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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
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Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
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Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
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Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Search Result

Search Results for " pathway "

Targets

Hippo pathway Others Wnt/beta-catenin

807

Compounds

298

Natural Products

1067

Recombinant Proteins

22

Libraries

Cat No. Product Name Synonyms Targets
T13345 Wnt pathway activator 2 Others , Wnt/beta-catenin
Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.
T17256 Wnt pathway activator 1 Wnt/beta-catenin
Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM. Wnt pathway activator 1 is a potent Wnt activator for the treatment of androgenetic alopecia (AGA).
T77502 Wnt pathway inhibitor 3 Wnt/beta-catenin , Adenylyl cyclase
Wnt pathway inhibitor 3 is a potent AC1 inhibitor with an IC50 value of 45 nM.Wnt pathway inhibitor 3 has antiproliferative activity and can be used in studies to ameliorate osteoarthritis in a mouse model of experimenta...
T77716 Wnt pathway inhibitor 4 Antibacterial
Wnt pathway inhibitor 4 is a small molecule antimicrobial agent with antibacterial and antiproliferative activity against cancer cells.
T3156 Ciliobrevin A Hedgehog Pathway Inhibitor 4,HPI-4 Hedgehog/Smoothened
Ciliobrevin A (HPI-4) is an inhibitor of hedgehog signaling pathway with an IC50 <10 μM.
T38519 YB-0158 Wnt pathway inhibitor 2,YB-0158
YB-0158 (Wnt pathway inhibitor 2) is a powerful peptidomimetic compound that effectively targets colorectal cancer stem cells (CSCs) by disrupting the interaction between Sam68 and Src proteins. This compound acts as a r...
T25502 HIF-IN-33 HIF IN 33,HIF Pathway Inhibitor 33
HIF-IN-33 is an inhibitor of HIF pathway.
T12246 CB-103 Gamma-secretase
CB-103 is a orally active inhibitor of notch signaling pathway, with anti-tumor activity.
T9810 TNIK-IN-5 Wnt/beta-catenin
TNIK-IN-5 is an potent TNIK inhibitor (IC50= 0.05 μM). TNIK-IN-5 potently inhibits Wnt signaling in intact cells. TNIK-IN-5 exhibits excellent in vitro anti-colorectal cancer activity.
T12885 SGC-AAK1-1 AAK1 (AP2 associated kinase 1)
SGC-AAK1-1 is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) (IC50 of 270 nM and a Ki of 9 nM),and is a chemical probe.
T9165 AZD5305 PARP
AZD5305 is a potent, selective and oral active PARP inhibitor.
T5210 BAI1 Apoptosis , BCL
BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).
T19857 Glyphosate Atila,Lancer,Folusen Apoptosis , Autophagy
Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.
T41286 N6-Isopentenyladenosine Endogenous Metabolite , Autophagy
N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity. N6-Isopentenyladenosine, an RNA modification found in cytokinins, regulates plant growth/different...
T5486 RU.521 RU320521 DNA , cGAS
RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.
T5465 PF-5274857 PF-5274857 freebase Smo
PF-5274857 (PF-5274857 free base) is an effective and selective hedgehog signaling pathway inhibitor (IC50: 5.8 nM and a Ki: 4.6 nM). PF-5274857 is a potentially attractive clinical candidate for the treatment of tumor t...
T14327 AS1949490 Phosphatase
AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM.
T20723 LGE-899 Sonidegib metabolite M48,LGE 899 Drug Metabolite
LGE-899 (Sonidegib metabolite M48) is a main metabolite of Sonidegib which is an inhibitor of the hedgehog pathway. The Tmax of LGE-899(60 h) is much longer than Sonidegib.
T22665 PD 128042 CI 976 Acyltransferase
PD 128042 (CI 976) is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a potent lysophospholipid acyltransferase(LPAT) inhibitor. CI 976 inhibits Golgi-associated LPAT activity (IC50: 15 μM) and multi...
T7739 L-Leucyl-L-Leucine methyl ester hydrochloride Leu-Leu-ome hydrochloride Others , Endogenous Metabolite
L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) is a lysosomal condensation product that cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes.
T9189 Iptacopan hydrochloride Iptacopan HCl,LNP023 hydrochloride Complement System
Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity b...
T1967 AZD-3463 ALK/IGF1R inhibitor Apoptosis , IGF-1R , ALK , Autophagy
AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.
T1487 Fluvastatin sodium XU 62320 sodium,XU-62-320,Fluvastatin sodium salt Ferroptosis , HMG-CoA Reductase , Autophagy
Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent.
T9105 NF-κB-IN-1 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)- IκB/IKK , NF-κB
NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 dir...
T6146 Dorsomorphin dihydrochloride BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride AMPK , Autophagy , TGF-beta/Smad
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.
T8851 I3MT-3 HMPSNE Hippo pathway
I3MT-3 (HMPSNE) (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST...
T60055 Chromeceptin 2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile Akt , IGF-1R , mTOR
Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.
T24784 SF5 SF-5,SF 5 Apoptosis
SF5 is an inhibitor of the apoptosis pathway. Which is through the JNK-p53-caspase apoptotic cascade.
T67866 YW2036 Wnt/beta-catenin
YW2036 is an inhibitor of Wnt signaling pathway.
T20759 XRP44X XRP-44-X,XRP 44X,XRP-44X,XRP 44 X Ras
XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.
T4609 Exo1 Others
Exo1 is an inhibitor of the exocytic pathway
T3588 JK184 Hedgehog/Smoothened
JK184 is a potent Hedgehog (Hh) pathway inhibitor.
T1806 IDO-IN-7 NLG919,Navoximod,NLG-919 analogue,GDC-0919 Indoleamine 2,3-Dioxygenase (IDO)
IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.
T6165 Bardoxolone Methyl RTA 402,CDDO Methyl ester,TP-155,NSC 713200 Apoptosis , IκB/IKK , Ferroptosis , Nrf2 , Autophagy
Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-tumor and anti-inflammatory activities.
T64388 3-Phenoxybenzaldehyde Complement System
3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM.
T2273 ITD-1 TGF-beta/Smad
ITD-1 is a potent and highly selective TGFβ pathway inhibitor.
T24642 YH-306 YH306,TRV055 acetate (25849-90-5 Free base) MMP , MMP , FAK , Rho , PI3K , Src
YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.
T50107 Ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate Others
ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate is a synthetic compound belonging to the curcumin family. It is involved in the regulation of immune response and inflammation through ...
T60038 5-(5-methyl-1H-1,2,4-triazol-3-yl)-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole Others
5-(5-methyl-1H-1,2,4-triazol-3-yl)-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole can be used in the synthesis of heterocyclic compounds to inhibit HIF pathway activity.
T23861 CAY10526 CAY-10526,BTH,CAY 10526 Prostaglandin Receptor
CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.
T8917 PAR-2-IN-1 IUN76750 Protease-activated Receptor
PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.
T2651 IWR-1 IWR-1-endo,endo-IWR 1 Wnt/beta-catenin
IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).
T77780 Zamaporvint RXC004 Others
Zamaporvint (RXC004) is a selective, orally active and potent inhibitor of the Wnt pathway that acts on the membrane-bound fatty acyltransferase porcupine to block Wnt ligand palmitoylation, secretion, and pathway activa...
T0459 Sulindac Arthrocine,MK-231,Clinoril,Sulindac sulfoxide COX , Autophagy
Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cycl...
T37422L Ras Inhibitory Peptide acetate Ras Inhibitory Peptide acetate(159088-48-9 Free base) Ras
Ras Inhibitory Peptide acetate is a peptide involved in the Ras-dependent signaling pathway that plays an important role in human cancers initiated by oncogenic receptors.
T67884 β-catenin modulator IIa-661 Wnt/beta-catenin
β-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.
T3169 KC7F2 HIF/HIF Prolyl-Hydroxylase , HIF
KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.
T5642 Tegatrabetan BC2059 Wnt/beta-catenin
Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.
T5636 Adavivint Adavivint (SM04690) Wnt/beta-catenin
Adavivint (Adavivint (SM04690)) (SM04690) is a Wnt pathway inhibitor.
T38563 Raptinal Caspase
Raptinal activates caspase-3 directly and initiates intrinsic caspase-dependent apoptosis pathway in multiple cell lines.

