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Microbiology/Virology Influenza Virus

Influenza Virus

Influenza, commonly known as "the flu", is an infectious disease caused by an influenza virus. Symptoms can be mild to severe. The most common symptoms include: high fever, runny nose, sore throat, muscle and joint pain, headache, coughing, and feeling tired . Three of the four types of influenza viruses affect humans: Type A, Type B, and Type C. Type D has not been known to infect humans, but is believed to have the potential to do so.
Cat No. product name
T9124 Laninamivir octanoate Laninamivir octanoate is a long acting influenza neuraminidase (NA) inhibitor which shows superior anti-influenza virus activity.
T7602 Theaflavin Theaflavin is a polyphenolic flavonoid that has been found in black tea and has diverse biological activities, including antioxidant, anticancer, anti-inflammato...
TN1693 Glabrone Glabrone shows antiviral activity against influenza virus.
TN1506 Clemastanin B Clemastanin B has antioxidant and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and bl...
TN1480 Cephaeline Cephaeline was highly active against protected primary CLL cells (relative IC50's 35nM ) and acted by repressing HIF-1α± and disturbing intracellular redox hom...
TN1103 Diphyllin Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.
TN1073 Nuezhenidic acid Nuezhenidic acid is a natural product, posseses inhibitory activities against influenza A virus.
TN1066 Filixic acid ABA Filixic acid ABA exhibits inhibitory effects on neuraminidase of influenza virus H5N1 with IC50 as 29.57 ± 2.48 μM, it may have anti-influenza virus activity.
T8263 3,4'-Dihydroxyflavone 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus[1].
T7785 T-1105 T-1105 is a broad-spectrum antiviral inhibitor.
T7330 Nucleozin Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.
TN2231 Soyasaponin II Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1.
T6195 Baloxavir marboxil Baloxavir marboxil is a novel cap-dependent endonuclease inhibitor for the treatment of influenza A and B virus infections.
T5186 Oseltamivir acid Oseltamivir acid (GS4071) is a potent influenza virus neuraminidase inhibitor and the prodrug of GS4071.
T4377 Pimodivir Pimodivir, an influenza A virus polymerases inhibitor via oral, interacts with the viral PB2 subunit.
T4027 KIN1148 KIN1148 is a novel small-molecule adjuvant that acts through the RIG-I pathway and IRF-3 transcription factor to stimulate inN/Ate immunity and protection follow...
T1486 Oseltamivir phosphate Oseltamivir Phosphate is the phosphate salt of oseltamivir, a synthetic derivative prodrug of ethyl ester with antiviral activity. By blocking neuraminidases on ...
T3794 1,2,3,4,6-O-Pentagalloylglucose 1, 2, 3, 4, 6-Pentagalloylglucose and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-...
T2529 Zanamivir Zanamivir is a guanido-neuraminic acid that is used to inhibit NEURAMINIDASE.
T6642 Rimantadine Rimantadine (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.
T0104 Arbidol hydrochloride Arbidol (Umifenovir) hydrochloride, an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with host c...
TN2176 Sanggenol A Sanggenol A shows neuroprotective activity on glutamate-induced cell death in HT22 cells, with EC50 values of 34.03 ± 7.71 μM. Sanggenol A inhibits influenza A...
TN2331 Eleutheroside B1 Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine gene...
TP1782L CEF3 acetate(199727-62-3 free base) CEF3 acetate corresponds to aa 13-21 of the influenza A virus M1 protein. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays es...
T15707 Laninamivir Laninamivir is an effective inhibitor of influenza neuraminidase (NA) (IC50s: 0.90 nM, 1.83 nM, and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI...
TP1822L CEF6 acetate(913545-15-0 free base) CEF6 acetate is a HLA-B7 restricted influenza virus nucleoprotein epitope, belongs to the CEF control peptides. The CEF control peptides are 8-12 amino acids in ...
T8793 CBS1117 CBS1117 is a virus entry inhibitor (IC50 of 70 nM for influenza A virus, A/Puerto Rico/8/34 (H1N1)). It interferes with the hemagglutinin (HA)-mediated fusion ...
TN5005 Shegansu B Shegansu B exhibits significant in vitro anti-influenza viral activity in MDCK cells.
TN4810 Platyphyllonol Platyphyllonol-5-xylopyranoside is moderately active against KBNP-0028 (H9N2) avian influenza virus as compared with zanamivir.
TN4716 Oplodiol Oplodiol exhibits noteworthy anti-plasmodial activity against Plasmodium falciparum strains. Oplodiol has a stimulative effect on significantly proliferation and...
TN4392 Koaburaside Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have...
