acridine

Acridine-9-carboxaldehyde (Acridine-9-carbaldehyde) is a biologically active compound known for its potential antibacterial and antitumor activities. It is extensively utilized as a building block in compound development to synthesize a variety of biologically active derivatives. Additionally, Acridine-9-carboxaldehyde exhibits significant cytotoxicity against certain cancer cells, making it a vital candidate in cancer inhibition research.

Acridine, 1-azido- is a bioactive chemical.

Acridine, 2,6-diamino- (8CI) is a biochemical.

Acridine, 2,7-diamino-, hydrochloride is a bioactive chemical.

Acridine-9-carboxamide, 1,2,3,5-tetrahydro-N,N-diethyl- is a biochemcial.

Sarcolysine acridine is a bioactive chemical.

Acridine-9-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T65511 and the CAS number is 5336-90-3.

Acridine Homodimer (NSC 219743), also known as acridine dimer, serves as a fluorescent dye that exhibits blue-green fluorescence upon binding to DNA. This compound demonstrates a significantly high affinity for AT-rich regions within nucleic acids, enabling its application in chromosome banding [1].

Pyrazoloacridine (PD 115934) is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 μM in K562 cells. Pyrazoloacridine shows anti-cancer activity.

Ethacridine lactate hydrate is a topically applied anti-infective agent.

Ethacridine lactate (Acrinol) is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.

Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.

(-)-Lunacridine is a bioactive chemical.

(+/-)-Lunacridine is a bioactive chemical.

2-Acridinesulfonic acid is a biochemical.

4-Aminoacridine is an aminoacridine

Lunacridine perchlorate isa bioactive chemical.

6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids that possess radical scavenging, amyloid-β aggregation inhibitory, and/or β-secretase 1 (BACE1) inhibitory activities in addition to their activity as AChE inhibitors.2,3 1.Recanatini, M., Cavalli, A., Belluti, F., et al.SAR of 9-amino-1,2,3,4-tetrahydroacridine-based acetylcholinesterase inhibitors: Synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analoguesJ. Med. Chem.43(10)2007-2018(2000) 2.Digiacomo, M., Chen, Z., Wang, S., et al.Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of ADBioorg. Med. Chem. Lett.25(4)807-810(2015) 3.Li, S.Y., Jiang, N., Xie, S.S., et al.Design, synthesis and evaluation of novel tacrine-rhein hybrids as multifunctional agents for the treatment of Alzheimer's diseaseOrg. Biomol. Chem.12(5)801-814(2014)

Octahydroaminoacridine, a Tacrine analogue, acts as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). It is applicable in Alzheimer's disease (AD) research [1].

Ethacridine acts as an inhibitor of poly (ADP-ribose) glycohydrolase (PARG) and functions as an activator of transcriptional coactivators. It induces apoptosis in thyroid cancer cells and promotes the differentiation of thyroid follicular cells.

9,9-Dimethyl-9,10-dihydroacridine is a fused heterocyclic compound widely used in biochemical experiments and drug synthesis research.

9,10-Dihydroacridine is a fused heterocyclic compound widely used in biochemical experiments and drug synthesis research.

SKF96067 is a reversible gastric H+ K+-ATPase inhibitor that can induce relaxation of human airway smooth muscle in vitro.