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By Target- Autophagy
- Mitochondrial Metabolism(1)
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Results for "
MPP iodide
" in TargetMol Product Catalog- Inhibitors & Agonists1
MPP+ iodide 
T916936913-39-0
MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons. MPP+ induces autophagic cell death in SH-SY5Y cells.
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