TN3461 Asebotin Asebotin shows anti-influenza A virus activity, it also possesses potent antiviral activity (100% inhibition at the concentration of 1 ug /mL) against highly pat...
T4S1114 Dryocrassin ABBA Dryocrassin ABBA is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities.
T15770 LNK754 LNK754 is a farnesyltransferase inhibitor. It is used for the treatment of cancer and Alzheimer's disease.
T15707 Laninamivir Laninamivir is an effective inhibitor of influenza neuraminidase (NA) (IC50s: 0.90 nM, 1.83 nM, and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI...
T8354 Triazavirin Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.
T13229 Tunicamycin Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin inhibit...
T12953 Sodium copper chlorophyllin B Sodium copper chlorophyllin B exerts antiviral activities against Influenza virus and HIV (IC50s of 50 to 100 μM).
T12818 S119-8 RN-18 antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G. RN-18 increases cellular A3G levels in a Vif-dependent manner and incr...
T12724 RIG-1 modulator 1 RIG-1 modulator 1 is useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV.
T14495 Baloxavir Baloxavir is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.
T12077 ML303 ML303 is an antagonist of pyrazolopyridine influenza virus nonstructural protein 1 (NS1) (IC90 : 155 nM).
T8498 EiDD1931 EiDD1931 is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells,...
T8501 3-​Phenyl-​N-​[1-​(phenylmethyl)​-​4-​piperidinyl]​-tricyclo[3.3.1.13,​7]​decane-​1-​carboxamide 3-​Phenyl-​N-​[1-​(phenylmethyl)​-​4-​piperidinyl]​-tricyclo[3.3.1.13,​7]​decane-​1-​carboxamide with antiviral activity against Ebola vi...
T8502 N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide inhibiting the entry of Ebola virus in host cells by binding to the surface glycoprotein, the compound inhibite...
T2522 Peramivir Trihydrate Peramivir is a neuraminidase inhibitor (IC50: 0.09 nM) which prevents normal processing of virus particles such that virus particles are not released from infect...
Laninamivir octanoate
T9124CAS 203120-46-1
Laninamivir octanoate is a long acting influenza neuraminidase (NA) inhibitor which shows superior anti-influenza virus activity.
Theaflavin
T7602CAS 4670-05-7
Theaflavin is a polyphenolic flavonoid that has been found in black tea and has diverse biological activities, including antioxidant, anticancer, anti-inflammato...
Glabrone
TN1693CAS 60008-02-8
Glabrone shows antiviral activity against influenza virus.
Clemastanin B
TN1506CAS 112747-98-5
Clemastanin B has antioxidant and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and bl...
Cephaeline
TN1480CAS 483-17-0
Cephaeline was highly active against protected primary CLL cells (relative IC50's 35nM ) and acted by repressing HIF-1α± and disturbing intracellular redox hom...
Diphyllin
TN1103CAS 22055-22-7
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.
Nuezhenidic acid
TN1073CAS 183238-67-7
Nuezhenidic acid is a natural product, posseses inhibitory activities against influenza A virus.
Filixic acid ABA
TN1066CAS 38226-84-5
Filixic acid ABA exhibits inhibitory effects on neuraminidase of influenza virus H5N1 with IC50 as 29.57 ± 2.48 μM, it may have anti-influenza virus activity.
3,4'-Dihydroxyflavone
T8263CAS 14919-49-4
3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus[1].
T-1105
T7785CAS 55321-99-8
T-1105 is a broad-spectrum antiviral inhibitor.
Nucleozin
T7330CAS 341001-38-5
Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.
Soyasaponin II
TN2231CAS 55319-36-3
Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1.
Baloxavir marboxil
T6195CAS 1985606-14-1
Baloxavir marboxil is a novel cap-dependent endonuclease inhibitor for the treatment of influenza A and B virus infections.
Oseltamivir acid
T5186CAS 187227-45-8
Oseltamivir acid (GS4071) is a potent influenza virus neuraminidase inhibitor and the prodrug of GS4071.
Pimodivir
T4377CAS 1629869-44-8
Pimodivir, an influenza A virus polymerases inhibitor via oral, interacts with the viral PB2 subunit.
KIN1148
T4027CAS 1428729-56-9
KIN1148 is a novel small-molecule adjuvant that acts through the RIG-I pathway and IRF-3 transcription factor to stimulate inN/Ate immunity and protection follow...
Oseltamivir phosphate
T1486CAS 204255-11-8
Oseltamivir Phosphate is the phosphate salt of oseltamivir, a synthetic derivative prodrug of ethyl ester with antiviral activity. By blocking neuraminidases on ...
1,2,3,4,6-O-Pentagalloylglucose
T3794CAS 14937-32-7
1, 2, 3, 4, 6-Pentagalloylglucose and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-...
