serum amyloid a protein

Expression system: E. coli
Length: 19-130, Full Length of Mature Protein
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 1-90, Partial
Activity: Not Tested

Expression system: E. coli
Length: 1-90, Partial
Activity: Not Tested

Expression system: E. coli
Length: 19-129, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1-110, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-112, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 20-122, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 20-122, Partial
Activity: Not Tested

Expression system: P. pastoris (Yeast)
Length: 20-122, Partial
Activity: Not Tested

Expression system: E. coli
Length: 19-122, Full Length of Mature Protein
Activity: Cell Activity

Expression system: E. coli
Length: 20-122, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 20-122, Partial
Activity: Not Tested

Serum Amyloid A1 Protein (SAA1) is an acute phase apolipoprotein reactant that is produced predominantly by hepatocytes and is under the regulation of inflammatory cytokines. SAA is produced mainly in the liver and circulates in low levels in the blood. SAA may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA also functions as an apolipoprotein of the HDL complex. The SAA cleavage product designated amyloid protein A is deposited systemically as amyloid in vital organs such as the liver, spleen, and kidneys in chronic inflammatory diseases patients. These deposits are extremely insoluble and resistant to proteolysis; they disrupt tissue structure and compromise performance.

Serum amyloid A-2 protein (SAA2) belongs to the SAA family. It expressed by the liver and secreted in plasma. SAA2 functions as major acute phase reactant and could works as apolipoprotein of the HDL complex. Increased levels of A-SAA in serum are indicative of inflammatory disease. When highly expressed, SAA can displace ApoA1 as the major apolipoprotein in HDL complexes, weakening the function of HDL as a reverse (lipid clearing) cholesterol transporter. A highly charged region of SAA2 and SAA1 (aa 36-68) contains putative fibronectin- and laminin-binding motifs. This region also binds heparin sulfate proteoglycans at mildly acidic pH and promotes aggregation of A-SAA.

Expression system: HEK293 Cells
Length: 21-224, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 20-223, Full Length of Mature Protein
Activity: ELISA

Expression system: HEK293 Cells
Length: 1-381, Full Length
Activity: Not Tested