TN1717 |
Guvacine
|
498-96-4
|
98%
|
|
Guvacine can enhance the inhibition of spinal neurones by GABA.
|
T11686 |
Isotanshinone I
|
20958-17-2
|
98%
|
|
Isotanshinone I with IC50s of 1.13 μM and 0.432 μM for α-glucosidase and AGE, respectively. Isotanshinone I has inhibitory activity against α-glucosidase and for...
|
T12043 |
(-)-Bicuculline methobromide
|
73604-30-5
|
98%
|
|
(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .
|
TN5147 |
Tilifodiolide
|
126724-95-6
|
98%
|
|
Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreas...
|
T16794 |
RO 4938581
|
883093-10-5
|
98%
|
|
RO 4938581 is an effective and selective agonist of GABAA α5 inverse (Ki: 4.6 nM for GABAA α5β3γ2a, and shows a lower affinity at α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki, ...
|
T14938 |
CGP 36742
|
123690-78-8
|
98%
|
|
CGP 36742 is a selective antagonist of the GABAB receptor that can penetrate the blood-brain barrier after peripheral administration (IC50: 32 μM). It is useful ...
|
TN3351 |
Aflatrem
|
70553-75-2
|
98%
|
|
Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocam...
|
T16717 |
Radequinil
|
219846-31-8
|
98%
|
|
Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).
|
T21793 |
CGP 35348
|
123690-79-9
|
98%
|
|
CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after n...
|
T28479 |
PZ-II-029
|
164025-44-9
|
98%
|
|
PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.
|
T16539 |
Piperazine citrate
|
144-29-6
|
98%
|
|
Piperazine Citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmi...
|
T8268 |
6,2'-Dihydroxyflavone
|
92439-20-8
|
98%
|
|
6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.
|
T32098L |
Homocarnosine acetate
|
|
98%
|
|
Homocarnosine acetate is a dipeptide unique to brain consisting of γ-aminobutyric acid (GABA) and histidine. Homocarnosine acetate has antioxidant and anti-infla...
|
T37190 |
L-Allylglycine
|
16338-48-0
|
98%
|
|
L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo...
|
T3173 |
DAA-1106
|
220551-92-8
|
98%
|
|
DAA1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine ...
|
T22616 |
Bretazenil
|
84379-13-5
|
98%
|
|
GABAA benzodiazepine site partial agonist
|
T77568 |
6,7-dimethylisatin
|
20205-43-0
|
98%
|
|
6,7-Dimethylisatin inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.
|
TN1308 |
6-Hydroxyflavanone
|
4250-77-5
|
98%
|
|
6-Hydroxyflavanone, a compound extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxyge...
|
T8193 |
α-Thujone
|
546-80-5
|
98%
|
|
Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
|
T5880 |
Aminooxyacetic acid hemihydrochloride
|
2921-14-4
|
98%
|
|
Aminooxyacetic acid hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme GABA-T.
|