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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3716 | Rolapitant | SCH619734 | Neurokinin receptor |
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ... | |||
T22019 | ABT 724 trihydrochloride | Dopamine Receptor | |
ABT 724 trihydrochloride is an effective and selective agonist of the D4 receptor (EC50 = 12.4 nM, 14.3 nM, and 23.2 nM for human, rat and ferret, respectively). ABT-724 trihydrochloride can be used in erectile dysfuncti... | |||
T3724 | Rolapitant hydrochloride | Rolapitant HCl | Neurokinin receptor |
Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant hydrochloride (Rolapitant HCl) does not interact with CY... | |||
T24102 | GR-203040 HCl | GR 203040,GR-203040 hydrochloride,GR-203040,GR203040 | |
GR203040 inhibits cyclophosphamide-induced damage in the rat and ferret bladder. GR-203040 is a selective NK1 receptor antagonist. | |||
T14088 | ABT-670 | Dopamine Receptor | |
ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and rat D4, the EC50 values are 89 nM, 160 nM, and 93 nM , respectively. | |||
T13329 | Vofopitant | GR 205171 | Neurokinin receptor |
Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD). |
Cat No. | Product Name | Species | Expression System |
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TMPY-02218 | CD20 Protein, Ferret, Recombinant (His) | Ferret | HEK293 |
CD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features ... | |||
TMPY-02226 | TNF alpha Protein, Ferret, Recombinant | Ferret | E. coli |
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological... | |||
TMPY-02182 | CD4 Protein, Ferret, Recombinant (His) | Ferret | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre... | |||
TMPY-02165 | CD8 alpha Protein, Ferret, Recombinant (His) | Ferret | HEK293 |
T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp... | |||
TMPY-03664 | IFN gamma Protein, Ferret, Recombinant (His) | Ferret | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPK-00583 | TNF alpha Protein, Ferret, Recombinant (His) | Ferret | E. coli |
Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system developm... |