Compounds

Wnt pathway activator 2
T13345
Synonym:
Target: Others, Wnt/beta-catenin
Wnt pathway activator 1
T17256
Synonym:
Target: Wnt/beta-catenin
Wnt pathway inhibitor 3
T77502
Synonym:
Target: Wnt/beta-catenin, Adenylyl cyclase
Wnt pathway inhibitor 4
T77716
Synonym:
Target: Antibacterial
Ciliobrevin A
T3156
Synonym: Hedgehog Pathway Inhibitor 4,HPI-4
Target: Hedgehog/Smoothened
YB-0158
T38519
Synonym: Wnt pathway inhibitor 2,YB-0158
Target:
HIF-IN-33
T25502
Synonym: HIF IN 33,HIF Pathway Inhibitor 33
Target:
CB-103
T12246
Synonym:
Target: Gamma-secretase
TNIK-IN-5
T9810
Synonym:
Target: Wnt/beta-catenin
SGC-AAK1-1
T12885
Synonym:
Target: AAK1 (AP2 associated kinase 1)
AZD5305
T9165
Synonym:
Target: PARP
BAI1
T5210
Synonym:
Target: Apoptosis, BCL
Glyphosate
T19857
Synonym: Atila,Lancer,Folusen
Target: Apoptosis, Autophagy
N6-Isopentenyladenosine
T41286
Synonym:
Target: Endogenous Metabolite, Autophagy
RU.521
T5486
Synonym: RU320521
Target: DNA, cGAS
PF-5274857
T5465
Synonym: PF-5274857 freebase
Target: Smo
AS1949490
T14327
Synonym:
Target: Phosphatase
LGE-899
T20723
Synonym: Sonidegib metabolite M48,LGE 899
Target: Drug Metabolite
PD 128042
T22665
Synonym: CI 976
Target: Acyltransferase
L-Leucyl-L-Leucine methyl ester hydrochloride
T7739
Synonym: Leu-Leu-ome hydrochloride
Target: Others, Endogenous Metabolite
Iptacopan hydrochloride
T9189
Synonym: Iptacopan HCl,LNP023 hydrochloride
Target: Complement System
AZD-3463
T1967
Synonym: ALK/IGF1R inhibitor
Target: Apoptosis, IGF-1R, ALK, Autophagy
Fluvastatin sodium
T1487
Synonym: XU 62320 sodium,XU-62-320,Fluvastatin sodium salt
Target: Ferroptosis, HMG-CoA Reductase, Autophagy
NF-κB-IN-1
T9105
Synonym: 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-
Target: IκB/IKK, NF-κB
Dorsomorphin dihydrochloride
T6146
Synonym: BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride
Target: AMPK, Autophagy, TGF-beta/Smad
I3MT-3
T8851
Synonym: HMPSNE
Target: Hippo pathway
Chromeceptin
T60055
Synonym: 2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile
Target: Akt, IGF-1R, mTOR
SF5
T24784
Synonym: SF-5,SF 5
Target: Apoptosis
YW2036
T67866
Synonym:
Target: Wnt/beta-catenin
XRP44X
T20759
Synonym: XRP-44-X,XRP 44X,XRP-44X,XRP 44 X
Target: Ras
Exo1
T4609
Synonym:
Target: Others
JK184
T3588
Synonym:
Target: Hedgehog/Smoothened
IDO-IN-7
T1806
Synonym: NLG919,Navoximod,NLG-919 analogue,GDC-0919
Target: Indoleamine 2,3-Dioxygenase (IDO)
Bardoxolone Methyl
T6165
Synonym: RTA 402,CDDO Methyl ester,TP-155,NSC 713200
Target: Apoptosis, IκB/IKK, Ferroptosis, Nrf2, Autophagy
3-Phenoxybenzaldehyde
T64388
Synonym:
Target: Complement System
ITD-1
T2273
Synonym:
Target: TGF-beta/Smad
YH-306
T24642
Synonym: YH306,TRV055 acetate (25849-90-5 Free base)
Target: MMP, MMP, FAK, Rho, PI3K, Src
ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate
T50107
Synonym:
Target: Others
5-(5-methyl-1H-1,2,4-triazol-3-yl)-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole
T60038
Synonym:
Target: Others
CAY10526
T23861
Synonym: CAY-10526,BTH,CAY 10526
Target: Prostaglandin Receptor
PAR-2-IN-1
T8917
Synonym: IUN76750
Target: Protease-activated Receptor
IWR-1
T2651
Synonym: IWR-1-endo,endo-IWR 1
Target: Wnt/beta-catenin
Zamaporvint
T77780
Synonym: RXC004
Target: Others
Sulindac
T0459
Synonym: Arthrocine,MK-231,Clinoril,Sulindac sulfoxide
Target: COX, Autophagy
Ras Inhibitory Peptide acetate
T37422L
Synonym: Ras Inhibitory Peptide acetate(159088-48-9 Free base)
Target: Ras
β-catenin modulator IIa-661
T67884
Synonym:
Target: Wnt/beta-catenin
KC7F2
T3169
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, HIF
Tegatrabetan
T5642
Synonym: BC2059
Target: Wnt/beta-catenin
Adavivint
T5636
Synonym: Adavivint (SM04690)
Target: Wnt/beta-catenin
Raptinal
T38563
Synonym:
Target: Caspase
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Cat No. Product Name Synonyms Targets
T4766 3-Methylglutaric acid Endogenous Metabolite
Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PMID 6181239 ). Methylglutaric acid is als...
T3912 Saikosaponin B1 Others
Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro.
TN1019 Beta-mangostin β-Mangostin Apoptosis , Antibacterial , Parasite
Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculo...
TN6339 (R)-5-Hydroxy-1,7-diphenylheptan-3-one (5R)-Dihydroyashabushiketol Others
(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) is extracted from the rhizomes of Alpinia officinarum, a Chinese medicinal herb. (R)-5-Hydroxy-1,7-diphenylheptan-3-one inhibits melanogenesis in theop...
