rat,human

Anti-Mouse/Rat/Human v-H-Ras Antibody (Y13-238) is an IgG2a antibody inhibitor derived from rats, targeting v-H-Ras in mice, rats, and humans.

Anti-Mouse/Rat/Human LRP1/CD91 Antibody (11H4) is an IgG1, κ antibody inhibitor derived from mice, targeting the LRP1/CD91 proteins in mice, rats, and humans.

Anti-Mouse/Rat/HumanPD-L1Antibody (368A.4H1) is a murine-derived IgG1, κ antibody inhibitor targeting PD-L1 in mice, rats, and humans.

Anti-Mouse/Rat/Human CD47/IAP Antibody (MIAP410) is a mouse-derived IgG1, κ antibody inhibitor targeting CD47/IAP in mice, rats, and humans.

Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5) is a monoclonal antibody targeting mouse/human/rat CCL2/MCP-1, capable of blocking the CCL2 signalling pathway, reversing the immunosuppressive microenvironment, enhancing chemotherapy sensitivity, reducing macrophage infiltration, and inhibiting latent HIV seeding. It is applicable for studying inflammatory diseases, viral infections, and cancers such as inflammatory bowel disease (IBD) and hepatocellular carcinoma (HCC).

Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A) is an IgG antibody inhibitor derived from American hamster, targeting ICOS/CD278 in mice, rats, monkeys, and humans.

Anti-Human/Mouse/Rat Amyloid-beta Antibody (MOAB-2) is an IgG2b, λ inhibitor derived from mice, targeting Amyloid-beta.

Anti-Human/Rat HER2 (neu) Antibody (7.16.4) is a mouse-derived IgG2a, κ monoclonal antibody inhibitor that targets human or rat HER2.

Anti-Human/Rat/Fish AChR Antibody (Mab35) is an IgG1 antibody inhibitor derived from rats, targeting AChR in humans, rats, and fish.

Anti-Mouse/Human/Rat/Monkey/Hamster/Canine/Bovine TGF-β Antibody (1D11.16.8) is an IgG antibody inhibitor targeting TGF-β in multiple species including mouse, human, rabbit, monkey, hamster, dog, and cow. For information on the isotype control, refer to Mouse IgG1 kappa, Isotype Control.

Anti-Mouse/Rat/Human Osteopontin/SPP1 Antibody (MPIIIB10) is a mouse-derived antibody that targets and inhibits mouse, rat, and human Osteopontin/SPP1. It significantly suppresses tumour growth in CT26 and MC38 mouse tumour models and attenuates VSMC migration.

Fremanezumab (TEV-48125) is a humanised monoclonal antibody targeting CGRP, capable of neutralising human (IC50=7.94 nM), mouse (IC50=19.6 nM) and rat CGRP, and is indicated for the prevention of migraine. Fremanezumab inhibits CGRP's vasodilatory effects in the basilar artery constriction segment and suppresses activation of A-δ and high-threshold (HT) neurons in the meningeal nociceptive system triggered by cortical spreading depression (CSD) in rats. In vitro, Fremanezumab counteracts CGRP's immunosuppressive effects on microglia and lymphocytes.

ABT-110 is a human monoclonal antibody targeting NGF/bNGF. It has been shown to alleviate established thermal and mechanical hypersensitivity reactions in a CFA rat model. ABT-110 is applicable for research on persistent or chronic inflammatory pain.

Anti-IL-12 p70 Antibody (20C2) is an anti-human IL-12 p70 monoclonal antibody of the IgG1 isotype, and it acts by suppressing the production of interferon-gamma. Anti-IL-12 p70 Antibody (20C2) is applicable for research studies investigating inflammatory conditions where IL-12 signaling contributes to disease pathogenesis. Anti-IL-12 p70 Antibody (20C2) is recommended to be paired with an appropriate isotype control, specifically Rat IgG1 kappa, Isotype Control.

Anti-IL-4 Antibody (MP4-25D2) is a rat IgG1, κ chimeric antibody that targets human IL-4. The recommended isotype control for Anti-IL-4 Antibody (MP4-25D2) is Rat IgG1 kappa, Isotype Control.

XOMA-213 (LFA-102; X213) is a human monoclonal antibody (mAb) that specifically targets the PRLR/Prolactin Receptor. It inhibits hPRL-dependent growth of BaF3/hPRLR cells with an EC50 of 0.5 μg/mL. In models such as the Nb2-11-luc xenograft mouse and the DMBA-induced rat breast cancer model, XOMA-213 effectively suppresses PRLR signaling and tumor growth. This compound is applicable in research focused on breast cancer, hyperprolactinemia, and prostate cancer.

The Anti-CD44 Antibody (Hermes-1) is a chimeric rat-derived IgG2a, κ antibody targeting human CD44. The isotype control for the Anti-CD44 Antibody (Hermes-1) is RatIgG2akappa, Isotype Control.

Anti-NGF/bNGF Antibody (AS2886401-00) is a human monoclonal antibody (mAb) targeting NGF/bNGF. It inhibits intracellular calcium (Ca2+) influx and provides sustained analgesic effects during movement in an osteoarthritis (OA) rat model. This antibody is applicable for research in osteoarthritis.