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RAAS

The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure and fluid and electrolyte balance, as well as systemic vascular resistance.
Cat. No. Product name CAS No. Purity Chemical Structure
T3461 Losartan Carboxylic Acid 124750-92-1 98%
EXP-3174 is a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. EXP3174, a metabolite of losartan, is...
TP2158L1 TRV-120027 acetate (1234510-46-3 free base) 1824712-70-0 98%
TRV-120027 acetate is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1 receptor) and engages -arrestins while blocking G-protein signali...
T6698 Temocapril hydrochloride 110221-44-8 98%
Temocapril HCl, the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.
T7575L1 [Sar1, Ile8]-Angiotensin II acetate 98%
[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1,...
T3851 Vicenin 2 23666-13-9 98%
Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-gl...
T5796 Plantainoside D 147331-98-4 98%
Plantainoside D shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vitr...
T8560 Angiotensin II human acetate 68521-88-0 98%
Angiotensin II acetate is a vasoconstrictor that mainly acts on the AT1 receptor.
T9109 SSAA09E2 883944-52-3 98%
SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2...
T13376 YS-49 132836-42-1 98%
YS-49 is an activator of PI3K/Akt (a downstream target of RhoA).
TP1920L1 Acein acetate TP1920L1 98%
High affinity angiotensin-converting enzyme (ACE) ligand (Kd = 2.79 nM). Exhibits no significant effect on ACE enzymatic activity up to 500 nM concentration. Pot...
TP1579 Angiotensin I/II (1-6) 47896-63-9 98%
Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide.
TP1622 DX600 TFA TP1622 98%
DX600 TFA is a specific inhibitor of ACE2 and does not cross-react with ACE.
T1461 Candesartan 139481-59-7 98%
Candesartan is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
T2690 Tranilast 53902-12-8 98%
Tranilast, an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of allergic disorder...
T37496L Alamandine TFA T37496L 98%
Alamandine TFA , a member of the renin-angiotensin system (RAS), a vasoactive peptide, is an endogenous ligand of the G protein-coupled receptor MrgD. Alamandine...
T5030 Zofenopril calcium 81938-43-4 98%
Zofenopril Calcium(SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metabolic...
T6716 Valsartan 137862-53-4 98%
Valsartan is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.
T2270 Trans-Tranilast 70806-55-2 98%
Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indications...
T19930 Nitrosoglutathione 57564-91-7 98%
GSNO is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins.
TP1017L Angiotensin II 5-valine TFA TP1017L 98%
Angiotensin II 5-valine TFA is an agonist of angiotensin receptor.
Losartan Carboxylic Acid
T3461
EXP-3174 is a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. EXP3174, a metabolite of losartan, is...
TRV-120027 acetate (1234510-46-3 free base)
TP2158L1
TRV-120027 acetate is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1 receptor) and engages -arrestins while blocking G-protein signali...
Temocapril hydrochloride
T6698
Temocapril HCl, the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.
[Sar1, Ile8]-Angiotensin II acetate
T7575L1
[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1,...
Vicenin 2
T3851
Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-gl...
Plantainoside D
T5796
Plantainoside D shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vitr...
Angiotensin II human acetate
T8560
Angiotensin II acetate is a vasoconstrictor that mainly acts on the AT1 receptor.
SSAA09E2
T9109
SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2...
YS-49
T13376
YS-49 is an activator of PI3K/Akt (a downstream target of RhoA).
Acein acetate
TP1920L1
High affinity angiotensin-converting enzyme (ACE) ligand (Kd = 2.79 nM). Exhibits no significant effect on ACE enzymatic activity up to 500 nM concentration. Pot...
Angiotensin I/II (1-6)
TP1579
Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide.
DX600 TFA
TP1622
DX600 TFA is a specific inhibitor of ACE2 and does not cross-react with ACE.
Candesartan
T1461
Candesartan is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
Tranilast
T2690
Tranilast, an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of allergic disorder...
Alamandine TFA
T37496L
Alamandine TFA , a member of the renin-angiotensin system (RAS), a vasoactive peptide, is an endogenous ligand of the G protein-coupled receptor MrgD. Alamandine...
Zofenopril calcium
T5030
Zofenopril Calcium(SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metabolic...
Valsartan
T6716
Valsartan is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.
Trans-Tranilast
T2270
Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indications...
Nitrosoglutathione
T19930
GSNO is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins.
Angiotensin II 5-valine TFA
TP1017L
Angiotensin II 5-valine TFA is an agonist of angiotensin receptor.
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