Home Tools
Log in
Products Inhibitors Libraries Recombinant Proteins Kits Services Contact Us
Cart
Peptides Monoclonal Antibodies Dye Reagents PROTAC Virtual Screening TargetMol Kits Cell Counting Kit-8 (CCK-8) Inhibitor Cocktails Natural Products Phenols Alkaloids Flavonoids
Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library
TargetMol
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Search Result

Search Results for " parkinson "

Targets

Others Transferase

38

Compounds

6

Natural Products

3

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T7831 Nitecapone Others , Transferase
Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)
T7626 Budipine Others
Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist,is an antiparkinsonian agent.
T9346 CVN424 GPR
CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.
T8849 PF-9601N MAO
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.
T9694 Emraclidine CVL-231 AChR
Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies.
T8975 PSB-SB-487 Cannabinoid Receptor
PSB-SB-487 is antagonist of GPR55.
T9228 Propionylpromazine hydrochloride Propiopromazine hydrochloride Dopamine Receptor
Propionylpromazine hydrochloride (Propiopromazine hydrochloride) is a dopamine receptor D2 (DRD2) antagonist.
T8869 B355252 Others
B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.
T22103 ML-193 CID 1261822 Cannabinoid Receptor
ML-193 (CID 1261822) is a potent and selective GPR55 antagonist( IC50 : 221 nM). It shows more than 27-fold selectivity for GPR55 over GPR35, CB1 and CB2, and can improve the motor and the sensorimotor deficits of Parkin...
T37792 A2A receptor antagonist 1 CPI-444 analog,A2A receptor antagonist 1 Adenosine Receptor
A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively.
T14782 Brilaroxazine RP5063 Dopamine Receptor , 5-HT Receptor
Brilaroxazine (RP5063) is a potent multimodal dopamine/5-HT modulator. Brilaroxazine is a partial agonist of dopamine D2, D3, and D4 receptors, 5-HT1A (Ki =1.5 nM) and 5-HT2A (Ki = 2.5 nM), and has antagonist activity 5-...
T0920 Ambroxol Ambroxolum,NA-872 P450 , Autophagy
Ambroxol (NA-872) is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a muco...
T6234 Ambroxol hydrochloride Mucosolvan,Mucoangin,Ambroxol HCl Sodium Channel , Autophagy
Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
T7002 Trihexyphenidyl hydrochloride Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride AChR
Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is an antiparkinsonian agent of the antimuscarinic class.
T5678 Lazabemide hydrochloride N-(2-Aminoethyl)-5-chlor-2-pyridincarbox MAO , Monoamine Oxidase
Lazabemide hydrochloride (N-(2-Aminoethyl)-5-chlor-2-pyridincarbox) is a reversible and selective mao-b inhibitor(Ki：7.9nM).
T24047 Etilevodopa hydrochloride Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester Others , Dopamine Receptor , Drug Metabolite
Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.
T9409 Mesdopetam hemitartrate IRL790 hemitartrate,1-​Propanamine, N-​[2-​[3-​fluoro-​5-​(methylsulfonyl)​phenoxy]​ethyl]​-​, (2R,​3R)​-​2,​3-​dihydroxybutanedioat​e (2:1) Dopamine Receptor
Mesdopetam hemitartrate (IRL790 hemitartrate) is an antagonist of dopamine D3 receptor (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor). It has psychomotor stabilizing properties.
T5470 LAZABEMIDE Ro 19-6327 MAO , Monoamine Oxidase
Lazabemide (Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively).
T6651 Safinamide mesylate PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate MAO , Monoamine Oxidase
Safinamide mesylate (EMD 1195686 mesylate) , a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.
