sc9

SC-9 is a protein kinase C activator.

PNSC928 is an inhibitor of the CtBP2-p300 interaction, with an IC50 of 23.60 µM. It can reverse the expression of pro-inflammatory cytokines induced by Lipopolysaccharides in RAW264.7 cells. Additionally, PNSC928 has the potential to ameliorate acute respiratory distress syndrome (ARDS) in mice.

NSC90616 is a compound that rescues mutant p53 [1].

SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activities

SC912 is an AR-V7 inhibitor with an IC50 of 0.36 μM. It directly binds to AR-FL and AR-V7 proteins, preventing their nuclear localization and chromatin binding. SC912 can exert anticancer effects by suppressing cell proliferation, inducing cell cycle arrest, and promoting apoptosis.

Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.

1-Naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe for sensing thermotropic microenvironmental changes of pluronic F127 in aqueous media.

Ornidazole (Tiberal) is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing action.

3-Phenylpropanal (Phenylpropyl aldehyde) is a RIFM flavor ingredient and can be used to make perfume.3-Phenylpropanal is the main ingredient in acaricides.3-Phenylpropanal can be used as a fly attractant.3-Phenylpropanal can be used as an insecticide.

Hydroquinone diacetate (NSC-9277) is an OH• inibitor with IC50 of 7.59 μM.

Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a corticosteroid with anti-inflammatory properties that promotes the polarization of M1 to M2 macrophages by reducing the secretion of pro-inflammatory cytokines, and is utilized in research on keloids and rheumatoid arthritis.

Fluorogestone acetate shows high potency with a short duration of activity and is physiologically similar to progesterone. FGA is approximately 20-25 times more potent than progesterone.

3-Aminopropyltriethoxysilane (APTES) immobilizes biomolecules on silicon-based materials, such as Si3N4, while acting as a spacer to provide spatial freedom and higher activity for immobilized biomolecules to build analytical platforms for biosensing, recognition and more.

5-Hydroxytryptophan (NSC-92523) is a metabolite of tryptophan and a direct precursor of serotonin. It is a substrate of aromatic amino acid decarboxylase and can be used to induce depression models.

3-Methoxybenzoic acid (NSC 27014) is a food additive,and has antibacterial activity.

6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC-95682) is an inhibitor of IRE-1α with an IC50 value of 0.08 μM.

DL-Phenylalanine, a phenylalanine derivative, exhibits antifungal activity against Aspergillus flavus and antibacterial activity against Bacillus cereus and Escherichia coli.

Methylthiouracil is a thiourea-class antithyroid agent that inhibits the synthesis of thyroid hormones and is commonly used to treat hyperthyroidism. Studies have shown that Methylthiouracil can also suppress the production of TNF-α and IL-6, as well as inhibit the activation of NF-κB and ERK1/2. It can be used to induce hyperlipidemia and neurological disorder models.

Canrenone (SC14266) is an aldosterone antagonist with potassium-sparing diuretic activity.

Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase 3 activation.

2,4-D-methyl is a carboxylesterase in herbicide bioactivation.

Apiole (NSC 9070), a phenylpropane volatile compound isolated from parsley, is a calcium channel inhibitor, a mixed-type inhibitor of the CYP1A subfamily, with antitumor activity, induces apoptosis, and inhibits human colon cancer cells by inducing G0/G1 cell cycle arrest.

1,2-Naphthoquinone inhibits urease in bacteria and plants, induces apoptosis in PBMC cells, and exhibits inhibitory activity against hiCE, hCE1, hAChE, and hBChE.

1,1'-Biphenyl, 2-iodo- is an agent of biochemical.