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Microtubule Associated

Microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs bind to the tubulin subunits that make up microtubules to regulate their stability. A large variety of MAPs have been identified in many different cell types, and they have been found to carry out a wide range of functions. These include both stabilizing and destabilizing microtubules, guiding microtubules towards specific cellular locations, cross-linking microtubules and mediating the interactions of microtubules with other proteins in the cell.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T67935 Tubulin inhibitor 11 2366260-33-3 98.32%
Tubulin inhibitor 11
Tubulin Inhibitor 11 is a potent, orally active agent that inhibits tubulin by targeting the Colchicine binding site. It impedes tubulin polymerization, leading ...
T6490 Epothilone A 152044-53-6 98.27%
Epothilone A
Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.
T15012 Crolibulin 1000852-17-4 98.19%
Crolibulin
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.
T77519 FC-116 2417298-29-2 98.18%
FC-116
FC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice. FC-116 induces apoptosis in colorectal cancer (CRC) cells and p...
TN2254 Taccalonolide A 108885-68-3 98.16%
Taccalonolide A
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is ...
T15141 DM4 796073-69-3 98.15%
DM4
DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
T2543 Cabazitaxel 183133-96-2 98.14%
Cabazitaxel
Cabazitaxel (taxoid XRP6258) is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after...
T67964 Terflavoxate 86433-40-1 98.07%
Terflavoxate
Terflavoxate is a novel, orally active, semisynthetic statin microtubule inhibitor commonly used in combination with capecitabine. Terflavoxate is used in cancer...
T16788 Rosabulin 501948-05-6 98.06%
Rosabulin
v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency. Rosabulin inhibits microtubule assembly and has broad-spectrum antitumor activity....
T6372 Albendazole sulfoxide 54029-12-8 98.04%
Albendazole sulfoxide
Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.
T15612 JH-VIII-157-02 1639422-97-1 98.02%
JH-VIII-157-02
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-A...
T4968 KHS 101 1262770-73-9 98.00%
KHS 101
KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
T6071 Parbendazole 14255-87-9 98%
Parbendazole
Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control ...
T5860 CK-869 388592-44-7 98%
CK-869
CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.
T5699 SSE15206 1370046-40-4 98%
SSE15206
SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance. Causes aberrant mitosis resulting in G2/M arrest due to incomplete spindl...
T13298 Verubulin hydrochloride 917369-31-4 97.93%
Verubulin hydrochloride
Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic ac...
T0006 Methylene Blue trihydrate 7220-79-3 97.61%
Methylene Blue trihydrate
Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water o...
T3330L Cis-trismethoxy Resveratrol 94608-23-8 97.55%
cis-trismethoxy Resveratrol
cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.
T14350 Soblidotin 149606-27-9 97.48%
Soblidotin
Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.
T8342 BRD9876 32703-82-5 97.22%
BRD9876
BRD9876 is a selective inhibitor of MM1S growth.
Tubulin inhibitor 11
T67935
Tubulin Inhibitor 11 is a potent, orally active agent that inhibits tubulin by targeting the Colchicine binding site. It impedes tubulin polymerization, leading ...
Epothilone A
T6490
Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.
Crolibulin
T15012
Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.
FC-116
T77519
FC-116 is a potent Tubulin inhibitor with antitumour activity and inhibits tumour growth in mice. FC-116 induces apoptosis in colorectal cancer (CRC) cells and p...
Taccalonolide A
TN2254
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is ...
DM4
T15141
DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
Cabazitaxel
T2543
Cabazitaxel (taxoid XRP6258) is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after...
Terflavoxate
T67964
Terflavoxate is a novel, orally active, semisynthetic statin microtubule inhibitor commonly used in combination with capecitabine. Terflavoxate is used in cancer...
Rosabulin
T16788
v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency. Rosabulin inhibits microtubule assembly and has broad-spectrum antitumor activity....
Albendazole sulfoxide
T6372
Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.
JH-VIII-157-02
T15612
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-A...
KHS 101
T4968
KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
Parbendazole
T6071
Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control ...
CK-869
T5860
CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.
SSE15206
T5699
SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance. Causes aberrant mitosis resulting in G2/M arrest due to incomplete spindl...
Verubulin hydrochloride
T13298
Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic ac...
Methylene Blue trihydrate
T0006
Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water o...
cis-trismethoxy Resveratrol
T3330L
cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.
Soblidotin
T14350
Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.
BRD9876
T8342
BRD9876 is a selective inhibitor of MM1S growth.
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TargetMol