Home Tools
Log in
Cart

Search Result

Search Results for " c5a "

Targets

28

Compounds

36

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T80131 C5a Anaphylatoxin (human) Complement System
C5a Anaphylatoxin (human) is a pro-inflammatory peptide that functions as a leukocyte chemoattractant, utilized in researching inflammation and immune responses, including allergic asthma [1] [2].
T80265 C5a Receptor agonist, mouse, human Complement System
C5a Receptor Agonist (mouse, human) is a bioactive peptide derived from the C-terminus of the complement fragment 5 anaphylatoxin (C5a), functioning as an agonist for the C5a receptor. This peptide plays a role in mediat...
T9915 Eculizumab Complement System
Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5
T17250 W-54011 ROS , Complement System
W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki: 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and g...
T82797 C5aR1 antagonist peptide
C5aR1 antagonist peptide, a biologically active linear peptide originating from the C-terminus of the chemokine complement fragment 5 anaphylatoxin (C5a), inhibits C5a binding and activity at human and rat C5a receptors....
T73261 C5aR-IN-1
C5aR-IN-1 is a potent inhibitor of C5aR . Increased level of C5a has been associated with disorders such as autoimmune disorders and inflammatory disorders. C5aR-IN-1 has the potential for the research of inflammation di...
T73262 C5aR-IN-3
C5aR-IN-3 is a potent inhibitor of C5aR . Increased level of C5a has been associated with disorders such as autoimmune disorders and inflammatory disorders. C5aR-IN-3 has the potential for the research of inflammation di...
T64200 C5aR-IN-2
C5aR-IN-2 is a potent inhibitor of C5aR. C5aR-IN-2 has shown potential for the study of inflammatory diseases.
TP1834 MUC5AC motif peptide
MUC5AC motif peptide is a 16-amino acid fragment of mucin 5.
T60161 CP-289 Complement System
CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.
T12506L1 PMX 205 acetate(514814-49-4 free base) Complement System
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).
T60151 CP-447697 Complement System
CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation.
T8223 Avacopan CCX168 Complement System
Avacopan (CCX168) is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a murine model o...
TP2334 PMX 53 acetate(219639-75-5 free base) Complement System
PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an ag...
T9316 JR14a 5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride Complement System
JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor.
T12506L PMX 205 Others
PMX 205 is an effective complement antagonist of the C5a receptor.
T73710 PMX 205 Trifluoroacetate
PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.
T76913 Avdoralimab
Avdoralimab (IPH 5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1 (C5aR1) that prevents its binding to C5a. Avdoralimab can be used for complement-driven inflammatory diseases an...
T12506 PMX 205 Trifluoroacetate (514814-49-4 free base) PMX 205 Trifluoroacetate Others
PMX 205 Trifluoroacetate is a potent complement antagonist of C5a receptor.
T76958 Vilobelimab
Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti- C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhi...
T83669 PMX-53 TFA AcPhe-[Orn-Pro-D-Cyclohexylalanine-Trp-Arg],AcF-[OPdChaWR],3D53
PMX-53, a macrocyclic complement 5a (C5a) peptidomimetic and C5a receptor antagonist (IC50 = 0.3 µM), effectively inhibits the C5a-induced secretion of myeloperoxidase (MPO) in isolated human polymorphonuclear leukocytes...
T35836 PMX-205 (trifluoroacetate salt)
PMX-205 is a cyclic hexapeptide that acts as a potent antagonist of C5a receptor (C5aR; IC50= 31 nM).1It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma.2,3...
T28429 PMX-53 PMX53,PMX 53
PMX-53 is a Mas-related gene 2 (MrgX2) agonist and C5aR(CD88) antagonist. PMX-53 reduces atherosclerotic lesions in a mouse model of atherosclerosis, inhibits lung metastasis in a mouse breast cancer model, inhibits C5a-...
T74551 Avacincaptad pegol sodium
Avacincaptad pegol (ARC1905) is is an anti-C5 RNA aptamer that inhibits the cleavage of complement factor 5 (C5) into C5a and C5b. Avacincaptad pegol is being used for the study of age-related macular degeneration (AMD).
T74552 Non-PEGylated/naked ARC1905
Non-PEGylated/naked ARC1905 is is an anti-C5 RNA aptamer without PEG conjugation. Non-PEGylated/naked ARC1905 inhibits the cleavage of complement factor 5 (C5) into C5a and C5b. Non-PEGylated/naked ARC1905 is being used ...
T77107 Olendalizumab
Olendalizumab (ALXN1007) is a mouse-derived and humanized IgG2-G4-κ antibody, targeting to Complement protein C5a (K i =60 pM). Olendalizumab targets the complement inflammatory pathway. Moreover, Olendalizumab can be us...
T74650 JPE-1375
JPE-1375 is a complement C5a receptor 1 ( C5aR1 ) antagonist. JPE-1375 effectively inhibits polymorphonuclear leukocyte mobilization ( EC 50 =6.9 µM) and reduces TNF levels ( EC 50 =4.5 µM) in mice. JPE-1375 can be used ...
T79376 SARS-CoV-2 3CLpro-IN-19 SARS-CoV
SARS-CoV-2 3CLpro-IN-19 (Compound C5a), a non-covalent, non-peptide inhibitor of the SARS-CoV-2 3CLpro enzyme, exhibits potent in vitro activity with an IC50 of 0.7 μM. It demonstrates broad-spectrum efficacy against inf...