TN6714 Geranylgeraniol FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095 Apoptosis
Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) ...
TN6739 Angoline 6-Methoxyldihydrochelerythrine IL Receptor , STAT
Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits can...
TQ0190 D-Xylulose Others , Endogenous Metabolite
D-Xylulose is converted from xylitol by the enzyme NAD+-linked xylitol dehydrogenase in the glucuronate pathway, the most important xylitol-handling metabolic pathway in mammals.
T4941 D-Fructose-6-phosphate disodium salt D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT Others , Endogenous Metabolite
D-Fructose-6-phosphate disodium salt (D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT) is an important intermediate in the Carbohydrates pathway. The interconversion of glucose-6-phosphate and fructose-6-phosphate, the second step ...
T5253 3-Methyladipic acid Others , Endogenous Metabolite
3-Methyladipic acid is a metabolite of the catabolism of phytanic acid. Patients with adult Refsums disease (ARD) are unable to detoxify phytanic acid by alpha-oxidation, and so the w-oxidation pathway is the only metabo...
T4901 5'-Guanylic acid disodium salt Guanosine 5'-monophosphate disodium salt,GMP-5 Others , Endogenous Metabolite
5'-Guanylic acid disodium salt (GMP-5) belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthy...
T8281 (R)-Sulforaphane L-Sulforaphane Nrf2
(R)-Sulforaphane (L-Sulforaphane) is a potent inducer of the Keap1/Nrf2/ARE pathway.
TJS1779 Protosappanin A PTA NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory ...
TN2237 Steviol-19-O-glucoside Steviol-19-O-Glucoside Others
Steviol-19-O-glucoside is a natural product from the steviol glycosides biosynthesis pathway in Stevia rebuadiana.
T19343L Glycerol 3-phosphate biscyclohexylammonium salt Endogenous Metabolite
Glycerol 3-phosphate biscyclohexylammonium salt is an endogenous metabolite produced by cytosolic glycerol 3-phosphate dehydrogenase pathway.
T3S1227 Aristolactam I Aristolactam,Aristololactam I,Aristololactum Apoptosis , Caspase
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF...
TN1271 Scutellarein tetramethyl ether 4',5,6,7-Tetramethoxyflavone PAFR
Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is extracted from Siam weeds and exhibits anti-inflammatory activity through NF-κB pathway.
T19343 Sn-Glycerol 3-phosphate Glycerol 3-phosphate,sn-Glycerol 3-phosphate lithium salt Endogenous Metabolite
sn-Glycerol 3-phosphate is produced by the reduction of dihydroxyacetone phosphate by NADH formed during glycolysis of the cytoplasmic glycerol 3-phosphate dehydrogenase pathway.
T2O2776 L-Valine Others , Endogenous Metabolite
A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
T8092 Taurohyodeoxycholic acid sodium salt Sodium taurohyodeoxycholate hydrate Caspase
Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation.
T8200 Ginkgolide K AMPK , Autophagy
Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.
T3386 Kaempferitrin Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside cell cycle arrest , Glucokinase , IGF-1R
Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucos...
T20255 L-Galactose Galactose, L- Endogenous Metabolite
L-Galactose (Galactose, L-) is a natural product that is widely found in plants and animals. L-Galactose has been shown to be a key intermediate in the molecular pathway for the conversion of D-glucose to oxalic acid in ...
TN1786 Isomerazin Isomeranzin ERK , NF-κB , AChE
Isomerazin (Isomeranzin) has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway.
T2995 Chrysophanol 3-Methylchrysazin,Chrysophanic Acid,Turkey Rhubarb EGFR
Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel.
TN1836 Kudinoside D LDL , AMPK , PPAR
Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway.
T4S0290 Araloside A Chikusetsusaponin IV RAAS , Fas/FasL
Araloside A (Chikusetsusaponin IV) might relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway.
TN1058 Pelargonidin chloride NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway.
T7468 (-​)​-​α-​Terpineol α-Terpineol Others
(-)-α-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway
T6S1367 Procyanidin B2 Proanthocyanidin B2 Reactive Oxygen Species , NOD
Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression ...
T2845 Imperatorin Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen TRP/TRPV Channel , AChR , AChE , NOD
Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
