T1270 |
Vincristine sulfate
|
2068-78-2
|
99.87%
|
|
Vincristine binds irreversibly to microtubules (Ki: 85 nM) and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spi...
|
T1155 |
Mebendazole
|
31431-39-7
|
99.88%
|
|
Mebendazole is a hedgehog inhibitor, used as an antihelminthic.
|
T2543 |
Cabazitaxel
|
183133-96-2
|
99.88%
|
|
Cabazitaxel is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docet...
|
T4677 |
MMAD
|
203849-91-6
|
99.91%
|
|
MMAD is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).
|
T5007 |
Benproperine phosphate
|
19428-14-9
|
99.92%
|
|
Benproperine phosphate is a cough suppressant.
|
T0651 |
N-Phenylbenzylamine
|
103-32-2
|
99.93%
|
|
A series of benzylaniline hydrochlorides as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization
|
T0938 |
Thiabendazole
|
148-79-8
|
99.94%
|
|
Thiabendazole is a benzimidazole derivative with anthelminthic property.
|
T2220 |
2-Methoxyestradiol
|
362-07-2
|
99.95%
|
|
2-Methoxyestradiol is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing en...
|
T6272 |
Fosbretabulin Disodium
|
168555-66-6
|
99.96%
|
|
Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium, a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tu...
|
T0320 |
Colchicine
|
64-86-8
|
99.96%
|
|
Colchicine is a tubulin inhibitor (IC50: 3 nM) and blocks polymerization of microtubules by binding to tubulin.
|
T2773 |
Vindoline
|
2182-14-1
|
99.97%
|
|
Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.
|
T7003 |
Leucomethylene blue mesylate
|
1236208-20-0
|
99.99%
|
|
TRx 0237 (LMTX) mesylate is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia.
|
T4968 |
KHS 101
|
1262770-73-9
|
98%
|
|
KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
|
T22118 |
NQTrp
|
185351-19-3
|
98%
|
|
NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.
|
T9595 |
LP-261
|
915412-67-8
|
98%
|
|
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.
|
T15236 |
Entasobulin
|
501921-61-5
|
98%
|
|
Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.
|
T9504 |
MAP4343
|
511-26-2
|
98%
|
|
Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, ...
|
T14350 |
Soblidotin
|
149606-27-9
|
97.48%
|
|
Soblidotin (Auristatin PE) is an inhibitor of tubulin polymerization. It also is a novel synthetic Dolastatin 10 derivative.
|
T6864 |
Ixabepilone
|
219989-84-1
|
98%
|
|
Ixabepilone is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arres...
|
T19720 |
Colcemid
|
477-30-5
|
99.66%
|
|
Demecolcine is an inhibitor of microtubule polymerization. It used to study embryonic cloning.
|