Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.

Cat. No.	Product name	CAS No.	Purity
T1270	Vincristine sulfate	2068-78-2	99.87%
T1270	Vincristine binds irreversibly to microtubules (Ki: 85 nM) and spindle proteins in S phase of the cell cycle and interferes with the formation of the mitotic spi...
T1155	Mebendazole	31431-39-7	99.88%
T1155	Mebendazole is a hedgehog inhibitor, used as an antihelminthic.
T2543	Cabazitaxel	183133-96-2	99.88%
T2543	Cabazitaxel is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docet...
T4677	MMAD	203849-91-6	99.91%
T4677	MMAD is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).
T5007	Benproperine phosphate	19428-14-9	99.92%
T5007	Benproperine phosphate is a cough suppressant.
T0651	N-Phenylbenzylamine	103-32-2	99.93%
T0651	A series of benzylaniline hydrochlorides as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization
T0938	Thiabendazole	148-79-8	99.94%
T0938	Thiabendazole is a benzimidazole derivative with anthelminthic property.
T2220	2-Methoxyestradiol	362-07-2	99.95%
T2220	2-Methoxyestradiol is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing en...
T6272	Fosbretabulin Disodium	168555-66-6	99.96%
T6272	Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium, a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tu...
T0320	Colchicine	64-86-8	99.96%
T0320	Colchicine is a tubulin inhibitor (IC50: 3 nM) and blocks polymerization of microtubules by binding to tubulin.
T2773	Vindoline	2182-14-1	99.97%
T2773	Vindoline is an indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly.
T7003	Leucomethylene blue mesylate	1236208-20-0	99.99%
T7003	TRx 0237 (LMTX) mesylate is a second-generation tau protein aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia.
T4968	KHS 101	1262770-73-9	98%
T4968	KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
T22118	NQTrp	185351-19-3	98%
T22118	NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.
T9595	LP-261	915412-67-8	98%
T9595	LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.
T15236	Entasobulin	501921-61-5	98%
T15236	Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.
T9504	MAP4343	511-26-2	98%
T9504	Map4343 is a 3-methyl ether derivative of pregnenolone. Map4343 binds to microtubule associated protein 2 (MAP2) in vitro and stimulates tubulin polymerization, ...
T14350	Soblidotin	149606-27-9	97.48%
T14350	Soblidotin (Auristatin PE) is an inhibitor of tubulin polymerization. It also is a novel synthetic Dolastatin 10 derivative.
T6864	Ixabepilone	219989-84-1	98%
T6864	Ixabepilone is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arres...
T19720	Colcemid	477-30-5	99.66%
T19720	Demecolcine is an inhibitor of microtubule polymerization. It used to study embryonic cloning.