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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12367 | Parsaclisib | INCB050465 | PI3K |
Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 mM ATP) | |||
T12317 | Orelabrutinib | ICP-022 | BTK |
Orelabrutinib (ICP-022) is an orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK). | |||
T6055 | Quisinostat | JNJ-26481585 | Apoptosis , HDAC , Autophagy |
Quisinostat (JNJ-26481585) (JNJ-26481585) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against... | |||
T6761 | Ossirene | AS101 | IL Receptor , Caspase , Interleukin |
Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme. | |||
T12477 | Uzansertib phosphate | INCB053914 phosphate | Pim |
Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively). | |||
T22349 | JNJ-38158471 | CS-2660 | VEGFR , c-RET , c-Kit |
JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor with IC50 of 40 nM, inhibits closely related tyrosine kinases such as Ret and Kit with IC50 of 180 nM and 500 nM. | |||
T12311 | Tirabrutinib hydrochloride | ONO-4059 (hydrochloride),GS-4059 (hydrochloride) | BTK |
Tirabrutinib hydrochloride (GS-4059 (hydrochloride)) is a selective and novelBTK with IC50 2.2 nm inhibitor. | |||
T4976 | Umbralisib | TGR-1202,RP5264,TGR 1202,TGR1202 | PI3K |
Umbralisib (TGR 1202) is a PI3Kδ inhibitor. | |||
T0975 | Chlorambucil | CB-1348,Chloroambucil,WR-139013 | DNA Alkylator/Crosslinker , DNA Alkylation |
Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arr... | |||
T1038 | Fludarabine | NSC 118218,Fludarabinum,F-ara-A | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , STAT |
Fludarabine (Fludarabinum) is a nucleic acid synthesis Inhibitor and a STAT1 activation inhibitor. | |||
T6079 | NVP-ADW742 | ADW742,ADW,GSK 552602A | Apoptosis , IGF-1R |
NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit. | |||
T12574 | PTC299 | Emvododstat,(4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate | VEGFR , Dehydrogenase |
PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA translation and selectively inhibits VEGF protein synthesis at t... | |||
T6104 | Cerdulatinib hydrochloride | Cerdulatinib,PRT2070,PRT062070 hydrochloride,PRT062070,PRT2070 hydrochloride | MLK , c-Fms , Tyrosine Kinases , Hippo pathway , JAK , Syk |
Cerdulatinib hydrochloride (PRT2070 hydrochloride) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19... | |||
T6865 | Quisinostat dihydrochloride | Quisinostat 2HCl,Quisinostat (JNJ-26481585) 2HCl,JNJ26854165(Quisinostat) 2HCl,JNJ-26481585 2HCl | Apoptosis , HDAC , Autophagy |
Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; g... | |||
T28297 | Parsaclisib hydrochloride | Parsaclisib HCl,INCB-50465,INCB 050465,INCB-050465,INCB050465 HCl,INCB 50465,INCB50465 HCl | PI3K |
Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent activity with IC50 values ranging from 0.2 to 2 nM. | |||
T10436 | AZD4573 | CDK | |
AZD4573 is an effective and selective CDK9 inhibitor (IC50: <4 nM). It enables transient target engagement for the treatment of hematologic malignancies. | |||
T1601 | Lomustine | CCNU,NSC 79037 | Apoptosis , Others , DNA Alkylator/Crosslinker , DNA Alkylation , Autophagy |
Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors. | |||
T23903 | CM037 | CM-037,A-37,CM 037,A37,A 37 | Dehydrogenase |
CM037 (A-37) is a selective ALDH1A1 (acetaldehyde dehydrogenase 1A1) inhibitor (IC50; 4.6 µM) with antitumor activity and may be used in studies to eliminate gynecologic malignancies. | |||
TNU0014 | 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil | Apoptosis | |
1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a purine nucleoside analog with a broad spectrum of antitumor activity targeting inert lymphoid malignancies and inducing apoptosis.1-(2-Deoxy-2-fluoro-beta-D-arabino... | |||
T9756 | AZD-9574 | PARP | |
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and advanced solid malignancies. | |||
T1962 | ASP3026 | ASP 3026 | Apoptosis , ALK |
ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies, Positive for Anaplastic Lymphoma Kinase, and Positive for Proto-Oncogene Tyrosine-Protein Kinase ROS. | |||
T7221 | Satraplatin | BMS182751,JM216,BMY45594 | DNA Alkylator/Crosslinker , DNA Alkylation |
Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against a variety of malignancies. | |||
TNU0352 | 1-beta-D-Arabinofuranosylthymine | Thymine 1-β-D-arabinofuranoside,Spongothymidine | Apoptosis |
1-beta-D-Arabinofuranosylthymine (Thymine 1-β-D-arabinofuranoside) is a purine nucleoside analog. Purine nucleoside analogs have a broad spectrum of antitumor activity, targeting inert lymphoid malignancies and inducing ... | |||
T3069 | AZD-1480 | JAK | |
AZD1480 is a novel ATP-competitive JAK2 inhibitor (IC50: 0.26 nM), selectivity act against Tyk2 and JAK3, and to a smaller extent against JAK1. AZD1480 has been used in trials studying the treatment of Solid Malignancies... | |||
