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Cat No. | Product Name | Synonyms | Targets |
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T2052 | KY02111 | Wnt/beta-catenin | |
KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC. | |||
T2437 | O4I2 | O-4I2,O4I2 | OCT |
O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts. | |||
T8647 | BCH001 | DNA/RNA Synthesis | |
BCH001 is a specific small-molecule inhibitor of PAPD5. | |||
T2040 | OAC1 | BAS 00287861 | OCT |
OAC1 (BAS 00287861) is a compound activating Octamer-binding transcription factor 4 (Oct4). It enhances the iPSC reprogramming efficiency and accelerates the reprogramming process. | |||
T1725 | Y-27632 dihydrochloride | Y-27632 2HCl | ROCK , Apoptosis |
Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells. | |||
T16287 | Neurodazine | DNA Methyltransferase | |
Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.Neurodazine promotes differentiation by activating Wnt and Shh signaling. | |||
T2019 | OAC2 | OCT | |
OAC2 is an Oct4 activator which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibrobl... | |||
T3684 | CP21R7 | CP21 | GSK-3 , PKC |
CP21R7 (CP21) is an effective and specific GSK3β inhibitor. It is used as an activator of stem cells prior to the induction of differentiation of stem cells to smooth muscle and endothelial cells. CP21R7 can be combined ... | |||
TP1828 | N-Acetyl-Ser-Asp-Lys-Pro | RAAS | |
Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethalit... | |||
T22814 | GSA-10 | Hedgehog/Smoothened | |
Smoothened (Smo) receptor agonist | |||
T23271 | RSC-133 | Others | |
promotes the reprogramming of human somatic cells to pluripotent stem cells | |||
T32416 | KP-1 | KP 1,KP1,Kyoto Probe 1 | |
KP-1 is a selective fluorescent probe for labeling human pluripotent stem cells. | |||
T33652 | Neurodazole | ||
Neurodazole is a neurogenic inducer for converting pluripotent P19 cells into electrophysiologically active neurons. | |||
TP2339 | Goralatide | ||
Goralatide, isolated from fetal calf bone marrow, exerts a high inhibitory activity on the proliferation of hematopoietic pluripotent stem cells. | |||
T36301 | PluriSIn #2 | ||
PluriSIn #2 acts as a selective transcriptional inhibitor of topoisomerase II α (TOP2A) and effectively eliminates undifferentiated human pluripotent stem cells (hPSCs)[1]. | |||
T13769 | TA-316 | Megakaryocytes/platelets inducing agent | Others |
Megakaryocytes/platelets inducing agent being useful in treating diseases involving thrombopenia. Megakaryocytes/platelets inducing agent is an inducing agent for megakaryocytes and/or platelets from pluripotent stem cel... | |||
T70520 | TWS-119 | ||
TWS-119 is an inhibitor of glycogen synthase kinase-3β (GSK-3β) that induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESCs). | |||
T81698 | NBD-LLLLpY | ||
NBD-LLLLpY is a peptide synthesized enzymatically within the nucleus to selectively target and eliminate human induced pluripotent stem cells (hiPSCs). | |||
T82642 | Cyclo(RGDfK(Mal)) | ||
Cyclo(RGDfK(Mal)), a pentapeptide, enhances the attachment and infiltration of human pluripotent stem cells and is utilized in three-dimensional stem cell culture and expansion [1]. | |||
T72244 | CBB1007 trihydrochloride | ||
CBB1007 trihydrochloride is a cell-permeable amidino-guanidinium compound that acts as a potent, reversible and substrate competitive LSD1 selective inhibitor (IC50 = 5.27 μM for hLSD1). IC50 Value: 5.27 uM ... | |||
T72388 | CBB1007 hydrochloride | ||
CBB1007 HCl is a cell-permeable amidino-guanidinium compound identified as a potent, reversible, and substrate-competitive inhibitor of LSD1 (IC50 = 5.27 μM for hLSD1). It effectively inhibits LSD1-mediated demethylation... | |||
T76068 | Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA | ||
Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA (Cyclo RGDfC) TFA, a cyclic RGD peptide, displays a high affinity for αvβ3 integrin, effectively disrupting cell-integrin interactions. It suppresses pluripotent marker expression in embr... | |||
T75752 | N-Acetyl-Ser-Asp-Lys-Pro acetate | ||
N-Acetyl-Ser-Asp-Lys-Pro (Ac-SDKP) acetate, a specific substrate for the N-terminal active site of angiotensin-converting enzyme (ACE), functions as a natural inhibitor of pluripotent hematopoietic stem cell proliferatio... | |||
T35541 | Lipoxygenin | ||
Lipoxygenin is an inhibitor of 5-lipoxygenase (5-LO) with an IC50value of 5 μM for inhibition of 5-LO product synthesis in isolated human granulocytes stimulated with the cation ionophore A23187 .1It inhibits hedgehog-de... | |||
T78520 | CYT296 | Others | |
CYT296 is a chromatin de-condensation agent that enhances the efficiency of induced pluripotent stem cell (iPSC) generation mediated by defined factors (OSKM) and promotes an open chromatin state in Mouse Embryonic Fibro... | |||
