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Cat No. | Product Name | Synonyms | Targets |
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T5443 | JQ-1 (carboxylic acid) | JQ-1 carboxylic acid | Epigenetic Reader Domain |
JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2) | |||
T15784 | LP99 | Epigenetic Reader Domain | |
LP99 is an epigenetic probe. LP99 disrupts the binding of BRD7 and BRD9 to chromatin in cells. LP99 is an effective and selective inhibitor of the BRD7 and BRD9 bromodomains (Kd: 99 nM against BRD9). | |||
T39810 | CEM114 | ||
CEM114 is a potent chemical compound known as a chemical epigenetic modifier (CEM). It functions by employing CRISPR-Cas9 systems to harness endogenous chromatin machinery, thereby exerting its epigenetic modifying effec... | |||
T72013 | Epigenetic Multiple Ligand | ||
Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing e... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01478 | HSP90 alpha Protein, Human, Recombinant | Human | E. coli |
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe... | |||
TMPJ-00694 | BRD4 Protein, Human, Recombinant (His & Flag) | Human | E. coli |
Bromodomain-containing protein 4 (BRD4) is a member of the BET class chromatin reader proteins that bind acetylated histones and play a key role in transcriptional regulation and transmission of epigenetic memory. Remain... | |||
TMPJ-00986 | CTCF Protein, Human, Recombinant | Human | E. coli |
Transcriptional Repressor CTCF (CTCF) belongs to the CTCF Zinc-Finger Protein family. CTCF contains twelve C2H2-type zinc fingers and interacts with CHD8. CTCF is widely expressed in many tissues, and it is absent in pri... | |||
TMPH-01088 | CBX5 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphor... | |||
TMPY-02979 | HMGN3 Protein, Human, Recombinant (His) | Human | E. coli |
HMGN3 belongs to the HMGN family and is expressed in the kidney, lung, pancreas, testis, skeletal muscle, heart, thyroid gland, pituitary gland, prostate, and uterus. Members of the HMGN family bind to nucleosomes withou... | |||
TMPY-02957 | DYDC2 Protein, Human, Recombinant (GST) | Human | E. coli |
DPY30 domain containing 2 belongs to the dpy-30 family. Dumpy-30 family members act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 plays... | |||
TMPY-06845 | HSP90 alpha Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe... | |||
TMPY-06846 | HSP90 alpha Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe... |
Cat No. | Product Name | ||
---|---|---|---|
L1200 | Epigenetics Compound Library | 960 compounds | |
Well-chosen 960 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L8300 | Chromatin Modification Compound Library | 256 compounds | |
A unique collection of 256 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS); | |||
L3500 | Histone Modification Compound Library | 480 compounds | |
A unique collection of 480 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS); |