T76705 | Utomilumab | PF 05082566,PF-2566 | TNF |
Utomilumab (PF 05082566) is a humanized IgG2 antibody targeting the T-cell co-stimulatory receptor 4-1BB/CD137 and a 4-1BB/CD137 agonist.Utomilumab has antitumor activity and may be used in the study of patients with adv... | |||
T63788 | PCLX-001 | Others | |
PCLX-001 is a small-molecule compound that acts as an orally active inhibitor of N-myristoyltransferase (NMT), specifically targeting NMT1 and NMT2 with IC50 values of 5 nM and 8 nM, respectively. This compound demonstra... | |||
T17028 | Tefinostat | CHR-2845 | HDAC |
Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor. Tefinostat is cleaved to the active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1).Tefino... | |||
T4428 | CCT241736 | FLT , Aurora Kinase | |
CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3, CCT241736, an advanced analog of CCT137690, is a preclinica... | |||
T68316 | GAC0003A4 | GAC0001E5 | Liver X Receptor |
GAC0003A4 is a potent LXR inverse agonist with antitumor activity that inhibits the transcription of LXR proteins.GAC0003A4 degrades LXRβ proteins and inhibits the proliferation of PDAC cells in a dose-dependent manner.G... | |||
TQ0236 | Tirabrutinib | ONO-4059,GS-4059,Velexbru | BTK |
Tirabrutinib (GS-4059) (ONO-4059) is an orally active Bruton’s Tyrosine Kinase (Btk) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to Btk and ... | |||
T3626 | Acalabrutinib | ACP-196 | BTK |
Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and pre... | |||
T38960 | QL-X-138 | Virus Protease , MNK , BTK | |
QL-X-138 is a potent and selective BTK and MNK dual kinase inhibitor that binds covalently to BTK and non-covalently to MNK.The IC 50 s of QL-X-138 against BTK, MNK1 and MNK2 kinases are 9.4 nM, 107.4 nM and 26 nM, respe... | |||
T19661 | 8-Chloroadenosine | NSC 354258,8-Cl-Ado,NSC354258,NSC-354258 | AMPK |
8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia. 8-chloroadenosine activity is associated with inhibition of the mTOR pathway.8-Ch... | |||
T36083 | DS-7423 | PI3K , mTOR | |
DS-7423 is a dual PI3K and mTOR inhibitor, with IC50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR, respectively. DS-7423 possesses anti-tumor activity[1][2]. DS-7423 increases TP53 expression, the level of p-TP53 on Ser... | |||
T36944 | Ara-G | Nucleoside Antimetabolite/Analog | |
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate... | |||
T20858 | Metanilic acid | m-Anilinesulfonic acid,m-Sulfanilic acid | |
Metanilic acid, an anti-cancer drug, is used to treat several malignancies including choriocarcinoma and pediatric acute lymphoblastic leukemia. | |||
T27274 | EP009 | ||
EP009, a novel, selective, and orally active inhibitor of JAK3, induces therapeutic response in T-cell malignancies. | |||
T27558 | HT1042 | HT 1042,HT-1042 | |
HT1042 is an inhibitor of the β5i component of the 20S proteasome complex, it is used to aid in the treatment of inflammatory diseases, autoimmune and hematologic malignancies. | |||
T11603 | Ibrutinib-MPEA | Others | |
Ibrutinib-MPEA is ibrutinib derivative. Ibrutinib is a covalent and irreversible BTK inhibitor that has been used to treat hematological malignancies. | |||
T11544 | HDACs/mTOR Inhibitor 1 | HDAC | |
HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM, 1.2 nM, and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα). | |||
T68411 | AT-7519M | ||
AT-7519M is a small molecule inhibitor of cyclin-dependent kinases 1, 2, 4, 5, and 9 with in vitro activity against lymphoid malignancies. | |||
T70759 | CUDC-907 mesylate | ||
CUDC-907 mesylate is a small molecule inhibitor of histone deacetylase and PI3 kinase developed by Curis. It is investigated in clinical trials for the treatment of relapsed or refractory lymphomas, thyroid cancer, multi... | |||
T21329 | Gemcitabine monophosphate disodium salt | Gemcitabine monophosphate disodium salt monohydrate,Gemcitabine monophosphate disodium,GemMP | |
R306465 is a novel HDAC inhibitor with broad-spectrum antitumor activity against solid (IC50: 30 to 300 nM) and hematological malignancies. R306465 was found to be a potent inhibitor of HDAC1 and -8 (class I) in vitro. | |||
T2610 | BMS-599626 | AC480 | EGFR , MEK , HER , Src |
BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies. | |||
T22859 | Imatinib hydrochloride | Others | |
Imatinib is a multi-target inhibitor of v-Abl, c-Kit, and PDGFR (IC50: 0.6 μM, 0.1 μM, and 0.1 μM, respectively). Imatinib is used to treat chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs), and... | |||
T79067 | PROTAC BTK Degrader-3 | PROTACs | |
PROTAC BTK Degrader-3 is a potent degrader of Bruton's tyrosine kinase (BTK), exhibiting a DC50 (median degradation concentration) of 10.9 nM in Mino cells. This compound shows promise for research into B-cell malignanci... | |||
