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Search Results for " axl "

Targets

75

Compounds

3

Natural Products

30

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T73300 AXL-IN-13 FLT , TAM Receptor , PDGFR , TGF-beta/Smad
AXL-IN-13 is a potent and orally active AXL inhibitor with an IC50 value of 1.6 nM and a Kd value of 0.26 nM.AXL-IN-13 exhibits anticancer activity, reverses TGF-β1-induced epithelial-mesenchymal transition (EMT) and inh...
T63293 Axl-IN-7
Axl-IN-7 is a potent inhibitor of AXL. Axl-IN-7 can be used to study Axl-related diseases such as cancer (e.g., acute myeloid leukemia, breast cancer, melanoma, pancreatic cancer, and glial tumors), immune system disorde...
T63683 Axl-IN-11
Axl-IN-11 is a potent inhibitor of AXL. Axl-IN-11 can be used to study proliferative diseases, allergic diseases, autoimmune diseases, inflammatory diseases, cancer, transplant rejection, viral infectious diseases or oth...
T63154 Axl-IN-10
Axl-IN-10 is a potent inhibitor of AXL (IC50: 5 nM).Axl-IN-10 has good pharmacokinetic properties in animals and excellent transmembrane properties.Axl-IN-10 can be used to study proliferative, allergic, autoimmune, infl...
T79969 Axl-IN-16 TAM Receptor
Axl-IN-16, a dual Axl/HIF inhibitor, promotes Flammulina velutipes fruiting body formation and suppresses hypoxia-inducible factor activity along with receptor tyrosine kinase expression [1].
T60259 Axl-IN-4
Axl-IN-4 (Compound 24) is an inhibitor of AXL kinase with an IC 50 of 28.8 μM [1].
T63817 Axl-IN-5
Axl-IN-5 (compound 1) is an AXL inhibitor (IC50: 283 nM) that exhibits anticancer activity.
T63888 Axl-IN-12
Axl-IN-12 is a potent inhibitor of AXL. Axl-IN-12 can be used to study proliferative, allergic, autoimmune, inflammatory, cancer, transplant rejection, viral infectious diseases or other mammalian diseases.
T62962 Axl-IN-3
Axl-IN-3 is a selective, potent and orally active inhibitor of AXL kinase (IC50: 41.5 nM) and has a low inhibitory effect on other kinases.
T79045 AXL-IN-15 TAM Receptor
AXL-IN-15 (cpd391) is a potent inhibitor of Axl, exhibiting both a dissociation constant (K i) and a half-maximal inhibitory concentration (IC50) of less than 1 nanomolar (nM). It is applicable for cancer research [1].
T73310 AXL-IN-14 TAM Receptor
AXL-IN-14 is a potent, orally active inhibitor of AXL with an IC50 of 0.8 nM that effectively suppresses Gas6/AXL-mediated cell migration and invasion, reduces the expression of p-AXL and p-AKT proteins, and demonstrates...
T63320 Axl-IN-6
Axl-IN-6 is an orally active inhibitor of AXL. Axl-IN-6 demonstrated good tolerance and significant inhibition of tumor growth in the MV-4-11 subcutaneous xenograft tumor model.
T63901 Axl-IN-8
Axl-IN-8 (NO.1) is a potent inhibitor of AXL (IC50<1 nM) and also inhibits c-MET (IC50: 1-10 nM). : 120.3 nM).
T62778 Axl-IN-9
Axl-IN-9 is a potent inhibitor of AXL (IC50: 26 nM) with excellent transmembrane properties.Axl-IN-9 exhibits good pharmacokinetic properties in animals.Axl-IN-9 can be used to study proliferative, autoimmune, allergic, ...
T72574 Axl/Mer/CSF1R-IN-1
Axl/Mer-IN-1 is an Axl/Mer receptor tyrosine kinase ( Axl/Mer RTK ) and CSF1R inhibitor with K d s of <0.1 μM .
T74354 PROTAC Axl Degrader 2
PROTAC Axl Degrader 2 is a potent and selective PROTAC Axl degrader with an IC 50 of 1.61 µM. PROTAC Axl Degrader 2 shows anti-proliferation activity, anti-migration activity in vitro. PROTAC Axl Degrader 2 induces mehuo...
T74353 PROTAC Axl Degrader 1
PROTAC Axl Degrader 1 is a potent and selective PROTAC Axl degrader with an IC 50 of 0.92 µM. PROTAC Axl Degrader 1 shows anti-proliferation activity, anti-migration activity in vitro. PROTAC Axl Degrader 1 induces mehuo...
T6982 SGI-7079 FLT , c-Met/HGFR , c-RET , TAM Receptor , Src
SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is also a potential therapeutic target for EGFR inhibitor resistance.
T1968 UNC2250 TAM Receptor
UNC2250 is an effective and specific Mer inhibitor (IC50=1.7 nM).
T13074 TAM-IN-2 TAM Receptor
TAM-IN-2 is an inhibitor of TAM.
T2311 LDC1267 TAM Receptor
LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and Axl(IC50=29 nM).
T17205 UNC2541 Others , FLT , TAM Receptor
UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).
T2005 Dubermatinib TP0903 Apoptosis , TAM Receptor
Dubermatinib (TP0903) is a potent and selective Axl kinase inhibitor.
