hydroquinone

Hydroquinone monobenzoate is an oxidoreductant and potential topoisomerase II inhibitor commercially used in skin whitening treatments and photography development. It may induce DNA damage.

Hydroquinone diacetate (NSC-9277) is an OH• inibitor with IC50 of 7.59 μM.

3-Hydroxypropanoic acid-pip-hydroquinone-dihydrouracil is a crucial intermediate in the synthesis of the complete PROTACHPK1 Degrader-2, serving as a conjugate (conjugate) of E3 ligase ligand and linker.

Apaziquone (EOquin, EO9) is an indolequinone compound that acts as a bioreductive prodrug. It is chemically similar to the earlier chemotherapy compound mitomycin C.

Trimethylhydroquinone is a strongly reducing derivative of hydroquinone, a key intermediate in the synthesis of vitamin E, and is widely used in biochemical experiments and drug synthesis research.

2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.

2,3-Dimethylhydroquinone exhibits inhibitory activity against cancer cells such as MDA-MB-231, HT-29, HT-1080, and HL-60 with an IC50 of 1.6–6.5 μM, and demonstrates antifungal activity against Candida krusei Berkouet.

Thymohydroquinone (Thymoquinol) is a monoterpenoid phenolic compound found in thyme, oregano, and other plants in the labiaceae family. Thymohydroquinone inhibits cancer cell growth, reduces oxidative stress and modulates inflammatory responses, scoured 2, 2-diphenyl-1-PicrylHydrazyl radicals in a cell-free assay (IC50 = 2.4 μg/ml), In the oxygen radical absorption capacity (ORAC) test at concentrations of 1.6 to 6.4 μg/ml, Its Trolox value was 2.6. Thymus hydroquinone inhibited the growth of A2780, OVCAR-8 and CIS-A2780 ovarian cancer cells (IC50 were 3.1, 8.9 and 9.8 μM, respectively) and human ovarian immortalized epithelial cells (IC50 = 14 μM). It also inhibited Plasmodium falciparum in vitro (IC50 = 15.9 μM).

Tetrachlorohydroquinone dimethyl ether is a useful organic compound for research related to life sciences and the catalog number is T123888.

2-Prenylhydroquinone-1-glucoside is a useful organic compound for research related to life sciences and the catalog number is T131092.

2-Methoxyhydroquinone inhibits MAO-A and MAO-B and reduces TNF-α-induced CCL2 production, often serving as a precursor for synthesising the Hsp90 inhibitor Geldanamycin.

Tetrachlorohydroquinone (TCHQ), a metabolite of the organochlorine biocide pentachlorophenol, is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of mitochondrial membrane potential and necrosis in splenocytes.

2,6-Dimethylhydroquinone (2,6-DMHQ), an endogenous metabolite, consists of a benzene ring substituted with two hydroxyl (OH) groups located at positions 1 and 4, along with two methyl (CH3) groups at positions 2 and 6. [2,6-dimethylbenzene-1,4-diol]

2,5-Di-tert-butylhydroquinone (Standard) is the standard substance of 2,5-Di-tert-butylhydroquinone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.

Colutehydroquinone is an antifungal isoflavonoid from Colutea arborescens.

TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.

Vitamin K1 (Phylloquinone) a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity.

2,5-Dihydroxybenzoic acid (Gentisic acid) is an active metabolite of salicylic acid degradation with a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant properties.

1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPKs, it also can potentiate the pro-apoptotic and anti-proliferative effects of bortezomib in U266 cells. 3. 2,5-Dihydroxyacetophenone (Quinacetophenone) has anti-inflammatory activity in activated macrophages, raising the possibility that this compound has a therapeutic potential for inflammatory conditions. 4. 2,5-Dihydroxyacetophenone (Quinacetophenone) is an uncompetitive inhibitor of murine tyrosinase (K(I) 0.28mm), it strongly inhibits both melanogenesis and cellular tyrosinase activity in vitro in 3-isobutyl-1-methylxanthin-stimulated B16 mouse melanoma cells or in vivo in zebrafish and mouse models.

HTHQ (HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone)), a hydroquinone monoalkyl ether, is an effective anti-oxidative agent. HTHQ is a potent anti-lipid-peroxidative compound and its antioxidation activity to be extremely elevated in biological systems, such as that of liver microsomes via the generation of stable free radicals.

Alboleersin is a biochemical.

TBHQ (Standard) is the standard substance of TBHQ, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.

Arbutin (p-Arbutin)(β-Arbutin) is a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos and can inhibit tyrosinase and thus prevent the formation of melanin.

Mequinol (Leucobasal) is a synthetic derivate of hydroquinone and depigmenting agent. Although the exact mechanism of the depigmenting effects of mequinol remains unclear, it may exert its effect by oxidation of tyrosinase to cytotoxic products in melanocytes.