gram-negative aerobic bacteria

Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics. Its activity was similar to oxolinic acid and nalidixic acid.

Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation of mRNA and inhibition of protein synthesis followed by cell death. Paromomycin Sulfate (Aminosidine sulfate) is the sulfate salt form of paromomycin, a structural derivative of neomycin, an aminoglycoside antibiotic with amebicidal and bactericidal effects against predominantly aerobic gram-negative bacteria.

Ticarcillin sodium (Aerugipen hydrate) is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.

Cefotetan Sodium, a second-generation cephalosporin, cephamycin antibiotic, is active against a wide range of both aerobic and anaerobic gram-negative and gram-positive bacteria. Cefotetan disrupts the cell wall synthesis by binding to penicillin-binding

Azthreonam monosodium salt is a synthetic monobactam specifically active against aerobic gram-negative bacteria.

A-39183A is an active component of the A-39183 antibiotic complex produced by aerobic fermentation of Streptomyces NRRL 12049. It has activity against penicillin-resistant S. aureus 3055 and S. faecalis X66 (MICs = 32 and 32 μg/ml, respectively) and a variety of Gram-positive and Gram-negative anaerobic bacteria (MICs = 16-128 μg/ml) in an agar dilution assay.

Dicloxacillin Sodium (BRL1702 Sodium) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive negative aerobic and anaerobic bacteria.

Cefotetan (Apacef) Sodium (ICI-156834, YM-09330) is a second-generation cephalosporin, cephamycin antibiotic that is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative bacteria. Cefotetan binds to penicillin-binding proteins and disrupts the cell wall synthesis.

Cefepime chloride (BMY-28142) is a broad-spectrum cephalosporin that can cross the blood-brain barrier and exhibits antibacterial activity against both Gram-positive and Gram-negative aerobic bacteria. It also induces neurotoxicity.

Temocillin, a semisynthetic 6-alpha-methoxy penicillin derivative, is a beta-lactam antibiotic. It exhibits a spectrum of activity primarily against aerobic Gram-negative bacteria [1].

Trimethoprim hydrochloride, a bacteriostatic antibiotic and dihydrofolate reductase inhibitor, demonstrates efficacy against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria. It has research applications for urinary tract infections, Shigellosis, and Pneumocystis pneumonia. Additionally, when combined with zinc, it can inhibit the infection of Influenza A virus in chick embryos [1] [2] [3] [4].

Cefiderocol (S-649266) is a novel iron-siderophore-cephalosporin conjugate with antibacterial activity, inhibiting aerobic Gram-negative bacteria, used in bacterial infection research.

Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with broad-spectrum activity against both Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial properties, without the adverse hemolytic effects commonly associated with bee venom peptides [1].

Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive negative, anaerobic and aerobic bacteria encountered by domestic animals.