T5793 Britannin Apoptosis , AMPK , Autophagy
Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.
T7210 Guanosine 5'-diphosphate GDP Endogenous Metabolite
Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.
T6S0107 Peimine Wanpeinine A,Dihydroisoimperialine,Verticine Others
1. Peimine (Wanpeinine A) has good anti-inflammatory effects in vivo. 2. Peimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB signaling pathway.
TN1684 Ginsenoside F5 Apoptosis
Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway
TN6771 Malabaricone B Others
Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.
TN2232 Soyasaponin Ab NOS , NF-κB , COX
Soyasaponin Ab may represent a viable candidate for effective vaccine adjuvant, TLR4 receptor dependent pathway may be involved in immune stimulatory effects of soyasaponin Ab.
T40646 Lipoteichoic acid Complement System
Lipoteichoic acid, a polymer of Staphylococcus aureus cell wall, activates the complement system by inducing C3 and inhibiting CD55, and reduces fat deposition via the IGF-1 pathway.
TN1833 Karacoline NF-κB
Karacolinem is a natural product, reduces degradation of the extracellular matrix (ECM) in intervertebral disc degeneration (IDD) via the NF-κB signaling pathway.
T4672 Brevilin A Apoptosis , Anti-infection , JAK , STAT , Autophagy
Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT si...
T5258 Dodecanedioic acid diammonium salt 1,10-Decanedicarboxylic acid diammonium salt Others
Dodecanedioic acid diammonium salt (1,10-Decanedicarboxylic acid diammonium salt) is a dicarboxylic acid which is water-soluble and involves in a metabolic pathway intermediate to those of lipids and carbohydrates.
TN1077 Taraxerol Skimmiol,Alnulin Apoptosis , NF-κB
Taraxerol(Alnulin) is an anti-inflammatory and anticancer compound derived from dandelion.Taraxerol reduces acute inflammation and induces apoptosis by inhibiting the NF-κB signaling pathway.
T6S1880 Benzoylaconine Pikraconitin,Isaconitine,Benzoylaconitine Others
Benzoylaconine (Isaconitine) is an alkaloid in the Chinese traditional medicine Radix Aconiti Lateralis Preparata (Fuzi). Benzoylaconine and aconitine can induce reproductive toxicity in BeWo Cell, the amino acid metabol...
T4898 Potassium 1-carboxyvinyl hydrogenphosphate PEP-K,Phospho(enol)pyruvic acid monopotassium Others , Endogenous Metabolite
Potassium 1-carboxyvinyl hydrogenphosphate (PEP-K) is involved in glycolysis and gluconeogeneis. In glycolysis, PEP is metabolized by Pyruvate Kinase to yield pyruvate. In plants, PEP is involved in the formation of arom...
T13803 N-Oleoyl glycine Cannabinoid Receptor , Akt , Endogenous Metabolite , PPAR
N-Oleoyl Glycine, a Lipoamino Acid, Stimulates Adipogenesis Associated With Activation of CB1 Receptor and Akt Signaling Pathway in 3T3-L1 Adipocyte
T3871 Daucosterol Alexandrin,Sitogluside,β-Sitosterol β-D-glucoside,Eleutheroside A Glucosidase
Daucosterol (Sitogluside) has proliferation-enhancing activity, may be involved in the IGF1-AKT pathway. Daucosterol(β-Sitosterol β-D-glucoside) has efficient and inexpensive neuroprotectant effect, to contribute to IGF1...
T2140 Parthenolide (-)-Parthenolide Apoptosis , Mitophagy , NF-κB , HDAC , Autophagy
(-)-Parthenolide ((-)-Parthenolide), an inhibitor of the Nuclear Factor-κB Pathway, also promotes the ubiquitination of MDM2 and activates p53 cellular functions.
T5S0331 Isoliquiritin Neoisoliquritin p53 , Antifungal
1. Isoliquiritin (Neoisoliquritin) has antitussive effects. 2. Isoliquiritin has antidepressant-like effects. 3. Isoliquiritin, liquiritin and isoliquirigenin inhibits the p53-dependent pathway and shows crosstalk betwee...
T4096 Quinolinic acid pyridine-2,3-dicarboxylic acid,QUIN Endogenous Metabolite , NMDAR , iGluR
Quinolinic acid (QUIN) is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.
T2896 Alantolactone helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor Apoptosis , STAT , TGF-beta/Smad
Alantolactone (Inula camphor)(Alant camphor), a sesquiterpene lactone, has potential activity against triple-negative breast Y MDA-MB-231 cells by suppressing the signal transducer and activator of transcription 3 (STAT3...
T2739 Shikimic Acid Shikimate Others , Endogenous Metabolite
Shikimic Acid (Shikimate) is a tri-hydroxy cyclohexene carboxylic acid important in the biosynthesis of so many compounds that the shikimate pathway is named after it.
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Natural Products