T62896 | EZH2-IN-12 | ||
EZH2-IN-12 (Compound 5) is a potent inhibitor of EZH2, which has potential for studies of CNS malignancies. | |||
T63497 | PI3Kδ/γ-IN-1 | ||
PI3Kδ/γ-IN-1 is a selective and effective inhibitor of PI3Kδ/γ that can be used in the treatment of hematologic malignancies. | |||
T79840 | Bocodepsin hydrochloride | OKI-179 hydrochloride | HDAC |
Bocodepsin hydrochloride (OKI-179) is a selective HDAC inhibitor with antitumor properties, efficacious via oral administration. It is employed in the suppression of both solid tumors and hematological malignancies [1]. | |||
T76929 | Betifisolimab | ||
Betifisolimab (MSB-2311) is a humanized monoclonal antibody directed against the immunosuppressive ligand PD-L1 . Betifisolimab has the potential for advanced solid tumors and hematological malignancies research [1] . |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9715 | Aplidine | SARS-CoV , DNA/RNA Synthesis | |
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM). | |||
TNU0052 | Nebularine | 9-(beta-D-Ribofuranosyl)-9H-purine | Apoptosis |
Nebularine (9-(beta-D-Ribofuranosyl)-9H-purine) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting inert lymphoid malignancies and inducing apoptosis.The anticancer mechanism of Nebulari... | |||
T3380 | Homoharringtonine | Myelostat,Ceflatonin,HHT,Omacetaxine mepesuccinate | STAT |
Homoharringtonine (HHT) is an alkaloid inhibitor of protein synthesis with activity in myeloid malignancies. It might have clinical activity in some patients with myelodysplastic syndrome. Homoharringtonine enhances the ... | |||
T35000 | Uproleselan sodium | GMI 1271,GMI1271,GMI-1271 | |
Uproleselan sodium (GGI-1271) is a small molecule E-selector antagonist originally targeted at AML as an adjuvant to standard chemotherapy for hematological malignancies. | |||
T12403 | Penitrem A | Others | |
Penitrem A is a selective antagonist of BK channel with antiproliferative and anti-invasive activities against multiple malignancies. | |||
TN2299 | Vindesine | Others | |
Vindesine is a microtubule inhibitor and widely used to treat malignancies. Vindesine neuropathy seems to be the cause of the patient's neurological symptoms. | |||
T16035 | Meleagrin | Others | |
Meleagrin is a class of FabI inhibitors. Meleagrin is a lead c-Met inhibitory entity useful for the control of c-Met-dependent metastatic and invasive breast malignancies. Meleagrin is a roquefortine C-derived alkaloid p... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01257 | UPAR/PLAUR Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ... | |||
TMPY-04289 | CD30L Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell s... | |||
TMPY-00705 | CD30L Protein, Human, Recombinant (hFc) | Human | HEK293 |
CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell s... | |||
TMPY-02141 | UPAR/PLAUR Protein, Human, Recombinant (His) | Human | HEK293 |
Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and ... | |||
TMPY-05446 | CD200 Protein, Human, Recombinant (hFc) | Human | HEK293 |
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ... | |||
TMPY-06842 | BMP-4 Protein, Human, Recombinant (E399D) | Human | E. coli |
BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP... | |||
TMPY-00970 | CD31/PECAM-1 Protein, Human, Recombinant (His) | Human | HEK293 |
The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transm... | |||
TMPY-01896 | HGFR/c-Met Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR... | |||
TMPY-00548 | HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR... | |||
TMPY-01296 | HGFR/c-Met Protein, Human, Recombinant (His) | Human | HEK293 |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR... | |||
TMPY-01827 | CD30/TNFRSF8 Protein, Human, Recombinant (His) | Human | HEK293 |
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of... | |||
TMPY-02030 | CD82 Protein, Human, Recombinant (His) | Human | HEK293 |
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetras... | |||
TMPY-02566 | Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Interferon, alpha 4 (IFNA4) belongs to the alpha/beta interferon family. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 an... | |||
TMPY-01423 | OX40/TNFRSF4 Protein, Human, Recombinant (His) | Human | HEK293 |
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea... | |||
TMPY-01068 | CD70 Protein, Human, Recombinant (hFc) | Human | HEK293 |
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor, CD27, is important in priming, effector functions, diff... | |||
TMPY-04803 | DLL4 Protein, Human, Recombinant | Human | HEK293 |
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud... | |||
TMPY-01321 | DLL4 Protein, Human, Recombinant (His) | Human | HEK293 |
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud... | |||
TMPY-01337 | DLL4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud... | |||