Zanamivir
T2529CAS 139110-80-8
Zanamivir is a guanido-neuraminic acid that is used to inhibit NEURAMINIDASE.
Rimantadine
T6642CAS 13392-28-4
Rimantadine (Flumadine) is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.
Arbidol hydrochloride
T0104CAS 131707-23-8
Arbidol (Umifenovir) hydrochloride, an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with host c...
Sanggenol A
TN2176CAS 174423-30-4
Sanggenol A shows neuroprotective activity on glutamate-induced cell death in HT22 cells, with EC50 values of 34.03 ± 7.71 μM. Sanggenol A inhibits influenza A...
Eleutheroside B1
TN2331CAS 16845-16-2
Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine gene...
CEF3 acetate(199727-62-3 free base)
TP1782LCAS TP1782L
CEF3 acetate corresponds to aa 13-21 of the influenza A virus M1 protein. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays es...
Laninamivir
T15707CAS 203120-17-6
Laninamivir is an effective inhibitor of influenza neuraminidase (NA) (IC50s: 0.90 nM, 1.83 nM, and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI...
CEF6 acetate(913545-15-0 free base)
TP1822LCAS TP1822L
CEF6 acetate is a HLA-B7 restricted influenza virus nucleoprotein epitope, belongs to the CEF control peptides. The CEF control peptides are 8-12 amino acids in ...
CBS1117
T8793CAS 959245-08-0
CBS1117 is a virus entry inhibitor (IC50 of 70 nM for influenza A virus, A/Puerto Rico/8/34 (H1N1)). It interferes with the hemagglutinin (HA)-mediated fusion ...
Shegansu B
TN5005CAS 291535-65-4
Shegansu B exhibits significant in vitro anti-influenza viral activity in MDCK cells.
Platyphyllonol
TN4810CAS 41137-85-3
Platyphyllonol-5-xylopyranoside is moderately active against KBNP-0028 (H9N2) avian influenza virus as compared with zanamivir.
Oplodiol
TN4716CAS 13902-62-0
Oplodiol exhibits noteworthy anti-plasmodial activity against Plasmodium falciparum strains. Oplodiol has a stimulative effect on significantly proliferation and...
Koaburaside
TN4392CAS 41653-73-0
Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have...
Asebotin
TN3461CAS 11075-15-3
Asebotin shows anti-influenza A virus activity, it also possesses potent antiviral activity (100% inhibition at the concentration of 1 ug /mL) against highly pat...
Dryocrassin ABBA
T4S1114CAS 12777-70-7
Dryocrassin ABBA is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities.
LNK754
T15770CAS 439153-64-7
LNK754 is a farnesyltransferase inhibitor. It is used for the treatment of cancer and Alzheimer's disease.
Laninamivir
T15707CAS 203120-17-6
Laninamivir is an effective inhibitor of influenza neuraminidase (NA) (IC50s: 0.90 nM, 1.83 nM, and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI...
Triazavirin
T8354CAS 928659-17-0
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.
Tunicamycin
T13229CAS 11089-65-9
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin inhibit...
Sodium copper chlorophyllin B
T12953CAS 28302-36-5
Sodium copper chlorophyllin B exerts antiviral activities against Influenza virus and HIV (IC50s of 50 to 100 μM).
S119-8
T12818CAS 443639-96-1
RN-18 antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G. RN-18 increases cellular A3G levels in a Vif-dependent manner and incr...
RIG-1 modulator 1
T12724CAS 1428729-63-8
RIG-1 modulator 1 is useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV.
Baloxavir
T14495CAS 1985605-59-1
Baloxavir is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.
ML303
T12077CAS 1638211-04-7
ML303 is an antagonist of pyrazolopyridine influenza virus nonstructural protein 1 (NS1) (IC90 : 155 nM).
EiDD1931
T8498CAS 3258-02-4
EiDD1931 is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells,...
3-​Phenyl-​N-​[1-​(phenylmethyl)​-​4-​piperidinyl]​-tricyclo[3.3.1.13,​7]​decane-​1-​carboxamide
T8501CAS 1252187-41-9
3-​Phenyl-​N-​[1-​(phenylmethyl)​-​4-​piperidinyl]​-tricyclo[3.3.1.13,​7]​decane-​1-​carboxamide with antiviral activity against Ebola vi...
N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide
T8502CAS 314030-54-1
N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide inhibiting the entry of Ebola virus in host cells by binding to the surface glycoprotein, the compound inhibite...
Peramivir Trihydrate
T2522CAS 1041434-82-5
Peramivir is a neuraminidase inhibitor (IC50: 0.09 nM) which prevents normal processing of virus particles such that virus particles are not released from infect...