3-Methylglutaric acid
T4766
Synonym:
Target: Endogenous Metabolite
Saikosaponin B1
T3912
Synonym:
Target: Others
Beta-mangostin
TN1019
Synonym: β-Mangostin
Target: Apoptosis, Antibacterial, Parasite
(R)-5-Hydroxy-1,7-diphenylheptan-3-one
TN6339
Synonym: (5R)-Dihydroyashabushiketol
Target: Others
Geranylgeraniol
TN6714
Synonym: FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095
Target: Apoptosis
Angoline
TN6739
Synonym: 6-Methoxyldihydrochelerythrine
Target: IL Receptor, STAT
D-Xylulose
TQ0190
Synonym:
Target: Others, Endogenous Metabolite
D-Fructose-6-phosphate disodium salt
T4941
Synonym: D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT
Target: Others, Endogenous Metabolite
3-Methyladipic acid
T5253
Synonym:
Target: Others, Endogenous Metabolite
5'-Guanylic acid disodium salt
T4901
Synonym: Guanosine 5'-monophosphate disodium salt,GMP-5
Target: Others, Endogenous Metabolite
(R)-Sulforaphane
T8281
Synonym: L-Sulforaphane
Target: Nrf2
Protosappanin A
TJS1779
Synonym: PTA
Target: NADPH-oxidase, IL Receptor, IκB/IKK, TNF, NF-κB, TLR, ROS, COX, HIV Protease, JAK, NO Synthase, STAT
Steviol-19-O-glucoside
TN2237
Synonym: Steviol-19-O-Glucoside
Target: Others
Glycerol 3-phosphate biscyclohexylammonium salt
T19343L
Synonym:
Target: Endogenous Metabolite
Aristolactam I
T3S1227
Synonym: Aristolactam,Aristololactam I,Aristololactum
Target: Apoptosis, Caspase
Scutellarein tetramethyl ether
TN1271
Synonym: 4',5,6,7-Tetramethoxyflavone
Target: PAFR
sn-Glycerol 3-phosphate
T19343
Synonym: Glycerol 3-phosphate,sn-Glycerol 3-phosphate lithium salt
Target: Endogenous Metabolite
L-Valine
T2O2776
Synonym:
Target: Others, Endogenous Metabolite
Taurohyodeoxycholic acid sodium salt
T8092
Synonym: Sodium taurohyodeoxycholate hydrate
Target: Caspase
Ginkgolide K
T8200
Synonym:
Target: AMPK, Autophagy
Kaempferitrin
T3386
Synonym: Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside
Target: cell cycle arrest, Glucokinase, IGF-1R
L-Galactose
T20255
Synonym: Galactose, L-
Target: Endogenous Metabolite
Isomerazin
TN1786
Synonym: Isomeranzin
Target: ERK, NF-κB, AChE
Chrysophanol
T2995
Synonym: 3-Methylchrysazin,Chrysophanic Acid,Turkey Rhubarb
Target: EGFR
Kudinoside D
TN1836
Synonym:
Target: LDL, AMPK, PPAR
Araloside A
T4S0290
Synonym: Chikusetsusaponin IV
Target: RAAS, Fas/FasL
Pelargonidin chloride
TN1058
Synonym:
Target: NOS, Reactive Oxygen Species, Nrf2, NO Synthase
(-​)​-​α-​Terpineol
T7468
Synonym: α-Terpineol
Target: Others
Procyanidin B2
T6S1367
Synonym: Proanthocyanidin B2
Target: Reactive Oxygen Species, NOD
Imperatorin
T2845
Synonym: Ammidin,8-Isoamylenoxypsoralen,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen
Target: TRP/TRPV Channel, AChR, AChE, NOD
Britannin
T5793
Synonym:
Target: Apoptosis, AMPK, Autophagy
Guanosine 5'-diphosphate
T7210
Synonym: GDP
Target: Endogenous Metabolite
Peimine
T6S0107
Synonym: Wanpeinine A,Dihydroisoimperialine,Verticine
Target: Others
Ginsenoside F5
TN1684
Synonym:
Target: Apoptosis
Malabaricone B
TN6771
Synonym:
Target: Others
Soyasaponin Ab
TN2232
Synonym:
Target: NOS, NF-κB, COX
Lipoteichoic acid
T40646
Synonym:
Target: Complement System
Karacoline
TN1833
Synonym:
Target: NF-κB
Brevilin A
T4672
Synonym:
Target: Apoptosis, Anti-infection, JAK, STAT, Autophagy
Dodecanedioic acid diammonium salt
T5258
Synonym: 1,10-Decanedicarboxylic acid diammonium salt
Target: Others
Taraxerol
TN1077
Synonym: Skimmiol,Alnulin
Target: Apoptosis, NF-κB
Benzoylaconine
T6S1880
Synonym: Pikraconitin,Isaconitine,Benzoylaconitine
Target: Others
Potassium 1-carboxyvinyl hydrogenphosphate
T4898
Synonym: PEP-K,Phospho(enol)pyruvic acid monopotassium
Target: Others, Endogenous Metabolite
N-Oleoyl glycine
T13803
Synonym:
Target: Cannabinoid Receptor, Akt, Endogenous Metabolite, PPAR
Daucosterol
T3871
Synonym: Alexandrin,Sitogluside,β-Sitosterol β-D-glucoside,Eleutheroside A
Target: Glucosidase
Parthenolide
T2140
Synonym: (-)-Parthenolide
Target: Apoptosis, Mitophagy, NF-κB, HDAC, Autophagy
Isoliquiritin
T5S0331
Synonym: Neoisoliquritin
Target: p53, Antifungal
Quinolinic acid
T4096
Synonym: pyridine-2,3-dicarboxylic acid,QUIN
Target: Endogenous Metabolite, NMDAR, iGluR
Alantolactone
T2896
Synonym: helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,Inula camphor
Target: Apoptosis, STAT, TGF-beta/Smad
Shikimic Acid
T2739
Synonym: Shikimate
Target: Others, Endogenous Metabolite
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Recombinant Proteins