T35567 | BIX01294 (hydrochloride hydrate) | ||
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3)... | |||
T74247 | TPE-MI | ||
Tetraphenylethene maleimide (TPE-MI) serves as a thiol probe to assess unfolded protein levels and proteostasis within cells. It is particularly effective in identifying proteostasis imbalances in both induced pluripoten... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01084 | TrkA Protein, Human, Recombinant (His) | Human | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPJ-00051 | IL-3 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit... | |||
TMPK-00590 | IL-3 Protein, Human, Recombinant(E. coli) | Human | E. coli |
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit... | |||
TMPK-00077 | EPO/Erythropoietin Protein, Human, Recombinant | Human | HEK293 |
Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent potential, such as for cognition im... | |||
TMPK-00049 | IL-3 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit... | |||
TMPK-00031 | IL-3 Protein, Human, Recombinant (His & Avi) | Human | E. coli |
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit... | |||
TMPK-00655 | IL-3 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit... | |||
TMPK-00033 | IL-3 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit... | |||
TMPK-00032 | IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | E. coli |
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit... | |||
TMPY-01118 | SLC27A4/FATP4 Protein, Human, Recombinant (His) | Human | HEK293 |
SLC27A4/ATG4B complex might act as a new potential therapeutic target of lung tumor chemotherapy. The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. Autism s... | |||
TMPJ-00639 | CD123 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | Human Cells |
CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the... | |||
TMPJ-00244 | IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, hFc & Avi), Biotinylated | Human | Human Cells |
CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the... | |||
TMPJ-00251 | IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His) | Mouse | Human Cells |
CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the... | |||
TMPJ-00040 | FGF-2 Protein, Human,Recombinant (Q65I, C96S, N111G) | Human | E. coli |
Fibroblast growth factors (FGF) are a family of heparin-binding secreted proteins that stimulate cell proliferation and differentiation in a wide variety of tissues. FGFs play important roles in diverse biological functi... | |||
TMPJ-00039 | FGF-2 Protein, Human, Recombinant (K128N) | Human | E. coli |
Fibroblast growth factors (FGF) are a family of heparin-binding secreted proteins that stimulate cell proliferation and differentiation in a wide variety of tissues. FGFs play important roles in diverse biological functi... | |||
TMPY-01759 | TrkA Protein, Human, Recombinant (aa 285-413, His) | Human | E. coli |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPY-03536 | TrkA Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPY-03712 | TrkA Protein, Canine, Recombinant (His) | Canine | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPH-01288 | Elongin-B Protein, Human, Recombinant (GST) | Human | E. coli |
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its... | |||
TMPY-04663 | TrkA Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPY-01083 | TrkA Protein, Human, Recombinant (His & hFc) | Human | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPY-03470 | TrkA Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPY-01760 | TrkA Protein, Human, Recombinant (aa 194-413, His) | Human | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPY-03711 | TrkA Protein, Canine, Recombinant (hFc) | Canine | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPY-03560 | TrkA Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPY-06967 | TrkA Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPY-04285 | TrkA Protein, Rat, Recombinant (His) | Rat | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... |
Cat No. | Product Name | ||
---|---|---|---|
L8110 | Reprogramming Compound Library | 1840 compounds | |
A unique collection of 1840 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening. | |||
L8000 | Stem Cell Differentiation Compound Library | 1213 compounds | |
A unique collection of 1213 stem cell differentiation signaling targeted compounds for high throughput and high content screening; | |||
L4010 | Bioactive Compounds Library Max | 22706 compounds | |
A collection of 22706 bioactive compounds for high-throughput screening, high-content screening, cell induction and target identification. |