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  • Potassium Channel
    (332)
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Results for "

potassiumchannel

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    340
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    39
    TargetMol | Peptide_Products
  • Dye Reagents
    2
    TargetMol | Dye_Reagents
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    62
    TargetMol | Natural_Products
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    5
    TargetMol | Disease_Modeling_Products
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    2
    TargetMol | Inhibitors_Agonists
Nigericin sodium salt
T309228643-80-3
Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which inhibits Golgi function and suppresses the growth of Gram-positive bacteria.
  • $31
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Ursodeoxycholic acid
Ursodiol, UDCA
T0700128-13-2
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.
  • $30
In Stock
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Reserpine
Serpivite, Serpasil, Serpalan
T079150-55-5
Reserpine (Serpalan) is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
  • $34
In Stock
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Tannic acid
Gallotannic acid
T08011401-55-4
Tannic acid (Gallotannic acid) is a novel hERG channel blocker.
  • $41
In Stock
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Chenodeoxycholic acid
Chenodiol, CDCA
T0847474-25-9
Chenodeoxycholic acid (CDCA) is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.
  • $30
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Taurocholic acid sodium salt hydrate
Taurocholic Acid sodium hydrate, Sodium taurocholate hydrate
T1138345909-26-4
Taurocholic acid sodium salt hydrate (Sodium taurocholate hydrate), formed by the conjugation of taurine with cholic acid, is the primary ingredient in the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is employed as a cholagogue and choleretic.
  • $42
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Isosteviol
(-)-Isosteviol
T333227975-19-5
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and steviolbioside, have many biological activities, such as reducing blood glucose, lowering blood pressure, anti-inflammation, anti-tumor, anti-diarrhea, antibacterium, immunoregulation, etc.
  • $41
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2,2,2-Trichloroethanol
T37709115-20-8
2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4). It activates a nonclassical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery [1]. [1]. Nikhil K Parelkar, et al. 2,2,2-trichloroethanol Activates a Nonclassical Potassium Channel in Cerebrovascular Smooth Muscle and Dilates the Middle Cerebral Artery. J Pharmacol Exp Ther. 2010 Mar;332(3):803-10.
  • $29
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Cholesterol myristate
Cholesteryl tetradecanoate, Cholesteryl myristate
T80401989-52-2
Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the GABAA receptor, nicotinic acetylcholine receptor, and the inward-rectifier potassium ion channel.
  • $29
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Dronedarone
SR 33589
T7056141626-36-0
Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
  • $40
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Paederosidic acid methyl ester
T3S0870122413-01-8
Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.
  • $55
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Atpenin A5
T9714119509-24-9
Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM), as well as an effective mKATP channel agonist and cardioprotective agent [1].
  • $255
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O-Nornuciferine
TN10923153-55-7
O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.
  • $81
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Hypophyllanthin
TN175733676-00-5
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
  • $48
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Ecdysone
TN39103604-87-3
Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signaling through Ecdysone receptor isoform B1 is required cell autonomously for the muscle death.
  • $103
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Thevetin B
TN514127127-79-3
Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
  • $2,029
7-10 days
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20(S)-Ginsenoside Rg3
S-Ginsenoside Rg3, Rg3, Ginsenoside Rg3, 20S-Ginsenoside Rg3, 20(S)-Ginsenoside-Rg3
T340214197-60-5
20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the proliferation of human umbilical vein endothelial cells(HUVEC) and has anti-angiogenesis activities.
  • $32
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Quinidine
T793856-54-2
Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.
  • $33
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Chlorahololide D
TN5335943136-39-8
Chlorahololide D is a natural lindane-type sesquiterpene dimer and selective potassium channel blocker that stimulates reactive oxygen species ROS levels to cause cell cycle arrest in the G2 phase, modulates Bcl-2 and Bax and FAK, thereby inhibiting MCF-7 cell growth and triggering apoptosis. Chlorahololide D inhibits tumor proliferation, migration and angiogenesis in in vivo experiments and has anti-breast cancer potential.
  • $229
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1,8-Cineole
T1714470-82-6
Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.
  • $35
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Actein
T719018642-44-9
Actein has a stimulatory effect on osteoblastic bone formation or has potential activity against osteoporosis, it also can prevent oxidative damage to osteoblasts in osteoporotic patients. Actein's ability to pathways involved in lipid disorders and carci
  • $129
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Asebogenin
TN3460520-42-3
Asebogenin is a compound fractionated from Salvia miltiorrhiza with antifungal activity, inhibition of GPVI-induced platelet reactions, and inhibition of NET formation induced by pro-inflammatory stimuli.
  • $653
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Cicutoxin
TN9108505-75-9
Cicutoxin is a convulsant compound. It inhibits Na+ and K+ channels and suppresses the γ-aminobutyric acid pathway. As a potent GABA antagonist, Cicutoxin induces recurrent seizures and exhibits cholinergic activity. Its primary targets are the brain and skeletal muscles. Cicutoxin can be isolated from [Cicuta maculata] and [Cicuta douglasii].
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Quinidine hydrochloride monohydrate
T02666151-40-2
Quinidine hydrochloride monohydrate is an optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. It prolongs cellular action potential and decreases automaticity. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
  • $33
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