Compounds

C5a Anaphylatoxin (human)
T80131
Synonym:
Target: Complement System
C5a Receptor agonist, mouse, human
T80265
Synonym:
Target: Complement System
Eculizumab
T9915
Synonym:
Target: Complement System
W-54011
T17250
Synonym:
Target: ROS, Complement System
C5aR1 antagonist peptide
T82797
Synonym:
Target:
C5aR-IN-1
T73261
Synonym:
Target:
C5aR-IN-3
T73262
Synonym:
Target:
C5aR-IN-2
T64200
Synonym:
Target:
MUC5AC motif peptide
TP1834
Synonym:
Target:
CP-289
T60161
Synonym:
Target: Complement System
PMX 205 acetate(514814-49-4 free base)
T12506L1
Synonym:
Target: Complement System
CP-447697
T60151
Synonym:
Target: Complement System
Avacopan
T8223
Synonym: CCX168
Target: Complement System
PMX 53 acetate(219639-75-5 free base)
TP2334
Synonym:
Target: Complement System
JR14a
T9316
Synonym: 5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride
Target: Complement System
PMX 205
T12506L
Synonym:
Target: Others
PMX 205 Trifluoroacetate
T73710
Synonym:
Target:
Avdoralimab
T76913
Synonym:
Target:
PMX 205 Trifluoroacetate (514814-49-4 free base)
T12506
Synonym: PMX 205 Trifluoroacetate
Target: Others
Vilobelimab
T76958
Synonym:
Target:
PMX-53 TFA
T83669
Synonym: AcPhe-[Orn-Pro-D-Cyclohexylalanine-Trp-Arg],AcF-[OPdChaWR],3D53
Target:
PMX-205 (trifluoroacetate salt)
T35836
Synonym:
Target:
PMX-53
T28429
Synonym: PMX53,PMX 53
Target:
Avacincaptad pegol sodium
T74551
Synonym:
Target:
Non-PEGylated/naked ARC1905
T74552
Synonym:
Target:
Olendalizumab
T77107
Synonym:
Target:
JPE-1375
T74650
Synonym:
Target:
SARS-CoV-2 3CLpro-IN-19
T79376
Synonym:
Target: SARS-CoV

