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Search Results for " pluripotent "

Targets

27

Compounds

27

Recombinant Proteins

3

Libraries

Cat No. Product Name Synonyms Targets
T2052 KY02111 Wnt/beta-catenin
KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.
T2437 O4I2 O-4I2,O4I2 OCT
O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.
T8647 BCH001 DNA/RNA Synthesis
BCH001 is a specific small-molecule inhibitor of PAPD5.
T2040 OAC1 BAS 00287861 OCT
OAC1 (BAS 00287861) is a compound activating Octamer-binding transcription factor 4 (Oct4). It enhances the iPSC reprogramming efficiency and accelerates the reprogramming process.
T1725 Y-27632 dihydrochloride Y-27632 2HCl ROCK , Apoptosis
Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.
T16287 Neurodazine DNA Methyltransferase
Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.Neurodazine promotes differentiation by activating Wnt and Shh signaling.
T2019 OAC2 OCT
OAC2 is an Oct4 activator which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibrobl...
T3684 CP21R7 CP21 GSK-3 , PKC
CP21R7 (CP21) is an effective and specific GSK3β inhibitor. It is used as an activator of stem cells prior to the induction of differentiation of stem cells to smooth muscle and endothelial cells. CP21R7 can be combined ...
TP1828 N-Acetyl-Ser-Asp-Lys-Pro RAAS
Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethalit...
T22814 GSA-10 Hedgehog/Smoothened
Smoothened (Smo) receptor agonist
T23271 RSC-133 Others
promotes the reprogramming of human somatic cells to pluripotent stem cells
T32416 KP-1 KP 1,KP1,Kyoto Probe 1
KP-1 is a selective fluorescent probe for labeling human pluripotent stem cells.
T33652 Neurodazole
Neurodazole is a neurogenic inducer for converting pluripotent P19 cells into electrophysiologically active neurons.
TP2339 Goralatide
Goralatide, isolated from fetal calf bone marrow, exerts a high inhibitory activity on the proliferation of hematopoietic pluripotent stem cells.
T36301 PluriSIn #2
PluriSIn #2 acts as a selective transcriptional inhibitor of topoisomerase II α (TOP2A) and effectively eliminates undifferentiated human pluripotent stem cells (hPSCs)[1].
T13769 TA-316 Megakaryocytes/platelets inducing agent Others
Megakaryocytes/platelets inducing agent being useful in treating diseases involving thrombopenia. Megakaryocytes/platelets inducing agent is an inducing agent for megakaryocytes and/or platelets from pluripotent stem cel...
T70520 TWS-119
TWS-119 is an inhibitor of glycogen synthase kinase-3β (GSK-3β) that induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESCs).
T81698 NBD-LLLLpY
NBD-LLLLpY is a peptide synthesized enzymatically within the nucleus to selectively target and eliminate human induced pluripotent stem cells (hiPSCs).
T82642 Cyclo(RGDfK(Mal))
Cyclo(RGDfK(Mal)), a pentapeptide, enhances the attachment and infiltration of human pluripotent stem cells and is utilized in three-dimensional stem cell culture and expansion [1].
T72244 CBB1007 trihydrochloride
CBB1007 trihydrochloride is a cell-permeable amidino-guanidinium compound that acts as a potent, reversible and substrate competitive LSD1 selective inhibitor (IC50 = 5.27 μM for hLSD1). IC50 Value: 5.27 uM ...
T72388 CBB1007 hydrochloride
CBB1007 HCl is a cell-permeable amidino-guanidinium compound identified as a potent, reversible, and substrate-competitive inhibitor of LSD1 (IC50 = 5.27 μM for hLSD1). It effectively inhibits LSD1-mediated demethylation...
T76068 Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA
Cyclo(Arg-Gly-Asp-D-Phe-Cys) TFA (Cyclo RGDfC) TFA, a cyclic RGD peptide, displays a high affinity for αvβ3 integrin, effectively disrupting cell-integrin interactions. It suppresses pluripotent marker expression in embr...
T75752 N-Acetyl-Ser-Asp-Lys-Pro acetate
N-Acetyl-Ser-Asp-Lys-Pro (Ac-SDKP) acetate, a specific substrate for the N-terminal active site of angiotensin-converting enzyme (ACE), functions as a natural inhibitor of pluripotent hematopoietic stem cell proliferatio...
T35541 Lipoxygenin
Lipoxygenin is an inhibitor of 5-lipoxygenase (5-LO) with an IC50value of 5 μM for inhibition of 5-LO product synthesis in isolated human granulocytes stimulated with the cation ionophore A23187 .1It inhibits hedgehog-de...
T78520 CYT296 Others
CYT296 is a chromatin de-condensation agent that enhances the efficiency of induced pluripotent stem cell (iPSC) generation mediated by defined factors (OSKM) and promotes an open chromatin state in Mouse Embryonic Fibro...
T35567 BIX01294 (hydrochloride hydrate)
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3)...
T74247 TPE-MI
Tetraphenylethene maleimide (TPE-MI) serves as a thiol probe to assess unfolded protein levels and proteostasis within cells. It is particularly effective in identifying proteostasis imbalances in both induced pluripoten...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01084 TrkA Protein, Human, Recombinant (His) Human HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPJ-00051 IL-3 Protein, Mouse, Recombinant (His) Mouse Human Cells
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00590 IL-3 Protein, Human, Recombinant(E. coli) Human E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00077 EPO/Erythropoietin Protein, Human, Recombinant Human HEK293
Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent potential, such as for cognition im...
TMPK-00049 IL-3 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00031 IL-3 Protein, Human, Recombinant (His & Avi) Human E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00655 IL-3 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00033 IL-3 Protein, Human, Recombinant (hFc) Human HEK293
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00032 IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated Human E. coli
