GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.

Cat. No.	Product name	CAS No.	Purity
T11684	Isoguvacine hydrochloride	68547-97-7	98%
T11684	Isoguvacine hydrochloride is a GABA receptor agonist.
T6355	(R)-baclofen	69308-37-8	98%
T6355	(R)-baclofena, a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.
T14571	Bifenazate	149877-41-8	98%
T14571	Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.
T7822	Pagoclone	133737-32-3	98%
T7822	Pagoclone is a GABA receptor agonist and can be used for studies on the treatment of stuttering, panic disorder, and generalized anxiety. Pagoclone is a partial ...
T4688	Pipequaline hydrochloride	80221-58-5	98%
T4688	Pipequaline is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure t...
T6507	Gabapentin hydrochloride	60142-95-2	98%
T6507	Gabapentin HCl is a GABA analogue, used to treat seizures and neuropathic pain.
TN1325	(2S)-6-Prenylnaringenin	68236-13-5	98%
TN1325	6-Prenylnaringenin is an isomer of the potent phytoestrogen, 8-prenylnaringenin.
T2749	Ginkgolide A	15291-75-5	98%
T2749	Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inf...
T7064	Valproic Acid	99-66-1	98%
T7064	Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various mol...
T26600	Alpidem	82626-01-5	98%
T26600	Alpidem is an anxiolytic drug from the imidazopyridine family. Alpidem does not produce sedative effects at normal doses, and is instead used specifically for th...
T0024	Primidone	125-33-7	98%
T0024	Primidone is an anticonvulsant of the pyrimidinedione class.
TQ0023	Lorediplon	917393-39-6	98%
TQ0023	Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.
T2S1814	P-Hydroxybenzaldehyde	123-08-0	98%
T2S1814	1. 4-Hydroxybenzaldehyde shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity, and its inhibitory ac...
T4440	Saclofen	125464-42-8	98%
T4440	Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7....
TQ0040	ONO-8590580	1802661-73-9	98%
TQ0040	ONO-8590580 is a negative allosteric modulator of GABAA α5.
T12207	NEO 376	496921-73-4	98%
T12207	NEO 376 is a selective 5-HT1 receptor, GABA receptor and dopamine receptor modulator, showing anti-psychotic actively.
T36520	COR659	544450-68-2	98%
T36520	COR659 is a GABAB positive allosteric modulator (PAM) . COR659 suppresses alcohol and chocolate self-administration in rats[1]. COR659 apparently exerts its effe...
T16811	RWJ-51204	205701-85-5	98%
T16811	RWJ-51204 is A potent and selective adenosine A2A receptor antagonist. RWJ-51204 is a partial agonist of GABA(A) receptor (IC50: 0.2-2 nM), which has neuroprotec...
T3S2100	(-)-Securinine	5610-40-2	98%
T3S2100	(-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist.
TQ0119	Cirsimaritin	6601-62-3	98%
TQ0119	Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine ...