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Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.
Cat. No. Product name CAS No. Purity Chemical Structure
T1270 Vincristine sulfate 2068-78-2 99.87%
Vincristine binds irreversibly to microtubules (Ki: 85 nM) and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spi...
T1155 Mebendazole 31431-39-7 99.88%
Mebendazole is a hedgehog inhibitor, used as an antihelminthic.
T2543 Cabazitaxel 183133-96-2 99.88%
Cabazitaxel is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docet...
T4677 MMAD 203849-91-6 99.91%
MMAD is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).
T5007 Benproperine phosphate 19428-14-9 99.92%
Benproperine phosphate is a cough suppressant.
T0651 N-Phenylbenzylamine 103-32-2 99.93%
A series of benzylaniline hydrochlorides as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization
T0938 Thiabendazole 148-79-8 99.94%
Thiabendazole is a benzimidazole derivative with anthelminthic property.
T2220 2-Methoxyestradiol 362-07-2 99.95%
2-Methoxyestradiol is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing en...
T6272 Fosbretabulin Disodium 168555-66-6 99.96%
Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium, a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tu...
T0320 Colchicine 64-86-8 99.96%
Colchicine is a tubulin inhibitor (IC50: 3 nM) and blocks polymerization of microtubules by binding to tubulin.
T2773 Vindoline 2182-14-1 99.97%
Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.
T7003 Leucomethylene blue mesylate 1236208-20-0 99.99%
TRx 0237 (LMTX) mesylate is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia.
T4968 KHS 101 1262770-73-9 98%
KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
T22118 NQTrp 185351-19-3 98%
NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.
T9595 LP-261 915412-67-8 98%
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.
T15236 Entasobulin 501921-61-5 98%
Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.
T9504 MAP4343 511-26-2 98%
Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, ...
T14350 Soblidotin 149606-27-9 97.48%
Soblidotin (Auristatin PE) is an inhibitor of tubulin polymerization. It also is a novel synthetic Dolastatin 10 derivative.
T6864 Ixabepilone 219989-84-1 98%
Ixabepilone is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arres...
T19720 Colcemid 477-30-5 99.66%
Demecolcine is an inhibitor of microtubule polymerization. It used to study embryonic cloning.
Vincristine sulfate
T1270
Vincristine binds irreversibly to microtubules (Ki: 85 nM) and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spi...
Mebendazole
T1155
Mebendazole is a hedgehog inhibitor, used as an antihelminthic.
Cabazitaxel
T2543
Cabazitaxel is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docet...
MMAD
T4677
MMAD is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).
Benproperine phosphate
T5007
Benproperine phosphate is a cough suppressant.
N-Phenylbenzylamine
T0651
A series of benzylaniline hydrochlorides as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization
Thiabendazole
T0938
Thiabendazole is a benzimidazole derivative with anthelminthic property.
2-Methoxyestradiol
T2220
2-Methoxyestradiol is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing en...
Fosbretabulin Disodium
T6272
Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium, a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tu...
Colchicine
T0320
Colchicine is a tubulin inhibitor (IC50: 3 nM) and blocks polymerization of microtubules by binding to tubulin.
Vindoline
T2773
Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.
Leucomethylene blue mesylate
T7003
TRx 0237 (LMTX) mesylate is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia.
KHS 101
T4968
KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
NQTrp
T22118
NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.
LP-261
T9595
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.
Entasobulin
T15236
Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.
MAP4343
T9504
Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, ...
Soblidotin
T14350
Soblidotin (Auristatin PE) is an inhibitor of tubulin polymerization. It also is a novel synthetic Dolastatin 10 derivative.
Ixabepilone
T6864
Ixabepilone is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arres...
Colcemid
T19720
Demecolcine is an inhibitor of microtubule polymerization. It used to study embryonic cloning.
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