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPY-01118 SLC27A4/FATP4 Protein, Human, Recombinant (His) Human HEK293
SLC27A4/ATG4B complex might act as a new potential therapeutic target of lung tumor chemotherapy. The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. Autism s...
TMPJ-00639 CD123 Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the...
TMPJ-00244 IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, hFc & Avi), Biotinylated Human Human Cells
CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the...
TMPJ-00251 IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His) Mouse Human Cells
CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the...
TMPJ-00040 FGF-2 Protein, Human,Recombinant (Q65I, C96S, N111G) Human E. coli
Fibroblast growth factors (FGF) are a family of heparin-binding secreted proteins that stimulate cell proliferation and differentiation in a wide variety of tissues. FGFs play important roles in diverse biological functi...
TMPJ-00039 FGF-2 Protein, Human, Recombinant (K128N) Human E. coli
Fibroblast growth factors (FGF) are a family of heparin-binding secreted proteins that stimulate cell proliferation and differentiation in a wide variety of tissues. FGFs play important roles in diverse biological functi...
TMPY-01759 TrkA Protein, Human, Recombinant (aa 285-413, His) Human E. coli
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-03536 TrkA Protein, Mouse, Recombinant (His) Mouse HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-03712 TrkA Protein, Canine, Recombinant (His) Canine HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPH-01288 Elongin-B Protein, Human, Recombinant (GST) Human E. coli
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its...
TMPY-04663 TrkA Protein, Rabbit, Recombinant (His) Rabbit HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-01083 TrkA Protein, Human, Recombinant (His & hFc) Human HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-03470 TrkA Protein, Mouse, Recombinant (hFc) Mouse HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-01760 TrkA Protein, Human, Recombinant (aa 194-413, His) Human HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-03711 TrkA Protein, Canine, Recombinant (hFc) Canine HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-03560 TrkA Protein, Rat, Recombinant (hFc) Rat HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-06967 TrkA Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-04285 TrkA Protein, Rat, Recombinant (His) Rat HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TrkA Protein, Human, Recombinant (His)
TMPY-01084
Species: Human
Expression System: HEK293
IL-3 Protein, Mouse, Recombinant (His)
TMPJ-00051
Species: Mouse
Expression System: Human Cells
IL-3 Protein, Human, Recombinant(E. coli)
TMPK-00590
Species: Human
Expression System: E. coli
EPO/Erythropoietin Protein, Human, Recombinant
TMPK-00077
Species: Human
Expression System: HEK293
IL-3 Protein, Mouse, Recombinant (hFc)
TMPK-00049
Species: Mouse
Expression System: HEK293
IL-3 Protein, Human, Recombinant (His & Avi)
TMPK-00031
Species: Human
Expression System: E. coli
IL-3 Protein, Cynomolgus, Recombinant (His)
TMPK-00655
Species: Cynomolgus
Expression System: E. coli
IL-3 Protein, Human, Recombinant (hFc)
TMPK-00033
Species: Human
Expression System: HEK293
IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00032
Species: Human
Expression System: E. coli
SLC27A4/FATP4 Protein, Human, Recombinant (His)
TMPY-01118
Species: Human
Expression System: HEK293
CD123 Protein, Cynomolgus, Recombinant (His)
TMPJ-00639
Species: Cynomolgus
Expression System: Human Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, hFc & Avi), Biotinylated
TMPJ-00244
Species: Human
Expression System: Human Cells
IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His)
TMPJ-00251
Species: Mouse
Expression System: Human Cells
FGF-2 Protein, Human,Recombinant (Q65I, C96S, N111G)
TMPJ-00040
Species: Human
Expression System: E. coli
FGF-2 Protein, Human, Recombinant (K128N)
TMPJ-00039
Species: Human
Expression System: E. coli
TrkA Protein, Human, Recombinant (aa 285-413, His)
TMPY-01759
Species: Human
Expression System: E. coli
TrkA Protein, Mouse, Recombinant (His)
TMPY-03536
Species: Mouse
Expression System: HEK293
TrkA Protein, Canine, Recombinant (His)
TMPY-03712
Species: Canine
Expression System: HEK293
Elongin-B Protein, Human, Recombinant (GST)
TMPH-01288
Species: Human
Expression System: E. coli
TrkA Protein, Rabbit, Recombinant (His)
TMPY-04663
Species: Rabbit
Expression System: HEK293
TrkA Protein, Human, Recombinant (His & hFc)
TMPY-01083
Species: Human
Expression System: HEK293
TrkA Protein, Mouse, Recombinant (hFc)
TMPY-03470
Species: Mouse
Expression System: HEK293
TrkA Protein, Human, Recombinant (aa 194-413, His)
TMPY-01760
Species: Human
Expression System: HEK293
TrkA Protein, Canine, Recombinant (hFc)
TMPY-03711
Species: Canine
Expression System: HEK293
TrkA Protein, Rat, Recombinant (hFc)
TMPY-03560
Species: Rat
Expression System: HEK293
TrkA Protein, Cynomolgus, Recombinant (His)
TMPY-06967
Species: Cynomolgus
Expression System: HEK293
TrkA Protein, Rat, Recombinant (His)
TMPY-04285
Species: Rat
Expression System: HEK293
Cat No. Product Name
L8110 Reprogramming Compound Library

1840 compounds
A unique collection of 1840 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening.
L8000 Stem Cell Differentiation Compound Library

1213 compounds
A unique collection of 1213 stem cell differentiation signaling targeted compounds for high throughput and high content screening;
L4010 Bioactive Compounds Library Max

22706 compounds
A collection of 22706 bioactive compounds for high-throughput screening, high-content screening, cell induction and target identification.
TargetMol