immunoregulation

Sodium taurocholate is a biologically active compound that can inhibit bile duct injury induced by hepatic artery ligation by upregulating VEGF-A expression. It also exhibits immunomodulatory effects and can be used to induce pancreatitis models.

Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and steviolbioside, have many biological activities, such as reducing blood glucose, lowering blood pressure, anti-inflammation, anti-tumor, anti-diarrhea, antibacterium, immunoregulation, etc.

PTPN22-IN-2 (Compound 8b-19) is a PTPN22 inhibitor with an IC50 of 250 nM and is applicable in immunoregulation research.

(±)5(6)-EET Ethanolamide is a metabolite derived from Anandamide through oxidation by cytochrome P450 enzymes. It acts as a selective cannabinoid receptor 2 (CB2) agonist. The Ki values for (±)5(6)-EET Ethanolamide against human CB1 and CB2 are 11.4 μM and 8.9 nM, respectively. This compound can be used in studies related to immunoregulation and neuroinflammation.

Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity in cultured cells and animal systems.

Zectivimod, a sphingosine-1-phosphate receptor agonist, holds the potential for studying autoimmune diseases, chronic inflammatory diseases, and immunoregulation disorders.

TIM-3-IN-1 is a useful tool to enable further studies on the biology of TIM-3 immunoregulation in cancer.

Diminazene is an aromatic diamine compound primarily used to control trypanosomiasis. It mainly binds to the kDNA of trypanosomes, disrupting their replication process. Diminazene is being investigated for new pharmacological applications, such as an activator of angiotensin-converting enzyme 2 (ACE2), and has potential uses in antihypertension, anti-rheumatoid arthritis, and immunoregulation.

Isosteviol (Standard) is a reference standard for research and analysis in studies involving Isosteviol. Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and steviolbioside, have many biological activities, such as reducing blood glucose, lowering blood pressure, anti-inflammation, anti-tumor, anti-diarrhea, antibacterium, immunoregulation, etc.

Formosanin C (Standard) is a reference standard for research and analysis in studies involving Formosanin C. Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity in cultured cells and animal systems.