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Search Results for " tachycardia "

16

Compounds

Cat No. Product Name Synonyms Targets
T23310 SB-203186 hydrochloride 5-HT Receptor
SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist
T10634 Bunaftide Bunaphtide,Meregon,Bunaftine Others
Bunaftide (Bunaphtid) has antiarrhythmic effects and inhibits aconitine-induced ventricular tachycardia.
T28540 Ripisartan UP 269-6,UP-2696,UP 2696,UP-269-6,UP269-6 RAAS
Ripisartan (UP-269-6) is a potent and specific angiotensin II receptor antagonist that inhibits angiotensin II-mediated sympathetic tachycardia responses.
T1158 Phenoxybenzamine hydrochloride NCI-c01661,NSC 37448,Phenoxybenzamine HCl CaMK , Adrenergic Receptor
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non...
T1439 Lacidipine SN-305,GX-1048,GR-43659X Apoptosis , Calcium Channel , Reactive Oxygen Species
Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specifi...
T4550 Ajmaline Cardiorythmine,Raugalline,Tachmalin,(+)-Ajmaline Sodium Channel
Ajmaline (Cardiorythmine) is a class Ia anti-arrhythmic compound that is widely used for the diagnosis of Brugada syndrome and the acute treatment of atrial or ventricular tachycardia. Ajmaline inhibits cardiac Kv1.5 and...
T15257 Etripamil MSP-2017,(-)-MSP-2017 Calcium Channel
Etripamil (MSP-2017) displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells...
T0976 Propoxur Aprocarb,Propoxure,Baygon AChR , Antifungal
Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red b...
T21391 Flecainide Tambocor,Apocard,Flecainida,Flecainidum
Flecainide acetate is a class Ic antiarrhythmic agent, it is used to treat a variety of cardiac arrhythmias including paroxysmal atrial fibrillation, paroxysmal supraventricular tachycardia, and ventricular tachycardia. ...
T14153 Aladorian ARM036 Others
Aladorian (ARM036) is a benzothiazepine derivative and it has anti-arrhythmia effect. Aladorian is used for the research of heart failure and catecholaminergic polymorphic ventricular tachycardia[1][2].
T21424 Disopyramide phosphate SC13957,SC 13957,SC-13957
Disopyramide, a sodium channel blocker in the Class of 1a anti-arrhythmic agent, is used in the treatment of Ventricular Tachycardia. Disopyramide has a negative inotropic effect on the ventricular myocardium, resulting ...
T36561 (3S)-hydroxy Quinidine
(3S)-hydroxy Quinidine is an active quinidine metabolite. Quinidine, an antiarrhythmic agent, undergoes rapid first-pass metabolism by the cytochrome P450 (CYP) isoforms CYP3A4, CYP2C9, CYP2E1, and CYP3A5, with CYP3A4 be...
T68639 Ciprostene (free base)
Ciprostene (free base) is a synthetic, chemically stable analog of prostacyclin (PGI2). In animal models, administration of ciprostene resulted in dose-dependent hypotension, tachycardia, and inhibition of ex vivo ADP-in...
T36732 Ciprostene (calcium salt)
Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2. Ciprostene exhibits biological activity similar to PGI2, but is 30-fold less potent. In patas monkeys, ciprostene induces hypotension a...
T69119 Disopyramide HCl
Disopyramide HCl is the salt form of Disopyramide, an antiarrhythmic medication used in the treatment of ventricular tachycardia. It is a sodium channel blocker and therefore classified as a Class 1a anti-arrhythmic agen...
T70077 Fadolmidine HCl
Fadolmidine, also known as MPV-2426, is a novel and potent alpha2 -adrenoceptor (alpha2) -AR) agonist developed for spinal analgesia. Fadolmidine displayed high affinity and full agonist efficacy at all three human alpha...
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