T12525 Pozanicline dihydrochloride ABT-089 dihydrochloride AChR
Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of nicotinic acetylcholine receptor (nAChR) (Ki = 16.7 nM)
T1751 Eliprodil SL-820715 NMDAR , iGluR
Eliprodil (SL-820715)(SL-820715), a non-competitive NR2B-NMDA receptor antagonist(IC50: 1 uM), less effective for NR2A- and NR2C-containing receptors(IC50> 100 uM). It has been used in trials studying the treatment of Pa...
T1628 Rivastigmine tartrate SDZ-ENA 713,ENA 713 AChR , AChE
Rivastigmine tartrate (SDZ-ENA 713) is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON...
T7746 Eltoprazine dihydrochloride Others
Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson´s disease (PD) and in dyskinetic PD pati...
T1406 Amantadine hydrochloride 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride Dopamine Receptor , Influenza Virus
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.
T2076 Pimavanserin ACP-103 5-HT Receptor
Pimavanserin (ACP-103)(ACP-103) is an effective and specific 5-HT2A receptor inverse agonist (mean pIC50: 8.7, in the cell-based functional assay). Pimavanserin is an atypical antipsychotic used in the treatment of hallu...
T2226 Pergolide mesylate Pergolide mesylate salt,LY127809,Pergolide methanesulfonate Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES.
T1476 Pramipexole SND 919 Dopamine Receptor
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not...
T1336 Benztropine mesylate Benzotropine mesylate,Benzatropine mesylate,Benztropine methanesulfonate Dopamine Receptor , AChR , Histamine Receptor
Benztropine mesylate (Benztropine methanesulfonate) is a centrally active muscarinic antagonist that has been used in the symptomatic treatment of PARKINSON DISEASE. Benztropine also inhibits the uptake of dopamine.
T6708 Tolcapone Tasmar,Ro 40-7592 Apoptosis , Beta Amyloid , Transferase
Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopa and carbidopa.
T6647 Rotigotine- Neupro,N-0923,N-0437,SPM 962 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome. Administered as a once-daily transdermal patch, Rotigotine has not been associated with ser...
T1476L Pramipexole dihydrochloride Dopamine Receptor
Pramipexole dihydrochloride could be used to treat Parkinson disease.
T21393 Ethopropazine Hydrochloride Lysivane,Parphezein,Dibutil,Parfezin,Profenamine HCl,Pardisol
Ethoproprazine hydrochloride is an butyrylcholinesterase inhibitor. It reduces extrapyramidal motor effects and used as an antidyskinetic, characteristic of Parkinson′s disease. It also alleviates thermal hyperalgesia in...
T34288 Repin
Repin, a plant responsible for Parkinson-like disease in horses, is the principal sesquiterpene lactone extracted from Russian knapweed.
T13252 (S)-Rasagiline TVP1022,S-PAI Others
(S)-Rasagiline is rasagiline S-isomer, and is an agent of anti-Parkinson.
T13252L (S)-Rasagiline mesylate TVP1022 (mesylate),S-PAI mesylate Others
(S)-Rasagiline mesylate is rasagiline S-isomer, and is an agent of anti-Parkinson.
T10908 CY 208-243 Dopamine Receptor
CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.
T69153 T0510-3657
T0510-3657 is a selective activator of GPR17, inhibiting cAMP levels, with potential for playing a key role in the development of a treatment against diseases such as, multiple sclerosis, Parkinson disease, Alzheimer's d...
T71174 PBT434 HBr
PBT434 is a novel, brain-penetrant, small molecule inhibitor of α-synuclein aggregation. In transgenic animal models of Parkinson disease (A53T) and MSA (PLP-α-Syn), PBT434 reduced α-synuclein aggregation, preserved neur...