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00653 Complement C5 Protein, Human, Recombinant (Complement C5a) Human E. coli
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-04902 Complement C5a Protein, Mouse, Recombinant Mouse E. coli
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-05057 Complement C5 Protein, Human, Recombinant (His & FLAG) Human HEK293
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPH-03107 Complement C5a Protein, Pig, Recombinant (His) Sus scrofa (Pig) Yeast
Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT3 and more rarely with PMT2 to transfer mannose from Dol-P-mannose to Ser or Thr ...
TMPY-05459 Complement C5a Protein, Mouse, Recombinant, Biotinylated Mouse E. coli
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-06814 Complement C5 Protein, Human, Recombinant (Flag) Human HEK293
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPK-01205 MDL-1/CLEC5A Protein, Human, Recombinant (hFc) Human HEK293
In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, i...
TMPY-03760 CLEC5A Protein, Rhesus, Recombinant (His) Rhesus HEK293
CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesio...
TMPK-01218 MDL-1/CLEC5A Protein, Mouse, Recombinant (hFc) Mouse HEK293
In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, i...
TMPY-00999 UNC5A Protein, Human, Recombinant (His) Human HEK293
The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cu...
TMPY-00648 UNC5A Protein, Human, Recombinant (hFc) Human HEK293
The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cu...
TMPH-01023 C5AR1 Protein, Human, Recombinant (Cell-Free, His) Human in vitro E. coli expression system
TMPH-02121 SLC5A5 Protein, Human, Recombinant (B2M & His) Human E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l...
TMPY-03872 CLEC5A Protein, Rat, Recombinant (His) Rat HEK293
CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesio...
TMPY-03928 CLEC5A Protein, Rhesus, Recombinant (mFc) Rhesus HEK293
CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesio...
TMPH-03074 UBC5A Protein, Japonica rice, Recombinant (His & Myc) Rice E. coli
TMPH-01022 C5AR1 Protein-VLP, Human, Recombinant (His) Human HEK293
TMPH-02119 SLC5A2 Protein, Human, Recombinant (His & Myc) Human E. coli
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs). Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell. Possesses no intrinsic RNA-binding activi...
TMPH-02032 GPRC5A Protein, Human, Recombinant (GST) Human E. coli
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator...
TMPH-02120 SLC5A5 Protein, Human, Recombinant (His) Human E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l...
TMPY-06137 Complement C5 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPH-03529 Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His) Staphylococcus aureus Yeast
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leu...
TMPH-03528 Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc) Staphylococcus aureus E. coli
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leu...
TMPY-06538 Complement C5 Protein, Cynomolgus, Recombinant Cynomolgus HEK293
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPH-03184 P2 Protein, Pseudomonas phage phi6, Recombinant (His & Myc) Pseudomonas phage phi6 E. coli
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leu...
TMPH-03183 Alginate lyase Protein, Pseudomonas fluorescens, Recombinant (His & Myc) Pseudomonas fluorescens E. coli
Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leu...
TMPH-01594 CT83 Protein-VLP, Human, Recombinant (His) Human HEK293
Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane pro...
TMPH-03230 PHB depolymerase Protein, Ralstonia pickettii, Recombinant (His) Ralstonia pickettii E. coli
Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a ...
TMPH-03578 SCIN Protein, S. aureus, Recombinant (His & Myc) Staphylococcus aureus E. coli
Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a ...
TMPH-03232 HSD17B13 Protein, Rat, Recombinant (His) Rat Baculovirus
Plays an essential role in immune evasion by helping bacteria to resist complement-mediated killing by neutrophils. Inhibits the deposition of host C3b on bacterial surfaces and the release of the chemoattractant C5a by ...
TMPH-03580 Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc) Staphylococcus aureus E. coli
Plays an essential role in immune evasion by helping bacteria to resist complement-mediated killing by neutrophils. Inhibits the deposition of host C3b on bacterial surfaces and the release of the chemoattractant C5a by ...
