A., Belluti, F., et al.SAR of 9-amino-1,2,3,4-tetrahydroacridine-based acetylcholinesterase inhibitors: Synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analoguesJ. Med. Chem.43(10)2007-2018(2000) 2.Digiacomo, M., Chen, Z., Wang, S., et al.Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of ADBioorg. Med. Chem. Lett.25(4)807-810(2015) 3.Li, S.Y., Jiang, N., Xie, S.S., et al.Design, synthesis and evaluation of novel tacrine-rhein hybrids as multifunctional agents for the treatment of Alzheimer's diseaseOrg. Biomol. Chem.12(5)801-814(2014)

Octahydroaminoacridine, a Tacrine analogue, acts as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). It is applicable in Alzheimer's disease (AD) research [1].

Ethacridine acts as an inhibitor of poly (ADP-ribose) glycohydrolase (PARG) and functions as an activator of transcriptional coactivators. It induces apoptosis in thyroid cancer cells and promotes the differentiation of thyroid follicular cells.