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RAAS

The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure and fluid and electrolyte balance, as well as systemic vascular resistance.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T6698 Temocapril hydrochloride 110221-44-8 99.26%
Temocapril hydrochloride
Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.
T13865 Resorcinolnaphthalein 41307-63-5 99.25%
Resorcinolnaphthalein
Resorcinolnaphthalein is a specific enhancer of angiotensin-converting enzyme 2 (ACE2) (EC50 value of 19.5 μM).
T25832 Moveltipril 85856-54-8 99.25%
Moveltipril
Moveltipril (Moveltipril calcium) is a potent angiotensin-converting enzyme (ACE) inhibitor.Moveltipril is converted to captopril in the body for action.
T6716 Valsartan 137862-53-4 99.24%
Valsartan
Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.
T3281 Delapril hydrochloride 83435-67-0 99.24%
Delapril hydrochloride
Delapril hydrochloride (indalapril) is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites b...
T13390 ZD 7155 hydrochloride 146709-78-6 99.23%
ZD 7155 hydrochloride
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
T22574L Angiotensin 1/2 (5-7) acetate T22574L 99.13%
Angiotensin 1/2 (5-7) acetate
Angiotensin 1/2 (5-7) acetate is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is d...
T16116 MLN-4760 305335-31-3 99.05%
MLN-4760
MLN-4760 is an angiotensin-converting (ACE2) inhibitor(human ACE2;IC50=0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including ...
T67848 Valsartan Methyl Ester 137863-17-3 98.94%
Valsartan Methyl Ester
Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.
T7797 Tasosartan 145733-36-4 98.93%
Tasosartan
Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).
T1518 Olmesartan Medoxomil 144689-63-4 98.92%
Olmesartan Medoxomil
Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.
T8560 Angiotensin II human acetate 68521-88-0 98.89%
Angiotensin II human acetate
Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.
T65739 Methyl candesartan 139481-69-9 98.82%
Methyl candesartan
Methyl candesartan (Candesartan Methyl Ester) is a potent angiotensin 2 receptor antagonist used in the study of hypertension.
T5355 Sparsentan 254740-64-2 98.81%
Sparsentan
Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM, respective...
T1570 Telmisartan 144701-48-4 98.78%
Telmisartan
Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.
T0805 Quinapril hydrochloride 82586-55-8 98.76%
Quinapril hydrochloride
Quinapril hydrochloride (PD-109452-2) is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quina...
T14337 Buloxibutid 477775-14-7 98.58%
Buloxibutid
Buloxibutid (AT2 receptor agonist C21) is a novel and selective small molecule angiotensin II AT2 receptor agonist with Ki values of 0.4 nM and 10 μM for AT2 and...
T3064 VTP-27999 942142-51-0 98.53%
VTP-27999
VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function.
T1645 Ramipril 87333-19-5 98.51%
Ramipril
Ramipril (Altace) is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat....
T28437L Pomisartan 2HCl 98.48%
Pomisartan 2HCl
Pomisartan 2HCl (BIBR363 2HCL) is a small molecule AT1R antagonist used to study heart failure and hypertension.
Temocapril hydrochloride
T6698
Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.
Resorcinolnaphthalein
T13865
Resorcinolnaphthalein is a specific enhancer of angiotensin-converting enzyme 2 (ACE2) (EC50 value of 19.5 μM).
Moveltipril
T25832
Moveltipril (Moveltipril calcium) is a potent angiotensin-converting enzyme (ACE) inhibitor.Moveltipril is converted to captopril in the body for action.
Valsartan
T6716
Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.
Delapril hydrochloride
T3281
Delapril hydrochloride (indalapril) is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites b...
ZD 7155 hydrochloride
T13390
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
Angiotensin 1/2 (5-7) acetate
T22574L
Angiotensin 1/2 (5-7) acetate is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is d...
MLN-4760
T16116
MLN-4760 is an angiotensin-converting (ACE2) inhibitor(human ACE2;IC50=0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including ...
Valsartan Methyl Ester
T67848
Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.
Tasosartan
T7797
Tasosartan (WAY-ANA 756) is an antagonist of angiotensin II type 2 (AT2) receptor (IC50 = 1.2 nM).
Olmesartan Medoxomil
T1518
Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.
Angiotensin II human acetate
T8560
Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.
Methyl candesartan
T65739
Methyl candesartan (Candesartan Methyl Ester) is a potent angiotensin 2 receptor antagonist used in the study of hypertension.
Sparsentan
T5355
Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM, respective...
Telmisartan
T1570
Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.
Quinapril hydrochloride
T0805
Quinapril hydrochloride (PD-109452-2) is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quina...
Buloxibutid
T14337
Buloxibutid (AT2 receptor agonist C21) is a novel and selective small molecule angiotensin II AT2 receptor agonist with Ki values of 0.4 nM and 10 μM for AT2 and...
VTP-27999
T3064
VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function.
Ramipril
T1645
Ramipril (Altace) is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat....
Pomisartan 2HCl
T28437L
Pomisartan 2HCl (BIBR363 2HCL) is a small molecule AT1R antagonist used to study heart failure and hypertension.
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TargetMol