Bis PEG4 acid

Bis-PEG4-acid is a PEG PROTAC linker (PROteolysis TArgeting Chimera) used in targeted protein degradation applications.

Sulfone-Bis-PEG4-acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt is a PEG Linker which may be useful in the development of antibody drug conjugates.

bis-Mal-Lysine-PEG4-acid is a PEG-based PROTAC linker for synthesising PROTACs.

Bis-PEG4-sulfonic acid is a PEG-based linker for PROTACs, facilitating the conjugation of essential ligands critical for PROTAC molecule formation. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-N-bis(PEG4-C2-acid) is a polyethylene glycol (PEG) derivative used as a PEG-based PROTAC linker for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker used for synthesizing PROTACs, consisting of an amino group and two terminal carboxylic acids[1].

N-(Azido-PEG3)-N-bis(PEG4-acid) is a polyethylene glycol-based linker, designed for the synthesis of PROTACs [1].

N-(Azido-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG) derived PROTAC linker, facilitating PROTAC synthesis [1].

N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-based linker extensively used in the synthesis of PROTACs (proteolysis targeting chimeras)[1].

PEG4-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derivative functioning as a linker in PROTAC synthesis, specifically designed for creating proteolysis-targeting chimeras (PROTACs)[1].

Bis-(m-PEG4)-amidohexanoic acid is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N-Biotin-N-bis(PEG4-acid) is a polyethylene glycol (PEG) derived PROTAC linker used for the synthesis of PROTACs [1].

N-(Biotin-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-based linker molecule used in the synthesis of PROTACs[1].

N-Boc-N-bis(PEG4-acid) (Acid-apeg8-acid n-boc) is a PROTAC linker belonging to the PEG class and can be used for the synthesis of PROTAC molecules.

N-(Boc-PEG5)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-derived PROTAC linker used in PROTAC synthesis[1].

N-Me-N-bis(PEG4-acid) is a PEG-based linker used in PROTACs to join two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

NH-bis(PEG4-acid) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent featuring a tetrazine group, capable of undergoing inverse electron demand Diels-Alder (iEDDA) reactions with molecules containing TCO groups. This PEGylated derivative possesses a methyltetrazine moiety and two acidic groups. It forms stable covalent bonds with TCO-bearing compounds through a rapid and selective Diels-Alder cycloaddition, without the need for Cu catalysis or high temperatures. Additionally, its terminal carboxylic acids can react with primary amines in the presence of activators (such as EDC or HATU) to form stable amide bonds. The PEG linkage enhances the compounds water solubility. This reagent is for research use only.

Bis-sulfone-PEG4-acid is a reagent comprising sulfone and acid groups. The sulfone moiety binds to thiol groups in proteins, while the terminal acid can react with primary amines to form stable amide bonds, facilitated by activators such as [EDC or HATU].