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SIRT5 inhibitor 1

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
SIRT5 inhibitor 1
T129212166487-21-2In house
SIRT5 inhibitor 1 is a potent and selective inhibitor of human Sirtuin 5 deacylase (IC50: 0.11 μM) and is associated with aging-related diseases.
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6-8weeks
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SIRT5 inhibitor 7
T788032951090-00-7
SIRT5 inhibitor 7 (compound 58), a substrate-competitive and selective SIRT5 inhibitor with IC 50 = 310 nM, significantly attenuated renal dysfunction and pathological damage in lipopolysaccharide (LPS)- and cecum ligation perforation (CLP)-induced septic AKI mice, and modulated proteinsuccinimidylation and proinflammatory cytokine release and pro-inflammatory cytokine release in the kidneys of acute kidney injury (AKI) mice.
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8-10 weeks
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SIRT5 inhibitor 5
T726372883730-60-5
SIRT5 Inhibitor 5 is a potent substrate-competitive inhibitor of SIRT5, exhibiting an IC50 of 0.21 µM, and does not interact with the NAD+-binding pocket [1].
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6-8 weeks
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