lglutathione

Glutathione oxidized (L(-) -glutathione) is the oxidized form of Glutathione, which is a major antioxidant and antidote in cells. Glutathione oxidized can be used to study sickle cells and red blood cells.

L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is involved in the rearrangement of protein disulfide bonds and the reduction of peroxides.

Glutathione can occur in reduced (GSH), oxidized (GSSG), or in mixed disulfide forms and is ubiquitous in multiple biological systems serving as the major thiol-disulfide redox buffer of the cell. GSSG is the oxidized form of GSH . It can be reduced back to GSH through the NADPH-dependent enzyme glutathione reductase. GSSG functions as a hydrogen acceptor in the enzymatic determination of NADP+ and NADPH and can be a proximal donor in S-glutathionylation post translational modifications. The ratio of reduced glutathione to oxidized glutathione within cells is often used as an indicator of oxidative stress, with higher concentrations of GSSG predicting increased oxidative stress.

S-Methylglutathione (S-Methyl glutathione) is an S-substituted glutathione, an inhibitor of the 1-chloro-2,4-dinitrobenzene coupling catalyzed by transferase A and an XOCl scavenger.S-Methylglutathione inhibits glyoxalase 1 (glyoxalase 1), which induces the development of the glyoxalase 1 enzyme. S-Methylglutathione inhibits glyoxalase 1 (glyoxalase 1) and induces the formation of hydroid tentacle balls.

Hexylglutathione, a glutathione-S-transferase inhibitor, is used to study the effects of phase II enzymes and glutathione.

S-Octylglutathione is a competitive inhibitor of glutathione S-transferase (GST) [1].

S-Benzylglutathione acts as a competitive inhibitor of glutathionase and undergoes conversion by rat kidney microsomes into its cysteine derivatives. It is utilized in studies concerning the metabolic degradation of glutathione via the glutathionase system [1].

S-Octylglutathione-CoA (S-Octylglutathione-coenzyme A) is a derivative of coenzyme A.

BrBzGCp2 (p BrBzGSH(Cp)2) is an inhibitor of glyoxalase 1 (GLO1) with antitumor and neuroprotective activity. It can alleviate anxiety and be used in neurodegenerative disease research.

Dansyl glutathione is a capture agent used for quantitative assessment and identification of reactive metabolites.

Bis(DNS-glutathione) disulfide is a synthetic polypeptide composed of repeating α-L-glutamic acid units. Poly-DNS-glutathione is recognized for its biocompatibility, biodegradability, and non-immunogenic nature, making it highly suitable for advanced drug-delivery system engineering. Bis(DNS-glutathione) disulfide has been extensively employed in the creation of nanomaterials designed to improve drug loading, controlled release, and targeted biodistribution, ultimately supporting the development of safer and more efficient therapeutic delivery platforms.

S-Ethyl glutathione is the enzyme Glyoxalase 1 inhibitor.

S-Acetyl-L-glutathione is a derivative of glutathione .1 It increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency when used at a concentration of 50 μM. S-Acetyl-L-glutathione (5 mM) induces apoptosis in Daudi, Raji, and Jurkat lymphoma cells.2 It inhibits the replication of herpes simplex virus 1 (HSV-1) in human foreskin fibroblasts when used at concentrations of 5 and 10 mM.3 S-Acetyl-L-glutathione (6.25 μg/g per day) increases survival in a mouse model of HSV-1 infection.

S-Geranylgeranyl-L-glutathione acts as a ligand for the orphan G protein-coupled receptor (GPCR) P2RY8, displaying selective affinity by inducing internalization of P2RY8 in preference to the sphingosine-1-phosphate receptor 2 (S1P2), GPR55, cysteinyl leukotriene receptor 1 (CysLT1 receptor), and the CysLT2 receptor at a concentration of 100 nM. Additionally, at a lower concentration of 10 nM, S-Geranylgeranyl-L-glutathione inhibits the chemokine (C-X-C motif) ligand 12-induced migration of both P2RY8-expressing WEHI-231 B cell lymphoma cells and human tonsil germinal center B cells.

L-Glutathione reduced-13C2,15N is an isotopically labeled variant of L-Glutathione reduced, incorporating both 13C and 15N. L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) functions as an endogenous antioxidant, capable of scavenging oxygen free radicals.

L-Glutathione reduced (Standard) is a reference standard for research and analysis in studies involving L-Glutathione reduced. L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is involved in the rearrangement of protein disulfide bonds and the reduction of peroxides.

4-Hydroxy nonenal glutathione (4-HNE-GSH) TFA is the primary metabolite of 4-hydroxy-2-nonenal. It serves as a marker for oxidative stress in rat liver and hepatocytes. Additionally, 4-Hydroxy nonenal glutathione TFA effectively prevents the formation of 4-hydroxy-2-nonenal-DNA adducts in human cells.

S-Benzyl-glutathione-CoA (S-Benzyl-glutathione-coenzyme A) is a derivative of coenzyme A.

S-Methyl-glutathione-CoA (S-Methyl-glutathione-coenzyme A) is a derivative of coenzyme A.

S-Hydroxymethyl-glutathione-CoA (S-Hydroxymethyl glutathione-coenzyme A) is a derivative of coenzyme A.