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(2)
By Target- PROTACs
- Akt(1)
- GPCR(1)
- Histone Methyltransferase(1)
- Kras(1)
- Ras(1)
- VEGFR(1)
- Others(3)
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Results for "
ms21
" in TargetMol Product Catalog- Inhibitors & Agonists6
- PROTAC Products2
MS2133
T207647
MS2133 is a DOT1L PROTAC degrader. It facilitates the ubiquitination and degradation of DOT1L in THP-1 and MV4-11 cells, with DC50 values of 56 nM and 25 nM, respectively, and reduces H3K79 methylation. MS2133 also inhibits the growth of MLL-r leukemia cells, demonstrating anticancer activity.
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