TMPY-06679 CD55/DAF Protein, Mouse, Recombinant (hFc) Mouse HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
TMPY-00713 CD55/DAF Protein, Human, Recombinant (hFc) Human HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
TMPY-01292 CD55/DAF Protein, Human, Recombinant (His) Human HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
TMPY-02616 CD55/DAF Protein, Mouse, Recombinant (His) Mouse HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
TMPY-03004 CD55/DAF Protein, Rat, Recombinant (hFc) Rat HEK293
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It...
Complement C5 Protein, Human, Recombinant (Complement C5a)
TMPY-00653
Species: Human
Expression System: E. coli
Complement C5a Protein, Mouse, Recombinant
TMPY-04902
Species: Mouse
Expression System: E. coli
Complement C5 Protein, Human, Recombinant (His & FLAG)
TMPY-05057
Species: Human
Expression System: HEK293
Complement C5a Protein, Pig, Recombinant (His)
TMPH-03107
Species: Sus scrofa (Pig)
Expression System: Yeast
Complement C5a Protein, Mouse, Recombinant, Biotinylated
TMPY-05459
Species: Mouse
Expression System: E. coli
Complement C5 Protein, Human, Recombinant (Flag)
TMPY-06814
Species: Human
Expression System: HEK293
MDL-1/CLEC5A Protein, Human, Recombinant (hFc)
TMPK-01205
Species: Human
Expression System: HEK293
CLEC5A Protein, Rhesus, Recombinant (His)
TMPY-03760
Species: Rhesus
Expression System: HEK293
MDL-1/CLEC5A Protein, Mouse, Recombinant (hFc)
TMPK-01218
Species: Mouse
Expression System: HEK293
UNC5A Protein, Human, Recombinant (His)
TMPY-00999
Species: Human
Expression System: HEK293
UNC5A Protein, Human, Recombinant (hFc)
TMPY-00648
Species: Human
Expression System: HEK293
C5AR1 Protein, Human, Recombinant (Cell-Free, His)
TMPH-01023
Species: Human
Expression System: in vitro E. coli expression system
SLC5A5 Protein, Human, Recombinant (B2M & His)
TMPH-02121
Species: Human
Expression System: E. coli
CLEC5A Protein, Rat, Recombinant (His)
TMPY-03872
Species: Rat
Expression System: HEK293
CLEC5A Protein, Rhesus, Recombinant (mFc)
TMPY-03928
Species: Rhesus
Expression System: HEK293
UBC5A Protein, Japonica rice, Recombinant (His & Myc)
TMPH-03074
Species: Rice
Expression System: E. coli
C5AR1 Protein-VLP, Human, Recombinant (His)
TMPH-01022
Species: Human
Expression System: HEK293
SLC5A2 Protein, Human, Recombinant (His & Myc)
TMPH-02119
Species: Human
Expression System: E. coli
GPRC5A Protein, Human, Recombinant (GST)
TMPH-02032
Species: Human
Expression System: E. coli
SLC5A5 Protein, Human, Recombinant (His)
TMPH-02120
Species: Human
Expression System: E. coli
Complement C5 Protein, Cynomolgus, Recombinant (His)
TMPY-06137
Species: Cynomolgus
Expression System: HEK293
Chemotaxis inhibitory Protein, S. aureus (strain MRSA252), Recombinant (His)
TMPH-03529
Species: Staphylococcus aureus
Expression System: Yeast
Chemotaxis inhibitory Protein, S. aureus (strain NCTC 8325/PS47), Recombinant (His & Myc)
TMPH-03528
Species: Staphylococcus aureus
Expression System: E. coli
Complement C5 Protein, Cynomolgus, Recombinant
TMPY-06538
Species: Cynomolgus
Expression System: HEK293
P2 Protein, Pseudomonas phage phi6, Recombinant (His & Myc)
TMPH-03184
Species: Pseudomonas phage phi6
Expression System: E. coli
Alginate lyase Protein, Pseudomonas fluorescens, Recombinant (His & Myc)
TMPH-03183
Species: Pseudomonas fluorescens
Expression System: E. coli
CT83 Protein-VLP, Human, Recombinant (His)
TMPH-01594
Species: Human
Expression System: HEK293
PHB depolymerase Protein, Ralstonia pickettii, Recombinant (His)
TMPH-03230
Species: Ralstonia pickettii
Expression System: E. coli
SCIN Protein, S. aureus, Recombinant (His & Myc)
TMPH-03578
Species: Staphylococcus aureus
Expression System: E. coli
HSD17B13 Protein, Rat, Recombinant (His)
TMPH-03232
Species: Rat
Expression System: Baculovirus
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc)
TMPH-03580
Species: Staphylococcus aureus
Expression System: E. coli
CD55/DAF Protein, Mouse, Recombinant (hFc)
TMPY-06679
Species: Mouse
Expression System: HEK293
CD55/DAF Protein, Human, Recombinant (hFc)
TMPY-00713
Species: Human
Expression System: HEK293
CD55/DAF Protein, Human, Recombinant (His)
TMPY-01292
Species: Human
Expression System: HEK293
CD55/DAF Protein, Mouse, Recombinant (His)
TMPY-02616
Species: Mouse
Expression System: HEK293
CD55/DAF Protein, Rat, Recombinant (hFc)
TMPY-03004
Species: Rat
Expression System: HEK293
TargetMol