acidic

1-Dodecylimidazole (N-Dodecylimidazole) is a chemical compound that acts as a cytotoxic agent and lysosomotropic detergent, inducing cell death through acid-dependent lysosomal accumulation, disrupting the lysosomal membrane, and releasing cysteine proteases into the cytoplasm. It also exhibits hypocholesterolemic and broad-spectrum antifungal activities.

4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside used for detecting α-galactosidase activity. The amount of released pNP increases significantly when PNP-alpha-D-Gal is used as a substrate.

1O14 is an ionizable lipid. Its ability to form unstable non-bilayer structures at acidic pH is crucial for endosomal escape and RNA cytosolic delivery. 1O14 is applicable in the preparation of liposomes.

IAJD93 is an ionizable lipid. Its ability to form unstable non-bilayer structures at acidic pH is crucial for endosomal escape and RNA delivery into the cytosol. IAJD93 can be utilized in the preparation of liposomes.

IAJD249 is an ionizable lipid. This type of lipid is crucial for endosomal escape and the delivery of RNA into the cytosol, due to its ability to form unstable non-bilayer structures at acidic pH. IAJD249 is also utilized in the preparation of liposomes.

Al-28 is an ionizable lipid that plays a crucial role in endosomal escape and RNA cytosol delivery by forming unstable non-bilayer structures at acidic pH. This compound is utilized in the preparation of liposomes.

L16 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is crucial for endosomal escape and RNA cytosolic delivery. L16 can be utilized in liposome preparation.

306Oi9-cis2 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is crucial for endosomal escape and RNA cytosolic delivery. 306Oi9-cis2 is utilized in the preparation of liposomes.

RM 137-15 is an ionizable lipid. Its ability to form unstable non-bilayer structures under acidic pH is crucial for endosomal escape and RNA cytosol delivery. RM 137-15 is utilized in the preparation of liposomes.

DSPE-PEG1000-TH is a PEG compound composed of DSPE and a pH-responsive cell-penetrating peptide (TH). In acidic environments, such as the tumor microenvironment, TH is activated, enabling the selective delivery of small molecules, oligonucleotides, proteins, and other agents into tumor cells.

DSPE-PEG5000-TH is a PEG compound formed from DSPE and the pH-responsive cell-penetrating peptide (TH). In acidic environments like the tumor microenvironment, TH is activated, allowing it to selectively deliver small molecules, oligonucleotides, proteins, and similar substances into tumor cells.

DSPE-PEG2000-TH is a PEG conjugate made from DSPE and a pH-responsive cell-penetrating peptide (TH). In acidic environments—such as the tumor microenvironment—TH becomes activated, allowing for the selective delivery of small molecules, oligonucleotides, and proteins into tumor cells.

Dicyclohexano-18-crown-6-ether can selectively extract lysine-rich cytochrome c protein from other cationic proteins under mild acidic and neutral conditions, demonstrating the specificity of ligand-protein interactions.

Sodium sesquicarbonate hydrate is a compound with buffering activity, capable of stabilizing pH by neutralizing acidic substances without causing drastic changes. This characteristic makes it widely used in various fields, particularly notable for its effectiveness in maintaining acid-base balance within biological systems.

Sodium carboxymethyl cellulose (CMC-Na) (MW 250000) is the sodium salt of carboxymethyl cellulose. In acidic media, it exhibits adsorption properties and acts as a corrosion inhibitor for low carbon steel. Additionally, sodium carboxymethyl cellulose functions as a thickener, paste, and barrier agent.

SoyPolysaccharides is a multifunctional biochemical reagent that is non-toxic, hydrophilic and biodegradable, and is suitable for a variety of scenarios in the food industry. It can not only be used as a thickener and emulsifier in beverages, sauces and dairy products, but also as a dietary fiber component. In addition, it exhibits excellent stability in oil/water emulsion systems, especially under acidic conditions, and can effectively prevent flocculation of β-conglycinin-based emulsions.

Naphthol AS-BI phosphate serves as both an acidic and alkaline phosphatase substrate, suitable for use in fluorescence assays. It is also utilized as a biomaterial or organic compound relevant to life science research.

Naphthol AS phosphate, 99% (TLC) (3-Hydroxy-2-naphthanilide phosphate, 99% (TLC)), serves as a histochemical substrate for both acidic and alkaline phosphatases.

Reinecke (Diamino-tetraisothiocyanato-chromium) is an ammonium salt. It is involved in the quantitative precipitation of basic compounds found in histones and acidic tissue extracts by forming Reinecke complexes.

1-O-Methyl-2-deoxy-D-ribose is a ribose derivative that facilitates the synthesis of 2-deoxy-D-ribose by introducing a methoxy protecting group at the anomeric carbon through a one-step reaction under acidic conditions. This compound can be utilized in research focused on the synthesis of chemical materials.

tert-Butyl (2-(pyridin-2-yldisulfanyl)ethyl)carbamate consists of a tert-butyl group, with an amine that can be deprotected under mild acidic conditions. The other part of the molecule functions as a thiol-specific labeling agent, commonly utilized for reversible binding to cysteine residues on proteins.

N4,N9-di-Boc-spermine is a spermine linker characterized by two Boc-protected amine groups and two additional amine groups. The Boc groups can be removed under mild acidic conditions to yield free amines. These amino groups can react with carboxylic acids, activated NHS esters, and carbonyl compounds (ketones, aldehydes). Spermidine, a polyamine, plays a role in regulating various cellular activities including cell growth and differentiation, DNA stability, and apoptosis.

N1,N12-Di-Boc-spermine is a spermine derivative that contains two Boc-protected amino groups. The Boc groups can be removed under mild acidic conditions to yield free amines. Spermidine, a related polyamine, plays a role in regulating diverse cellular processes, such as cell growth and differentiation, DNA stability, and apoptosis.

tert-Butyl methyl adipate is a compound that contains both a methyl ester group and a tert-butyl ester linkage. The methyl ester group can undergo hydrolysis, reduction, or substitution under various conditions. Additionally, the tert-butyl protected carboxylic acid can be deprotected in acidic environments.