TQ0041 Ningetinib Tosylate VEGFR , c-Met/HGFR , TAM Receptor
Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.
T12731 RIPK1-IN-7 RIP kinase
RIPK1-IN-7 is a potent and selective inhibitor of RIPK1(Kd of 4 nM and an enzymatic IC50 of 11 nM),andexhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.
T6907 NPS-1034 NPS1034,NPS 1034 Apoptosis , c-Met/HGFR , TAM Receptor
NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.
T2629 UNC2881 TAM Receptor
UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.
T7425 RU-301 TAM Receptor
RU-301 is a novel pan-tam inhibitor
T21302 UNC569 UNC 569 TAM Receptor
UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amoun...
T4426 CEP-40783 CEP 40783,RXDX-106 c-Met/HGFR , TAM Receptor
CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).
T8327 ONO-7475 Trk receptor , TAM Receptor
ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase
T6269 Bemcentinib R428,BGB324 TAM Receptor
Bemcentinib (R428) is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC.
T9123 DS-1205 TAM Receptor
DS-1205 is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205 also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205 can inhibit cell migration in vitro an...
TQ0021 Ningetinib CT-053,CT053PTSA VEGFR , c-Met/HGFR , TAM Receptor
Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.
T2699 BMS 777607 BMS777607,BMS-777607,BMS 817378 c-Met/HGFR , TAM Receptor
BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3 (IC50: 3.9/1.1/1.8/4.3 nM). BMS-777607 has been investigated for the basic science of Malignant Solid Tumour.
T4409 Gilteritinib ASP2215 FLT , TAM Receptor , c-Kit
Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively). In preClinicalal studies, gilteritinib showed strong an...
T7379 2-D08 E1/E2/E3 Enzyme , TAM Receptor
2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.
T9052 XL092 CL-092,JUN04542 VEGFR , c-Met/HGFR , TAM Receptor
XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.
T2586 Cabozantinib XL184,BMS-907351 Apoptosis , VEGFR , FLT , c-Met/HGFR , c-RET , TAM Receptor , c-Kit
Cabozantinib (BMS-907351) (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50s: 0.035, 1.3, 4.6, 7 and 11.3 nM).
T4349 Sitravatinib MG516,MGCD516 Discoidin Domain Receptor (DDR) , VEGFR , FLT , Trk receptor , TAM Receptor , c-Kit , Ephrin Receptor
Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and Axl.
T5164 Cabozantinib hydrochloride XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351 VEGFR , FLT , c-Met/HGFR , TAM Receptor , c-Kit , ROR
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).
TP1713 Axltide
Axltide is based on the mouse Insulin receptor substrate 1 (amino acid 979-989).Peptide sequence (KKSRGDYMTMQIG) is based on the mouse Insulin receptor substrate 1 (amino acid 979-989).
T3274 S49076 FGFR , c-Met/HGFR , TAM Receptor
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3, blocking cellular phosphorylation of MET, AXL, and FGFRs.
T71973 Gilteritinib hemifumarate ASP2215 hemifumarate FLT , TAM Receptor
Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment of relapsed or refractory FLT3 mutant AML.
T76864 Enapotamab TAM Receptor
Enapotamab is an AXL/UFO-related antibody that can be used to synthesize antibody-drug couplings (Enapotamab Vedotin).
T16806 RU-302 [2-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]phenyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone TAM Receptor
RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks the activation of Gas6-inducible AXL and suppresses lung cancer tumor grow...
T2617 SNS-314 Mesylate SNS-314 Aurora Kinase
SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor (IC50: 9/31/3 nM). It is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.
T21302L UNC 569 hydrochloride UNC 569 hydrochloride (1350547-65-7 Free base) TAM Receptor , TAM Receptor
UNC 569 hydrochloride is a reversible and ATP-competitive inhibitor of Mer with an IC50 of 2.9 nM and a Ki of 4.3 nM. UNC 569 hydrochloride inhibits Axl and Tyro3 with IC50s of 37 nM and 48 nM, respectively. UNC 569 hydr...
T7007 UNC2025 mrx-6313,UNC-2025,UNC 2025 FLT , TAM Receptor
UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.
T60197 UNC 1025 Others
UNC1062 is a highly selective tyrosine kinase inhibitor that specifically targets MERTK. This compound effectively suppresses MERTK-mediated downstream signaling, induces apoptosis in cell cultures, reduces colony format...

Compounds

AXL-IN-13
T73300
Synonym:
Target: FLT, TAM Receptor, PDGFR, TGF-beta/Smad
Axl-IN-7
T63293
Synonym:
Target:
Axl-IN-11
T63683
Synonym:
Target:
Axl-IN-10
T63154
Synonym:
Target:
Axl-IN-16
T79969
Synonym:
Target: TAM Receptor
Axl-IN-4
T60259
Synonym:
Target:
Axl-IN-5
T63817
Synonym:
Target:
Axl-IN-12
T63888
Synonym:
Target:
Axl-IN-3
T62962
Synonym:
Target:
AXL-IN-15
T79045
Synonym:
Target: TAM Receptor
AXL-IN-14
T73310
Synonym:
Target: TAM Receptor
Axl-IN-6
T63320
Synonym:
Target:
Axl-IN-8
T63901
Synonym:
Target:
Axl-IN-9
T62778
Synonym:
Target:
Axl/Mer/CSF1R-IN-1
T72574
Synonym:
Target:
PROTAC Axl Degrader 2
T74354
Synonym:
Target:
PROTAC Axl Degrader 1
T74353
Synonym:
Target:
SGI-7079
T6982
Synonym:
Target: FLT, c-Met/HGFR, c-RET, TAM Receptor, Src
UNC2250
T1968
Synonym:
Target: TAM Receptor
TAM-IN-2
T13074
Synonym:
Target: TAM Receptor
LDC1267
T2311
Synonym:
Target: TAM Receptor
UNC2541
T17205
Synonym:
Target: Others, FLT, TAM Receptor
Dubermatinib
T2005
Synonym: TP0903
Target: Apoptosis, TAM Receptor
Ningetinib Tosylate
TQ0041
Synonym:
Target: VEGFR, c-Met/HGFR, TAM Receptor
RIPK1-IN-7
T12731
Synonym:
Target: RIP kinase
NPS-1034
T6907
Synonym: NPS1034,NPS 1034
Target: Apoptosis, c-Met/HGFR, TAM Receptor
UNC2881
T2629
Synonym:
Target: TAM Receptor
RU-301
T7425
Synonym:
Target: TAM Receptor
UNC569
T21302
Synonym: UNC 569
Target: TAM Receptor
CEP-40783
T4426
Synonym: CEP 40783,RXDX-106
Target: c-Met/HGFR, TAM Receptor
ONO-7475
T8327
Synonym:
Target: Trk receptor, TAM Receptor
Bemcentinib
T6269
Synonym: R428,BGB324
Target: TAM Receptor
DS-1205
T9123
Synonym:
Target: TAM Receptor
Ningetinib
TQ0021
Synonym: CT-053,CT053PTSA
Target: VEGFR, c-Met/HGFR, TAM Receptor
BMS 777607
T2699
Synonym: BMS777607,BMS-777607,BMS 817378
Target: c-Met/HGFR, TAM Receptor
Gilteritinib
T4409
Synonym: ASP2215
Target: FLT, TAM Receptor, c-Kit
2-D08
T7379
Synonym:
Target: E1/E2/E3 Enzyme, TAM Receptor
XL092
T9052
Synonym: CL-092,JUN04542
Target: VEGFR, c-Met/HGFR, TAM Receptor
Cabozantinib
T2586
Synonym: XL184,BMS-907351
Target: Apoptosis, VEGFR, FLT, c-Met/HGFR, c-RET, TAM Receptor, c-Kit
Sitravatinib
T4349
Synonym: MG516,MGCD516
Target: Discoidin Domain Receptor (DDR), VEGFR, FLT, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor
Cabozantinib hydrochloride
T5164
Synonym: XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351
Target: VEGFR, FLT, c-Met/HGFR, TAM Receptor, c-Kit, ROR
Axltide
TP1713
Synonym:
Target:
S49076
T3274
Synonym:
Target: FGFR, c-Met/HGFR, TAM Receptor
Gilteritinib hemifumarate
T71973
Synonym: ASP2215 hemifumarate
Target: FLT, TAM Receptor
Enapotamab
T76864
Synonym:
Target: TAM Receptor
RU-302
T16806
Synonym: [2-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]phenyl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
Target: TAM Receptor
SNS-314 Mesylate
T2617
Synonym: SNS-314
Target: Aurora Kinase
UNC 569 hydrochloride
T21302L
Synonym: UNC 569 hydrochloride (1350547-65-7 Free base)
Target: TAM Receptor, TAM Receptor
UNC2025
T7007
Synonym: mrx-6313,UNC-2025,UNC 2025
Target: FLT, TAM Receptor
UNC 1025
T60197
Synonym:
Target: Others
1 2
Cat No. Product Name Synonyms Targets
T3S0027 Picropodophyllotoxin AXL 1717,Picropodophyllin IGF-1R
Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...
T6943 Picropodophyllin AXL1717,Picropodophyllin (PPP),Picropodophyllotoxin,PPP Apoptosis , IGF-1R
Picropodophyllin (Picropodophyllin (PPP)) (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with...
TN2241 Styraxlignolide F Others
Styraxlignolide F is a natural product from Styrax japonica.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01601 AXL Protein, Human, Recombinant (His) Human HEK293
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip...
TMPK-00472 AXL Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPY-06552 AXL Protein, Rat, Recombinant (His) Rat HEK293
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip...
TMPK-00407 AXL Protein, Human, Recombinant (His & Avi) Human HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPJ-00399 AXL Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Axl, also known as Ufo and Ark, is a widely expressed 140 kDa glycoprotein in the TAM receptor tyrosine kinase family. Axl binds the vitamin K-dependent protein Gas6 which triggers tyrosine autophosphorylation of the Axl...
TMPJ-00449 AXL Protein, Human, Recombinant (hFc) Human Human Cells
Axl, also known as Ufo and Ark, is a widely expressed 140 kDa glycoprotein in the TAM receptor tyrosine kinase family. Axl binds the vitamin K-dependent protein Gas6 which triggers tyrosine autophosphorylation of the Axl...
TMPY-06478 AXL Protein, Human, Recombinant (mFc) Human HEK293
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip...
TMPY-01364 AXL Protein, Mouse, Recombinant (His) Mouse HEK293
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip...
TMPK-00408 AXL Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPY-01021 AXL Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip...
TMPK-00410 AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Human HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPJ-00365 GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signa...
TMPY-00882 Mer Protein, Human, Recombinant (His & hFc) Human HEK293
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04330 Mer Protein, Human, Recombinant Human HEK293
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04830 GAS6 Protein, Mouse, Recombinant (His) Mouse HEK293
The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPJ-00366 GAS6 Protein, Human, Recombinant (hFc) Human Human Cells
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds...
TMPY-03848 Protein S/PROS1 Protein, Human, Recombinant (His) Human HEK293
PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free,...
TMPY-06315 Protein S/PROS1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free,...
TMPJ-01017 Dtk Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Dtk, also called Tyro3, belongs to the TAM receptor family of receptor protein tyrosine kinases (RPTKs) composed of three receptors Tyro3, Axl, and Mer. These receptors share a characteristic molecular structure of two i...
TMPJ-01018 Dtk Protein, Mouse, Recombinant (mFc) Mouse Human Cells
Dtk, also called Tyro3, belongs to the TAM receptor family of receptor protein tyrosine kinases (RPTKs) composed of three receptors Tyro3, Axl, and Mer. These receptors share a characteristic molecular structure of two i...
TMPY-06708 Protein S/PROS1 Protein, Mouse, Recombinant (His) Mouse HEK293
PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free,...
TMPJ-01081 Dtk Protein, Human, Recombinant (His) Human Human Cells
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs an...
TMPK-00517 GAS6 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of ...
TMPK-00901 TYRO3 Protein, Mouse, Recombinant (His) Mouse HEK293
The TAM receptors (Tyro3, Axl and MerTK) are promising therapeutic targets on tumor-associated macrophages. The TAM receptors are a family of receptor tyrosine kinases with shared ligands Gas6 and Protein S that skew mac...
TMPK-00533 TYRO3 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The TAM receptors (Tyro3, Axl and MerTK) are promising therapeutic targets on tumor-associated macrophages. The TAM receptors are a family of receptor tyrosine kinases with shared ligands Gas6 and Protein S that skew mac...
TMPJ-01143 MERTK/Mer Protein, Human, Recombinant (aa 1-323, His) Human Human Cells
Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one...
TMPY-02291 Mer Protein, Mouse, Recombinant (hFc) Mouse HEK293
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04437 Mer Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04363 Mer Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
TMPY-04747 Mer Protein, Human, Recombinant (aa 578-872) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase MER (MERTK) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-li...
AXL Protein, Human, Recombinant (His)
TMPY-01601
Species: Human
Expression System: HEK293
AXL Protein, Cynomolgus, Recombinant (His)
TMPK-00472
Species: Cynomolgus
Expression System: HEK293
AXL Protein, Rat, Recombinant (His)
TMPY-06552
Species: Rat
Expression System: HEK293
AXL Protein, Human, Recombinant (His & Avi)
TMPK-00407
Species: Human
Expression System: HEK293
AXL Protein, Mouse, Recombinant (hFc)
TMPJ-00399
Species: Mouse
Expression System: Human Cells
AXL Protein, Human, Recombinant (hFc)
TMPJ-00449
Species: Human
Expression System: Human Cells
AXL Protein, Human, Recombinant (mFc)
TMPY-06478
Species: Human
Expression System: HEK293
AXL Protein, Mouse, Recombinant (His)
TMPY-01364
Species: Mouse
Expression System: HEK293
AXL Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00408
Species: Human
Expression System: HEK293
AXL Protein, Mouse, Recombinant (His & hFc)
TMPY-01021
Species: Mouse
Expression System: HEK293
AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
TMPK-00410
Species: Human
Expression System: HEK293
GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00365
Species: Human
Expression System: Human Cells
Mer Protein, Human, Recombinant (His & hFc)
TMPY-00882
Species: Human
Expression System: HEK293
Mer Protein, Human, Recombinant
TMPY-04330
Species: Human
Expression System: HEK293
GAS6 Protein, Mouse, Recombinant (His)
TMPY-04830
Species: Mouse
Expression System: HEK293
GAS6 Protein, Human, Recombinant (hFc)
TMPJ-00366
Species: Human
Expression System: Human Cells
Protein S/PROS1 Protein, Human, Recombinant (His)
TMPY-03848
Species: Human
Expression System: HEK293
Protein S/PROS1 Protein, Cynomolgus, Recombinant (His)
TMPY-06315
Species: Cynomolgus
Expression System: HEK293
Dtk Protein, Mouse, Recombinant (hFc)
TMPJ-01017
Species: Mouse
Expression System: Human Cells
Dtk Protein, Mouse, Recombinant (mFc)
TMPJ-01018
Species: Mouse
Expression System: Human Cells
Protein S/PROS1 Protein, Mouse, Recombinant (His)
TMPY-06708
Species: Mouse
Expression System: HEK293
Dtk Protein, Human, Recombinant (His)
TMPJ-01081
Species: Human
Expression System: Human Cells
GAS6 Protein, Cynomolgus, Recombinant (His)
TMPK-00517
Species: Cynomolgus
Expression System: HEK293
TYRO3 Protein, Mouse, Recombinant (His)
TMPK-00901
Species: Mouse
Expression System: HEK293
TYRO3 Protein, Cynomolgus, Recombinant (His)
TMPK-00533
Species: Cynomolgus
Expression System: HEK293
MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)
TMPJ-01143
Species: Human
Expression System: Human Cells
Mer Protein, Mouse, Recombinant (hFc)
TMPY-02291
Species: Mouse
Expression System: HEK293
Mer Protein, Mouse, Recombinant (His & GST)
TMPY-04437
Species: Mouse
Expression System: Baculovirus-Insect Cells
Mer Protein, Human, Recombinant (His & GST)
TMPY-04363
Species: Human
Expression System: Baculovirus-Insect Cells
Mer Protein, Human, Recombinant (aa 578-872)
TMPY-04747
Species: Human
Expression System: Baculovirus-Insect Cells
TargetMol