TMPY-00776 | DLL4 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud... | |||
TMPY-05094 | Tissue Factor Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-02530 | Tissue Factor Protein, Human, Recombinant (His) | Human | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-03644 | CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-03776 | CD25/IL2R alpha Protein, Cynomolgus, Recombinant | Cynomolgus | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-05644 | CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated | Rhesus | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-01923 | CD25/IL2R alpha Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-03713 | GM-CSF/CSF2 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio... | |||
TMPY-05090 | CD25/IL2R alpha Protein, Rat, Recombinant (His) | Rat | Baculovirus-Insect Cells |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-01103 | CD25/IL2R alpha Protein, Human, Recombinant (His) | Human | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-05584 | CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ... | |||
TMPY-00750 | GM-CSF/CSF2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio... | |||
TMPY-03662 | GM-CSF/CSF2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio... | |||
TMPY-03858 | GM-CSF/CSF2 Protein, Human, Recombinant | Human | HEK293 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio... | |||
TMPY-04114 | GM-CSF/CSF2 Protein, Mouse, Recombinant | Mouse | HEK293 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestatio... | |||
TMPK-00008 | CCL5 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the role of the CCL5/CCR axis were performed only in a limited n... | |||
TMPK-00618 | FcRH5/FcRL5 Protein, Human, Recombinant (His) | Human | HEK293 |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),... | |||
TMPK-01039 | FcRH5/FcRL5 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),... | |||
TMPK-00009 | CCL5 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | E. coli |
The CCR5 and the CCL5 ligand have been detected in some hematological malignancies, lymphomas, and a great number of solid tumors, but extensive studies on the role of the CCL5/CCR axis were performed only in a limited n... | |||
TMPK-00619 | FcRH5/FcRL5 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated | Human | HEK293 |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),... | |||
TMPK-01145 | FcRH5/FcRL5 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE),... | |||
TMPK-00800 | CDH3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been prove... | |||
TMPK-01306 | CDH3 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been prove... | |||
TMPK-00851 | CDH3 Protein, Human, Recombinant (aa 108-654, His) | Human | HEK293 |
Placental-Cadherin (CDH3), a cell adhesion molecule, is associated with the function of cells to bind with other cells and the extracellular matrix (ECM). CDH3 is highly expressed in many malignancies, and has been prove... | |||
TMPY-03748 | BCL2L12 Protein, Human, Recombinant (GST) | Human | E. coli |
BCL2-like 12 (BCL2L12 ) is a new member of the apoptosis-related BCL2 gene family, members of which are implicated in various malignancies. The mRNA expression of BCL2L12 may constitute a novel biomarker for the predicti... | |||
TMPK-00270 | TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled | Human | HEK293 |
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR... | |||
TMPK-00271 | TPBG/5T4 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR... | |||
TMPY-03239 | CD30L Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell s... | |||
TMPY-03582 | CD30L Protein, Rat, Recombinant | Rat | HEK293 |
CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell s... | |||
TMPY-04581 | CD30L Protein, Human, Recombinant | Human | HEK293 |
CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell s... | |||
TMPK-00812 | Midkine Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue hom... | |||
TMPY-03001 | CD52 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view t... | |||
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Cat No. | Product Name | ||
---|---|---|---|
L8400 | Hematonosis Compound Library | 524 compounds | |
A unique collection of 524 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS); | |||
L2194 | Anti-Colorectal Cancer Compound Library | 1565 compounds | |
1565 compounds associated with colorectal cancer that can be used for high-throughput and high-content screening. | |||
L4300 | Wnt/Hedgehog/Notch Compound Library | 240 compounds | |
A unique collection of 240 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening; | |||
L6740 | Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library | 386 compounds | |
A collection of 386 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies. |