Compounds

Nitecapone
T7831
Synonym:
Target: Others, Transferase
Budipine
T7626
Synonym:
Target: Others
CVN424
T9346
Synonym:
Target: GPR
PF-9601N
T8849
Synonym:
Target: MAO
Emraclidine
T9694
Synonym: CVL-231
Target: AChR
PSB-SB-487
T8975
Synonym:
Target: Cannabinoid Receptor
Propionylpromazine hydrochloride
T9228
Synonym: Propiopromazine hydrochloride
Target: Dopamine Receptor
B355252
T8869
Synonym:
Target: Others
ML-193
T22103
Synonym: CID 1261822
Target: Cannabinoid Receptor
A2A receptor antagonist 1
T37792
Synonym: CPI-444 analog,A2A receptor antagonist 1
Target: Adenosine Receptor
Brilaroxazine
T14782
Synonym: RP5063
Target: Dopamine Receptor, 5-HT Receptor
Ambroxol
T0920
Synonym: Ambroxolum,NA-872
Target: P450, Autophagy
Ambroxol hydrochloride
T6234
Synonym: Mucosolvan,Mucoangin,Ambroxol HCl
Target: Sodium Channel, Autophagy
Trihexyphenidyl hydrochloride
T7002
Synonym: Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride
Target: AChR
Lazabemide hydrochloride
T5678
Synonym: N-(2-Aminoethyl)-5-chlor-2-pyridincarbox
Target: MAO, Monoamine Oxidase
Etilevodopa hydrochloride
T24047
Synonym: Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester
Target: Others, Dopamine Receptor, Drug Metabolite
Mesdopetam hemitartrate
T9409
Synonym: IRL790 hemitartrate,1-​Propanamine, N-​[2-​[3-​fluoro-​5-​(methylsulfonyl)​phenoxy]​ethyl]​-​, (2R,​3R)​-​2,​3-​dihydroxybutanedioat​e (2:1)
Target: Dopamine Receptor
LAZABEMIDE
T5470
Synonym: Ro 19-6327
Target: MAO, Monoamine Oxidase
Safinamide mesylate
T6651
Synonym: PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate
Target: MAO, Monoamine Oxidase
Pozanicline dihydrochloride
T12525
Synonym: ABT-089 dihydrochloride
Target: AChR
Eliprodil
T1751
Synonym: SL-820715
Target: NMDAR, iGluR
Rivastigmine tartrate
T1628
Synonym: SDZ-ENA 713,ENA 713
Target: AChR, AChE
Eltoprazine dihydrochloride
T7746
Synonym:
Target: Others
Amantadine hydrochloride
T1406
Synonym: 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride
Target: Dopamine Receptor, Influenza Virus
Pimavanserin
T2076
Synonym: ACP-103
Target: 5-HT Receptor
Pergolide mesylate
T2226
Synonym: Pergolide mesylate salt,LY127809,Pergolide methanesulfonate
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Pramipexole
T1476
Synonym: SND 919
Target: Dopamine Receptor
Benztropine mesylate
T1336
Synonym: Benzotropine mesylate,Benzatropine mesylate,Benztropine methanesulfonate
Target: Dopamine Receptor, AChR, Histamine Receptor
Tolcapone
T6708
Synonym: Tasmar,Ro 40-7592
Target: Apoptosis, Beta Amyloid, Transferase
Rotigotine-
T6647
Synonym: Neupro,N-0923,N-0437,SPM 962
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Pramipexole dihydrochloride
T1476L
Synonym:
Target: Dopamine Receptor
Ethopropazine Hydrochloride
T21393
Synonym: Lysivane,Parphezein,Dibutil,Parfezin,Profenamine HCl,Pardisol
Target:
Repin
T34288
Synonym:
Target:
(S)-Rasagiline
T13252
Synonym: TVP1022,S-PAI
Target: Others
(S)-Rasagiline mesylate
T13252L
Synonym: TVP1022 (mesylate),S-PAI mesylate
Target: Others
CY 208-243
T10908
Synonym:
Target: Dopamine Receptor
T0510-3657
T69153
Synonym:
Target:
PBT434 HBr
T71174
Synonym:
Target:
Cat No. Product Name Synonyms Targets
TC0039 Vasicinone Others
Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiprolifer...
T0848 L-DOPA Levodopa,3,4-Dihydroxyphenylalanine Dopamine Receptor , Endogenous Metabolite
L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brai...
TN2011 Ombuoside Ombuin-3beta-rutinoside Antibacterial
Ombuoside (Ombuin-3beta-rutinoside) has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.Ombuoside is a glycoside ombuoside isolated from Gynostemma penta...
T4024 Norharmane 2-Azacarbazole,2,9-Diazafluorene,β-Carboline DNA , Endogenous Metabolite , Monoamine Oxidase
Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family.
T6795 Carbidopa (S)-(-)-Carbidopa,Lodosyn Decarboxylase , Aryl Hydrocarbon Receptor
Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA.
TN1140 Onjisaponin B AMPK , mTOR , Autophagy
Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parki...

Natural Products

Vasicinone
TC0039
Synonym:
Target: Others
L-DOPA
T0848
Synonym: Levodopa,3,4-Dihydroxyphenylalanine
Target: Dopamine Receptor, Endogenous Metabolite
Ombuoside
TN2011
Synonym: Ombuin-3beta-rutinoside
Target: Antibacterial
Norharmane
T4024
Synonym: 2-Azacarbazole,2,9-Diazafluorene,β-Carboline
Target: DNA, Endogenous Metabolite, Monoamine Oxidase
Carbidopa
T6795
Synonym: (S)-(-)-Carbidopa,Lodosyn
Target: Decarboxylase, Aryl Hydrocarbon Receptor
Onjisaponin B
TN1140
Synonym:
Target: AMPK, mTOR, Autophagy

Recombinant Proteins

Species：
Human (3)
Expression System：
E. coli (2)
HEK293 (1)
Tag：
His (3)
Cat No. Product Name Species Expression System
TMPY-02043 PARK7/DJ-1 Protein, Human, Recombinant (His) Human E. coli
Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress....
TMPY-02078 HtrA2/Omi Protein, Human, Recombinant (His) Human E. coli
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ...
TMPY-01303 Serpin A3 Protein, Human, Recombinant (His) Human HEK293
SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has be...
Cat No. Product Name
L9830 Anti-Parkinson's Disease Compound Library

908 compounds
A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.

Libraries

Anti-Parkinson's Disease Compound Library
L9830
Compounds: 908
CORPORATE
About Us Careers Privacy Notice Events & News Terms & Conditions
SUPPORT
Contact Us Worldwide Distributors Quality Control Technical Support
RESOURCE
Product Catalog Product Citations Signaling Pathways Solution Calculators
FOLLOW OUR
Social Network
Newsletter Subscription
Subscribe to receive our lastest product updates and special offers!
Corporate
Support
Resource
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
TargetMol
Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved.