vitronectin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T80859	Vitronectin
	Vitronectin, a multifunctional glycoprotein found in blood and the extracellular matrix, interacts with glycosaminoglycans, collagen, plasminogen, and the urokinase-receptor, in addition to stabilizing the inhibitory con...
T38603	Vitronectin (367-378)
	Vitronectin (367-378) is a peptide derived from residues 367-378 of the multifunctional glycoprotein known as Vitronectin. Vitronectin plays a pivotal role in cell growth, angiogenesis, and metastasis within various huma...
T2494	Cilengitide	EMD 121974	Integrin , Autophagy
	Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.		Integrin , Autophagy
TP1879L1	P11 acetate		Integrin
	P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).		Integrin
TP1736L	Fibrinogen-Binding Peptide 137235-80-4(fb-acetate)		Others
	Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits ...		Others
T76844	Abciximab	C7E3	Integrin
	Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor. Abciximab has anti-platelet aggregation and leukocyte adhesion, acting by binding to glycoproteins IIb/IIIa...		Integrin
T24796	SK&F 107260	Skf107260,Skf-107260,Skf 107260
	SK&F 107260 is an RGD-containing peptide. It is a potent GP IIb/IIIa antagonist and a vitronectin antagonist.
TP1879	HSDVHK-NH2	P11
	Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.
T14347	Aureothricin		Antibacterial
	Aureothricin, a dithiolopyrrolone (DTP) antibiotic originally derived from Streptomyces, demonstrates a broad-spectrum of antibacterial effectiveness. Additionally, it inhibits the adhesion of human umbilical vein endoth...		Antibacterial
TP1736	Fibrinogen-Binding Peptide
	Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen, a soluble plasma protein, is a cofactor in pl...
T75835	HSDVHK-NH2 TFA
	HSDVHK-NH2 TFA acts as an antagonist to the αvβ3-vitronectin integrin interaction, displaying an inhibitory concentration (IC 50) of 1.74 pg/mL (2.414 pM) [1] [2].
T82919	Batifiban TFA
	Batifiban TFA, a cyclic peptide and antagonist of the platelet glycoprotein GPⅡb/Ⅲa, inhibits platelet aggregation by blocking the binding of circulating vitronectin to integrin ανβ3 [1].
TN5221	(-)-Variabilin
	Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3....
T38363	MeOSuc-AAPV-pNA
	Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neut...
T83848	VnP-16 TFA
	VnP-16, a synthetic peptide fragment mirroring amino acids 270-281 of vitronectin (a multifunctional glycoprotein involved in cell attachment, migration, and spreading), promotes attachment and spreading of isolated huma...
T83736	RTDLDSLRTYTL TFA
	RTDLDSLRTYTL is a ligand for αVβ6 integrin, exhibiting selective inhibition of fibronectin's binding to αVβ6 integrin with considerably less effect on the interactions between vitronectin and αVβ3 or αVβ5, as well as fib...
T70368	SF0166
	SF0166 is a potent, selective antagonist of α v β 3, demonstrating IC 50 values of 0.6 nM for α v β 3, 8 nM for α v β 6, and 13 nM for α v β 8. It effectively inhibits cellular adhesion to vitronectin in human, rat, rabb...