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Orthopoxvirus

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    33
    TargetMol | Inhibitors_Agonists
  • Natural Products
    6
    TargetMol | Natural_Products
  • Recombinant Protein
    4
    TargetMol | Recombinant_Protein
Rifampicin
Rimactane, Rifamycin AMP, Rifampin
T068113292-46-1
Rifampicin (Rifamycin AMP) is a broad-spectrum antibiotic. Rifampicin has a strong antibacterial effect against Mycobacterium tuberculosis and is also effective against gram-positive and gram-negative bacteria and viruses.
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Ribavirin
Tribavirin, RTCA, NSC-163039, ICN-1229
T068436791-04-5
Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.
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Cytarabine
Cytosine β-D-arabinofuranoside, Cytosine Arabinoside, Ara-C, Arabinocytidine
T1272147-94-4
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity.
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Amantadine hydrochloride
Symmetrel, CI-719, Amantadine HCl, 1-Adamantylamine hydrochloride, 1-Adamantanamine hydrochloride, 1-adamantanamine HCl
T1406665-66-7
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.
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Trifluridine
Viroptic, Trifluridina, Trifluorothymidine, NSC 75520, NSC 529182, 5-Trifluorothymidine
T142870-00-8
Trifluridine (NSC-75520) is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity.
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Vidarabine
Vira-A, Arabinosyladenine, Ara-A, Adenine Arabinoside, 9-β-D-Arabinofuranosyladenine
T15065536-17-4
Vidarabine (Adenine Arabinoside) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the VACCINIA VIRUS and varicella zoster virus.
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Phosphonoacetic acid
T47294408-78-0
Phosphonoacetate, also known as fosfonet or phosphonacetic acid, belongs to the class of organic compounds known as organic phosphonic acids.Within the cell, phosphonoacetate is primarily located in the cytoplasm. Phosphonoacetate can be biosynthesized fr
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Levofloxacin
Tavanic, Levaquin, Fluoroquinolone, Cravit, (-)-Ofloxacin
T6567100986-85-4
Levofloxacin ((-)-Ofloxacin) is a synthetic fluoroquinolone antibiotic that inhibits the superhelical activity of bacterial DNA rotamase and prevents DNA replication. Levofloxacin is a broad-spectrum antibiotic used for the treatment of a wide range of bacterial infections.
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Mitoxantrone
mitozantrone
T658865271-80-9
Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.
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Canertinib
PD-183805, CI-1033
T6136267243-28-7
Canertinib (CI-1033) is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. Canertinib treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET.
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Alovudine
3'-Deoxy-3'-fluorothymidine
T468325526-93-6
Alovudine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and is a better biomarker in pancreatic cancer.
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Cidofovir
HPMPC, GS 0504, (S)-HPMPC
T6244113852-37-2
Cidofovir ((S)-HPMPC) inhibits virus replication by specific inhibition of viral DNA synthesis.
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3-Deazaneplanocin A
DZNep, 3-Deazaneplanocin
T6292102052-95-9
3-Deazaneplanocin A (DZNep) is a dual inhibitor of histone methyltransferase (EZH2) and S-adenosylhomocysteine hydrolase (AHCY) with antipoxidative activity that inhibits hepatic, renal, peritoneal, and airway fibrosis by inducing proteasomal degradation of its targets and reducing toxicity in animal models.
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7-10 days
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Clevudine
L-FMAU, Levovir
T6446163252-36-6
Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DNA (cccDNA), therefore the patient is less likely to have a relapse after treatment is discontinued.
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Amantadine
1-Aminoadamantane, 1-Adamantylamine, 1-Adamantanamine
T7060768-94-5
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.
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Mitoxantrone dihydrochloride
NSC-301739, mitozantrone dihydrochloride, Mitoxantrone hydrochloride, Mitoxantrone 2HCl
T015870476-82-3
Mitoxantrone dihydrochloride (NSC-301739) is the hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. It is a type II topoisomerase inhibitor.
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Idoxuridine
IDU, SKF 14287, 5-Iodo-2′-deoxyuridine, NSC 39661, 5-IUdR, Dendrid
T086354-42-2
Idoxuridine (Dendrid) is an analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
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Ofloxacin
DL8280, Hoe-280, Floxin, Tarivid, Oxaldin
T090282419-36-1
Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species.
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Novobiocin Sodium
Cathomycinsodium, Albamycinsodium
T09741476-53-5
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin.
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Carbenoxolone disodium
Biogastrone, Duogastrone, Bioral
T09927421-40-1
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, the drug is low in toxicity.
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Enrofloxacin
PD160788, BAY-Vp2674
T161793106-60-6
Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.
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Novobiocin
U-6391, U 6391, U6391, Cathomycin, Albamycin
T20510303-81-1
Novobiocin is an orally active and potent antibiotic.Novobiocin is a DNA gyrase inhibitor and heat shock protein 90 (Hsp90) antagonist with inhibitory effects on gyrase and Hsp90. Novobiocin has anti-positive activity and can be used to study highly resistant pneumococcal infections.
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Brincidofovir
CMX001, HDP-CDV
TQ0095444805-28-1
Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, and orthopoxviruses.
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TargetMol | Inhibitor Sale
Tiazofurin
NSC 286193, Riboxamide
T4068660084-10-8
Tiazofurin (NSC-286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent IMP dehydrogenase (IMPDH) inhibitor.
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