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Results for "

mitf

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    18
    TargetMol | Inhibitors_Agonists
  • Peptide Products
    2
    TargetMol | Peptide_Products
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Methyl Linoleate
Telfairic Acid methyl ester, Linoleic acid methyl ester
T2P2810112-63-0
Methyl Linoleate (Telfairic Acid methyl ester) linoleate has antioxidant activity.
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Luteolin 7-sulfate
T1376256857-57-9
Luteolin 7-sulfate, derived from the marine plant Phyllospadix iwatensis Makino, suppresses TYR gene expression by intervening in a signaling pathway involving the cAMP-responsive element binding protein (CREB) and microphthalmia-associated transcription factor (MITF). This inhibition ultimately leads to a decrease in melanin synthesis.
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8-10 weeks
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Sesamol
3,4-Methylenedioxyphenol, 1,3-Benzodioxol-5-ol
T3676533-31-3
Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats. Sesamol ameliorates inflammatory and oxidative damage by upregulating AMPK activation and Nrf2 signaling and blocking the NF-κB and MAPK signaling pathways and inhibits melanin biosynthesis by down-regulating tyrosinase activity and melanin production via regulation of gene expression of melanogenesis-related proteins through modulation of MITF activity, which promotes phosphorylation of p38 and JNK in melan-a cells.
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6-Acetylnimbandiol
T755061281766-66-2
6-Acetylnimbandiol (6-O-Acetylnimbandiol), a non-cytotoxic tyrosinase inhibitor (IC 50 = 69.85 μM), effectively inhibits melanin production and MITF expression, making it valuable for melanoma research [1].
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N,N′-Diferuloylputrescine
T7999642369-86-8
N,N′-Diferuloylputrescine acts as a pigment inhibitor, showing a 57% reduction in pigmentation. It also considerably diminishes the protein expression of MITF and displays potent antioxidant properties as a radical scavenger against reactive oxygen species [1].
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Trans-caffeic acid
3,4-Dihydroxybenzeneacrylic acid
TMA0003501-16-6
Trans-caffeic acid (3,4-Dihydroxybenzeneacrylic acid) can be used as a highly sensitive fluorescent probe for the detection of laccase in food and can also stimulate the growth of germ tissue.
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Swertiajaponin
TN22466980-25-2
Swertiajaponin possesses antimicrobial activity.
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Haginin A
TN417974174-29-1
Haginin A is an effective inhibitor of hyperpigmentation caused by UV irradiation or by pigmented skin disorders through downregulation via ERK and Akt PKB activation, MITF, and also by the subsequent downregulation of tyrosinase and TRP-1 production. Hag
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(-)-Lyoniresinol 9'-O-glucoside
TN4468143236-02-6
(-)-Lyoniresinol 9'-O-glucoside is a natural product derived from Phyllostachys heterocycla [MITF].
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Manassantin A
TN448988497-87-4
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX PGE2 stimulation, inhibition of iNOS production and NF-κB act
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