β-carboline

Tetrahydro-β-carboline ,with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Tetrahydro-β-carboline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-Spiro(piperidin-4-yl)-2,3,4,9-tetrahydro-1H-β-carboline ,with CAS No. 119990-83-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-Spiro(piperidin-4-yl)-2,3,4,9-tetrahydro-1H-β-carboline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

9-Methyl-β-carboline is a cognitive enhancer with neuroprotective, neurorestorative, and anti-inflammatory properties. Its behavioral effects may be linked to hippocampal dopamine levels and the stimulation of dendritic and synaptic proliferation.

3-(3-Phenoxybenzyl)amino-β-carboline is a highly effective tubulin inhibitor, selectively degrading αβ-tubulin heterodimers, inducing cell cycle arrest and apoptosis in the G2/M phase, and displaying notable anticancer activity [1].

β-Carboline-1-carboxylic acid is an alkaloid that has been found in P. quassioides and has diverse biological activities. It reduces LPS-induced increases in MCP-1, TNF-α, IL-6, and IL-1β levels in RAW 264.7 cells when used at a concentration of 15 µg/ml and inhibits the epithelial-to-mesenchymal transition (EMT) induced by TGF-β1 in A549 cells. β-Carboline-1-carboxylic acid induces cytotoxicity in CT26.WT, K562, and SGC-7901 cells (IC50s = 14.96, 22.11, and 19.7 µg/ml, respectively) but not HepG2 or A549 cells (IC50s = 36.41 and 41.51 µg/ml, respectively). It also inhibits cAMP phosphodiesterase with an IC50 value of 96 µM.

7-Methoxy-β-carboline-1-propionic acid (compound 46), recognized for its cytotoxic and antimalarial properties, is derived from the roots of Eurycoma longifolia [1].

1-Methoxymethyl-β-carboline, a natural product, has been isolated from the root of Eurycoma longifolia [1].

Ethyl β-carboline-3-carboxylate (fl-CCE), a benzodiazepine receptor ligand and short-acting antagonist, does not impact cerebellar cGMP levels on its own. However, it considerably suppresses the increase in cGMP levels caused by Diazepam when both are administered together.

7-Fluoro-2,3,4,9-tetrahydro-1H-beta-carboline, with CAS No. 177858-80-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Fluoro-2,3,4,9-tetrahydro-1H-beta-carboline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-vinyl-4-dimethoxy-beta-carboline is a natural product from Picrasma javanica.

1-Methoxycarbonyl-β-carboline (1-Methoxycarbonyl-beta-carboline) is an alkaloid from Ailanthus altissima.

1,2,3,4-Tetrahydro-β-carboline-1-carboxylic acid is a neuroactive compound used in neurodegenerative disease research.

β-Carboline-1-propionic acid is an alkaloid discovered in Ailanthus altissima that exhibits anti-Leishmania activity.

1-Acetyl-β-carboline is a bioactive metabolite derived from Streptomyces kasugaensis that exhibits antibacterial properties, enhances tyrosinase activity, reduces ERK phosphorylation, and increases melanin production, while demonstrating antibacterial efficacy against methicillin-resistant Staphylococcus aureus strains with minimum inhibitory concentrations ranging from 128 to 256 μg/mL, supporting the use of 1-Acetyl-β-carboline in the investigation in antimicrobial and pigmentation-related biochemical research.

4-Methoxy-1-methoxycarbonyl-β-carboline is a natural product for research related to life sciences. The catalog number is TN6008 and the CAS number is 60807-25-2.

1-(3,4,5-Trihydroxypentanoyl)-β-carboline is a natural product for research related to life sciences. The catalog number is TN6093 and the CAS number is 180995-40-8.

1-Ethoxycarbonyl-β-carboline is a natural product for research related to life sciences. The catalog number is TN7072 and the CAS number is 72755-19-2.

Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family.

AalphaC (2-Amino-alpha-carboline) is a potential carcinogen.

Harmane (Loturine) is a bio-active β-Carboline and monoamine oxidase inhibitor found in coffee and tobacco smoke.

1-Hydroxymethyl-beta-carboline glucoside is a natural product from Picrasmae Ramulus et Folium.

Crenatine possesses antibacterial activity, it is more effective against Gram-positive than Gram-negative bacteria.

1-Methoxycarbonyl-beta-carboline-N-oxide is a natural product for research related to life sciences. The catalog number is TN6652 and the CAS number is 74690-74-7.

Ethyl beta-carboline-1-propionate is a useful organic compound for research related to life sciences and the catalog number is T123952.