Home Tools
Log in
Cart

GABA Receptor

The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system. There are two classes of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors.
Cat. No. Product name CAS No. Purity Chemical Structure
TN1717 Guvacine 498-96-4 98%
Guvacine can enhance the inhibition of spinal neurones by GABA.
T11686 Isotanshinone I 20958-17-2 98%
Isotanshinone I with IC50s of 1.13 μM and 0.432 μM for α-glucosidase and AGE, respectively. Isotanshinone I has inhibitory activity against α-glucosidase and for...
T12043 (-)-Bicuculline methobromide 73604-30-5 98%
(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .
TN5147 Tilifodiolide 126724-95-6 98%
Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreas...
T16794 RO 4938581 883093-10-5 98%
RO 4938581 is an effective and selective agonist of GABAA α5 inverse (Ki: 4.6 nM for GABAA α5β3γ2a, and shows a lower affinity at α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki, ...
T14938 CGP 36742 123690-78-8 98%
CGP 36742 is a selective antagonist of the GABAB receptor that can penetrate the blood-brain barrier after peripheral administration (IC50: 32 μM). It is useful ...
TN3351 Aflatrem 70553-75-2 98%
Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocam...
T16717 Radequinil 219846-31-8 98%
Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).
T21793 CGP 35348 123690-79-9 98%
CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after n...
T28479 PZ-II-029 164025-44-9 98%
PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.
T16539 Piperazine citrate 144-29-6 98%
Piperazine Citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmi...
T8268 6,2'-Dihydroxyflavone 92439-20-8 98%
6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.
T32098L Homocarnosine acetate 98%
Homocarnosine acetate is a dipeptide unique to brain consisting of γ-aminobutyric acid (GABA) and histidine. Homocarnosine acetate has antioxidant and anti-infla...
T37190 L-Allylglycine 16338-48-0 98%
L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo...
T3173 DAA-1106 220551-92-8 98%
DAA1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine ...
T22616 Bretazenil 84379-13-5 98%
GABAA benzodiazepine site partial agonist
T77568 6,7-dimethylisatin 20205-43-0 98%
6,7-Dimethylisatin inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.
TN1308 6-Hydroxyflavanone 4250-77-5 98%
6-Hydroxyflavanone, a compound extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxyge...
T8193 α-Thujone 546-80-5 98%
Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
T5880 Aminooxyacetic acid hemihydrochloride 2921-14-4 98%
Aminooxyacetic acid hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme GABA-T.
Guvacine
TN1717
Guvacine can enhance the inhibition of spinal neurones by GABA.
Isotanshinone I
T11686
Isotanshinone I with IC50s of 1.13 μM and 0.432 μM for α-glucosidase and AGE, respectively. Isotanshinone I has inhibitory activity against α-glucosidase and for...
(-)-Bicuculline methobromide
T12043
(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .
Tilifodiolide
TN5147
Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreas...
RO 4938581
T16794
RO 4938581 is an effective and selective agonist of GABAA α5 inverse (Ki: 4.6 nM for GABAA α5β3γ2a, and shows a lower affinity at α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki, ...
CGP 36742
T14938
CGP 36742 is a selective antagonist of the GABAB receptor that can penetrate the blood-brain barrier after peripheral administration (IC50: 32 μM). It is useful ...
Aflatrem
TN3351
Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocam...
Radequinil
T16717
Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).
CGP 35348
T21793
CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after n...
PZ-II-029
T28479
PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.
Piperazine citrate
T16539
Piperazine Citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmi...
6,2'-Dihydroxyflavone
T8268
6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.
Homocarnosine acetate
T32098L
Homocarnosine acetate is a dipeptide unique to brain consisting of γ-aminobutyric acid (GABA) and histidine. Homocarnosine acetate has antioxidant and anti-infla...
L-Allylglycine
T37190
L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo...
DAA-1106
T3173
DAA1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine ...
Bretazenil
T22616
GABAA benzodiazepine site partial agonist
6,7-dimethylisatin
T77568
6,7-Dimethylisatin inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.
6-Hydroxyflavanone
TN1308
6-Hydroxyflavanone, a compound extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxyge...
α-Thujone
T8193
Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
Aminooxyacetic acid hemihydrochloride
T5880
Aminooxyacetic acid hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme GABA-T.
1 2 3 4 5 6 7 8 9 10