Species：
Human (618)
Mouse (236)
Rat (55)
Cynomolgus (39)
Rhesus (19)
Canine (16)
E. coli (9)
Bovine (5)
H1N1 (5)
H3N2 (4)
Expression System：
HEK293 (517)
E. coli (335)
Baculovirus-Insect Cells (90)
Human Cells (59)
Baculovirus (29)
Yeast (23)
in vitro E. coli expression system (9)
CHO (5)
Tag：
His (325)
hFc (131)
N-terminal 6xHis-tagged (87)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (64)
Tag Free (63)
C-6His (43)
His,GST (34)
N-terminal 6xHis-SUMO-tagged (32)
C-His (31)
N-6His (23)
Cat No. Product Name Species Expression System
TMPY-01174 DKK1 Protein, Rhesus, Recombinant (N256Q, His) Rhesus HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-04811 DKK1 Protein, Mouse, Recombinant (His) Mouse HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-01121 DKK3 Protein, Mouse, Recombinant (His) Mouse HEK293
DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 p...
TMPY-00775 DKK1 Protein, Human, Recombinant (His) Human HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-01030 TFPI Protein, Human, Recombinant (His) Human HEK293
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit...
TMPY-01175 DKK1 Protein, Rhesus, Recombinant (N256Q, mFc) Rhesus HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-05797 DKK1 Protein, Rat, Recombinant (His) Rat HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-06377 DKK3 Protein, Human, Recombinant Human HEK293
DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 p...
TMPY-02859 TFPI2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotei...
TMPY-05479 DKK1 Protein, Human, Recombinant (hFc) Human HEK293
Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 ...
TMPY-00950 WISP1/CCN4 Protein, Human, Recombinant (His) Human HEK293
CCN4/Wnt-induced secreted protein 1 (WISP1) is a secreted, cysteine-rich, heparin-binding glycoprotein, belonging to the CCN (CTGF/CYR61/NOV) family of growth factors, and is involved in diverse biological functions such...
TMPY-02329 TFPI2 Protein, Mouse, Recombinant (His) Mouse HEK293
Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotei...
TMPY-01004 TFPI2 Protein, Human, Recombinant (His) Human HEK293
Tissue factor pathway inhibitor-2 (TFPI2), a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). It is a 32 kDa matrix-associated glycoprotei...
TMPY-05179 TFPI Protein, Human, Recombinant (His), Biotinylated Human HEK293
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit...
TMPY-00928 TFPI Protein, Mouse, Recombinant (His) Mouse HEK293
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit...
TMPY-03626 R-Spondin 1/RSPO1 Protein, Human, Recombinant Human CHO
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r...
TMPY-01147 R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) Human HEK293
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r...
TMPY-03197 R-Spondin 1/RSPO1 Protein, Mouse, Recombinant (His) Mouse CHO
RSPO1 gene is a member of the R-spondin family. It encodes RSPO1 which is known as a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, RSPO1 induces the r...
TMPY-05081 Notch 1 Protein, Human, Recombinant (hFc) Human HEK293
NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair...
TMPY-00680 BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) Human,Mouse,Rat,Rhesus,Canine HEK293
BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-06418 R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) Human HEK293
R-spondin-2, also known as RSPO2, synergizes with Wnt to activate beta-catenin. RSPO2 is secreted proteins that regulate beta-catenin signaling. Activator of the beta-catenin signaling cascade leads to TCF-dependent gene...
TMPY-01429 RELT/TNFRSF19L Protein, Human, Recombinant (His) Human HEK293
Receptor expressed in lymphoid tissues (RELT), also known as tumor necrosis factor receptor superfamily, member 19-like (TNFRSF19L), is a member of the TNF-receptor superfamily. This receptor is especially abundant in he...
TMPY-02028 RON/CD136 Protein, Human, Recombinant (His) Human HEK293
The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. ...
TMPY-04874 IL-23 P19/IL23A Protein, Human, Recombinant (hFc) Human HEK293
IL-23, which is mainly secreted by antigen-presenting cells, is a member of the IL-12 family, which includes IL-12, IL-27, and IL-35. IL-23 is a heterodimeric cytokine, comprised of a unique p19 subunit and p4 subunit, t...
TMPY-02879 IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158) Human E. coli
Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine that plays an important role in innate and adaptive immunity. IL-1F6 activates MAPK and NF-kB pathways a...
TMPY-04153 RNF43 Protein, Human, Recombinant (His) Human HEK293
RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr...
TMPY-00686 Complement C2 Protein, Human, Recombinant (His) Human HEK293
Complement component C2 is part of the classical complement pathway which plays a major role in innate immunity against infection. C2 is a glycoprotein synthesized in liver hepatocytes and several other cell types in ext...
TMPY-02481 ACOX1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, ...
TMPY-01081 SR-BI/SCARB1 Protein, Human, Recombinant (His) Human HEK293
Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPY-01101 Coagulation factor X/F10 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the...
TMPY-05435 ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) Human HEK293
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-04830 GAS6 Protein, Mouse, Recombinant (His) Mouse HEK293
The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPY-05242 CRLF2/TSLPR Protein, Human, Recombinant (His) Human HEK293
Overexpression of cytokine receptor-like factor 2 (CRLF2) due to chromosomal rearrangement has been observed in acute lymphoblastic leukemia (ALL) and reported to contribute to oncogenesis and unfavorable outcome in ALL....
TMPY-02473 ICOS Protein, Mouse, Recombinant (hFc) Mouse HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPY-05156 ICOS Protein, Human, Recombinant (rFc) Human HEK293
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ...
TMPY-02279 Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His) Human E. coli
Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key en...
TMPY-03565 Mannan Binding Lectin/MBL2 Protein, Human, Recombinant Human CHO
MBL (mannose-binding lectin) is primarily a liver-derived collagen-like serum protein, which binds sugar structures on micro-organisms and dying host cells and is one of the four known mediators that initiate activation ...
TMPY-00392 PAM Protein, Human, Recombinant (His) Human HEK293
Peptidylglycine alpha-amidating monooxygenase (PAM) is highly expressed in neurons and endocrine cells, where it catalyzes one of the final steps in the biosynthesis of bioactive peptides. PAM is also expressed in unicel...
TMPY-01750 HVEM Protein, Human, Recombinant (His) Human HEK293
Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup...
TMPY-01084 TrkA Protein, Human, Recombinant (His) Human HEK293
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPY-02361 VEGFR2/KDR Protein, Human, Recombinant (His) Human HEK293
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-01725 Leptin Receptor Protein, Human, Recombinant (His) Human HEK293
Leptin Receptor or CD295 belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-spe...
TMPY-01281 ACVR2B Protein, Mouse, Recombinant (His) Mouse HEK293
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPY-00949 VEGFR3/FLT4 Protein, Human, Recombinant (His) Human HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-02333 ULBP-2 Protein, Human, Recombinant (His) Human HEK293
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPY-06842 BMP-4 Protein, Human, Recombinant (E399D) Human E. coli
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His) Mouse HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-00654 ACVR2B Protein, Human, Recombinant (hFc) Human HEK293
ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of ...
TMPY-05592 ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated Human HEK293
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e...
TMPY-02676 EGFR Protein, Mouse, Recombinant (His) Mouse HEK293
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
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DKK1 Protein, Rhesus, Recombinant (N256Q, His)
TMPY-01174
Species: Rhesus
Expression System: HEK293
DKK1 Protein, Mouse, Recombinant (His)
TMPY-04811
Species: Mouse
Expression System: HEK293
DKK3 Protein, Mouse, Recombinant (His)
TMPY-01121
Species: Mouse
Expression System: HEK293
DKK1 Protein, Human, Recombinant (His)
TMPY-00775
Species: Human
Expression System: HEK293
TFPI Protein, Human, Recombinant (His)
TMPY-01030
Species: Human
Expression System: HEK293
DKK1 Protein, Rhesus, Recombinant (N256Q, mFc)
TMPY-01175
Species: Rhesus
Expression System: HEK293
DKK1 Protein, Rat, Recombinant (His)
TMPY-05797
Species: Rat
Expression System: HEK293
DKK3 Protein, Human, Recombinant
TMPY-06377
Species: Human
Expression System: HEK293
TFPI2 Protein, Mouse, Recombinant (hFc)
TMPY-02859
Species: Mouse
Expression System: HEK293
DKK1 Protein, Human, Recombinant (hFc)
TMPY-05479
Species: Human
Expression System: HEK293
WISP1/CCN4 Protein, Human, Recombinant (His)
TMPY-00950
Species: Human
Expression System: HEK293
TFPI2 Protein, Mouse, Recombinant (His)
TMPY-02329
Species: Mouse
Expression System: HEK293
TFPI2 Protein, Human, Recombinant (His)
TMPY-01004
Species: Human
Expression System: HEK293
TFPI Protein, Human, Recombinant (His), Biotinylated
TMPY-05179
Species: Human
Expression System: HEK293
TFPI Protein, Mouse, Recombinant (His)
TMPY-00928
Species: Mouse
Expression System: HEK293
R-Spondin 1/RSPO1 Protein, Human, Recombinant
TMPY-03626
Species: Human
Expression System: CHO
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
TMPY-01147
Species: Human
Expression System: HEK293
R-Spondin 1/RSPO1 Protein, Mouse, Recombinant (His)
TMPY-03197
Species: Mouse
Expression System: CHO
Notch 1 Protein, Human, Recombinant (hFc)
TMPY-05081
Species: Human
Expression System: HEK293
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)
TMPY-00680
Species: Human,Mouse,Rat,Rhesus,Canine
Expression System: HEK293
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
TMPY-06418
Species: Human
Expression System: HEK293
RELT/TNFRSF19L Protein, Human, Recombinant (His)
TMPY-01429
Species: Human
Expression System: HEK293
RON/CD136 Protein, Human, Recombinant (His)
TMPY-02028
Species: Human
Expression System: HEK293
IL-23 P19/IL23A Protein, Human, Recombinant (hFc)
TMPY-04874
Species: Human
Expression System: HEK293
IL-36 alpha/IL-1F6 Protein, Human, Recombinant (aa 6-158)
TMPY-02879
Species: Human
Expression System: E. coli
RNF43 Protein, Human, Recombinant (His)
TMPY-04153
Species: Human
Expression System: HEK293
Complement C2 Protein, Human, Recombinant (His)
TMPY-00686
Species: Human
Expression System: HEK293
ACOX1 Protein, Human, Recombinant (His)
TMPY-02481
Species: Human
Expression System: Baculovirus-Insect Cells
SR-BI/SCARB1 Protein, Human, Recombinant (His)
TMPY-01081
Species: Human
Expression System: HEK293
Coagulation factor X/F10 Protein, Human, Recombinant (His)
TMPY-01101
Species: Human
Expression System: Baculovirus-Insect Cells
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
TMPY-05435
Species: Human
Expression System: HEK293
GAS6 Protein, Mouse, Recombinant (His)
TMPY-04830
Species: Mouse
Expression System: HEK293
CRLF2/TSLPR Protein, Human, Recombinant (His)
TMPY-05242
Species: Human
Expression System: HEK293
ICOS Protein, Mouse, Recombinant (hFc)
TMPY-02473
Species: Mouse
Expression System: HEK293
ICOS Protein, Human, Recombinant (rFc)
TMPY-05156
Species: Human
Expression System: HEK293
Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His)
TMPY-02279
Species: Human
Expression System: E. coli
Mannan Binding Lectin/MBL2 Protein, Human, Recombinant
TMPY-03565
Species: Human
Expression System: CHO
PAM Protein, Human, Recombinant (His)
TMPY-00392
Species: Human
Expression System: HEK293
HVEM Protein, Human, Recombinant (His)
TMPY-01750
Species: Human
Expression System: HEK293
TrkA Protein, Human, Recombinant (His)
TMPY-01084
Species: Human
Expression System: HEK293
VEGFR2/KDR Protein, Human, Recombinant (His)
TMPY-02361
Species: Human
Expression System: HEK293
Leptin Receptor Protein, Human, Recombinant (His)
TMPY-01725
Species: Human
Expression System: HEK293
ACVR2B Protein, Mouse, Recombinant (His)
TMPY-01281
Species: Mouse
Expression System: HEK293
VEGFR3/FLT4 Protein, Human, Recombinant (His)
TMPY-00949
Species: Human
Expression System: HEK293
ULBP-2 Protein, Human, Recombinant (His)
TMPY-02333
Species: Human
Expression System: HEK293
BMP-4 Protein, Human, Recombinant (E399D)
TMPY-06842
Species: Human
Expression System: E. coli
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
TMPY-01936
Species: Mouse
Expression System: HEK293
ACVR2B Protein, Human, Recombinant (hFc)
TMPY-00654
Species: Human
Expression System: HEK293
ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated
TMPY-05592
Species: Human
Expression System: HEK293
EGFR Protein, Mouse, Recombinant (His)
TMPY-02676
Species: Mouse
Expression System: HEK293
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Cat No. Product Name
L8500 HIF-1 Signaling Pathway Compound Library

