zebrafish

Zebrafish Kisspeptin-1 acetate (1071873-79-4 Free base) comprises the core sequence of the zebrafish neuropeptide kisspeptin-1, regulating dopaminergic neurons in the zebrafish forebrain and fear responses.

Kisspeptin-10, a neuropeptide present in the brains, ovaries, and testes of zebrafish, plays a critical role in gonadal development and steroid expression. At a concentration of 10 ng/ml, it enhances the mRNA levels for the luteinizing hormone (Lh) receptor and both progestin receptor a (Pra) and Prb in zebrafish ovarian follicles. In female goldfish, doses of 0.1 and 1 µg/g of Kisspeptin-10 elevate serum levels of luteinizing hormone, with no similar effect observed in male goldfish.

Ac-FEID-CMK, a potent peptide inhibitor derived from zebrafish-specific GSDMEb, effectively reduces mortality and kidney injury during septic shock by inhibiting pyroptosis and mitigating acute kidney injury (AKI) in vivo. Additionally, it suppresses the caspy2-mediated noncanonical inflammasome pathway [1].

Ac-FEID-CMK TFA is a selective zebrafish GSDMEb-derived peptide inhibitor that reduces mortality and renal injury in infectious shock. It inhibits pyroptosis in vivo, attenuates septic AKI (acute kidney injury), and inhibits the caspy2-mediated atypical inflammatory vesicle pathway.

MHLWAAK TFA, an antioxidant peptide derived from the pancreatin hydrolysate of C-phycocyanin, exhibits potent DPPH and ABTS radical scavenging properties. It effectively shields zebrafish larvae against oxidative damage induced by H2O2 [1].

MHLWAAK, an antioxidant peptide derived from pancreatin hydrolysate of C-phycocyanin, exhibits potent DPPH and ABTS radical scavenging capabilities. It effectively shields zebrafish larvae against H2O2-induced oxidative damage [1].

MDYYFEER TFA, an antioxidant peptide derived from pancreatin hydrolysate of C-phycocyanin, exhibits potent DPPH and ABTS radical scavenging capability. This compound effectively shields zebrafish larvae against oxidative damage induced by H2O2 [1].

MDYYFEER, an antioxidant peptide derived from pancreatin hydrolysate of C-phycocyanin, exhibits strong DPPH and ABTS radical scavenging activities. It has been demonstrated to protect zebrafish larvae against oxidative damage induced by H2O2 [1].

MAQAAEYYR TFA, an antioxidant peptide derived from the pancreatin hydrolysate of C-phycocyanin, exhibits potent DPPH and ABTS radical scavenging properties. It confers protection to zebrafish larvae against oxidative damage induced by H2O2 [1].

MAQAAEYYR, an antioxidant peptide derived from the pancreatin hydrolysate of C-phycocyanin, exhibits potent scavenging activities against DPPH and ABTS radicals. It also confers protection to zebrafish larvae against oxidative damage induced by H2O2 [1].

FGGH is a water-soluble peptide probe that enables highly sensitive sequential detection of Cu2+ and S2- through fluorescence and colorimetric methods, with limits of detection (LOD) of 1.42 nM for Cu2+ and 22.2 nM for S2-. It allows imaging of these ions in live cells and zebrafish models with low cytotoxicity. FGGH is applicable for in vivo imaging and environmental pollution monitoring research.

soVIRIP is an antiviral peptide with an IC50 of 1.2 μM against HIV-1. It binds to the HIV-1 GP41 fusion peptide, thereby inhibiting viral fusion and blocking entry into host cells. soVIRIP demonstrates broad-spectrum anti-HIV-1 activity and shows no toxicity in zebrafish models. It is applicable in viral infection research.