1352 compounds
A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；
L1310 Cytoskeletal Signaling Pathway Compound Library

773 compounds
A unique collection of 773 cytoskeleton-related compounds, can be used for HTS and HCS；
L4300 Wnt/Hedgehog/Notch Compound Library

240 compounds
A unique collection of 240 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
L2521 Glycolysis Compound Library

560 compounds
560 glycolysis-related active compounds for high-throughput and high-content screening.
L1300 PI3K-AKT-mTOR Compound Library

425 compounds
A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;
L2010 Highly Selective Inhibitor Library

580 compounds
A collection of xunm highly selective inhibitors
L3700 JAK-STAT Compound Library

256 compounds
A unique collection of 256 JAK/STAT signaling targeted compounds for high throughput and high content screening;
L8720 Pyroptosis Compound Library

1077 compounds
1077 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.
L8700 Ferroptosis Compound Library

800 compounds
A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；
L2193 Anti-Liver Cancer Compound Library

1816 compounds
1816 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies.
L4020 NO PAINS Compound Library

9555 compounds
TargetMol created the L4020 NO-PAINS Compound Library that applied the PAINS filter, remaining 9555 small molecules that are suitable for new drug development, signaling pathway research, drug repurposing and other resea...
L1580 GPCR Compound Library Plus

338 compounds
Well-chosen 338 GPCR targeting compounds with unique structures;
L8600 Ubiquitination Compound Library

214 compounds
A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening；
L1120 AMPK-Targeted Compound Library

80 compounds
80 well-chosen unique AMPK-targeted small molecules；
L6750 PBCRBS Traditional Chinese Medicine Compound Library

588 compounds
A unique collection of 588 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis.
L2191 Anti-Breast Cancer Compound Library

1965 compounds
A unique collection of 1965 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study；
L2560 Metabolism Compound Library

2350 compounds
A unique collection of 2350 metabolic pathway-related bioactive small molecule compounds for high-throughput, high-content screening.
L2550 Glutamine Metabolism Compound Library

580 compounds
A unique collection of 580 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ...
L2510 Lipid Metabolism Compound Library

496 compounds
A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
L9700 Endoplasmic Reticulum Stress Compound Library

193 compounds
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
L8300 Chromatin Modification Compound Library

256 compounds
A unique collection of 256 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS);
L8110 Reprogramming Compound Library

1840 compounds
A unique collection of 1840 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening.

Libraries

HIF-1 Signaling Pathway Compound Library
L8500
Compounds: 1352
Cytoskeletal Signaling Pathway Compound Library
L1310
Compounds: 773
Wnt/Hedgehog/Notch Compound Library
L4300
Compounds: 240
Glycolysis Compound Library
L2521
Compounds: 560
PI3K-AKT-mTOR Compound Library
L1300
Compounds: 425
Highly Selective Inhibitor Library
L2010
Compounds: 580
JAK-STAT Compound Library
L3700
Compounds: 256
Pyroptosis Compound Library
L8720
Compounds: 1077
Ferroptosis Compound Library
L8700
Compounds: 800
Anti-Liver Cancer Compound Library
L2193
Compounds: 1816
NO PAINS Compound Library
L4020
Compounds: 9555
GPCR Compound Library Plus
L1580
Compounds: 338
Ubiquitination Compound Library
L8600
Compounds: 214
AMPK-Targeted Compound Library
L1120
Compounds: 80
PBCRBS Traditional Chinese Medicine Compound Library
L6750
Compounds: 588
Anti-Breast Cancer Compound Library
L2191
Compounds: 1965
Metabolism Compound Library
L2560
Compounds: 2350
Glutamine Metabolism Compound Library
L2550
Compounds: 580
Lipid Metabolism Compound Library
L2510
Compounds: 496
Endoplasmic Reticulum Stress Compound Library
L9700
Compounds: 193
Chromatin Modification Compound Library
L8300
Compounds: 256
Reprogramming Compound Library
L8110
Compounds: 1840
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